Neonatal Bilirubin Workshop

PEDIATRICS ◽  
1994 ◽  
Vol 94 (4) ◽  
pp. 537-540
Author(s):  
Lawrence M. Gartner ◽  
Charlotte S. Catz ◽  
Sumner J. Yaffe

A neonatal bilirubin workshop took place at The Rockefeller University on June 20 through 22, 1993 to consider controversial issues in the field of neonatal jaundice and bilirubin neurotoxicity, particularly as they relate to management. The conference was sponsored by the National Institute of Child Health and Human Development (Pregnancy and Perinatology Branch, Center for Mothers and Children), The Rockefeller University, and the Consiglio Nazionale delle Richerche (Italy). tk;4Presentations and discussion emphasized diagnosis, biochemistry, and mechanisms of bilirubin toxicity, the definition and consequences of kernicterus, and the appropriateness and safety of the various therapies currently in use. Identification of future research needs was an important agenda item. The conferees agreed that conventional management of jaundice in the newborn with phototherapy and exchange transfusion, as well as with phenobarbital in certain situations, had significantly reduced the occurrence of "traditional" kernicterus. However, the conferees acknowledged that the classical definition of kernicterus was in need of re-examination in view of the potential of bilirubin as a CNS toxin. Early discharge of newborns from the hospital has significantly altered diagnostic and therapeutic management of neonatal jaundice, transforming it into an outpatient problem. This transformation raises new questions regarding the best time to ascertain the cause(s) of jaundice and to identify risk factors to insure optimal management of the infant. Review of the current state of knowledge of bilirubin metabolism focused on new methods for measurement of unconjugated and conjugated bilirubin, measurement of bilirubin synthesis rates, the molecular biology of bilirubin conjugation and the developmental role of the family of enzymes known as glucuronyl transferase(s), and the role of genetic and other host factors in determining the safety or toxicity of bilirubin in the newborn.


2018 ◽  
Vol 26 (4) ◽  
pp. 433-443
Author(s):  
Xiaohui Li ◽  
Anastasia Theisen ◽  
Chanran Seo ◽  
D. Scott Sibley

The purpose of this article is to evaluate the current state of studying resourcefulness among children and families and to propose future research directions. Five domains of studying resourcefulness were discussed in this article; these domains are positive outcomes of being resourceful on family members, definition of resourcefulness, assessments of resourcefulness, factors contributing to children’s resourcefulness, and the programs aimed at increasing resourcefulness. By reviewing findings of the existing studies, this article revealed that resourcefulness is a multifaceted concept that has caused variations in the definitions/emphases from different scholars and the various existing scales testing different facets of the concept. While most of the studies focused on family members, none of them discussed the value of family resourcefulness in their studies. Research findings suggest that both environmental influences and personal characteristics contribute to children’s resourcefulness, which either directly or inexplicitly reflect the notions of family systems theory. Several resourcefulness intervention programs were identified, but these programs were mainly focused on children and socioeconomically disadvantaged families and all serve different purposes. We propose to generate matched programs for either parents or kids to enhance the outcome of these programs in the family settings. Future studies on consolidating the various definitions, scales, and programs on resourcefulness and family resourcefulness, as well as expanding understandings of the internal and external influences that contribute to a family’s resourcefulness from the systemic perspective are needed.



2019 ◽  
Vol 22 (2) ◽  
pp. 27-32
Author(s):  
Khurshida Tillahodjaeva ◽  

In this article we will talk about the scale of family and marriage relations in the early XX century in the Turkestan region, their regulation, legislation. Clearly reveals the role of women and men in the family, the definition of which is based on the material conditions of society, equality of rights and freedoms and its features.



Author(s):  
Sam A. Hardy ◽  
David C. Dollahite ◽  
Chayce R. Baldwin

The purpose of this chapter is to review research on the role of religion in moral development within the family. We first present a model of the processes involved. Parent or family religiosity is the most distal predictor and affects moral development through its influence on parenting as well as child or adolescent religiosity. Additionally, parenting affects moral development directly, but also through its influence on child or adolescent religiosity. In other words, parent or family religiosity dynamically interconnects with parenting styles and practices, and with family relationships, and these in turn influence moral development directly as well as through child or adolescent religiosity. We also discuss how these processes might vary across faith traditions and cultures, and point to directions for future research.



Buildings ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 29
Author(s):  
Ning Gu ◽  
Peiman Amini Behbahani

Computational creativity in built environment (BE) design has been a subject of research interest in the discipline. This paper presents a critical review of various ways computational creativity has been and can be defined and approached in BE design. The paper examines a comprehensive body of contemporary literature on the topics of creativity, computational creativity, and their assessment to identify levels of computational creativity. The paper then proceeds to a further review of the implications of these levels specifically in BE design. The paper identifies four areas in BE design where computational creativity is relevant. In two areas—synthesis (generation) and analysis—there is considerable literature on lower levels of computational creativity. However, in two other areas—interfacing and communication—even the definition of computational creativity is not as defined and clear for the discipline, and most works only consider the role of computers as a supporting tool or medium. These open up future research opportunities for the discipline.



2021 ◽  
pp. 112972982198916
Author(s):  
Ton Van Boxtel ◽  
Mauro Pittiruti ◽  
Annemarie Arkema ◽  
Patrick Ball ◽  
Giovanni Barone ◽  
...  

The need for filtering intravenous infusions has long been recognized in the field of venous access, though hard scientific evidence about the actual indications for in-line filters has been scarce. In the last few years, several papers and a few clinical studies have raised again this issue, suggesting that the time has come for a proper definition of the type of filtration, of its potential benefit, and of its proper indications in clinical practice. The WoCoVA Foundation, whose goal is to increase the global awareness on the risk of intravenous access and on patients’ safety, developed the project of a consensus on intravenous filtration. A panel of experts in different aspects of intravenous infusion was chosen to express the current state of knowledge about filtration and to indicate the direction of future research in this field. The present document reports the final conclusions of the panel.



2021 ◽  
Vol 22 (15) ◽  
pp. 7942
Author(s):  
Chiara Agrati ◽  
Alessandra Sacchi ◽  
Eleonora Tartaglia ◽  
Alessandra Vergori ◽  
Roberta Gagliardini ◽  
...  

In severe COVID-19, which is characterized by blood clots and neutrophil-platelet aggregates in the circulating blood and different tissues, an increased incidence of cardiovascular complications and venous thrombotic events has been reported. The inflammatory storm that characterizes severe infections may act as a driver capable of profoundly disrupting the complex interplay between platelets, endothelium, and leukocytes, thus contributing to the definition of COVID-19-associated coagulopathy. In this frame, P-selectin represents a key molecule expressed on endothelial cells and on activated platelets, and contributes to endothelial activation, leucocyte recruitment, rolling, and tissue migration. Briefly, we describe the current state of knowledge about P-selectin involvement in COVID-19 pathogenesis, its possible use as a severity marker and as a target for host-directed therapeutic intervention.



2009 ◽  
Vol 90 (2) ◽  
pp. 227-230 ◽  
Author(s):  
Joan Beder

When an individual dies, the role of the family member(s) is clearly prescribed by society: support, presence, caring, and remembrance. Traditionally, the definition of “family” has broadened to create the “extended family” or “expanded family” with members defined by deep bonds, relationships, and friendships. Currently, close friends who become the extended/expanded family, can be as central as kin to family structure and stability. Therefore, when one member of an extended family dies, the death resonates throughout the entire system affecting not only the lives of the immediate family members, but also those in the expanded circle of family relationships. This article describes the relationships in one extended family and discusses the struggles and counseling interventions used when one member of an extended family suddenly dies.



2011 ◽  
Vol 21 (3) ◽  
pp. 88-95 ◽  
Author(s):  
Deryk S. Beal

We are amassing information about the role of the brain in speech production and the potential neural limitations that coincide with developmental stuttering at a fast rate. As such, it is difficult for many clinician-scientists who are interested in the neural correlates of stuttering to stay informed of the current state of the field. In this paper, I aim to inspire clinician-scientists to tackle hypothesis-driven research that is grounded in neurobiological theory. To this end, I will review the neuroanatomical structures, and their functions, which are implicated in speech production and then describe the relevant differences identified in these structures in people who stutter relative to their fluently speaking peers. I will conclude the paper with suggestions on directions of future research to facilitate the evolution of the field of neuroimaging of stuttering.



2021 ◽  

Many contemporary party organizations are failing to fulfill their representational role in contemporary democracies. While political scientists tend to rely on a minimalist definition of political parties (groups of candidates that compete in elections), this volume argues that this misses how parties can differ not only in degree but also in kind. With a new typology of political parties, the authors provide a new analytical tool to address the role of political parties in democratic functioning and political representation. The empirical chapters apply the conceptual framework to analyze seventeen parties across Latin America. The authors are established scholars expert in comparative politics and in the cases included in the volume. The book sets an agenda for future research on parties and representation, and it will appeal to those concerned with the challenges of consolidating stable and programmatic party systems in developing democracies.



Author(s):  
Linda McDowell

Divisions based on the assumption that men and women are different from one another permeate all areas of social life as well as varying across space and between places. In the home and in the family, in the classroom or in the labour market, in politics, and in power relations, men and women are assumed to be different, to have distinct rights and obligations that affect their daily lives and their standard of living. Thirty years ago, there were no courses about gender in British geography departments. This chapter discusses the challenges to geographical knowledge, and to the definition of knowledge more generally, that have arisen from critical debates about the meaning of difference and diversity in feminist scholarship. It examines a number of significant conceptual ideas, namely: the public and the private; sex, gender and body; difference, identity and intersectionality; knowledge; and justice. Finally, it comments on the role of feminism in the academy as a set of political practices as well as epistemological claims.



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