Is Bovine Milk a Health Hazard?

PEDIATRICS ◽  
1985 ◽  
Vol 75 (1) ◽  
pp. 182-186
Author(s):  
Frank A. Oski
Keyword(s):  
Juvenile Delinquency ◽  
Potential Role ◽  
Health Hazard ◽  
Bovine Milk ◽  
Recurrent Abdominal Pain ◽  
Deficiency Anemia ◽  
First Year ◽  
Milk Allergy ◽  
Whole Milk ◽  
First Year Of Life

Whole bovine milk should not be fed to infants during the first year of life because of its association with occult gastrointestinal bleeding, iron deficiency anemia, and cow's milk allergy. The consumption of whole milk after the first year of life should be discouraged because of its potential role in a variety of disorders including atherosclerosis, recurrent abdominal pain of childhood, cataracts, milk-borne infections, and juvenile delinquency.

Health Hazards of Cow's Milk

PEDIATRICS ◽  
1985 ◽  
Vol 76 (6) ◽  
pp. 1021-1022
Author(s):  
◽  
O. TÖNZ ◽  
Keyword(s):  
Potential Role ◽  
Bovine Milk ◽  
Recurrent Abdominal Pain ◽  
Deficiency Anemia ◽  
Cow’S Milk ◽  
First Year ◽  
Cow's Milk ◽  
Whole Milk ◽  
First Year Of Life ◽  
Milk Feeding

To the Editor.— In a recent Pediatrics' supplement, Oski1 reviewed potential hazards of bovine milk-feeding and came to the conclusion that: Whole bovine milk should not be fed to infants during the first year of life because of its association with occult gastrointestinal bleeding, iron deficiency anemia, and cow's milk allergy. The consumption of whole milk after the first year of life should be discouraged because of its potential role in a variety of disorders including atherosclerosis, recurrent abdominal pain of childhood, cataracts, milk-borne infections, and juvenile delinquency.

Health Hazards of Cow's Milk

PEDIATRICS ◽  
1985 ◽  
Vol 76 (6) ◽  
pp. 1022-1023
Author(s):  
FRANK A. OSKI
Keyword(s):  
Feeding Practices ◽  
Health Hazards ◽  
Cow’S Milk ◽  
First Year ◽  
International Debate ◽  
Cow's Milk ◽  
Whole Milk ◽  
The World ◽  
First Year Of Life

In Reply.— An exchange of letters in a journal is an unsatisfactory forum to conduct an international debate but I feel compelled to respond to the correspondence of Professor Tönz. Professor Tönz expresses concern that my remarks may be interpreted as "recommending the abolishment of feeding practices that have developed over the centuries..." Are the feeding practices that Professor Tönz has in mind the introduction of whole cow's milk before the infant is 1 year of age or the use of whole milk after the first year of life? Neither practice has been in place for centuries "all over the world."

CHARACTERISTICS OF THE METABOLIC STATUS OF CHILDREN OF THE FIRST YEAR OF LIFE WITH PROTEIN-ENERGY DEFICIENCY DEPENDING ON THE GESTATIONAL AGE AT BIRTH

2020 ◽  
Vol 65 (7) ◽  
pp. 405-410
Author(s):  
I. V. Gorbacheva ◽  
O. U. Kuznetsova ◽  
F. N. Gilmiyarova ◽  
D. V. Pechkurov ◽  
L. N. Vinogradova
Keyword(s):  
Preterm Infants ◽  
Gestational Age ◽  
Protein Energy Malnutrition ◽  
Transferrin Saturation ◽  
Deficiency Anemia ◽  
First Year ◽  
Content Increase ◽  
Term Infants ◽  
Protein Energy ◽  
First Year Of Life

Comparative analysis of energy-plastic exchange indicators in mature and premature children of the first year of life in the development of protein-energy malnutrition (PEM) was carried out. Unidirectional changes are revealed, including an increase in creatinine, lactate and creatine phosphokinase activity levels, suggesting a n increasing muscle mass deficit against the background of glucose anaerobic oxidation activation. In preterm infants, glucose and triacylglicerine levels decrease, which reflects uncompensated insufficiency of energy substrates and, accordingly, ATP level. Multidirectional deviations in metabolism are pyruvate and ATP content: increase in full-term infants and decrease in preterm infants, that should be taken into account when monitoring condition of children with PEM. A significant decrease of pyruvic acid in preterm infants against the background of the levels of total protein, albumin, hemoglobin, and transferrin, not exceeding reference values, can obviously testify to the active use of this integral metabolite to maintain the fund of substituted amino acids. Development of this pathology in both mature and premature infants creates a pre-morbid background for iron deficiency anemia-diagnostic panel, which should be supplemented by calculation of transferrin saturation coefficient. Regardless of gestational age in childbirth during the formation of PEM, the lipid spectrum is rearranged according to atherogenic type: at normal values of total cholesterol, there is a significant increase in low and very low density lipoproteins with an increase in the atherogenicity coefficient. This singles out children with the pathology in question as a risk group for the development of the atherosclerotic process later, which justifies the recommendation to control the lipid profile in children of the first year of life.

scholarly journals Human Milk Adiponectin and Leptin and Infant Body Composition over the First 12 Months of Lactation

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 1125 ◽  
Author(s):  
Zoya Gridneva ◽  
Sambavi Kugananthan ◽  
Alethea Rea ◽  
Ching Lai ◽  
Leigh Ward ◽  
...  
Keyword(s):  
Body Composition ◽  
Human Milk ◽  
Term Infant ◽  
Fat Free Mass ◽  
First Year ◽  
Feeding Frequency ◽  
Critical Window ◽  
Whole Milk ◽  
Daily Intakes ◽  
First Year Of Life

Human milk (HM) adipokines may influence infant feeding patterns, appetite regulation, and body composition (BC). The associations between concentrations/calculated daily intakes (CDI) of HM adipokines in the first 12 months postpartum and maternal/term infant BC, and infant breastfeeding parameters were investigated. BC of breastfeeding dyads (n = 20) was measured at 2, 5, 9, and/or 12 months postpartum with ultrasound skinfolds (infants) and bioimpedance spectroscopy (infants/mothers). 24-h milk intake and feeding frequency were measured along with whole milk adiponectin and skim and whole milk leptin (SML and WML) and CDI were calculated. Statistical analysis used linear regression/mixed effects models; results were adjusted for multiple comparisons. Adipokine concentrations did not associate with infant BC. Higher CDI of adiponectin were associated with lower infant fat-free mass (FFM; p = 0.005) and FFM index (FFMI; p = 0.009) and higher fat mass (FM; p < 0.001), FM index (FMI; p < 0.001), and %FM (p < 0.001). Higher CDI of SML were associated with higher infant FM (p < 0.001), FMI (p < 0.001), and %FM (p = 0.002). At 12 months, higher CDI of WML were associated with larger increases in infant adiposity (2–12 month: FM, p = 0.0006; %FM, p = 0.0004); higher CDI of SML were associated with a larger decrease in FFMI (5–12 months: p = 0.0004). Intakes of HM adipokines differentially influence development of infant BC in the first year of life, which is a critical window of infant programming and may potentially influence risk of later disease via modulation of BC.

Early risk factors for cow's milk allergy in children in the first year of life

2018 ◽  
Vol 39 (6) ◽  
pp. e44-e54 ◽  
Author(s):  
Izabela Sardecka ◽  
Ewa Łoś-Rycharska ◽  
Hanna Ludwig ◽  
Julia Gawryjołek ◽  
Aneta Krogulska
Keyword(s):  
Risk Factors ◽  
Cow’S Milk Allergy ◽  
Cow’S Milk ◽  
First Year ◽  
Milk Allergy ◽  
Cow's Milk ◽  
Cow's Milk Allergy ◽  
Early Risk ◽  
Early Risk Factors ◽  
First Year Of Life

Presence of growth hormone-binding proteins in cattle plasma and milk

1993 ◽  
Vol 138 (1) ◽  
pp. 91-98 ◽  
Author(s):  
A. Devolder ◽  
R. Renaville ◽  
M. Sneyers ◽  
I. Callebaut ◽  
S. Massart ◽  
...  
Keyword(s):  
Binding Proteins ◽  
Potential Role ◽  
Specific Binding ◽  
First Year ◽  
Adult Cattle ◽  
Molecular Weights ◽  
Gh Receptor ◽  
First Year Of Life ◽  
Two Peaks

ABSTRACT The presence of GH-binding proteins (GHBPs) in the plasma of adult cattle was investigated using Sephadex G-200 filtration, Western ligand blotting and Western blotting. The changes in the concentration of GHBP in the plasma of dairy half-sister heifers during the first year of life as well as the presence of GHBP in milk were also investigated. When analytical chromatography (on a 1·6 × 100 cm column) was performed, five peaks of recombinant bovine GH (rbGH)-associated radioactivity were revealed in cattle plasma; the first peak, which appeared near the void volume, was presumed to represent aggregates, the second (Mr 290 kDa) and the third peaks (Mr 75 kDa) corresponded to specific rbGH–GHBP complexes; the last two peaks representing free 125I-labelled rbGH and Na[125I]. Western ligand blotting revealed multiple GHBPs. Three major bands were observed at approximately 190, 58 and 31 kDa; an excess of unlabelled hormone blocked the binding of 125I-labelled rbGH. Minor non-specific binding bands were also detected in cattle plasma with molecular weights between 40 and 136 kDa. One monoclonal antibody (8H7) produced against synthetic peptide (amino acids 54–63 of the extracellular domain of the bovine GH receptor) specifically interacted with 190 and 58 kDa bands while the 31 kDa band was not recognized. Finally, Western ligand blots were performed to evaluate the changes in plasma GHBP during the first year of life in 55 dairy half-sister heifers and to identify GHBP in milk. In plasma, the intensity of the 31 kDa band varied greatly between animals while the other specific bands remained stable. In milk, all specific GHBP bands observed by Western ligand blotting disappeared a few days after parturition. In conclusion, these results demonstrate the presence of GHBPs in cattle plasma and milk. There were important variations in GHBP between dairy halfsister heifers during the first year of life but the potential role of these binding proteins in the regulation of the biological activity of GH in ruminants and their functions in milk remain to be determined. Journal of Endocrinology (1993) 138, 91–98

scholarly journals Features of the course of new coronavirus infection in newborns and first-year infants

2021 ◽  
Vol 24 (3) ◽  
pp. 203-208
Author(s):  
Natalya A. Kharitonova ◽  
Milana A. Basargina ◽  
Mariya S. Illarionova ◽  
Marina I. Nesterovich
Keyword(s):  
Surgical Pathology ◽  
Deficiency Anemia ◽  
First Year ◽  
Runny Nose ◽  
National Medical ◽  
Moderate Disease ◽  
Course Changes ◽  
Echocardiographic Examination ◽  
Coronavirus Infection ◽  
First Year Of Life

The aim of the study was to assess the features of the course of new coronavirus infection in newborns and children of the first year of life. Materials and methods. Thirty-six children aged eight days to 11 months were hospitalized in the covid centre of the National Medical Research Center for Children’s Health (of which nine children were transferred from one of the surgical hospitals in Moscow due to the contact with SARS-CoV-2). Results. Despite severe concomitant surgical pathology in 25% of patients, 98% of children had mild to moderate disease. Febrile temperature (up to a maximum of 39 oC) was observed in 4 infants, sub-febrile temperature in 5 people. In other children, for the entire period of treatment, there was no increase in temperature. Mothers’ complaints about lethargy dominated the clinical picture of the disease, followed by refusal to eat, runny nose, sneezing, swallowing voice, coughing, shortness of breath in their children. During the examination, the following signs were revealed: yawn hyperemia, mucous separated from the nose, hard breathing and dry wheezing (in 1 infant). The general blood test showed anemia (mostly related to prematurity anemia, or iron deficiency anemia), leftward leukocytosis (due to concomitant surgical pathology), leukopenia, various changes in the leukocytic formula of blood. In some instances, thrombocytopenia increased in D-dimer C-RP, procalcitonin, ferritin, bilirubin, and alanine aminotransferase. In only six infants with a moderate disease course, changes characteristic of a new coronavirus infection were identified on the chest CT scan. Six infantas had rhythm disorders detected in electrocardiographic examination (no deviations were found in echocardiographic examination). Conclusion. According to both foreign literature and data obtained during our study, it can be concluded that, compared with adults, infants have a milder course of the disease and less pronounced changes obtained during laboratory and instrumental studies.

scholarly journals Iron Status of Infants in the First Year of Life in Northern Taiwan

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 139 ◽  
Author(s):  
Chiao-Ming Chen ◽  
Shu-Ci Mu ◽  
Chun-Kuang Shih ◽  
Yi-Ling Chen ◽  
Li-Yi Tsai ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Nutritional Status ◽  
Iron Status ◽  
Deficiency Anemia ◽  
Anthropometric Measurement ◽  
First Year ◽  
Iron Intake ◽  
Breastfed Infants ◽  
First Year Of Life ◽  
Northern Taiwan

Iron deficiency (ID) and iron deficiency anemia (IDA) typically occur in developing countries. Notably, ID and IDA can affect an infant’s emotion, cognition, and development. Breast milk is considered the best food for infants. However, recent studies have indicated that breastfeeding for more than six months increases the risk of ID. This study investigated the prevalence of ID and IDA, as well as the association between feeding type and iron nutritional status in northern Taiwan. A cross-sectional study was conducted on infants who returned to the well-baby clinic for routine examination from October 2012 to January 2014. Overall, 509 infants aged 1–12 months completed the iron nutritional status analysis, anthropometric measurement, and dietary intake assessment, including milk and complementary foods. The results revealed that 49 (10%) and 21 (4%) infants in their first year of life had ID and IDA, respectively, based on the World Health Organization criteria. Breastfed infants had a higher prevalence rate of ID and IDA than mixed-fed and formula-fed infants (p < 0.001). Regarding biomarkers of iron status, plasma hemoglobin (Hb), ferritin, and transferrin saturation (%) levels were significantly lower in ID and IDA groups. The prevalence of ID and IDA were 3.7% and 2.7%, respectively, in infants under six months of age, but increased to 20.4% and 6.6%, respectively, in infants above six months of age. The healthy group had a higher total iron intake than ID and IDA groups, mainly derived from infant formula. The total dietary iron intake was positively correlated with infants’ Hb levels. Compared with formula-fed infants, the logistic regression revealed that the odds ratio for ID was 2.157 (95% confidence interval [CI]: 1.369–3.399) and that for IDA was 4.196 (95% CI: 1.780–9.887) among breastfed infants (p < 0.001) after adjusted for all confounding factors (including gestational week, birthweight, sex, body weight percentile, body length percentile, age of infants, mothers’ BMI, gestational weight gain, education level, and hemoglobin level before delivery). In conclusion, our results determined that breastfeeding was associated with an increased the prevalence of ID and/or IDA, especially in infants above six months. This suggests that mothers who prolonged breastfeed after six months could provide high-quality iron-rich foods to reduce the prevalence of ID and IDA.

scholarly journals Modern approaches and some principles of complementary feeding in the first year of life

2021 ◽  
Vol 16 (5) ◽  
pp. 361-367
Author(s):  
S.L. Nyankovskyy ◽  
О.S. Nyankovska ◽  
M.S. Yatsula ◽  
O.R. Sadova
Keyword(s):  
Complementary Feeding ◽  
Feeding Habits ◽  
Allergic Diseases ◽  
Deficiency Anemia ◽  
First Year ◽  
Eating Patterns ◽  
First Year Of Life ◽  
The Impact ◽  
Adult Food ◽  
Diet Model

Early life feeding habits may potentially alter future metabolism and health in adulthood. The period of the first complementary feeding is the time when children introduce new food different from breast milk and forms a new diet model for their family. This period is important in the transition of the baby from breastfeeding to adult food and is necessary both to provide nutrients for body growth and mental and social development. The timing of supplementation and model of complementary feeding changed over time. Recent literature data show the growing interest and concern of the scientific community about the impact of terms and methods of supplementation on the onset of some diseases, such as iron deficiency anemia, obesity, allergic diseases, celiac disease, diabetes, and others. Nutritional preferences formed in early childhood impact health and eating patterns in adulthood.

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