Risk factors and knowledge of the elderly people about chronic kidney disease

Background: In aging populations with an ever-growing burden of risk factors such as obesity, diabetes, and hypertension, chronic kidney disease (CKD) is on the rise. However, little is known about its exact prevalence among elderly adults, and often albuminuria is not included in the definition of CKD. Moreover, novel equations for the estimated glomerular filtration rate (eGFR) have recently emerged, which have not been applied comprehensively to older adults. Data on CKD awareness among the elderly are sparse. Objectives: To determine the prevalence of CKD among older adults by eGFR and albumin/creatinine ratio (ACR), compare the performance of 6 established and novel eGFR formulas, explore risk factors, and determine the awareness of CKD in a large cohort of community-dwelling elderly from Germany. Methods: A total of 1,628 subjects from the Berlin Aging Study II (BASE-II) were included in this analysis (mean age 68.7 years; 51.2% female). Extensive cross-sectional data on sociodemographics, lifestyle, medication, and diagnoses were inquired during structured interviews and a medical examination, and blood and urine parameters were measured. Results: In all, 77.1% of the subjects had hypertension, 12.4% had diabetes, and 18.3% were obese. The prevalence of CKD strongly depended on the eGFR equations used: 25.4% (full age spectrum [FAS] equation), 24.6% (Berlin Initiative Study), 23.1% (Lund-Malmö revised), 19.3% (Cockcroft-Gault), 16.4% (Chronic Kidney Disease-Epidemiology Collaboration [CKD-EPI]), and 14.7% (Modification of Diet in Renal Disease [MDRD]). Of the subjects with an eGFRFAS <60 mL/min/1.73 m2 and/or an ACR >30 mg/g, only 3.9% were aware of having CKD. Polypharmacy, age, BMI, coronary artery disease, non-HDL cholesterol, and female sex were independently associated with CKD. Conclusions: CKD is prevalent among older adults in Germany, but awareness is low. The FAS equation detects higher rates of CKD than MDRD and CKD-EPI, which are most widely used at present. Also, when CKD is defined based on eGFR and albuminuria, considerably more people are identified than by eGFR alone. Finally, polypharmacy is associated with an increased risk for CKD in the elderly.

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Faith and spirituality in the meaning of life of the elderly with Chronic Kidney Disease

Revista Brasileira de Enfermagem ◽

10.1590/0034-7167-2019-0323 ◽

2020 ◽

Vol 73 (suppl 3) ◽

Author(s):

Halanna Carneiro Gumarães Bastos Moura ◽

Tânia Maria de Oliva Menezes ◽

Raniele Araújo de Freitas ◽

Fabiana Araújo Moreira ◽

Isabella Batista Pires ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Qualitative Research ◽

Kidney Disease ◽

Elderly People ◽

Elderly Person ◽

Meaning Of Life ◽

The Elderly ◽

Existential Analysis ◽

Study Participants ◽

The City

ABSTRACT Objective: to understand faith and spirituality in the meaning of life of the elderly with Chronic Kidney Disease. Methods: a qualitative research based on Viktor Emil Frankl’s Logotherapy and Existential Analysis. Twenty elderly people were interviewed between August 2018 and January 2019, between 60 and 79 years old, who underwent dialysis in a private unit, a reference in nephrology in the city of Salvador, Bahia, Brazil. Results: two categories of analysis emerged: Meaning of faith in the lived of the elderly with Chronic Kidney Disease; Faith as a forerunner of the meaning of life. Final considerations: faith and spirituality were understood as a fundamental foundation in the search for the meaning of the study participants’ lives, besides unveiling itself as an important strategy of resilience to the experienced of the elderly person with Chronic Kidney Disease.

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Assessment of the frailty level of elderly people with chronic kidney disease undergoing hemodialysis

Acta Paulista de Enfermagem ◽

10.1590/1982-0194201400007 ◽

2014 ◽

Vol 27 (1) ◽

pp. 29-34 ◽

Cited By ~ 11

Author(s):

Fabiana de Souza Orlandi ◽

Gabriela Dutra Gesualdo

Keyword(s):

Chronic Kidney Disease ◽

Renal Replacement Therapy ◽

Kidney Disease ◽

Replacement Therapy ◽

Elderly People ◽

The Elderly ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional

OBJECTIVE: To assess the frailty level of elderly people with chronic kidney disease undergoing hemodialysis.METHODS: This is a cross-sectional study involving 60 participants and carried out at a Renal Replacement Therapy Unit. The Edmonton Frail Scale, translated and validated to Portuguese, was used as the instrument of research.RESULTS: Around 35.0% of the elderly showed no frailty, 26.7% were vulnerable, 20.0% showed mild frailty, 13.3% moderate frailty and 5.0% severe frailty.CONCLUSION: The frailty level of elderly people with chronic kidney disease undergoing hemodialysis was high and the number of elderly people who are vulnerable to frailty was also high.

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The Impact of Age on Mortality in Chronic Haemodialysis Popu-Lation with COVID-19

Journal of Clinical Medicine ◽

10.3390/jcm10143022 ◽

2021 ◽

Vol 10 (14) ◽

pp. 3022

Author(s):

Ander Vergara ◽

Mireia Molina-Van den Bosch ◽

Néstor Toapanta ◽

Andrés Villegas ◽

Luis Sánchez-Cámara ◽

...

Keyword(s):

Risk Factors ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Mortality Risk ◽

The Elderly ◽

Elderly Group ◽

High Risk Population ◽

Cox Regression Analysis ◽

Risk Of Death ◽

The Impact

Age and chronic kidney disease have been described as mortality risk factors for coronavirus disease 2019 (COVID-19). Currently, an important percentage of patients in haemodialysis are elderly. Herein, we investigated the impact of age on mortality among haemodialysis patients with COVID-19. Data was obtained from the Spanish COVID-19 chronic kidney disease (CKD) Working Group Registry. From 18 March 2020 to 27 August 2020, 930 patients on haemodialysis affected by COVID-19 were included in the Registry. A total of 254 patients were under 65 years old and 676 were 65 years or older (elderly group). Mortality was 25.1% higher (95% CI: 22.2–28.0%) in the elderly as compared to the non-elderly group. Death from COVID-19 was increased 6.2-fold in haemodialysis patients as compared to the mortality in the general population in a similar time frame. In the multivariate Cox regression analysis, age (hazard ratio (HR) 1.59, 95% CI: 1.31–1.93), dyspnea at presentation (HR 1.51, 95% CI: 1.11–2.04), pneumonia (HR 1.74, 95% CI: 1.10–2.73) and admission to hospital (HR 4.00, 95% CI: 1.83–8.70) were identified as independent mortality risk factors in the elderly haemodialysis population. Treatment with glucocorticoids reduced the risk of death (HR 0.68, 95% CI: 0.48–0.96). In conclusion, mortality is dramatically increased in elderly haemodialysis patients with COVID-19. Our results suggest that this high risk population should be prioritized in terms of protection and vaccination.

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Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph16224383 ◽

2019 ◽

Vol 16 (22) ◽

pp. 4383 ◽

Cited By ~ 2

Author(s):

Andong Ji ◽

Chunlei Pan ◽

Hongxia Wang ◽

Zhezhen Jin ◽

Joseph H. Lee ◽

...

Keyword(s):

Risk Factors ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Eastern China ◽

Public Health Problem ◽

The Elderly ◽

Cross Sectional Study ◽

Major Public Health Problem ◽

Cross Sectional ◽

Associated Risk Factors

Chronic kidney disease (CKD) is a global major public health problem. Almost all of previous studies evaluating the prevalence of CKD focused on adults, while studies among the elderly were relatively rare, especially in China. The aim of this study was to investigate the prevalence and associated risk factors of CKD among the elderly in Qingdao, China. This was a cross-sectional study with 38,038 inhabitants (aged 60–109) randomly recruited in Qingdao, China. All participants were required to complete a questionnaire for their demographic characteristics. Blood and urine samples of participants were collected, and the albumin and creatinine levels were measured for albuminuria and estimated glomerular filtration rate (eGFR) assessment. The associations between risk factors and indicators of kidney damage were analyzed by logistic regression. A total of 34,588 inhabitants completed the survey. The overall prevalence of CKD was 11.41% (95% confidence interval (CI): 11.07–11.74%) in the elders from Qingdao in 2016. The prevalence of albuminuria and low eGFR (<60 mL/min per 1·73 m²) were 8.47% (95% CI: 8.17–8.76%) and 3.98% (95% CI: 3.78–4.19%), respectively. Older age, hypertension, diabetes, anemia, hyperuricemia, hyperhomocysteinemia, hypertriglyceridemia, obesity, and LDL-C ≥ 4.1 mmol/L were independently associated with the presence of CKD. In conclusion, common chronic non-communicable diseases, including hypertension, diabetes, obesity, hyperhomocysteinemia, hyperuricemia, and hypertriglyceridemia, were associated with greater prevalence of CKD.

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Evaluation of risk factors that contribute to falls among the elderly

Revista Brasileira de Geriatria e Gerontologia ◽

10.1590/1981-22562017020.160022 ◽

2017 ◽

Vol 20 (1) ◽

pp. 56-66 ◽

Cited By ~ 1

Author(s):

Raquel Letícia Tavares Alves ◽

Carlos Fernando Moreira e Silva ◽

Luísa Negri Pimentel ◽

Isabela de Azevedo Costa ◽

Ana Cristina dos Santos Souza ◽

...

Keyword(s):

Risk Factors ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Activities Of Daily Living ◽

Daily Living ◽

The Elderly ◽

Minas Gerais ◽

The State ◽

Elderly Persons ◽

The City

Abstract Objective: to determine the incidence of falls among the elderly population of the city of Barbacena in the state of Minas Gerais, together with causal factors, circumstances and major consequences. Methods: a cross-sectional study was performed through questionnaires applied to 206 patients over the age of 60, from November 2014 to February 2015 in the city of Barbacena, in the state of Minas Gerais. Risk factors related to falls were analyzed, as well as the incidence of falls and the consequences for the lives of elderly persons. The existence of a relationship between the reporting of falls and possible risk factors was determined by the Chi-squared and Fischer's exact tests as indicated. Results: an incidence of falls of 36.41% was observed among the elderly, 45.95% of which occurred outside the home. A total of 85.71% of respondents had previously suffered strokes and 39.78% were taking medication. Among elderly persons who have fallen and suffered fractures (18.67%), 50% had suffered strokes, 50% were suffering from chronic kidney disease, and 61.54% could not perform their activities of daily living after the fall. Conclusion: it was concluded that the incidence of falls among the elderly was 36.41%, while the most correlated factors were drug use, stroke victims and people with chronic kidney disease. Among those who suffered fractures, 61.54% failed to perform activities of daily living. Preventing falls is a public health concern, and simple changes can reduce its prevalence.

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Insuficiência renal crônica: o impacto da hemodiálise na qualidade de vida do idoso / Chronic kidney disease: the impact of hemodialysis on the quality of life of the elderly people

Brazilian Journal of Health Review ◽

10.34119/bjhrv4n6-351 ◽

2021 ◽

Vol 4 (6) ◽

pp. 27998-28004

Author(s):

Maria Amélia Albuquerque de Freitas ◽

Julia Manuela Mendonça de Albuquerque ◽

Nicole Brandão Barbosa de Oliveira ◽

Isabelle Miranda Tavares ◽

Renata Chequeller de Almeida

Keyword(s):

Quality Of Life ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Elderly People ◽

The Elderly ◽

The Impact

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Fadiga em idosos submetidos ao tratamento hemodialítico

Revista Recien - Revista Científica de Enfermagem ◽

10.24276/rrecien2021.11.34.142-151 ◽

2021 ◽

Vol 11 (34) ◽

pp. 142-151

Author(s):

Isabel Pires Barra ◽

Marina De Góes Salvetti ◽

Viviane Peixoto dos Santos Pennafort ◽

Francisca Íris Araújo de Brito ◽

Maria Júlia Guimarães Oliveira Soares ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Elderly People ◽

Renal Dialysis ◽

The Elderly ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Nursing Team ◽

Relevant Finding

Identificar a ocorrência de fadiga em idosos com doença renal crônica em hemodiálise. Estudo descritivo, transversal e abordagem quantitativa, realizado de setembro a novembro de 2018 por meio da Escala de Fadiga de Piper-revisada. Participaram do estudo 45 idosos com idades entre 60 a 86 anos, 62,2% eram do sexo masculino. Identificou-se fadiga em 97,7% dos idosos e as causas atribuídas com maior frequência foram às sessões de hemodiálise (37,8%) e estresse (13,3%). Quanto aos fatores que promoveram alívio de fadiga, foram descritos descansar (53,3%), dormir (6,7%) e se alimentar (6,7%). A fadiga mostrou-se um achado relevante entre os idosos pesquisados, por isso merece a atenção da equipe de enfermagem para identificação e adequado manejo.Descritores: Diálise Renal, Idoso, Fadiga. Fatigue in elderly submitted to hemodialysis treatmentAbstract: To identify the occurrence of fatigue in the elderly with chronic kidney disease undergoing hemodialysis. A descriptive, cross-sectional study with a quantitative approach, carried out from September to November 2018 using the revised Piper Fatigue Scale. 45 elderly people aged 60 to 86 years participated on the study, 62.2% were male. Fatigue was identified in 97.7% of the elderly and the most frequently attributed causes were hemodialysis (37.8%) and stress (13.3%). As for the factors that promoted fatigue relief, rest (53.3%), sleep (6.7%) and eating (6.7%) were described. Fatigue proved to be a relevant finding among the elderly surveyed, which is why it deserves the attention of the nursing team for identification and adequate management.Descritores: Renal Dialysis, Age, Fatigue. Fatiga en personas mayores presentadas al tratamiento de hemodiálisisResumen: Identificar la aparición de fatiga en ancianos con enfermedad renal crónica en hemodiálisis. Un estudio descriptivo, transversal con un enfoque cuantitativo, llevado a cabo de septiembre a noviembre de 2018 utilizando la Escala de Fatiga Piper revisada. 45 personas mayores de 60 a 86 años participaron en el estudio, 62.2% eran hombres. La fatiga se identificó en el 97.7% de los ancianos y las causas más frecuentemente atribuidas fueron la hemodiálisis (37.8%) y el estrés (13.3%). En cuanto a los factores que promovieron el alivio de la fatiga, se describió el descanso (53.3%), el sueño (6.7%) y la alimentación (6.7%). La fatiga resultó ser un hallazgo relevante entre los ancianos encuestados, por lo que merece la atención del equipo de enfermería para su identificación y manejo adecuado.Descriptores: Diálisis Renal, Anciano, Fatiga.

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Epidemiology of Chronic Kidney Disease and Associated Metabolic Risk Factors in an Old Chinese Population

10.21203/rs.3.rs-107910/v1 ◽

2020 ◽

Author(s):

Lingling Xu ◽

Jin Liu ◽

Aiqin He ◽

Xiaomei Wu ◽

Dongling Li ◽

...

Keyword(s):

Risk Factors ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Elderly Population ◽

Metabolic Diseases ◽

Population Aging ◽

The Elderly ◽

Cross Sectional ◽

Chinese Elderly ◽

Independent Risk Factors

Abstract Chronic kidney disease (CKD) has become a worldwide health problem among aging populations. However, epidemiological information on Chinese elderly people with CKD is still lacking. This study aimed to investigate the epidemiological features and associated risk factors of CKD in aging population in China. In this cross-sectional study, a total of 37,533 individuals aged ≥65 years were enrolled in Binhai from January to December 2018. The crude and standardized prevalence of CKD were calculated. Associations of metabolism-related indicators with CKD were examined using univariate and multivariate analysis. The overall prevalence of CKD was 17.7% (95% confidence interval [CI], 17.3%-18.1%) in this Chinese elderly population. The prevalence was 17.5% among men (95% CI, 17.0%-18.1%) and 17.8% among women (95% CI, 17.3 -18.4%). The mean eGFR was 84.22 (SD ± 12.87) mL/min/1.73 m2, with the median value higher for women than for men. Aging, pre-HTN, HTN, elevated triglyceride and FBG were found to be independent risk factors for CKD. Our study shows a high prevalence of CKD among Chinese elderly population. Aging, pre-HTN, HTN, elevated triglyceride and FBG were all independent risk factors associated with CKD. More attention should be paid to metabolic diseases to prevent CKD in the elderly.

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Factors Associated with Mortality among Elderly People in the COVID-19 Pandemic (SARS-CoV-2): A Systematic Review and Meta-Analysis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18158008 ◽

2021 ◽

Vol 18 (15) ◽

pp. 8008

Author(s):

Vicente Paulo Alves ◽

Francine Golghetto Casemiro ◽

Bruno Gedeon de Araujo ◽

Marcos André de Souza Lima ◽

Rayssa Silva de Oliveira ◽

...

Keyword(s):

Systematic Review ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Elderly People ◽

Latin American ◽

Meta Analysis ◽

The Elderly ◽

Population Exposure ◽

Factors Associated ◽

Italian Studies

The objective of this meta-analysis was to evaluate the factors associated with the mortality of elderly Italians diagnosed with coronavirus who resided in institutions or who were hospitalized because of the disease. Methods: A systematic review following the recommendations of The Joanna Briggs Institute (JBI) was carried out, utilizing the PEO strategy, i.e., Population, Exposure and Outcome. In this case, the population was the elderly aged over 65 years old, the exposure referred to the SARS-CoV-2 pandemic and the outcome was mortality. The National Center for Biotechnology Information (NCBI/PubMed), Latin American and Caribbean Literature in Health Sciences (LILACS), Excerpta Medica Database (EMBASE) and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases were used until 31 July 2020. Results: Five Italian studies were included in this meta-analysis, with the number of elderly people included varying between 18 and 1591 patients. The main morbidities presented by the elderly in the studies were dementia, diabetes, chronic kidney disease and hypertension. Conclusions: The factors associated with the mortality of elderly Italian people diagnosed with SARS-CoV-2 who lived in institutions or who were hospitalized because of the disease were evaluated. It was found that dementia, diabetes, chronic kidney disease and hypertension were the main diagnosed diseases for mortality in elderly people with COVID-19.

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