ACIDOSIS IN PREMATURE INFANTS DUE TO LACTIC ACID

PEDIATRICS ◽  
1961 ◽  
Vol 27 (6) ◽  
pp. 921-930
Author(s):  
Herbert I. Goldman ◽  
Samuel Karelitz ◽  
Eli Seifter ◽  
Hedda Acs ◽  
Norman B. Schell
Keyword(s):  
Carbon Dioxide ◽  
Lactic Acid ◽  
Weight Gain ◽  
Premature Infants ◽  
Control Group ◽  
Carbon Dioxide Content ◽  
Appreciable Change ◽  
Skimmed Milk ◽  
Experimental Group ◽  
Poor Weight Gain

Sixteen premature infants were fed a proprietary lactic-acid milk preparation for 7 to 10 days and were compared to 16 control infants fed non-acidified half-skimmed milk. The experimental group gained less weight (6.5 gm/kg/day) than the controls (14.0 gm/kg/day). This poor weight gain in the experimental group was associated with the production of a metabolic acidosis, the average blood pH decreasing from 7.39 to 7.25, and the average carbon dioxide content in plasma decreasing from 19.6 to 14.8 meq/l. Corresponding averages in the control group showed no appreciable change. A similar study was carried out in six pairs of premature infants, with a formula of half-skimmed milk compared with the identical formula to which lactic acid was added. The results were similar to those in the first study with regard to the poor weight gain and decrease in carbon dioxide content in plasma of the infants fed the acidified milk. Addition of lactic acid to the feeding mixture was followed by a prompt increase in excretion of lactate in the urine, which corresponded to approximately 4% of the lactic acid fed. In four premature infants, 24-hour urine collections demonstrated an increase in excretion of sodium and ammonia, associated with the increased excretion of lactate. The increase in excretion of lactate is considered the major mechanism responsible for the observed acidosis. Studies with intravenous injection of racemic sodium lactate failed to show any deficiency in lactate metabolism in the premature infants. It is suggested that lactic-acid milks not be used for premature infants.

scholarly journals Research on the Influence of the Light and Sexing on Growth Performance and Slaughter Results at Young Quails from Mixed Baloteşti Population of Eggs-Meat

2017 ◽  
Vol 74 (1) ◽  
pp. 15
Author(s):  
Lucian IONITA ◽  
Elena POPESCU-MICLOSANU ◽  
George NICA ◽  
Cornel Octavian PANA
Keyword(s):  
Weight Gain ◽  
Growth Performance ◽  
Conversion Rate ◽  
Live Weight ◽  
Control Group ◽  
Average Weight ◽  
Feed Conversion ◽  
Feed Conversion Rate ◽  
Average Weight Gain ◽  
Experimental Group

The purposes of determining the influence of the light and sexing on growth performance and slaughter results atyoung quails from Balotesti population, was organized an experiment on 150 quails, betwen age of 28 and 70 days. The chicks were divided into two groups (control and experimental), and growth and slaughter performance were determined separately by sex. Have studied 2 lighting programs, a program of continous lighting with photoperiod duration of 16 hours (16 L + 8 N, control group) and a program with lighting with asymetric hours intervals with photoperiod duration of 16 hours (10L+2N+6L+6N, experimental group).Males and females from the experimental group were recorded average performance of growth high during the period 28 - 70 days. Live weight at age of 70 days was higher with 7.54 %, average weight gain was higher with 14.86 % and feed conversion rate was lower with 13.51 % at males from experimental group compared to males from the control group. Also, the live weight at the age of 70 days was higher with 18.09 %; average weight gain was higher with 35.12 %, while feed conversion rate was reduced with 30.08 % on females from the experimental group compared to females from the control group.The results of the slaughter at 70 days were superior in the caseof females from the both groups versus males. The average weight of the carcase was higher with 17.53 % in case of the females than that of males from the experimental group, and the carcase yield was 65.37 % at the females and 65.56 % for males. Also, the average weight of the carcase was higher with 5.08 % in case of females compared to that males from the control group, and the carcase yield was 64.20 % to females 66.70 % on males.Superior results recorded in the case of females and males from the experimental group recommended the program of lighting with asymmetric hours intervals in the growth of youth quail. Also, the higher slaughter results recorded in the case of females of the two groups recommended them in the meat production through a broiler of quail that combine advantages in the production of both males and females. 

scholarly journals Effect of supplemental pig milk replacer on piglet weight gain and sow backfat thickness

2015 ◽  
pp. 43-47
Author(s):  
Zsolt Győri ◽  
Péter Balogh ◽  
László Huzsvai ◽  
Gabriella Novotniné Dankó
Keyword(s):  
Weight Gain ◽  
Birth Weight ◽  
Environmental Factors ◽  
Milk Production ◽  
Milk Replacer ◽  
Control Group ◽  
Suckling Period ◽  
Liquid Milk ◽  
Period Data ◽  
Experimental Group

Sow milk production is the major factor limiting pig growth to weaning. Although the milk production of the sows incremental many environmental factors affect the actual performances. The supplemental milk replacer can be an appropriate solution to ward off disparities and try to equalize the available milk quantity to the piglets according to their appetite, to enlarge the weight of pigs at weaning, ultimately. The aim of the present study was to investigate the effects of liquid milk supplement on weight development and litter performance of the piglets during the suckling period. Data were collected from 60 farrowings, the weight of 649 piglets in a total were measured at birth, 14 days old and at weaning (28 days), respectively. In the control group (n=319) the piglets were suckled and got prestarter feed from day 10. In the experimental group (n= 330) the piglets had got liquid milk replacer in 10.71% solution, from day 10 after birth together with suckling and prestarter feed, as well. Based on the Duncan's multiple range tests, there were no significant differences in birth weight between the control and experimental group but we found significant differences between the 14 days weight and the weaning weight, subsequently. Based on the CV% of weight the experimental group became more homogenous, in contrary to the weight of the control group at the end of suckling period. The milk supplementation can be an appropriate solution to ward off disparities and to equalize the available milk quantity to the piglets according to their appetite, to enlarge and uniform the weight of pigs at weaning, ultimately.

A Controlled Clinical Trial of Local Anesthesia for Lumbar Punctures in Newborns

PEDIATRICS ◽  
1991 ◽  
Vol 88 (4) ◽  
pp. 663-669 ◽  
Author(s):  
Fran L. Porter ◽  
J. Philip Miller ◽  
F. Sessions Cole ◽  
Richard E. Marshall
Keyword(s):  
Carbon Dioxide ◽  
Clinical Trial ◽  
Heart Rate ◽  
Lumbar Puncture ◽  
Local Anesthesia ◽  
Subcutaneous Administration ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Transcutaneous Oxygen ◽  
Experimental Group

To evaluate the efficacy of subcutaneous administration of lidocaine for reducing physiologic instability in acutely ill newborns during clinically required procedures, 81 neonates who required lumbar punctures within the first month of life were stratified by birth weight and respiratory support and randomly assigned to an experimental or a control group. The experimental group received an injection of 0.1 mL/kg of 1% lidocaine prior to the lumbar puncture. The control group received a nonanesthetized lumbar puncture without placebo. Changes in heart rate, respiratory rate, transcutaneous oxygen and carbon dioxide tensions, and heart rate variability from baseline, preparatory (positioning/handling), lumbar puncture, and recovery periods were measured. The administration of lidocaine did not minimize physiologic instability in response to the lumbar puncture nor was it associated with any detectable adverse effects other than prolonging the duration of the lumbar puncture. Although significant physiologic changes were observed in response to preparatory procedures, few additional changes beyond those occurred in response to lumbar punctures in either the experimental or control group. It is concluded that local anesthesia failed to influence manifestations of physiologic instability during neonatal lumbar punctures and that preparatory procedures were more destabilizing than either the administration of lidocaine or the lumbar puncture itself. The results suggest that the management of newborns requires emphasis on minimizing the destabilizing effects of required and frequent handling procedures.

scholarly journals Fortification of maize meal improved the nutritional status of 1–3-year-old African children

2005 ◽  
Vol 8 (5) ◽  
pp. 461-467 ◽  
Author(s):  
Alufheli E Nesamvuni ◽  
Hester H Vorster ◽  
Barrie M Margetts ◽  
Annamarie Kruger
Keyword(s):  
Weight Gain ◽  
Vitamin A ◽  
Nutritional Status ◽  
Small Sample ◽  
Control Group ◽  
Serum Retinol ◽  
Positive Effects ◽  
African Children ◽  
Maize Meal ◽  
Experimental Group

AbstractObjectiveTo evaluate the effectiveness of a vitamin-fortified maize meal to improve the nutritional status of 1–3-year-old malnourished African children.DesignA randomised parallel intervention study was used in which 21 experimental children and their families received maize meal fortified with vitamin A, thiamine, riboflavin and pyridoxine, while 23 control children and their families received unfortified maize meal. The maize meal was provided for 12 months to replace the maize meal habitually consumed by these households.MethodsSixty undernourished African children with height-for-age or weight-for-age below the 5th percentile of the National Center for Health Statistics' criteria and aged 1–3 years were randomly assigned to an experimental or control group. Baseline measurements included demographic, socio-economic and dietary data, as well as height, weight, haemoglobin, haematocrit, serum retinol and retinol-binding protein (RBP). Anthropometric, blood and serum variables were measured again after 12 months of intervention. Complete baseline measurements were available for 44 children and end data for only 36. Changes in these variables from baseline to end within and between groups were assessed for significance with paired t-tests, t-tests and analysis of variances using the SPSS program, controlling for expected weight gain in this age group over 12 months. Relationships between changes in variables were examined by calculating correlation coefficients.ResultsThe children in the experimental group had a significantly (P≤0.05) higher increase in body weight than control children (4.6 kg vs. 2.0 kg) and both groups had significant (P≤0.05) but similar increases in height. The children in the experimental group showed non-significant increases in haemoglobin and serum retinol, while the control children had a significant (P = 0.007) decrease in RBP. The change in serum retinol showed a significant correlation with baseline retinol (P = 0.014), RBP (P = 0.007) and weight (P = 0.029), as well as with changes in haemoglobin (P = 0.029).ConclusionDespite a small sample size, this study showed positive effects of a vitamin-fortified maize meal on weight gain and some variables of vitamin A status in 1–3-year-old African children. The study confirmed the relationship between vitamin A and iron status. The results suggest that fortification of maize meal would be an effective strategy to address micronutrient deficiencies in small children in South Africa.

scholarly journals Zur N-reduzierten Fütterung von Mastschweinen bei Einsatz freier Aminosäuren

2000 ◽  
Vol 43 (2) ◽  
pp. 179-192
Author(s):  
H. Nonn ◽  
H. Jeroch
Keyword(s):  
Amino Acids ◽  
Body Weight ◽  
Weight Gain ◽  
Protein Content ◽  
Free Amino Acids ◽  
Free Amino ◽  
Crude Protein ◽  
Control Group ◽  
Experimental Group ◽  
Fattening Pigs

Abstract. Title of the Paper: Investigation on N-reduced feeding and use of free amino acids in fattening pigs The aim of the present study was to investigate the N-reduced feeding by fattening pigs feed by cereals rieh feedmixture supplemented with the free amino-acids L-lysine, DL-methionine, L-threonine, L-tryptophane, Lleucine, L-isoleucine, L-histidine and L-valine. It was to test extreme low crude protein content by requirement sufficient supply on amino-aeid. The reaction of the animals in growth, carcass quality and the reduction of Nexeretion was to investigate. The pigs were divided in two groups (control and experimental group) with 24 animals per group (12 females and 12 castrates). The experiment was divided into three periods (25–60, 60–85 and 85–110 kg body weight). The protein content of the feedmixture was by the control group 18.3, 15.6 and 13.6% and by the experimental group 14.0, 11.8 and 10.7%, respectively. The lysine-energy ratio of the feedmixture was by all three feeding periods by 0.72 or 0.74, 0.61 or 0.62 and 0.55 or 0.57 g lysine per MJ ME in control feedmixture or experimental feedmixture, respectively. By a high Performance are the average daily life weight gain (control group 869 and experimental group 863 g) and the lean meat rate (control group 55.2 and experimental group 55:0%) not influenced by the high of crude protein supply. The calculated N-excretion were by the control group 4.16 kg (as 100%) and by experimental group 2.60 kg (62.5%) per 100 kg body weight gain.

scholarly journals Effects of a Community-based Follow-up Program for Parents with Premature Infants on Parenting Stress, Parenting Efficacy, and Coping

2020 ◽  
Vol 26 (3) ◽  
pp. 366-375
Author(s):  
Eun Sun Ji ◽  
Ka Ka Shim
Keyword(s):  
Parenting Stress ◽  
Premature Infants ◽  
Coping Behavior ◽  
Home Visits ◽  
Control Group ◽  
Community Based ◽  
Parenting Efficacy ◽  
And Coping ◽  
Experimental Group

Purpose: This study was conducted to evaluate the efficacy of a community-based follow-up program on parenting stress, parenting efficacy, and coping among parents with premature infants.Methods: A non-equivalent control group pre-post quasi-experimental design was used. This program consisted of structured home visits and self-help group meetings for 6 months. The experimental group (n=29) received visits by an experienced neonatal intensive care unit (NICU) nurse and the control group (n=27) was visited by a visiting nurse. Data were analyzed using the <i>x</i><sup>2</sup> test, t-test, and analysis of covariance.Results: Parents' coping behavior significantly differed in the experimental group compared to the control group (t=3.14, <i>p</i>=.003). In particular, coping subscale I, for maintaining the family situation (t=2.63, <i>p</i>=.011), and subscale III, for understanding the infant's medical situation (t=4.30, <i>p</i><.001), showed significant differences in the experimental group. There were no significant between-group differences in parenting stress or parenting efficacy.Conclusion: The findings of this study suggest that home visits by an experienced NICU nurse provided through a community-based follow-up program were an effective intervention to improve coping behavior among parents with premature infants.

scholarly journals THE EFFECT OF BISOLBI ON BIOCHEMICAL AND PRODUCTIVE PROCESSES OF THE HOLSTEIN-FRIESIAN CALVES

2021 ◽  
Vol 6 (1) ◽  
pp. 57-63
Author(s):  
Galina Molyanova ◽  
Maksim Nogotkov
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Average Daily Gain ◽  
The Body ◽  
Daily Weight Gain ◽  
Control Group ◽  
Average Daily Weight Gain ◽  
Glucose Content ◽  
Holstein Friesian ◽  
Experimental Group

The purpose of the research is increasing the average daily gain of animals due to the use of the Bisolbi drug. The effect of Bisolbi preparation based on Bacillus subtilis H-13 1.5×108 (LLC «Bisolbi-Inter») on the biochemical and productive life of calves was studied. The scientific and production experiment was carried out on the basis of a dairy farm of the State «Kupinskoe» Unitary Enterprise of the Samara region involving 30 Holstein-Friesian calves. The biological effect of the drug is provided due to its adsorption properties, the ability to enhance the activity of a number of enzyme systems and increase the digestive and systemic immunity of the body. The drug use increases the integration intensity of animals: the amount of total protein in the blood serum of calves of the experimental group at 120 days of age was higher by 8.9% (p<0.05), albumin – by 9.2% (p<0.01), compared with the animal data of con-trolled group. The Bisolbi indication contributed to an increase in the intensity of carbohydrate-lipoid metabolism: the cholesterol amount was higher by 23% (p<0.01), the glucose content – by 0.4 mmol/l (p<0.05) in the blood of 120 day old calves of the experimental group, compared with the data of controlled animals. It was found that the body weight of calves in the control group of 100 days age was 105.23±2.11 kg, in the experimental group – 108.6±2.19 kg, which is 3.37 kg higher. The average daily weight gain of animals in experimental group was signif-icantly higher by 0.075 kg (p<0.01). At 120 days of age, the body weight of the experimental calves was higher by 4.19 kg (p<0.05), the average daily weight gain by 0.080 kg (p<0.05), compared with the data of the controlled ani-mals. The indication of Bisolbi 5-10 ml (LLC «Bisolbi-Inter») to calves daily for 2 months resulted in an additional profit constructively of 137 rubles from each head.

scholarly journals The effect of multisensory stimulation on weight gain in premature infants admitted to the intensive care unit: A clinical trial study

2021 ◽  
Vol 20 (1) ◽  
pp. 96-102
Author(s):  
Sari Mahdieh ◽  
◽  
Mozhgan Rahnama ◽  
Fereshteh Ghaljaei ◽  
Majid Reza Akbarizadeh ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Weight Gain ◽  
Preterm Infants ◽  
Premature Infants ◽  
Infant Nutrition ◽  
Visual Stimulation ◽  
T Test ◽  
Control Group ◽  
Multisensory Stimulation

Introduction. Premature infants undergo a lot of stressful procedures during care and treatment procedure, which may lead to weight changes. Multisensory stimulation is a broad classification of interventions designed to improve the developmental and physiological outcomes of preterm infants admitted to the neonatal intensive care unit (NICU). The aim of this study was to evaluate the effect of multisensory stimuli on weight gain in preterm infants admitted to the NICU. Materials and methods. This study was a two-group randomized controlled trial (multisensory stimulation and control group). Forty preterm infants admitted to the NICU who met the inclusion criteria were selected. The intervention method was a multisensory stimulation program including auditory stimulation, tactile stimulation, visual stimulation and vestibular stimulation, which were performed by the researcher for 12 min (each stimulation lasting for 3 min). The infant nutrition was monitored and recorded during the intervention and the infant’s weight was measured after changing diapers every morning for a 7 days. It was conducted in the two groups using a calibrated scale of confirmed validity and reliability. Data were analyzed using SPSS 20 software, paired t-test and independent t-test. Results. Based on the findings of the present study, an upturn was observed in weight gain of preterm infants as a result of multisensory intervention. This indicates that the intervention improves weight gain in premature infants. Conclusions. Since premature infants are usually hospitalized in the NICU for a long time due to their low weight and poor physical condition, they are mostly cared by nurses. Hence, considering its positive outcomes, besides specialized care, this effective and very low cost method could be used by nurses to promote weight gain and early discharge of preterm infants.

scholarly journals Effects of a Breastfeeding Support Program on the Prevalence of Exclusive Breastfeeding and Growth in Late Preterm Infants

2020 ◽  
Vol 26 (1) ◽  
pp. 90-97 ◽  
Author(s):  
Gun Ja Jang ◽  
Yeon Ran Hong
Keyword(s):  
Weight Gain ◽  
Preterm Infants ◽  
Exclusive Breastfeeding ◽  
Support Program ◽  
Late Preterm ◽  
Control Group ◽  
Breastfeeding Support ◽  
Late Preterm Infants ◽  
Feeding Type ◽  
Experimental Group

Purpose: The purpose of this study was to investigate the effects of a breastfeeding support program (BSP) on the prevalence of exclusive breastfeeding and growth in late-preterm infants.Methods: A quasi-experimental study was conducted. The participants were 40 late preterm infants (LPIs), of whom 20 were assigned to the experimental group and 20 to the control group. For the mothers in the experimental group, a BSP was provided prior to the LPIs’ discharge and reinforced once a week for 4 weeks. Information on the feeding type was collected by observation and the LPIs’ body weight was measured.Results: There were significant differences in feeding type by group and time. Exclusive breastfeeding was 5.18 times more common in the experimental group than in the control group (odds ratio=5.18, 95% confidence interval=1.11~16.70). However, weekly weight gain did not show a significant relationship with group and time (F=0.40, <i>p</i>=.712).Conclusion: The BSP was helpful for increasing the rate of exclusive breastfeeding in LPIs. Furthermore, the LPIs in the experimental group, which had a higher likelihood of being exclusively breastfed, showed an equivalent amount of weight gain as the LPIs in the control group, in which infants were more likely to be formula-fed.

scholarly journals MORPHO-BIOCHEMICAL AND PRODUCTIVE INDICATORS OF DUCK-BROILERS WHEN USING PROBIOTIC "LACTOBIFADOL"

2021 ◽  
Vol 248 (4) ◽  
pp. 254-260
Author(s):  
A.F. Khabirov ◽  
◽  
Keyword(s):  
Weight Gain ◽  
Live Weight ◽  
Feed Consumption ◽  
Control Group ◽  
Live Weight Gain ◽  
Positive Effect ◽  
Experimental Group ◽  
Average Consumption

The reaction of the organism of broiler ducklings to the introduction of the probiotic additive "Lactobifadol" into the organism when reared up to 7 weeks of age was investigated. A positive effect was achieved to increase the live weight of the experimental poultry by 5.0 % (p <0.5), the average feed consumption per 1 kg of live weight gain in the group of broiler ducklings fed with Lactobifadol feed was 4.7 % less when compared to intact poultry. The dynamics of feed consumption per 1 kg of live weight gain in the first three weeks of rearing was descending, and from 4 weeks of age until the end of rearing, fodder consumption increased significantly. For 6 weeks of growing, the average consumption of compound feed per head per day in the control group of broiler ducklings was 157.5 g, in the experimental group – 158.5 g per 1 bird/day. The inclusion of "Lactobifadol" in the diet to a certain extent stimulates the processes of erythrocytopoiesis, providing, within the physiological norm, an increase in the level of hemoglobin and the number of leukocytes.

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