Embolization of Ectopic Kidney to Control Incontinence

PEDIATRICS ◽  
1990 ◽  
Vol 85 (2) ◽  
pp. 217-219
Author(s):  
B. DE GROOTE ◽  
P. VAN LAER ◽  
K. MAURUS ◽  
J. P. VAN BIERVLIET ◽  
L. MEEUS

Ureteral ectopy in girls can cause dribbling incontinence if the ectopic ureter ends below the continence mechanism of bladder neck and external sphincter. Approximately 25% of ectopic ureters drain into the vagina. The corresponding renal tissue is often hypoplastic or dysplastic. Surgery used to be the treatment of choice. Depending on the quality of the corresponding renal tissue, one had the choice between ureter reimplantation or partial or total nephrectomy. We succeeded in treating a girl with a hypoplastic kidney and an ectopic ureter nonsurgically by embolizing the corresponding renal artery. CASE REPORT A 5-½-year-old girl had leakage of urine in spite of a normal voiding pattern.

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Demisew Amenu ◽  
Andebet Asmare ◽  
Ahmed Siraj

Abstract Background Diagnosing urinary incontinence from organic causes such as ectopic ureter is particularly important because of the potential for cure by surgical correction. The prevalence of ectopic ureter is uncertain because many are asymptomatic and the diagnosis is usually overlooked. Eighty percent of ectopic ureters in females are often associated with duplex kidney. However, an ectopic ureter draining a single-system ectopic dysplastic/atrophic but functioning kidney is rare, especially in females. The overall long-term continence rate after successful correction of ectopic ureter is satisfactory. Case presentation This case is reported to highlight a rare situation, where a 22-year-old nulligravid Ethiopian women presented with a complaint of continuous wetting of her underwear since childhood, but she had normal voiding pattern. Localized right pelvic kidney ultrasound and computed tomography scan with contrast revealed right ectopic ureter and atrophied ipsilateral pelvic kidney with good function. Surgical reimplantation through vaginal approach was performed, and the outcome was good. The patient’s subsequent follow-ups were uneventful. Conclusion An extramural vaginal ectopic ureter is better accessed through transvaginal approach than abdominal, especially when it is associated with pelvic ectopic kidney. This modified approach is less invasive and has lower morbidity and better success rate than a transabdominal approach.


Materials ◽  
2021 ◽  
Vol 14 (11) ◽  
pp. 2939
Author(s):  
Aziz Eftekhari ◽  
Solmaz Maleki Dizaj ◽  
Elham Ahmadian ◽  
Agata Przekora ◽  
Seyed Mahdi Hosseiniyan Khatibi ◽  
...  

The implementation of nanomedicine not only provides enhanced drug solubility and reduced off-target adverse effects, but also offers novel theranostic approaches in clinical practice. The increasing number of studies on the application of nanomaterials in kidney therapies has provided hope in a more efficient strategy for the treatment of renal diseases. The combination of biotechnology, material science and nanotechnology has rapidly gained momentum in the realm of therapeutic medicine. The establishment of the bedrock of this emerging field has been initiated and an exponential progress is observed which might significantly improve the quality of human life. In this context, several approaches based on nanomaterials have been applied in the treatment and regeneration of renal tissue. The presented review article in detail describes novel strategies for renal failure treatment with the use of various nanomaterials (including carbon nanotubes, nanofibrous membranes), mesenchymal stem cells-derived nanovesicles, and nanomaterial-based adsorbents and membranes that are used in wearable blood purification systems and synthetic kidneys.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Malou L. H. Snijders ◽  
Marina Zajec ◽  
Laurens A. J. Walter ◽  
Remco M. A. A. de Louw ◽  
Monique H. A. Oomen ◽  
...  

Abstract Optimal preservation and biobanking of renal tissue is vital for good diagnostics and subsequent research. Optimal cutting temperature (OCT) compound is a commonly used embedding medium for freezing tissue samples. However, due to interfering polymers in OCT, analysis as mass spectrometry (MS) is difficult. We investigated if the replacement of OCT with Cryo-Gel as embedding compound for renal biopsies would enable proteomics and not disturb other common techniques used in tissue diagnostics and research. For the present study, fresh renal samples were snap-frozen using Cryo-Gel, OCT and without embedding compound and evaluated using different techniques. In addition, tissue samples from normal spleen, skin, liver and colon were analyzed. Cryo-Gel embedded tissues showed good morphological preservation and no interference in immunohistochemical or immunofluorescent investigations. The quality of extracted RNA and DNA was good. The number of proteins identified using MS was similar between Cryo-Gel embedded samples, samples without embedding compound and OCT embedded samples. However, polymers in the OCT disturbed the signal in the MS, while this was not observed in the Cryo-Gel embedded samples. We conclude that embedding of renal biopsies in Cryo-Gel is an excellent and preferable alternative for OCT compound for both diagnostic and research purposes, especially in those cases where proteomic analysis might be necessary.


2015 ◽  
Vol 10 (3) ◽  
pp. 202-204 ◽  
Author(s):  
Kirtishri Mishra ◽  
Christopher S Elliott

Ectopic ureters are a found in one of every 2000–4000 people. This abnormality can present with urinary tract infections, haematuria, and occasionally incontinence. Ectopic ureters traditionally follow the Weigert-Meyer Law, which describes the relationship of the lower and upper renal moieties. It states that the lower renal pole drains into a laterocranial ureteral orifice (and may reflux), while the upper renal pole drains into a mediocaudal ureteral orifice (and may be obstructed). If a duplicated ureter does not insert into the bladder, it by rule, originates from the upper pole. We present a case of a 42-year-old male who was incidentally found to have what appears to be an ectopic ureter draining from the lower renal pole into a structure contained in the scrotum, hence violating the Weigert-Meyer law.


2011 ◽  
Vol 2011 ◽  
pp. 1-3
Author(s):  
Joana Pereira ◽  
Angélica Osório ◽  
João Moreira-Pinto ◽  
José Cidade-Rodrigues ◽  
Carlos Enes ◽  
...  

Objective. To describe a simplified technique already used in our institution for several years in the open heminephrectomy for duplication anomalies, now performed through a retroperitoneal laparoscopic approach.Methods. The technique begins with upper pole parenchyma incision since the demarcation between the affected upper moiety and the healthy lower pole is easily established. The dissection proceeds until the urothelium of the collecting system is entered, which will guide further excision, minimizing damage of the surrounding structures. The vascular supply is then identified since the upper pole is attached to the remaining renal parenchyma only by these structures that can be safely divided. Dissection and division of the ectopic ureter is carried next.Results. The operative time was 188 minutes. The blood loss was not significant, and there were no other complications during the procedure. The patient was discharged home 48 hours after the procedure, without any early or late postoperative complications.Conclusion. We believe this simplified technique allows a safer excision of nonfunctioning upper pole renal tissue by avoiding the initial dissection of the renal hilum, which associated with the known advantages of a laparoscopic approach makes us consider it the procedure of choice for upper pole nephrectomy in children.


1982 ◽  
Vol 63 (s8) ◽  
pp. 227s-230s ◽  
Author(s):  
Louis Tobian ◽  
Susan Johnson-Hanlon ◽  
Mary Zitur ◽  
Junichi Iwai

1. When all renal tissue is removed from salt-fed Dahl S rats, the excessive amounts of a circulating humoral vasoconstrictor effect (or lack of a vasodilator effect) are abolished, and Dahl S rats become the equal of Dahl R rats with regard to these circulating vasoconstrictor effects. 2. Total nephrectomy of salt-fed S rats also alters circulating humoral agents so that vasoconstrictor responses to sympathetic nerve stimulation and to noradrenaline infusions are markedly diminished in a perfused hindquarters preparation. 3. Both these effects of total nephrectomy are seen only in S rats, not in R rats, although plasma renin levels are lower in S rats. Thus total nephrectomy must remove much more renin and angiotensin II in R rats. 4. The effect of total nephrectomy in S rats need not necessarily be the direct removal of circulating vasoconstrictor humoral agents issuing from the S kidney. It is quite possible that removal of S kidneys has a strong influence upon the release of circulating vasconstrictor or vasodilator agents emerging from other parts of the body. 6. These effects of total nephrectomy occurring solely in S rats add still more evidence pointing to a pivotal role for the kidney in the mechanism of the NaCl hypertension of Dahl S rats.


2021 ◽  
Vol 14 (3) ◽  
pp. 142-149
Author(s):  
A.A. Volkov ◽  
◽  
N.V. Budnik ◽  
O.N. Zuban ◽  
◽  
...  

Introduction. Currently, the basis for effective treatment of urinary tuberculosis (UT) is a combination of specific chemotherapy with reasonable surgical intervention and strict follow-up of the patient. Materials and methods. This literature review presents the evolution of methods of surgical treatment of renal and upper urinary tract tuberculosis over of 127 sources found for the review, 63 were selected. Results. Since UT is a very slowly progressive disease with minimal and imperceptible symptoms, often leading to irreversible organ damage, up to 75% of patients with this pathology undergo surgery. As follows from the results of recent studies, the emphasis of surgical treatment is increasingly shifting from ablative and organ-carrying techniques to reconstructive operations. Surgery for upper urinary tract tuberculosis continues to develop, but its results in advanced cases of destruction of renal tissue often remain unsatisfactory. Conclusions. The search for new methods of reconstructive interventions, the purpose of which is to preserve functioning renal-ureteral units and improve the quality of life of patients, remains relevant.


2020 ◽  
pp. 1-3
Author(s):  
Anssi Petas ◽  
Anssi Petas ◽  
Jouni Huttunen ◽  
Jukka Sairanen ◽  
Niilo Hendolin

Ectopic ureters are rare in the population. We report a case of an ectopic ureter draining into the urethra in a young female. The ectopic ureter was resected in robotic assisted surgery. The urinary continence was normal at 2 years follow-up


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