An update on the progress of microbial biotransformation of commercial monoterpenes

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Ruchika Mittal ◽  
Gauri Srivastava ◽  
Deepak Ganjewala
Keyword(s):  
Web Of Science ◽  
Alternative Methods ◽  
Biosynthetic Pathways ◽  
Chemical Methods ◽  
Geranyl Diphosphate ◽  
The Past ◽  
Bioactive Properties ◽  
Pharmacological Significance ◽  
Commercially Important ◽  
Extract Information

Abstract Monoterpenes, a class of isoprenoid compounds, are extensively used in flavor, fragrance, perfumery, and cosmetics. They display many astonishing bioactive properties of biological and pharmacological significance. All monoterpenes are derived from universal precursor geranyl diphosphate. The demand for new monoterpenoids has been increasing in flavor, fragrances, perfumery, and pharmaceuticals. Chemical methods, which are harmful for human and the environment, synthesize most of these products. Over the years, researchers have developed alternative methods for the production of newer monoterpenoids. Microbial biotransformation is one of them, which relied on microbes and their enzymes. It has produced many new desirable commercially important monoterpenoids. A growing number of reports reflect an ever-expanding scope of microbial biotransformation in food and aroma industries. Simultaneously, our knowledge of the enzymology of monoterpene biosynthetic pathways has been increasing, which facilitated the biotransformation of monoterpenes. In this article, we have covered the progress made on microbial biotransformation of commercial monoterpenes with a brief introduction to their biosynthesis. We have collected several reports from authentic web sources, including Google Scholar, Pubmed, Web of Science, and Scopus published in the past few years to extract information on the topic.

Transmission Electron Microscopy of Protein Macromolecules

1971 ◽  
Vol 29 ◽  
pp. 424-425
Author(s):  
Henry S. Slayter
Keyword(s):  
Biological Systems ◽  
Metal Vapor ◽  
Resolving Power ◽  
Electron Microscopic ◽  
Chemical Methods ◽  
Molecular Weights ◽  
The Past ◽  
Physical Chemical ◽  
Transmission Electron

Electron microscopic methods have been applied increasingly during the past fifteen years, to problems in structural molecular biology. Used in conjunction with physical chemical methods and/or Fourier methods of analysis, they constitute powerful tools for determining sizes, shapes and modes of aggregation of biopolymers with molecular weights greater than 50, 000. However, the application of the e.m. to the determination of very fine structure approaching the limit of instrumental resolving power in biological systems has not been productive, due to various difficulties such as the destructive effects of dehydration, damage to the specimen by the electron beam, and lack of adequate and specific contrast. One of the most satisfactory methods for contrasting individual macromolecules involves the deposition of heavy metal vapor upon the specimen. We have investigated this process, and present here what we believe to be the more important considerations for optimizing it. Results of the application of these methods to several biological systems including muscle proteins, fibrinogen, ribosomes and chromatin will be discussed.

The Contribution of Phonon-Scattered Electrons to High-Resolution Electron Micrographs of Crystals

1990 ◽  
Vol 48 (1) ◽  
pp. 62-63
Author(s):  
H. Kohl
Keyword(s):  
High Resolution ◽  
Spherical Aberration ◽  
High Resolution Electron Microscopy ◽  
Static Potential ◽  
Qualitative Comparison ◽  
The Past ◽  
Resolution Electron ◽  
High Resolution Images ◽  
High Resolution Electron Micrographs ◽  
Extract Information

High-Resolution Electron Microscopy is able to determine structures of crystals and interfaces with a spatial resolution of somewhat less than 2 Å. As the image is strongly dependent on instrumental parameters, notably the defocus and the spherical aberration, the interpretation of micrographs necessitates a comparison with calculated images. Whereas one has often been content with a qualitative comparison of theory with experiment in the past, one is currently striving for quantitative procedures to extract information from the images [1,2]. For the calculations one starts by assuming a static potential, thus neglecting inelastic scattering processes.We shall confine the discussion to periodic specimens. All electrons, which have only been elastically scattered, are confined to very few directions, the Bragg spots. In-elastically scattered electrons, however, can be found in any direction. Therefore the influence of inelastic processes on the elastically (= Bragg) scattered electrons can be described as an attenuation [3]. For the calculation of high-resolution images this procedure would be correct only if we had an imaging energy filter capable of removing all phonon-scattered electrons. This is not realizable in practice. We are therefore forced to include the contribution of the phonon-scattered electrons.

Investigating Applicability of the Meshfree Method to the Structural Analysis of Tires

2012 ◽  
Vol 40 (2) ◽  
pp. 60-82
Author(s):  
Ken Ishihara ◽  
Takehiro Noda ◽  
Hiroyuki Sakurai
Keyword(s):  
Meshfree Method ◽  
Alternative Methods ◽  
The Finite Element Method ◽  
Tire Industry ◽  
Academic Communities ◽  
The Past ◽  
New Methodologies ◽  
Tire Modeling ◽  
Point Data ◽  
Conducting Research

ABSTRACT In contrast to the finite element method (FEM), which is widely used in the tire industry nowadays, some alternative methods have been proposed by academic communities over the past decade or so. The meshfree method is one of those new methodologies. Originally intended to remove the burden of creating the mesh that is inherent in FEM, the meshfree method relies on the point data rather than the mesh, which makes it much easier to discretize the geometry. In addition to those modeling issues, it has been found that the meshfree method has several advantages over FEM in handling geometrical nonlinearities, continuities, and so forth. In accordance with those emerging possibilities, the authors have been conducting research on the matter. This article describes the results of the authors' preliminary research on the applicability of the meshfree method to tire analyses, which include the theoretical outline, the strategy of tire modeling, numerical results, comparisons with results of FEM, and conclusions.

Statehood and the State-Like in International Law

2019 ◽  
Author(s):  
Rowan Nicholson
Keyword(s):  
Hong Kong ◽  
International Law ◽  
The State ◽  
Alternative Methods ◽  
Important Conclusion ◽  
Territorial Integrity ◽  
The Past ◽  
Imperial China ◽  
Peremptory Norms ◽  
Legal Sense

If the term were given its literal meaning, international law would be law between ‘nations’. It is often described instead as being primarily between states. But this conceals the diversity of the nations or state-like entities that have personality in international law or that have had it historically. This book reconceptualizes statehood by positioning it within that wider family of state-like entities. An important conclusion of the book is that states themselves have diverse legal underpinnings. Practice in cases such as Somalia and broader principles indicate that international law provides not one but two alternative methods of qualifying as a state: subject to exceptions connected with territorial integrity and peremptory norms, an entity can be a state either on the ground that it meets criteria of effectiveness or on the ground that it is recognized by all other states. Another conclusion is that states, in the strict legal sense in which the word is used today, have never been the only state-like entities with personality in international law. Others from the past and present include imperial China in the period when it was unreceptive to Western norms; pre-colonial African chiefdoms; ‘states-in-context’, an example of which may be Palestine, which have the attributes of statehood relative to states that recognize them; and entities such as Hong Kong.

scholarly journals A Theoretical Framework on the Determinants of Food Purchasing Behavior of the Elderly: A Bibliometric Review with Scientific Mapping in Web of Science

Foods ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 688
Author(s):  
Khaled Alhammadi ◽  
Luna Santos-Roldán ◽  
Luis Javier Cabeza-Ramírez
Keyword(s):  
Elderly Population ◽  
Web Of Science ◽  
The Elderly ◽  
Purchasing Behavior ◽  
Food Purchasing ◽  
The Past ◽  
Bibliometric Review ◽  
Food Market ◽  
The Common ◽  
Elderly Consumers

The past few years have seen significant demographic changes in most regions, including an increased elderly population. Subsequently, elderly citizens comprise an important market segment of consumers, with the food industry one of the most affected areas in this context. However, food market managers previously believed that elderly consumers’ needs were stereotyped in nature. The lack of focus on this sector, therefore, left elderly consumers as an untapped market, without realizing the financial independence of this segment regarding their nutrition. This research will attempt to provide the key determinant factors on elderly consumers’ behavior related to food. For that purpose, a complete literature review of more than 123 papers regarding these concepts has been carried out. Once analyzed, we highlight the common insights to give clear guidance for supermarket managers and food manufacturers to have a better knowledge of the reasons behind elderly people’s food acquisitions.

scholarly journals Viral hepatitis associated hepatocellular carcinoma on the African continent, the past, present, and future: a systematic review

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ottovon Bismark Dakurah ◽  
Cynthia Raissa Tchuem Tamandjou ◽  
Moleen Zunza ◽  
Wolfgang Preiser ◽  
Tongai Gibson Maponga
Keyword(s):  
Hepatocellular Carcinoma ◽  
Systematic Review ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Web Of Science ◽  
African Continent ◽  
Inclusion Criteria ◽  
Hepatitis D ◽  
The Past ◽  
B Virus

Abstract Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths in Africa. In Africa, the major causes of HCC include chronic infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV). Knowledge of the changes in the incidence of viral hepatitis-associated HCC over time and the factors responsible for such changes is key in informing policies for the prevention of viral hepatitis-associated HCC in Africa. Aim The study aimed to systematically summarize the changes in the prevalence of viral hepatitis among HCC patients and the overall effect of the prevalence of viral hepatitis on the incidence of HCC over the past four decades in Africa (1980–2019). Methods A literature search was conducted in MEDLINE (PubMed), Google Scholar, Science Direct, Scopus, Web of Science, and African wide web for articles published on viral hepatitis-associated HCC in Africa from 1980 to 2019. The abstracts of the articles were screened for eligibility and those meeting the inclusion criteria were retrieved and reviewed. Results A total of 272 studies were included in the analysis. Viral hepatitis-related HCC incidence changed by 1.17% (95% confidence interval (CI): 0.63–1.71, p < 0.001), 0.82% (95% CI: 0.45–1.18, p < 0.001), and 3.34% (95% CI: 2.44–4.25, p < 0.001) for every 1% change in the prevalence of HBV, HCV, and hepatitis D virus (HDV) respectively, per decade. The incidence of HBV-related HCC decreased by − 0.50% (95% CI: − 0.74 – − 0.25, p < 0.001) over the last 40 years, while HCV-related HCC increased. Conclusion Overall, the incidence of viral hepatitis-associated HCC has not declined, mainly due to no decline in the prevalence of HCV, HDV, and the high number of chronic hepatitis B carriers on the African continent. There is an urgent need for the allocation of resources for the implementation of treatment and preventive programs for HBV, HCV, HDV, and HCC in Africa. This systematic review is registered with PROSPERO®, number CRD42020169723.

scholarly journals Research on the Literature of Green Building Based on the Web of Science: A Scientometric Analysis in CiteSpace (2002–2018)

2019 ◽  
Vol 11 (13) ◽  
pp. 3716 ◽  
Author(s):  
Yingling Shi ◽  
Xinping Liu
Keyword(s):  
Web Of Science ◽  
Green Building ◽  
Development Trend ◽  
Status Quo ◽  
Future Research ◽  
Building Industry ◽  
Scientometric Analysis ◽  
The Past ◽  
Evolution Pattern ◽  
The Status

Since the 21st century, the concept of green building has been gradually popularized and implemented in more countries, which has become a popular direction in the area of sustainability in the building industry. Over the past few decades, many scholars and experts have done extensive research on green building. The purpose of this paper is to systematically analyze and visualize the status quo of green building. Therefore, based on Web of Science (WoS), this paper analyzed the existing knowledge system of green building using CiteSpace, identified keywords related to green building and their frequency of occurrence using the function of keyword co-occurrence analysis, recognized five clusters using the function of cluster analysis, and explored the knowledge evolution pattern of green building using citation bursts analysis in order to reveal how research related to green building has evolved over time. On the basis of aforementioned keywords, clusters, and citation bursts analysis, this paper has built a knowledge graph for green building. This paper can help readers to better understand the status quo and development trend of green building and to easier recognize the shortcomings in the development of green building, so as to provide a promising direction for future research.

scholarly journals The Clinical Utility of Virtual Reality in Neurorehabilitation: A Systematic Review

2018 ◽  
Vol 10 ◽  
pp. 117957351881354 ◽  
Author(s):  
Thais Massetti ◽  
Talita Dias da Silva ◽  
Tânia Brusque Crocetta ◽  
Regiani Guarnieri ◽  
Bruna Leal de Freitas ◽  
...  
Keyword(s):  
Systematic Review ◽  
Virtual Reality ◽  
Virtual Environments ◽  
Neurological Disorders ◽  
Clinical Utility ◽  
Spinal Cord Injuries ◽  
Web Of Science ◽  
The Past ◽  
Meta Analyses ◽  
The Impact

Background: Virtual reality (VR) experiences (through games and virtual environments) are increasingly being used in physical, cognitive, and psychological interventions. However, the impact of VR as an approach to rehabilitation is not fully understood, and its advantages over traditional rehabilitation techniques are yet to be established. Method: We present a systematic review which was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). During February and March of 2018, we conducted searches on PubMed (Medline), Virtual Health Library Search Portal databases (BVS), Web of Science (WOS), and Embase for all VR-related publications in the past 4 years (2015, 2016, 2017, and 2018). The keywords used in the search were “neurorehabilitation” AND “Virtual Reality” AND “devices.” Results: We summarize the literature which highlights that a range of effective VR approaches are available. Studies identified were conducted with poststroke patients, patients with cerebral palsy, spinal cord injuries, and other pathologies. Healthy populations have been used in the development and testing of VR approaches meant to be used in the future by people with neurological disorders. A range of benefits were associated with VR interventions, including improvement in motor functions, greater community participation, and improved psychological and cognitive function. Conclusions: The results from this review provide support for the use of VR as part of a neurorehabilitation program in maximizing recovery.

scholarly journals Historical discarding in Mediterranean fisheries: a fishers' perception

2015 ◽  
Vol 72 (9) ◽  
pp. 2600-2608 ◽  
Author(s):  
Dimitrios Damalas ◽  
Christos D. Maravelias ◽  
Giacomo C. Osio ◽  
Francesc Maynou ◽  
Mario Sbrana ◽  
...  
Keyword(s):  
Species Composition ◽  
Market Demand ◽  
Sampling Protocol ◽  
The Past ◽  
Regulatory Constraints ◽  
Fishing Strategies ◽  
Commercially Important ◽  
Trawl Fisheries ◽  
Important Fish

Abstract Discarding of commercially important fish species in the bottom trawl fisheries in the northern Mediterranean Sea was investigated by soliciting the long-term recollections of fishers engaged or formerly engaged in such fisheries. The main aim of our investigation was to describe the prevalence of discarding and its evolution over the past 70 years using information gathered through individual questionnaire-based interviews with fishers from ports in Spain, Italy, and Greece, following a standardized sampling protocol. Although it proved impossible to derive absolute estimates of the volume of discarded catches over the period investigated, we conclude that over the past 70 years, discarding as a practice has gradually increased in the northern Mediterranean trawl fisheries and has been accompanied by a shift in the species composition of the discarded catch. While discarding can occur for a number of reasons, our investigations indicate that discarding in the past was mostly driven by market demand, but recent legal and regulatory constraints have led to changes in fishing strategies and became a significant reason for discards.

Predation by Sharks on the Grey Seal (Halichoerus grypus) in Eastern Canada

1983 ◽  
Vol 40 (3) ◽  
pp. 267-271 ◽  
Author(s):  
Paul Brodie ◽  
Brian Beck
Keyword(s):  
Key Words ◽  
Population Size ◽  
Halichoerus Grypus ◽  
Longline Fishery ◽  
Grey Seal ◽  
Eastern Canada ◽  
The Past ◽  
Harbour Seals ◽  
Commercially Important ◽  
Important Fish

The increase in population size of the grey seal (Halichoerus grypus) off eastern Canada over the past 20 yr may be attributed to a decrease in shark stocks, their supposed predators. Reduction of the shark population is presumed to have resulted from a directed longline fishery and, of greater significance, from a change in the fishery for swordfish (Xiphias gladius) from selective harpooning to pelagic longlining, which has produced a large bycatch of sharks. The resulting enhanced survival of grey seals is reflected in greater infestation of commercially important fish species by the codworm (Phocanema decipiens).Key words: grey seals, harbour seals, sharks, swordfish, codworm, predation, fisheries

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