scholarly journals Phytochemical and Antibacterial Screening on Leaf Extracts of Vitex negundo Linn

2011 ◽  
Vol 3 (7) ◽  
pp. 585-587
Author(s):  
P. Selvaganesh P. Selvaganesh ◽  
◽  
D. Nancy D. Nancy ◽  
D. Kamalnathan D. Kamalnathan
Keyword(s):  
Vitex Negundo ◽  
Leaf Extracts ◽  
Antibacterial Screening

scholarly journals LARVICIDAL ACTIVITY OF LANTANA INDICA AND VITEX NEGUNDO ON CULEX QUINQUEFASCIATUS

2018 ◽  
Vol 11 (5) ◽  
pp. 414
Author(s):  
Rathnasagar K ◽  
Thiyagaraj Anand
Keyword(s):  
Larvicidal Activity ◽  
Culex Quinquefasciatus ◽  
Binding Protein ◽  
Inhibitory Effect ◽  
Negative Control ◽  
Vitex Negundo ◽  
Leaf Extracts ◽  
Active Compounds ◽  
Sterol Binding

Objectives: The activity of two different leaf extracts of Lantana indica and Vitex negundo is tested against the 3rd and 4th instar Culex quinquefasciatus larvae to evaluate the potency of the extracts as a larvicide and to find an ecologically sustainable alternative to chemical insecticides. A bioinformatics screening approach was performed to evaluate the in vivo results.Methods: The obtained larvae’s from nearby water sources were tested with N, N-diethyl-meta-toluamide (DEET) as the positive control which is the commercial chemical mosquito repellent and the solvents used for the respective plant extracts act as the negative control. Petroleum ether (PE), ethyl acetate (EA) and an aqueous (AQ) extract were prepared for both L. indica and V. negundo extracts, and its larvicidal activity was tested. A docking based approach was used to study the inhibitory effect of known active compounds from L. indica and V. negundo against acetylcholine esterase (AChE) and sterol binding protein as targets.Results: On comparing the results between three plants extract for its larvicidal activity, the EA extract of V. negundo and L. indica is found to be potent with a low LC50 value. Further, the docking studies between active compounds of L. indica and V. negundo with AChE and Sterol binding protein as targets showed that the compound tangeritin-1 had a good docking score compared to DEET and could be a natural alternative for larvicidal activity in the mosquito.Conclusion: Individual activity of tangeritin-1 could be further studied with mosquito mortality studies and molecular simulations and develop tangeritin-1 as a potential larvicidal compound for commercial use.

Ovicidal and toxic effects of certain plant extracts to the castor semilooper, Achaea janata L. (Noctuidae: Lepidoptera)

2017 ◽  
Vol 51 (04) ◽  
Author(s):  
Ashwini A. Devarshi ◽  
S. R. Yankanchi
Keyword(s):  
Fourth Instar ◽  
Toxic Effects ◽  
Vitex Negundo ◽  
Ovicidal Activity ◽  
Leaf Extracts ◽  
Argemone Mexicana ◽  
Cent Mortality ◽  
Achaea Janata ◽  
Castor Semilooper ◽  
Ld50 Value

Ovicidal and toxic effects of crude leaf extracts of Clerodendrum inerme, Clerodendrum splendens, Clerodendrum multiflorum, Vitex negundo and Argemone mexicana were evaluated against the castor semilooper, Achaea janata L. (Noctuidae: Lepidoptera) using different bioassay methods. Among the extracts tested, the highest ovicidal activity was observed in C. splendens as well as A. mexicana with LD50 values of 7.65 and 9.14 mg-1, respectively. Leaf extracts of A. mexicana and C. inerme were toxic to both third and fourth instar larvae of A. janata through topical application. However, the extracts of A. mexicana and C. inerme found to be more toxic to third instar larvae with 70 and 73 per cent mortality, respectively. The lowest LD50 value of 5.33 mg-1 was recorded by A. mexicana extract and was followed by C. inerme extract with LD50 value of 7.26 mg-1. Present results indicated that A. mexicana and C. inerme plants have potential to use in IPM programme.

scholarly journals Studies on Analysis of Antioxidant and Enzyme Inhibitory Activity of Vitex negundo Linn.

2017 ◽  
Vol 9 (6) ◽  
Author(s):  
Ved Prakash ◽  
Shelly Rana ◽  
Anand Sagar
Keyword(s):  
Urease Activity ◽  
Therapeutic Potential ◽  
Radical Scavenging Activity ◽  
Scientific Evidence ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Vitex Negundo ◽  
Leaf Extracts ◽  
Treatment Of Obesity ◽  
Dpph Radical Scavenging

The current study was designed to investigate the leaf extracts of Vitex negundo Linn. for their antioxidant and enzyme inhibitory (α-amylae and urease) activity. The antioxidant capacity of the different extracts (methanol, acetone and aqueous) of this plant was evaluated by DPPH (1,1-diphenyl-2-picrylhydrazyl) and reducing power tests. The plant exhibited good DPPH radical scavenging activity and moderate reducing power potential Further, all the extracts of V. negundo were reported to possess good anti-alpha amylase and anti-urease activity of greater than 50% in all the solvents used at a concentration of 1 mg/mL. Thus the study provided scientific evidence to the traditional uses of this plant in the treatment of obesity, diabetes, ulcers, kidney stones etc. Therefore, the leaf extracts of this plant can be selected for further investigation to determine their therapeutic potential.

scholarly journals ANTI-CARIOGENIC POTENTIALS OF VITEX NEGUNDO LINN

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Savita Petwal ◽  
Madhuri Kaushish Lily ◽  
Gulshan Kumar Dhingra ◽  
Koushalya Dangwal
Keyword(s):  
Staphylococcus Aureus ◽  
Bacterial Pathogens ◽  
Lactobacillus Brevis ◽  
Total Phenolic ◽  
Vitex Negundo ◽  
Leaf Extracts ◽  
Bactericidal Effects ◽  
Ethanolic Extracts ◽  
Ic50 Values ◽  
Pharmacologically Active

Vitex negundo Linn. (Verbenaceae), is an ethnobotanical important shrub carrying a large array of pharmacologically active phytochemicals with diverse medicinal properties. Present study assessed the antibacterial activities of leaf and twig (without leaf) bioactives against common oral bacterial inhabitants viz., Staphylococcus aureus, Streptococcus oralis, Streptococcus gordonii, Streptococcus mutans, Lactobacillus brevis and Lactobacillus casei. Leaf and twig dried powdered samples of V. negundo were separately fractionated by five solvents in eluotropic series namely petroleum-ether, chloroform, absolute-ethanol, 80%-methanol and distilled-water. Extracts were further analyzed for total phenolic contents (TPC), flavonoids (TFC), tannins, alkaloids and terpenoids. Zone of inhibition, MIC, MBC and IC50 values of the fractionated extracts against oral bacterial pathogens were determined. The results demonstrated significantly higher antibacterial activity in ethanolic extracts (VnLEt) and chloroform (VnLCh) extracts of leaves as evident by their higher ZOI and lower MIC, MBC and IC50 values. VnLEt extracts showed bactericidal effects against all the tested six bacterial pathogens (L. casei>St. gordonii>Staphylococcus aureus>L. brevis>St. oralis=St. mutans). VnLCh showed notable bactericidal effects against five pathogens (L. casei>St. mutans>St. gordonii>Staphylococcus aureus) but remained ineffective against St. oralis and L. brevis. Among twig extracts, ethanolic extracts showed inhibition against Staphylococcus aureus, St. gordonii and St. mutans while chloroform extracts showed antibacterial effect only against Staphylococcus aureus. VnLEt extract showed abundance in TPC, TFC and tannins while VnLCh was rich in alkaloids and terpenoid suggesting their contribution in bactericidal effects against cariogenic bacterial pathogens. Hence, the present study successfully established V. negundo leaf extracts as an excellent natural remedy for oral-dental infections.

Preliminary Phytochemical Analysis and its Antimicrobial and Antioxidant Activitiy of Leaf Extract of Justicia Adhatoda

2021 ◽  
Vol 7 (4) ◽  
Keyword(s):  
Radical Scavenging ◽  
Antibacterial Properties ◽  
Ethanolic Extract ◽  
Diffusion Method ◽  
Phytochemical Analysis ◽  
Leaf Extracts ◽  
Antibacterial Study ◽  
Antibacterial Screening ◽  
Justicia Adhatoda

Justicia Adhatoda is one of the medicinal plant native to Asia that is widely used in antidiabetic, anti inflammatory, antibacterial properties, treatment of cough and other respiratory ailments. In the present study, few steps procedure method was used to extract the major compound in the leaves.From the leaf extracts, phytochemical tests, measurement of antioxidant activity andantibacterial activities were studied. The results showed that the ethanol leaf extracts contains Phenols, Flavonoids, Tannis, Alkaloids and Saponins. The antioxidant activitywas evaluated in-vitro by radical scavenging DPPH, FRAP and H2O2 method and the disc diffusion method was employed for the antibacterial study on Pseudomonas, Staphylococcus, Bacillus, E.coli using chloramphinicol antibiotic as standard. Antibacterial screening showed that the maximum zone of inhibition for ethanolic extract against E.Coli is around 1.35 cm.

Development and Evaluation of Herbal Mosquito Repellent Cream

2021 ◽  
pp. 6262-6268
Author(s):  
Bapan Banik ◽  
Jayanta Barman ◽  
Manash Pratim Dutta ◽  
Nikita Bhowmick
Keyword(s):  
Repellent Activity ◽  
Cross Resistance ◽  
Allergic Reactions ◽  
Vitex Negundo ◽  
Mosquito Repellent ◽  
Leaf Extracts ◽  
Development Of Resistance ◽  
Different Types ◽  
Safe Product

Mosquito repellent is a product that is applied to the skin or other surfaces to deter insects (and arthropods in general) from landing or climbing on that surface. The interest in plant-based repellants has been revived seeing that the development of resistance, cross-resistance and possible toxicity hazards associated with synthetic insecticides and their rising cost. The present study aimed towards the development and evaluation of safe and efficient herbal mosquito repellent from leaf extracts of Azadirachta indica, Vitex negundo, and Ocimum gratissimum. Six different types of formulation (Type-1 to 6) were prepared using each plant extract and optimized ingredients. The mosquito repellent activity of the formulation was tested using the arm-in-cage method. One skin rubbed with a small quantity of formulation was exposed to 20 mosquitoes and the number of mosquitoes that aligned or biting the arm was recorded in each minute for five minutes. The most effective repellent activity of the Type2 formulation was 87.5% (Y-shaped Model) and 91.62% (Rectangular-shaped Model). The Type1, Type3, Type4, Type5 and Type6 formulation showed 66.62% , 58.25%, 68.75%, 70.75% and 62.5% repellent activity in Y shaped model and 66.62%, 62.5%, 70.75%, 83.25% and 62.5% repellent activity in Rectangular shaped model respectively. During these studies, we found that Hexane extract showed higher repellent activity. No allergic reactions were observed upon the skin. So, it is a safe product. The formulation was ecological, economical and highly efficient.

Management of pigeonpea sterility mosaic disease

2016 ◽  
Author(s):  
E. Rajeswari ◽  
K. P. Smitha ◽  
A. Kamalakannan ◽  
D. Alice ◽  
JR. Kannan Bapu
Keyword(s):  
Field Experiments ◽  
Mosaic Disease ◽  
Field Conditions ◽  
Untreated Plot ◽  
Vitex Negundo ◽  
Leaf Extracts ◽  
Botanical Species ◽  
Population Reduction ◽  
Disease Reduction ◽  
Cent Disease

Field experiments were conducted to ascertain the efficacy of leaf extracts from botanical species viz., Vitex negundo (10%), Psoralea corylifola (10 %), Winter Green oil 30 EC (2%) against Sterility Mosaic Disease (SMD) in pigeonpea under field conditions. Resistant inducing chemicals viz., 200 ppm Salicylic acid and acaricides viz ; 0 .1% Fenazaquin and 0. 2% Dicofol were also evaluated against SMD. Comprehensive analysis of data demonstrated that the two sprays of 0.1% Fenazaquin first at 30 days after sowing and second at 15 days after first spray recorded the lowest (8.8 per cent) SMD incidence as compared to 46.1 per cent in untreated control which accounted for the disease reduction of 80.9 per cent. Among the plant products tested, winter green oil 30 EC (2 %) was effective by recording 19.0 per cent SMD incidence with 58.7 per cent disease reduction. Fenazaquin (0 .1%) spray reduced the mite (Aceria cajani) population by 81.9 per cent followed by winter green oil 30 EC (2 %) with the population reduction of 72.3 per cent. Fenazaquin (0 .1%) spray also influenced to record the highest yield of 815 kg per ha as against 492 kg per ha in untreated plot and therefore, 0.1% Fenazaquin could be the best alternative for the management of SMD in pigeonpea under field conditions.

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