Controlled Evaluation of Muscle Relaxation in the Ventilated Neonate

PEDIATRICS ◽  
1981 ◽  
Vol 67 (5) ◽  
pp. 641-646
Author(s):  
N. N. Finer ◽  
P. M. Tomney

To assess the effects of muscle relaxation on the critically ill ventilated neonate, pancuronium bromide was administered for a 12-hour period to ten low-birth-weight neonates (960 to 2,000 gm) of 26 to 34 weeks gestation, all of whom required mechanical ventilation and were studied within 48 hours of birth (six to 39 hours). The infants were also studied for a 12-hour period during which no pancuronium bromide was administered. During both study periods, the order of which was randomized, heart rate, blood pressure, Po2, and intracranial pressure were continuously measured. The amounts of handling during the pancuronium and control periods were similar. The results revealed a significantly greater duration of hypoxia (P02 < 50 torr) (56.1 vs 23.6 minutes, P < .001) and hyperoxia (Po2 > 70 torr) during the control period (92.5 vs 13 minutes, P < .001). Durations of intracranial pressure elevation 10 cm H2O above the infant's baseline were significantly less during paralysis (6.7 vs 58.8 minutes, P < .001) as were spikes of intracranial pressure to greater than 25 cm H2O (1.6 vs 24.4, P < .05). There was no significant improvement in blood gas values, fractional inspiratory oxygen, or ventilator settings during muscle relaxation. Pancuronium reduced periods of nonoptimal oxygenation and elevated intracranial pressure and may therefore help to decrease adverse sequelae for the low-birth-weight, ventilated neonate.

Jurnal NERS ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. 111
Author(s):  
Desriati Devi ◽  
Yeni Rustina ◽  
Defi Efendi

Introduction: Low birth weight (LBW) infants who have been hospitalized are exposed to various conditions that provoke discomfort, which could trigger a stress response and growth disorders. This study aimed to identify the effects of auditory stimuli from Murottal Quran when it comes to the comfort and weight of LBW infants.Methods: This study used a clinical randomized controlled trial design involving 52 low birth weight infants. The infants were randomly assigned to either the intervention group (n=26) or the control (n=26). The intervention of Murottal Quran was given using a speaker 4 times a day for 20 minutes every 3 hours. This intervention was conducted for three days.Results: The results of this study show that there is a significant difference in the comfort of  low birth weight infants after Murottal Qur’an on the first, second, and third days between the intervention and control groups (p=0.014; <0.001; <0.001). There was no significant difference in the weight between the intervention and control groups in the first, second, and third days (p=0.481; 0.481; 0.464).Conclusion: The auditory stimuli of Murottal Quran can help to improve the comfort level of low birth weight infants during hospitalization. It can therefore be used as a supportive therapy to facilitate low birth weight infant and premature infant development.


2019 ◽  
Vol 7 (2) ◽  
pp. 74-84
Author(s):  
Mita Maulida Rifqiya Faiza ◽  
Novia Fransiska Ngo ◽  
Ika Fikriah

Preeclampsia defined as new onset of hypertension and proteinuria after 20 weeks of gestation. Preeclampsia is one of the three main causes of maternal mortality with an incidence of 128,273 each year or around 5.3% in Indonesia. Preeclampsia is classified as preeclampsia without severe features and severe preeclampsia. Severe preeclampsia can be a problem, both in the mother and the fetus due to vascular vasospasm. If uteroplacental blood flow to the fetus is limited, the fetus can be born under low birth weight (LBW), preterm birth, intra uterine fetal death, and low Apgar score. The aim of this research is to determine the correlation of severe preeclampsia with fetal complication, that is intra uterine fetal death (IUFD), preterm labor, neonatal asphyxia, and low birth weight (LBW). The design of this research is case control study with 46 sample for both case and control groups. The data analysis used chi-square for 2x2 table and likelihood ratio for 2x3 table. The results of this this research is showed that there was correlation between severe preeclampsia with preterm labor (p=0,000)and severe preeclampsia with low birth weight (p=0,000), there was no correlation between severe preeclampsia with IUFD (p=0,822) and severe preeclampsia with neonatal asphyxia (p=0,060)


Author(s):  
W. A. Tweed ◽  
Jørn Overgaard

SUMMARY:The object of this study was to determine if traumatic brain edema (BE) and increased intracranial pressure (ICP) reduce cerebral blood flow (CBF). Two groups of patients were studied, one with slight BE and ICP less than 20 mm Hg., the other with pronounced BE and ICP over 20 mm Hg. Although ICP was higher and cerebral perfusion pressure lower in pro-nounced edema there was only a small and non-significant reduction in CBF and no difference in cerebro-vascular resistance. Since traumatic BE does not increase resistance to blood flow through the brain, cerebral perfusion can be maintained if an adequate perfusion pressure is established. This in turn, demands the monitoring and control of ICP.


2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Nneka U. Igboeli ◽  
Maxwell O. Adibe ◽  
Chinwe V. Ukwe ◽  
Nze C. Aguwa

Background. In 2005, Nigeria changed its policy on prevention of malaria in pregnancy to intermittent preventive treatment with sulphadoxine-pyrimethamine (IPTp-SP). Indicators of impact of effective prevention and control of malaria on pregnancy (MIP) are low birth weight (LBW) and maternal anaemia by parity. This study determined the prevalence of LBW for different gravidity groups during periods of pre- and postpolicy change to IPTp-SP. Methods. Eleven-year data were abstracted from the delivery registers of two hospitals. Study outcomes calculated for both pre- (2000–2004) and post-IPTp-SP-policy (2005–2010) years were prevalence of LBW for different gravidity groups and risk of LBW in primigravidae compared to multigravidae. Results. Out of the 11,496 singleton deliveries recorded within the 11-year period, the prevalence of LBW was significantly higher in primigravidae than in multigravidae for both prepolicy (6.3% versus 4%) and postpolicy (8.6% versus 5.1%) years. The risk of LBW in primigravidae compared to multigravidae increased from 1.62 (1.17–2.23) in the prepolicy years to 1.74 (1.436–2.13) during the postpolicy years. Conclusion. The study demonstrated that both the prevalence and risk of LBW remained significantly higher in primigravidae even after the change in policy to IPTp-SP.


2020 ◽  
Vol 9 (8) ◽  
pp. e692986538
Author(s):  
Priscilla Perez da Silva Pereira ◽  
Ana Claudia Morais Godoy Figueiredo ◽  
Fabiana Araújo Figueiredo da Mata ◽  
Roberta Borges Silva ◽  
Mauricio Gomes Pereira ◽  
...  

The birth weight of newborn is an indicator that reflects maternal health conditions and the healthcare quality delivered during pregnancy. The aim of this study is to analyze the association between maternal consumption of cigarette during pregnancy and Low Birth Weight (LBW) in the Northeast of Brazil. Case-control study with the group of cases composed of 402 mothers with newborns with a birth weight <2,500 grams, and control composed of 1,210 mothers with newborns with weight ≥2,500 grams. Data were collected based on self-reported information by mothers and complemented with hospital records. Simple linear regression and logistic regression models were conducted. Majority of women were brown/ black, married, of low income and almost half of them had less than nine years of education. The consumption of 10 or more cigarettes a day was associated with LBW. For each cigarette added to the daily cigarette consumption there was a reduction of 18.6 grams in birth weight. Among mothers who smoked more than ten cigarettes per day, the mean reduction in birth weight was 283.1 grams. This study reinforces that LBW is associated with the maternal consumption of cigarettes.


Jurnal NERS ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. 111
Author(s):  
Desriati Devi ◽  
Yeni Rustina ◽  
Defi Efendi

Introduction: Low birth weight (LBW) infants who have been hospitalized are exposed to various conditions that provoke discomfort, which could trigger a stress response and growth disorders. This study aimed to identify the effects of auditory stimuli from Murottal Quran when it comes to the comfort and weight of LBW infants.Methods: This study used a clinical randomized controlled trial design involving 52 low birth weight infants. The infants were randomly assigned to either the intervention group (n=26) or the control (n=26). The intervention of Murottal Quran was given using a speaker 4 times a day for 20 minutes every 3 hours. This intervention was conducted for three days.Results: The results of this study show that there is a significant difference in the comfort of  low birth weight infants after Murottal Qur’an on the first, second, and third days between the intervention and control groups (p=0.014; <0.001; <0.001). There was no significant difference in the weight between the intervention and control groups in the first, second, and third days (p=0.481; 0.481; 0.464).Conclusion: The auditory stimuli of Murottal Quran can help to improve the comfort level of low birth weight infants during hospitalization. It can therefore be used as a supportive therapy to facilitate low birth weight infant and premature infant development.


2015 ◽  
Vol 4 (1) ◽  
pp. 30-34 ◽  
Author(s):  
Kashif Shahnawaz ◽  
Sanjay Kumar Choudhary ◽  
Gautam Sarker ◽  
Palash Das ◽  
Ranabir Pal ◽  
...  

Low birth weight (LBW) is an important cause of perinatal, neonatal and post-natal morbidity and mortality. In developing countries, LBW of newborns is mainly due to the poor socio-economic and environmental conditions of the mother. The aim of the study was to identify and quantify the effects of age, religion, socio-economic status and occupation of mothers, in order to examine which factors were primarily responsible for LBW of babies. In this study, all singleton newborn having a weight of <2.5kg was included as a case and a weight of ?2.5kg was included as a control. The relation of birth-weight to few maternal factors such as age, socio-economic status, religion and occupation were studied. A total of 120 cases and 240 controls were selected. After selection of each case as defined, the next available two newborns that had fulfilled the criteria for controls given above were selected and included in the control group. This ensured a case:control ratio of 1:2. Our Study showed that the greatest number of mothers having LBW newborns were in the age group of 21 to 25 years (50% and 45.1% in both the cases and control groups respectively), belonged to socio-economic group V (42.5% and 40% in both groups respectively) and were Hindus (96.7% and 89.6% in both groups respectively). It was found that 70% of LBW babies were born to mothers who belonged to the labor class by occupation. This study concluded with the findings that maternal factors like age, socio-economic status, religion and occupation of the mothers were related to LBW of the newborns. Avoiding teenage pregnancies, improving the socio-economic status (SES) of people and providing better workingDOI: http://dx.doi.org/10.3329/seajph.v4i1.21836 South East Asia Journal of Public Health Vol.4(1) 2014: 30-34


Author(s):  
Nita Hestiyana ◽  
Fakhruddin Razy

Latar belakang: Hipertensi pada persalinan mempengaruhi 10% semua wanita bersalin diseluruh dunia dan merupakan penyebab penting morbiditas akut berat. Hipertensi pada ibu hamil dapat berlanjut sampai ke masa persalinan yang mengakibatkan gangguan pertumbuhan janin intrauterin yang tentunya akan berdampak terhadap berat badan lahir sehingga pada ibu dengan tekanan darah tinggi akan lebih tinggi kemungkinan melahirkan dengan BBLR. Data RSUD Dr. H. Moch. Ansari Saleh Banjarmasin menyatakan tahun 2017 sebanyak 344 orang (11,1%) yang menderita hipertensi dan sebanyak 223 bayi (33,33%) mengalami BBLR.Tujuan: Mengetahui Korelasi Hipertensi Pada Persalinan dengan Kejadian Bayi Berat Lahir Rendah (BBLR) di RSUD Dr. H. Moch. Ansari Saleh Banjarmasin.Metode: Penelitian ini menggunakan pendekatan case control. Sampel penelitian menggunakan rasio 1:1 yaitu kasus (BBLR) sebanyak 223 dengan menggunakan teknik pengambilan sampel total sampling dan kontrol (tidak BBLR) sebanyak 223 dengan menggunakan sytematic random sampling. Penelitian ini menggunakan uji chi square.Hasil: Terdapat  korelasi antara hipertensi pada persalinan dengan kejadian bayi berat lahir rendah (BBLR) di RSUD Dr. H. Moch Ansari Saleh Banjarmasin. Nilai OR 3.027 yang berarti ibu bersalin dengan hipertensi berpeluang 3 kali mengalami BBLR dibandingkan dengan ibu yang tidak hipertensi.Simpulan: Hasil analisis menunjukkan ada korelasi antara hipertensi pada ibu bersalin dengan kejadian bayi berat lahir rendah (BBLR) di ruang VK.Kata kunci :bayi berat lahir rendah, hipertensi, persalinan Hypertension Correlation in Labor With the incidence of Low Birth Weight Babies (LBWB)in RSUD DR. H. Moch Anshari Saleh Banjarmasin  Abstract Background: Labor hypertension affects 10% of all maternity women worldwide and is an important cause of severe acute morbidity. Hypertension in pregnant women can continue into labor, which results in intrauterine fetal growth disorders which of course will have an impact on birth weight so that women with high blood pressure will be more likely to give birth with LBW. Data from Dr. H. Moch. Ansari Saleh Banjarmasin stated that in 2017 there were 344 people (11.1%) who suffered from hypertension and as many as 223 babies (33.33%) had LBW.Objective: To determine the correlation of hypertension in childbirth with the incidence of low birth weight babies at the Dr. H. Moch. Ansari Saleh Banjarmasin.Method: This study uses a case control approach. The study sample used a ratio of 1: 1, namely case (LBW) as much as 223 by using a total sampling and control sampling technique (not LBW) of 223 by using systematic random sampling. This study used the chi square test.Results: There was a correlation between labor hypertension and the incidence of low birth weight (LBW) in Dr. Hospital. H. Moch Ansari Saleh Banjarmasin. OR value of 3,027 which means that mothers giving birth with hypertension have a 3 times chance of having low birth weight compared to mothers without hypertension.Conclusion: The results of the analysis show that there is a correlation between hypertension in maternity and the incidence of low birth weight babies in the VK room. Keywords: low birth weight babies, hypertension, labor


2019 ◽  
Vol 1 (3) ◽  
pp. 16
Author(s):  
Safaa S. Ahmed ◽  
Sahar S. Faheim ◽  
Samya M. A. Hegazy

Context: Having premature and very low birth weight infants in the Neonatal Intensive Care Unit (NICU), is disempowering for mothers as they lost autonomy over their behavior and lost autonomy over beginning to establish a close relationship with their neonates. Mothers highly value Breastfeeding/breast milk feeding as it is the ‘one thing that only the mother can do to protect and improve their neonates' health. Aim: Evaluate the effect of colostrum feeding intervention on the clinical and nutritional outcomes of very low birth weight infant. Methods: A quasi-experimental research design utilized to achieve the aim of this study. A convenient sample of 80 mothers of very low birth weight infants subjected to colostrum feeding intervention program. Their 80 very low birth weight infants (divided randomly into two groups) study and control groups to examine the effect of the colostrum feeding intervention on their clinical and nutritional outcomes versus artificial milk feeding. Three research tools used that were structured interview questionnaire, mothers’ practice observation checklist, and very low birth weight clinical and Nutritional outcomes’ record. Results: the study reveals a significant improvement of mother knowledge and practices after colostrum feeding intervention at post and follow up compared to their pre-intervention level. The study also revealed a statistically significant difference in all clinical and nutritional outcomes between infants of the study and control groups. Conclusion: A significant improvement in mothers’ knowledge and practice regarding colostrum feeding intervention. The study group of very low birth weight infants had a rapid growth rate, better nutritional outcomes, lesser complications compared with the control group. The study recommended tailored intervention programs for mother that expecting a very low birth weight infant. Besides, policies for training midwives at maternity centers and hospitals early to initiate colostrum feeding. Further research with larger sample size recommended to determine if early colostrum administration can affect positively on very low birth weight infants outcomes.


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