HYPOGAMMAGLOBULINEMIA

PEDIATRICS ◽  
1960 ◽  
Vol 26 (5) ◽  
pp. 817-821
Author(s):  
Thomas F. Dolan ◽  
Norman B. McCullough ◽  
Lewis E. Gibson

An unusual patient, characterized by recurrent infections, hepatosplenomegaly, low levels of gamma-globulin in the serum (400 mg/100 ml) and lymphocytosis, is described. The patient had pneumonia due to Nocardia asteroides followed by chronic Salmonella newport infection of 16 months' duration, kept in check by continuous antibiotic therapy. No antibodies were produced against specific antigenic challenges. The relationship of this case to those of congenital and acquired agammaglobulinemia is discussed.

1977 ◽  
Vol 67 (3) ◽  
pp. 391-404 ◽  
Author(s):  
E. A. Bernays ◽  
R. F. Chapman ◽  
E. M. Leather ◽  
A. R. McCaffery ◽  
W. W. D. Modder

AbstractField and laboratory studies at Ibadan, Nigeria, showed that the young nymphs of Zonocerus variegatus (L.) normally reject cassava after biting it and die if they are confined on growing leaves. Later instars will eat cassava, especially when deprived of food for some time, but the adults progressively lose weight when restricted to feeding on growing cassava. On cut cassava, on the other hand, extensive feeding occurs and normal growth is maintained. The change from unpalatability to acceptability occurs within about an hour of cutting and is apparently associated with wilting. Cassava produces latex, but this was not distasteful to Zonocerus. The readiness to feed on growing cassava was associated with low levels of hydrogen cyanide production by the leaves; wilted leaves still produced hydrogen cyanide, but at a lower rate than turgid, growing leaves. In the area around Ibadan, Zonocerus regularly defoliates cassava in the latter part of the dry season, probably because a shortage of attractive foods forces the insect to eat cassava.


2005 ◽  
Vol 12 (4) ◽  
pp. 381-390 ◽  
Author(s):  
Mary C Corley ◽  
Ptlene Minick ◽  
R K Elswick ◽  
Mary Jacobs

This study examined the relationship between moral distress intensity, moral distress frequency and the ethical work environment, and explored the relationship of demographic characteristics to moral distress intensity and frequency. A group of 106 nurses from two large medical centers reported moderate levels of moral distress intensity, low levels of moral distress frequency, and a moderately positive ethical work environment. Moral distress intensity and ethical work environment were correlated with moral distress frequency. Age was negatively correlated with moral distress intensity, whereas being African American was related to higher levels of moral distress intensity. The ethical work environment predicted moral distress intensity. These results reveal a difference between moral distress intensity and frequency and the importance of the environment to moral distress intensity.


Sainteks ◽  
2020 ◽  
Vol 16 (2) ◽  
Author(s):  
S. Widyaningsih ◽  
A. Istifaraswati

The mental impact of cancer on patients is often severe. Patients who have been recently diagnosed with breast cancer tend to experience depression, emotional stress, disappointment, and even despair which later can damage their psychological well-being. This study aims to describe Psychological Well-being among breast cancer patients.134 breast cancer patients were recruited at the Out Patient Department (OPD) of Tugurejo Hospital Semarang city, Indonesia. The data were collected using Ryff Scale Psychological Well-being (RSPWB) questionnaire. Most of the respondents were middle-aged, married, unemployed and had been diagnosed with early stadium of breast cancer. Results showed approximately half of the total respondents (n=64%, 47.8%) experiencing low levels of psychological well-being over the entire period of the sickness. Among four subscales of psychological well-being, “positive relationship with others” subscale was reported to be very low among those respondents. However, almost two thirds of respondents perceived a higher degree of self-acceptance and life purpose while experiencing the illness. Nurses and healthcare providers need to be aware of the importance of counseling service and family/patients support group to improve the relationship of patients with others.Keywords: psychological well-being, breast cancer


1986 ◽  
Vol 64 (6) ◽  
pp. 528-534 ◽  
Author(s):  
A. M. Parissenti ◽  
M. B. Coukell

Optimal conditions for assaying and stabilizing the soluble cGMP-binding activity in Dictyostelium discoideum were established. Using these procedures, we investigated the relationship between the cGMP-binding activity and the cGMP-specific phosphodiesterase in this organism. In wild-type strains, the binding and phosphodiesterase activities were found to be regulated differently during development. Also, stmF mutants, which possess very low levels of cGMP-specific phosphodiesterase activity, exhibited normal levels of cGMP-binding activity. Fractionation studies revealed that the binding and phosphodiesterase activities could be resolved by DEAE-cellulose chromatography. Finally, the effect of pH on cGMP binding was different from that reported for cGMP-mediated activation of the phosphodiesterase. Taken together, these results indicate that the cGMP-binding protein and the cGMP-specific phosphodiesterase are probably unrelated. In addition, the cGMP-binding activity is not associated with cGMP-stimulated kinase activity and it does not elute from DEAE-cellulose like the highly conserved cGMP-dependent protein kinases found in other systems.


2018 ◽  
Vol 96 (7) ◽  
pp. 590-596 ◽  
Author(s):  
D. S. Fomina ◽  
T. N. Markova ◽  
V. V. Sadovskaya

The variety of tissue cells express receptors of vitamin D. The possible causative connection between lack of vitamin D and a number of inflammatory diseases such as bronchial asthma has stimulated interest in the potentially positive effects of vitamin D in the theraputic schemes. Conflicting data was demonstrated by numerous studies concerning the relationship of vitamin D and development of asthma . Most of them stress attention on the lack of studies with targeting population excluding subclasters and phenotypes of bronchial asthma, especially groups associated with low levels of vitamin D obesity, COPD and asthma, atopic patients. The question of prescribing of vitamin D in asthma, in the case of laboratory-proven deficiency or lack of vitamin D can be an option in therapy.


2020 ◽  
Vol 4 (1) ◽  
pp. 63-81
Author(s):  
Ganesh Bhattarai ◽  
Dhruba Raj Pokharel ◽  
Prem Bahadur Budathoki

 Large number of previous studies have tested that perception of organizational politics negatively impact on employee outcomes with linear relationship. To ascertain the condition where perception of organizational politics can be fruitful for employee outcomes, this study measured the nonlinear relationship of perception of organizational politics with satisfaction with co-workers and job stress. 453 employees working with microfinance companies in Kathmandu valley were surveyed to get cross sectional perceptual data. To infer the conclusion, data were analyzed adopting quantitative analysis, deductive reasoning approach as well as positivist research philosophy. Empirical evidences revealed the nonlinear impact of perception of organizational politics on satisfaction with co-workers and job stress. Both high and low levels of perceived organizational politics were harmful for satisfaction with co-workers and job stress. But a medium level of perception of organizational politics was fruitful for satisfaction with co-workers and job stress. The relationship between perception of organizational politics and satisfaction with co-workers was inverted U-shaped and the relationship between perception of organizational politics and job stress was U-shaped. Based on the findings, numbers of practical as well as theoretical implications are suggested.


Sainteks ◽  
2020 ◽  
Vol 16 (2) ◽  
Author(s):  
S. Widyaningsih ◽  
A. Istifaraswati

The mental impact of cancer on patients is often severe. Patients who have been recently diagnosed with breast cancer tend to experience depression, emotional stress, disappointment, and even despair which later can damage their psychological well-being. This study aims to describe Psychological Well-being among breast cancer patients.134 breast cancer patients were recruited at the Out Patient Department (OPD) of Tugurejo Hospital Semarang city, Indonesia. The data were collected using Ryff Scale Psychological Well-being (RSPWB) questionnaire. Most of the respondents were middle-aged, married, unemployed and had been diagnosed with early stadium of breast cancer. Results showed approximately half of the total respondents (n=64%, 47.8%) experiencing low levels of psychological well-being over the entire period of the sickness. Among four subscales of psychological well-being, “positive relationship with others” subscale was reported to be very low among those respondents. However, almost two thirds of respondents perceived a higher degree of self-acceptance and life purpose while experiencing the illness. Nurses and healthcare providers need to be aware of the importance of counseling service and family/patients support group to improve the relationship of patients with others.Keywords: psychological well-being, breast cancer


1994 ◽  
Vol 24 (8) ◽  
pp. 1646-1652 ◽  
Author(s):  
Peter S. Homann ◽  
Dale W. Cole ◽  
Helga Van Miegroet ◽  
Jana E. Compton

Concentrations of dissolved cations available for plant uptake and leaching are affected by many factors, including anion dynamics. To determine the relationship of dissolved cations to NO3−, soil solutions were sampled monthly with ceramic tension lysimeters for up to 8 years from O, A, and B horizons in mature red alder (Alnusrubra Bong.) and Douglas-fir (Pseudotsugamenziesii (Mirb.) Franco) stands. Concentrations of Ca, Mg, and K, but not Na, displayed greater temporal variation under red alder, where nitrification-produced NO3− varied considerably, than under Douglas-fir, where NO3− was near zero. In red alder soil solutions, Ca and Mg were strongly positively correlated with NO3− at all soil depths (r2 = 0.94–0.83; p < 0.000 01), while K and Na were not as strongly related to NO3− (r2 = 0.40–0.03; p = 0.0001 to > 0.2). In the B horizon, dissolved Ca and Mg paralleled the decrease in NO3− that occurred during the 4 years following harvest of red alder. In contrast, Ca and Mg were maintained at relatively high levels in the O and A horizons, possibly by increased levels of dissolved organic anions that partially offset the decline in anionic charge associated with the decrease in NO3−. In the O and A horizons following harvest, K was initially elevated but decreased to low levels during the following 4 years.


1972 ◽  
Vol 50 (3) ◽  
pp. 325-331 ◽  
Author(s):  
David L. Gibo

Population cages with Drosophila melanogaster and D. simulans in competition were maintained under high predation pressure. The cages were established under three different conditions. One group of cages was started with a large population (150 adults) of each species. In these cages D. melanogaster was quickly depressed to low levels by D. simulans. A second group of cages was established with a small population (15 adults) of each species. These cages showed a great deal of diversity of both population size and dominant species. The third group of cages was established by mixing the populations of the cages of the second group and redistributing this mixed population among separate cages. In this last group of cages, the D. simulans population resembled those observed in the cages started with large populations, but the D. melanogaster populations had changed. Instead of being depressed to extinction, D. melanogaster was observed to maintain an apparently stable population. Interspecific competition between the two species appeared to have been reduced. The relationship of these results to the founder effect, interdeme mixing, and rapid changes in competitive relationships is discussed.


1960 ◽  
Vol 13 (2) ◽  
pp. 118-123 ◽  
Author(s):  
J. C. Edozien ◽  
A. E. Boyo ◽  
D. C. Morley

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