Pediatric Defibrillation: Importance of Paddle Size in Determining Transthoracic Impedance

PEDIATRICS ◽  
1988 ◽  
Vol 82 (6) ◽  
pp. 914-918
Author(s):  
Dianne L. Atkins ◽  
Sara Sirna ◽  
Robert Kieso ◽  
Francis Charbonnier ◽  
Richard E. Kerber
Keyword(s):  
Body Weight ◽  
Body Surface ◽  
Coupling Agent ◽  
Major Determinant ◽  
Pulse Technique ◽  
Test Pulse ◽  
Surface Areas ◽  
Transthoracic Impedance ◽  
Transthoracic Resistance

Transthoracic impedance is a major determinant of successful defibrillation or cardioversion, but no data are available concerning the range and determinants of transthoracic impedance in children. Transthoracic impedance was measured in ten ambulatory infants, 6 weeks to 9 months of age, and 37 children, 1.5 to 15 years of age, using a previously validated "test pulse" technique that measures transthoracic impedance without actually delivering a shock. We used hand-held "pediatric" (21 cm2) and "adult" (83 cm2) electrode paddles coated with either Redux paste or Redux creme. Transthoracic impedance in children was 108 ± 24 Ω (range 61 to 212 Ω) using pediatric paddles. Using adult paddles lowered the transthoracic resistance by 47% to 57 ± 11 Ω (range 29 to 101 Ω), P < .05. In infants, transthoracic impedance (measured only with pediatric paddles) was 94 ± 17 Ω (range 74 to 124 Ω). Using Redux paste as the coupling agent reduced transthoracic impedance by 13% (P < .05). Transthoracic impedance was significantly but poorly related to body weight and body surface areas, but the correlations were not sufficiently high to be clinically useful. These data indicate that the larger adult electrode paddles will minimize transthoracic impedance and should be used when the child's thorax is large enough to permit electrode to chest contact over the entire paddle surface. This transition occurred at an approximate weight of 10 kg.

Determination of body surface area in the rhesus monkey

1976 ◽  
Vol 40 (1) ◽  
pp. 101-104 ◽  
Author(s):  
C. T. Liu ◽  
G. A. Higbee
Keyword(s):  
Body Weight ◽  
Rhesus Monkey ◽  
Body Surface ◽  
Rhesus Monkeys ◽  
Goodness Of Fit ◽  
Rapid Determination ◽  
K Value ◽  
Male And Female ◽  
Surface Areas

Body surface areas (BSA) of 31 apparently normal rhesus monkeys of both sexes weighing 3.2–5.3 kg were determined by the direct skinning technique. The range of measured BSA was 1,940–3,020 cm2 (mean = 2,430 cm2). The BSA values of male and female monkeys were not significantly different. The K value, calculated as the ratio of BSA (cm2)/body wt2/3 (kg), was 969 +/- 15 (SE). Based on the principle of least squares for goodness of fit between the measured and calculated BSA, the best equation was determined to be (see article). A nomogram was constructed for rapid determination of the BSA of rhesus monkeys with known body weight and lengths (head to anus). Monkey BSA could also be computed by multiplying the DuBois human BSA equation by a factor of 1.147 for the head-to-anus measure of length or by 0.891 for the head-to-heel measurement.

scholarly journals Modified formulas for calculation of encephalization: quotient in dogs

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Saganuwan Alhaji Saganuwan
Keyword(s):  
Body Weight ◽  
Body Surface ◽  
The Body ◽  
German Shepherd ◽  
Public Places ◽  
Brain Mass ◽  
Doberman Pinscher ◽  
Surface Areas ◽  
Encephalization Quotient ◽  
Key Factor

Abstract Objective Dogs are a breed of animals that play important roles in security service, companionship, hunting, guard, work and models of research for application in humans. Intelligence is the key factor to success in life, most especially for dogs that are used for security purposes at the airports, seaports, public places, houses, schools and farms. However, it has been reported that there is correlation between intelligence, body weight, height and craniometry in human. In view of this, literatures were searched on body weight, height and body surface areas of ten dogs with intent to determining their comparative level of intelligence using encephalization quotient. Results Findings revealed that dogs have relationship of brain allometry with human as proven by encephalization quotient $$\left( {{\text{EQ}}} \right)\, = \,{\text{Brain Mass}}/0.{14}\, \times \,{\text{Body weight}}^{{0.{528}}} ,{\text{ Brain Mass}}/0.{12}\, \times \,{\text{Body Weight}}^{{0.{66}}}$$ EQ = Brain Mass / 0.14 × Body weight 0.528 , Brain Mass / 0.12 × Body Weight 0.66 and Brain Mass (E)  =  kpβ, where p is the body weight; k  =  0.14 and β = 0.528, respectively. Saganuwa’s formula yielded better results as compared with the other formulas. Dogs with body surface area (BSA), weight and height similar to that of human are the most intelligent. Doberman pinscher is the most intelligent followed by German shepherd, Labrador retriever, Golden retriever, respectively.

Sodium Regulation and Adaptation to Fresh Water in Gammarid Crustaceans

1968 ◽  
Vol 48 (2) ◽  
pp. 359-380
Author(s):  
D. W. SUTCLIFFE
Keyword(s):  
Body Weight ◽  
Fresh Water ◽  
Body Surface ◽  
Sea Water ◽  
Sodium Concentration ◽  
The Body ◽  
Outward Diffusion ◽  
Gammarus Zaddachi ◽  
Freshwater Habitats ◽  
Sodium Regulation

1. Sodium uptake and loss rates are given for three gammarids acclimatized to media ranging from fresh water to undiluted sea water. 2. In Gammarus zaddachi and G. tigrinus the sodium transporting system at the body surface is half-saturated at an external concentration of about 1 mM/l. and fully saturated at about 10 mM/l. sodium. In Marinogammarus finmarchicus the respective concentrations are six to ten times higher. 3. M. finmarchicus is more permeable to water and salts than G. zaddachi and G. tigrinus. Estimated urine flow rates were equivalent to 6.5% body weight/hr./ osmole gradient at 10°C. in M. finmarchicus and 2.8% body weight/hr./osmole gradient in G. zaddachi. The permeability of the body surface to outward diffusion of sodium was four times higher in M. finmarchicus, but sodium losses across the body surface represent at least 50% of the total losses in both M. finmarchicus and G. zaddachi. 4. Calculations suggest that G. zaddachi produces urine slightly hypotonic to the blood when acclimatized to the range 20% down to 2% sea water. In fresh water the urine sodium concentration is reduced to a very low level. 5. The process of adaptation to fresh water in gammarid crustaceans is illustrated with reference to a series of species from marine, brackish and freshwater habitats.

Developmental pattern of hypercapnic and hypoxic ventilatory responses from childhood to adulthood

1994 ◽  
Vol 76 (1) ◽  
pp. 314-320 ◽  
Author(s):  
C. L. Marcus ◽  
W. B. Glomb ◽  
D. J. Basinski ◽  
S. L. Davidson ◽  
T. G. Keens
Keyword(s):  
Heart Rate ◽  
Body Weight ◽  
Body Size ◽  
Respiratory Rate ◽  
Body Surface ◽  
Vital Capacity ◽  
Developmental Pattern ◽  
Ventilatory Responses ◽  
End Tidal ◽  
Arterial O2 Saturation

The developmental pattern of ventilatory responses, through childhood and puberty into adulthood, is not known. Therefore we studied hypercapnic (HCVR) and hypoxic ventilatory responses (HOVR) in 59 subjects (29 males and 30 females) 4–49 yr of age, of whom 35 were children ( < 18 yr old). There was a significant correlation between HCVR and weight (r = 0.33, P < 0.02), vital capacity (r = 0.30, P < 0.05), and body surface area (r = 0.30, P < 0.05) but not height (r = 0.22, NS). There was no correlation between HOVR and any of the correcting factors. To account for disparities in body size, volume-related results were scaled for body weight. The HCVR corrected for weight (HCVR/WT) decreased with age (r = -0.57, P < 0.001). HCVR/WT was significantly higher in children than in adults (0.056 +/- 0.024 vs. 0.032 +/- 0.015 l.kg-1 x min-1. Torr end-tidal PCO2-1, P < 0.001). The (tidal volume/inspiratory duration)/weight, respiratory rate, and heart rate responses to hypercapnia were increased in the children, and the CO2 threshold was lower (36 +/- 5 vs. 40 +/- 6 Torr, P < 0.05). Similarly, the HOVR corrected for weight (HOVR/WT) decreased with age (r = 0.34, P < 0.05), and HOVR/WT was significantly higher in children than in adults (-0.035 +/- 0.017 vs. -0.024 +/- 0.016 l.kg-1 x min-1.% arterial O2 saturation-1, P < 0.02). The respiratory rate and heart rate responses to hypoxia were increased in the children. We conclude that rebreathing HCVR and HOVR are higher during childhood than during adulthood.

Gill and Body Surface Areas of the Carp in relation to Body Mass, With Special Reference To The Metabolism-Size Relationship

1985 ◽  
Vol 117 (1) ◽  
pp. 1-14 ◽  
Author(s):  
SHIN OIKAWA ◽  
YASUO ITAZAWA
Keyword(s):  
Special Reference ◽  
Body Mass ◽  
Body Surface ◽  
Larval Stage ◽  
The Body ◽  
Positive Allometry ◽  
Surface Areas ◽  
Gill Area ◽  
Resting Metabolism ◽  
The Relationship

The relationships of resting metabolism per unit mass of body to gill and body surface areas were examined by measuring gill, body surface and fin areas of carp ranging from 0.0016 to 2250g. There was a triphasic allometry for the relationship between gill area and body mass: during the prelarval (0.0016–0.003 g) and postlarval (0.003–0.2g) stages there was a positive allometry (slopes of 7.066 and 1.222, respectively), during the juvenile and later stages (0.2–2250 g) there was a negative allometry with a slope of 0.794. There was a diphasic negative allometry for the relationship between surface area of the body or the fins and body mass, with a slope of 0.596 or 0.523 during the larval stage and 0.664 or 0.724 during the juvenile and later stages, respectively. Except for the 3rd phase (juvenile to adult) of gill area, these slopes were significantly different (P&lt;0.01) from the slope for the relationship between resting metabolism and body mass of intact carp (0.84; value from Winberg, 1956). It is considered, therefore, that gill, body surface and fin areas do not directly regulate the resting metabolism of the fish, in the larval stage at least.

New formula for predicting standard liver and spleen volumes in Chinese adults

2019 ◽  
Author(s):  
Longbao Yang ◽  
Gang Zhao ◽  
Xinxing Tantai ◽  
Cailan Xiao ◽  
Caifeng Yang ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Surface Area ◽  
Body Surface Area ◽  
Body Surface ◽  
Liver Volume ◽  
Body Height ◽  
Spleen Volume ◽  
Chinese Adults ◽  
Volume Formula

Abstract BACKGROUNDThe liver volume and spleen volum are useful index for cirrhosis patients with esphageal varices. But the calculation of the volume is time-consuming and boring. To solve the problem, we successfully established the liver and spleen volume formula using the body surface area. We compared the liver volume formula with other four formulas, which be proved with highest accuracy and lowest error. Until now, except for the new spleen volume formula in the research, there are few reports about it.AIMTo obtain a reference range of morphological indices, and to establish a formula to accurately predict the standard liver and spleen volumes in Chinese adults.METHODSComputed tomography was used to calculate the estimated total liver volume and spleen volume of 305 Chinese adults without any diseases which could influence the volumes of these two organs. Gender, age, body height, body weight, body surface area and body mass index were determined. Correlation analysis and step-wise multiple linear regression analysis were performed to evaluate the impact of each parameter on the liver and spleen volumes, and then a formula to predict the liver and spleen volumes was established. Finally, the results obtained with the new liver volume formula with existing formulas in a validation group were compared.RESULTSThe average liver and spleen volume values were 1043.18 ± 244.60 cm3 and 175.07 ± 88.15 cm3, respectively. Age, body height, body weight, body surface area and body mass index were significantly correlated with liver and spleen volume. Body surface area showed the strongest correlation with liver volume and spleen volume( p<0.005 and p<0.001). Based on these results, new formulas to calculate the standard liver volume and standard spleen volume were established.CONCLUSIONSCompared the new liver volume formula with the existing formula, it is found that the new liver volume is more accurate. And the accuracy of the spleen volume formula is acceptable. Core tip: To solve the problem of time-consuming and boring in calculating the liver and spleen volume, we successfully established the liver and spleen volume formula can be used in Chinese adult. Though there are some reports about the liver volume, but it is different in spleen volume. The liver volume and spleen volume radio is an useful index to predict the esophageal varices and bleeding risk for cirrhosis patients. Only liver volume formula is not enough, the finding of the spleen volume is very meaningful.

Efficacy of body weight vs body surface area-based prednisolone regimen in nephrotic syndrome

2020 ◽  
Vol 24 (7) ◽  
pp. 622-629 ◽  
Author(s):  
Biswanath Basu ◽  
Suman Bhattacharyya ◽  
Shilpita Barua ◽  
Abhisek Naskar ◽  
Birendranath Roy
Keyword(s):  
Body Weight ◽  
Nephrotic Syndrome ◽  
Surface Area ◽  
Body Surface Area ◽  
Body Surface

Urea is the Best Molecule to Target Adequacy of Peritoneal Dialysis

2000 ◽  
Vol 20 (2_suppl) ◽  
pp. 58-64 ◽  
Author(s):  
Frank A. Gotch
Keyword(s):  
Peritoneal Dialysis ◽  
Body Surface ◽  
Residual Renal Function ◽  
Dialysis Dose ◽  
Surface Areas ◽  
Wide Range ◽  
Anephric Patients ◽  
Dialysis Outcomes ◽  
Two Parameters ◽  
Urea Distribution Volume

For hemodialysis, a large base of data shows the validity of modelling the dialysis dose and reliably estimating protein intake from equilibrated Kt/V urea (eKt/VU), the total dialyzer urea clearance provided during each treatment divided by the urea distribution volume. An eKt/VU of 1.05 thrice weekly is judged adequate, but is still under study. In continuous ambulatory peritoneal dialysis (CAPD), two dosage criteria are widely recognized: continuous (“standard”) Kt/VU (stdKt/VU = 2.0 weekly), and total creatinine (Cr) clearance normalized to body surface area (KCrT = 70 L/week/1.73 m2). The CANUSA study concluded that a stdKt/VU of 2.1 and a KCrT of 70 L/week/1.73 m2 gave equivalent clinical outcomes. The Dialysis Outcomes Quality Initiative (DOQI) recommends values of 2.0 and 60 L/ week/1.73 m2 respectively. An analysis of these two parameters for males and females over a wide range of body surface areas (BSAs) was done and the analysis showed: ( 1 ) The U and Cr dose criteria are incommensurable—that is, they can virtually never be achieved simultaneously in anephric patients. ( 2 ) The Cr criterion varies widely with the sex of the patient and with the BSA-dependent variation in stdKt/VU over a range of 2.1 to 3.0. ( 3 ) The U criterion always produces a KCrT < 60 L/week/1.73 m2 in females and 60 – 70 L/ week/1.73 m2 in males. With respect to U and Cr, the CANUSA results were concluded to be valid in patients with substantial residual renal function, but probably not applicable to anephric patients where the doses are clearly incommensurable.

scholarly journals Comparative study of rules employed for calculation of pediatric drug dosage

2005 ◽  
Vol 13 (2) ◽  
pp. 114-119 ◽  
Author(s):  
Gracieli Prado Elias ◽  
Cristina Antoniali ◽  
Ronaldo Célio Mariano
Keyword(s):  
Body Surface ◽  
Pediatric Dentistry ◽  
Drug Dosage ◽  
The Body ◽  
Clinical Use ◽  
Age Group ◽  
Pediatric Drug ◽  
Parametric Test ◽  
Tukey Test ◽  
Surface Areas

The present study was conducted to evaluate the utilization of Clark's, Salisbury and Penna's rules and the Body Surface Area (BSA) formula for calculation of pediatric drug dosage, as well as their reliability and viability in the clinical use. These rules are frequently cited in the literature, but much controversy still exists with regards to their use. The pediatric drug dosage was calculated by utilization of the aforementioned rules and using the drugs Paracetamol, Dipyrone, Diclofenac Potassium, Nimesulide, Amoxicillin and Erythromycin, widely employed in Pediatric Dentistry. Weight and body surface areas were considered of children with ages between 1 and 12 years old as well as the dosage for the adult. The pediatric dosages achieved were compared to the predetermined dosages in mg kg-1 herein-named standard dosages. The results were submitted to the parametric test ANOVA and to the Tukey test (p<0,05). The antibiotics and Diclofenac provides acceptable utilization of the rules in pediatric dentistry, however for the Dipyrone, the dosages obtained by the rules suggest their clinical ineffectiveness. For the Paracetamol, the Penna's rule and the BSA formula should not be clinically employed, especially for children between 1 and 5 years old, once such dosages were much close to the hepatotoxic dosage of the drug. It can be concluded that the use of the rules for safe calculation of the pediatric drug dosage is possible and it depends on the used drug and age group.

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