WoCoVA consensus on the clinical use of in-line filtration during intravenous infusions: Current evidence and recommendations for future research

2021 ◽  
pp. 112972982198916
Author(s):  
Ton Van Boxtel ◽  
Mauro Pittiruti ◽  
Annemarie Arkema ◽  
Patrick Ball ◽  
Giovanni Barone ◽  
...  

The need for filtering intravenous infusions has long been recognized in the field of venous access, though hard scientific evidence about the actual indications for in-line filters has been scarce. In the last few years, several papers and a few clinical studies have raised again this issue, suggesting that the time has come for a proper definition of the type of filtration, of its potential benefit, and of its proper indications in clinical practice. The WoCoVA Foundation, whose goal is to increase the global awareness on the risk of intravenous access and on patients’ safety, developed the project of a consensus on intravenous filtration. A panel of experts in different aspects of intravenous infusion was chosen to express the current state of knowledge about filtration and to indicate the direction of future research in this field. The present document reports the final conclusions of the panel.

2020 ◽  
pp. 112972982092456 ◽  
Author(s):  
Fulvio Pinelli ◽  
Mauro Pittiruti ◽  
Ton Van Boxtel ◽  
Giovanni Barone ◽  
Roberto Biffi ◽  
...  

Background: Subcutaneously anchored securement devices (or subcutaneous engineered securement devices) have been introduced recently into the clinical practice, but the number of published studies is still scarce. The Italian Group of Long-Term Central Venous Access Devices (GAVeCeLT)—in collaboration with WoCoVA (World Congress on Vascular Access)—has developed a Consensus about the effectiveness, safety, and cost-effectiveness of such devices. Methods: After the definition of a panel of experts, a systematic collection and review of the literature on subcutaneously anchored securement devices was performed. The panel has been divided in two working groups, one focusing on adult patients and the other on children and neonates. Results: Although the quality of evidence is generally poor, since it is based mainly on non-controlled prospective studies, the panel has concluded that subcutaneously anchored securement devices are overall effective in reducing the risk of dislodgment and they appear to be safe in all categories of patients, being associated only with rare and negligible local adverse effects; cost-effectiveness is demonstrated—or highly likely—in specific populations of patients with long-term venous access and/or at high risk of dislodgment. Conclusion: Subcutaneously anchored securement is a very promising strategy for avoiding dislodgment. Further studies are warranted, in particular for the purpose of defining (a) the best management of the anchoring device so to avoid local problems, (b) the patient populations in which it may be considered highly cost-effective and even mandatory, (c) the possible benefit in terms of reduction of other catheter-related complications such as venous thrombosis and/or infection, and—last but not least—(d) their impact on the workload and stress level of nurses taking care of the devices.


Author(s):  
Jessica M. Brooks ◽  
Kanako Iwanaga ◽  
Fong Chan

Arthritis is ranked among the top causes of disability in the United States and worldwide. Despite recent improvements in medications and medical treatment, there is no known cure for arthritis. Providing evidence-based psychoeducation and counseling services to people with arthritis lessens the impact of pain-related symptoms and disability on the individual and society. The purpose of this chapter is to provide an overview of the most common arthritic conditions, co-occurring physical conditions, and psychosocial factors associated with arthritis. Barriers to self-management and existing self-management programs are also discussed along with the current state of scientific evidence. The chapter concludes with some questions for future research.


Author(s):  
Cristina Barboza-Solís DDS, MSc, PhD ◽  
Luis Alberto Acuña-Amador PhD

In recent decades, a body of literature examining the relationships between oral health and general health has rapidly developed. However, the biological mechanisms involved in explaining such relationships have not been fully described. Recent evidence has suggested that these relationships could be partially explained by the composition and interaction of the microbiome/microbiota between local and systemic body sites. For instance, it has been suggested that intestinal microbiota could have effects on non-communicable diseases, such as diabetes or cardiovascular diseases. The objective of this study is to explore current evidence of the link between oral and systemic diseases, to discuss whether oral microbiome/microbiota could represent an unexplored biological pathway partially explaining those relationships. A non-systematic review of the literature was carried out using keyword searches in Pubmed from February to May 2019. The ultimate goal was to present recent scientific evidence to update the general knowledge on this topic to professionals in dentistry. This review is divided in two parts for journal publication; however, it is intended to be used as one piece. In this first part, we will summarize the conceptual background of oral microbiome/microbiota, we will describe the main methods used in microbiology to characterize oral organisms, and will present the main composition of bacteria in oral microbiome/microbiota. The second part highlights the main evidence regarding the biological plausibility that links oral microbiome and systemic diseases and we will conclude with some future research recommendations. Taking into account the role of oral microbiota in the development of systemic diseases could change the main paradigm of how oral health is currently conceptualized by dental professionals.


Retos ◽  
2019 ◽  
pp. 597-603
Author(s):  
Carlos Bermudez Torres ◽  
Pedro Saenz-López

Las evidencias científicas de la importancia de las emociones en el ámbito educativo son cada vez mayores y más concluyentes. Así, se ha realizado una investigación teniendo como principal objetivo conocer el estado de la educación emocional en el área de la Educación Física. Para ello, a través de una revisión sistemática, se ha buscado en la base de datos Web Of Science, donde se han seleccionado 21 artículos, comprendidos entre 2015-2017 a través de criterios de inclusión acorde a los objetivos planteados. Estos artículos seleccionados se han analizado para su posterior categorización y obtención de los resultados. Estos últimos indican que se han realizado más investigaciones dedicadas a los alumnos que a los docentes, además se ha tratado en mayor medida la educación emocional como un fin que como un medio o en relación con otras variables. Finalmente, se propone futuras líneas de investigación y aplicaciones prácticas para los docentes.Abstract. Scientific evidence on the importance of emotions in the educational context is growing and becoming more conclusive. These investigation has been carried out with the main objective of knowing the current state of Emotional Education in the area of Physical Education. A total of 21 articles published between 2015 and 2017 were selected according to the inclusion criteria of our objectives, after a systematic review of works in the Web of Science database. These articles were analysed and successively categorized to extrapolate results. These indicate that research in the field has focused more on students than on teachers; additionally, emotional education has been treated as a target rather than as a mean, or rather than studying its relation with other variables. Finally, future research lines and practical applications for teachers are suggested.


2022 ◽  
Vol 15 ◽  
Author(s):  
Thenille Braun Janzen ◽  
Yuko Koshimori ◽  
Nicole M. Richard ◽  
Michael H. Thaut

Research in basic and clinical neuroscience of music conducted over the past decades has begun to uncover music’s high potential as a tool for rehabilitation. Advances in our understanding of how music engages parallel brain networks underpinning sensory and motor processes, arousal, reward, and affective regulation, have laid a sound neuroscientific foundation for the development of theory-driven music interventions that have been systematically tested in clinical settings. Of particular significance in the context of motor rehabilitation is the notion that musical rhythms can entrain movement patterns in patients with movement-related disorders, serving as a continuous time reference that can help regulate movement timing and pace. To date, a significant number of clinical and experimental studies have tested the application of rhythm- and music-based interventions to improve motor functions following central nervous injury and/or degeneration. The goal of this review is to appraise the current state of knowledge on the effectiveness of music and rhythm to modulate movement spatiotemporal patterns and restore motor function. By organizing and providing a critical appraisal of a large body of research, we hope to provide a revised framework for future research on the effectiveness of rhythm- and music-based interventions to restore and (re)train motor function.


2013 ◽  
Vol 137 (12) ◽  
pp. 1822-1824 ◽  
Author(s):  
Kirk D. Jones

The term lepidic is used prominently in the recently published multidisciplinary classification of adenocarcinoma. The lack of use in common (nonmedical) English has led to some confusion over the proper definition of this term. This historical perspective traces the history of the term lepidic from its origins at McGill University in Montreal, Canada, through its uses in English pathologic descriptions, to its current state in pulmonary pathology.


PEDIATRICS ◽  
1994 ◽  
Vol 94 (4) ◽  
pp. 537-540
Author(s):  
Lawrence M. Gartner ◽  
Charlotte S. Catz ◽  
Sumner J. Yaffe

A neonatal bilirubin workshop took place at The Rockefeller University on June 20 through 22, 1993 to consider controversial issues in the field of neonatal jaundice and bilirubin neurotoxicity, particularly as they relate to management. The conference was sponsored by the National Institute of Child Health and Human Development (Pregnancy and Perinatology Branch, Center for Mothers and Children), The Rockefeller University, and the Consiglio Nazionale delle Richerche (Italy). tk;4Presentations and discussion emphasized diagnosis, biochemistry, and mechanisms of bilirubin toxicity, the definition and consequences of kernicterus, and the appropriateness and safety of the various therapies currently in use. Identification of future research needs was an important agenda item. The conferees agreed that conventional management of jaundice in the newborn with phototherapy and exchange transfusion, as well as with phenobarbital in certain situations, had significantly reduced the occurrence of "traditional" kernicterus. However, the conferees acknowledged that the classical definition of kernicterus was in need of re-examination in view of the potential of bilirubin as a CNS toxin. Early discharge of newborns from the hospital has significantly altered diagnostic and therapeutic management of neonatal jaundice, transforming it into an outpatient problem. This transformation raises new questions regarding the best time to ascertain the cause(s) of jaundice and to identify risk factors to insure optimal management of the infant. Review of the current state of knowledge of bilirubin metabolism focused on new methods for measurement of unconjugated and conjugated bilirubin, measurement of bilirubin synthesis rates, the molecular biology of bilirubin conjugation and the developmental role of the family of enzymes known as glucuronyl transferase(s), and the role of genetic and other host factors in determining the safety or toxicity of bilirubin in the newborn.


Author(s):  
Pankaj ◽  
Micki Hyde ◽  
Arkalgud Ramaprasad ◽  
Suresh K. Tadisina

There is no systematic study of Information Systems (IS) agility in academic and practitioner IS literature and the concept is not well defined. For rigorous academic studies of IS agility, a proper definition/conceptualization of IS agility is needed. To fulfill this objective, existing published work on agility is analyzed. The analysis demonstrates that the existing definitions may need improvement to aid in arriving at a definition of IS agility. A new definition of agility that captures its core properties is proposed. The advantages of this definition over existing definitions is demonstrated and it is used to define IS Agility. Salient features of an agile IS are discussed and the utility of the proposed definition in arriving at attributes of an agile IS is demonstrated. Efficacy and validity of the proposed definition is demonstrated through interviews with IS executives from a diverse organization set. Lastly, avenues for future research are proposed.


Hand ◽  
2019 ◽  
Vol 15 (6) ◽  
pp. 761-770
Author(s):  
Annie M. Q. Wang ◽  
Min Kim ◽  
Emily S. Ho ◽  
Kristen M. Davidge

Camptodactyly is a pediatric hand condition, the treatment of which remains controversial. The authors’ aim was to improve patient care through clarifying the definition of camptodactyly and indications for surgical and/or conservative management, summarizing outcomes, and defining risks. A systematic review was conducted of articles in all languages on outcomes following surgical and/or conservative management of idiopathic camptodactyly in children using MEDLINE (Medical Literature Analysis and Retrieval System Online), PubMed, EMBASE (Excerpta Medica database), AMED (Allied and Complementary Medicine), and CINAHL (Cumulative Index of Nursing and Allied Health Literature) (until January 2017). The primary outcome was posttreatment flexion contracture, and the secondary outcomes were indications for surgery, complications, and patient satisfaction. Database searching generated 16 final articles, with 7 case series and 9 retrospective cohort studies. There was a lack of consistency on the definition of camptodactyly and in outcome reporting. All 16 studies received a “Weak” global rating and demonstrated low-quality evidence, suggesting that treatment of camptodactyly with operative or nonoperative measures reduces the degree of flexion contracture in most patients (from pretreatment averages of 20°-85° to posttreatment averages of 5°-37°). There was general agreement that surgery should be reserved for contracture >30° or failure to respond to conservative management. Surgery generally led to more complications compared with conservative management. Only one study reported on functional limitations, and another reported on patient-reported outcomes. Current evidence of the effectiveness of camptodactyly treatment in addressing both joint-specific deformity and patient-perceived function and appearance is insufficient to guide patient care. Future research may consider the development of decision aids to guide patients and families through selecting management strategies and to promote shared decision making.


Sports ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 141
Author(s):  
Rudy N. Kalema ◽  
Anthony G. Schache ◽  
Morgan D. Williams ◽  
Bryan Heiderscheit ◽  
Gabriel Siqueira Trajano ◽  
...  

Hamstring strain injury (HSI) is a common and costly injury in many sports such as the various professional football codes. Most HSIs have been reported to occur during high intensity sprinting actions. This observation has led to the suggestion that a link between sprinting biomechanics and HSIs may exist. The aim of this literature review was to evaluate the available scientific evidence underpinning the potential link between sprinting biomechanics and HSIs. A structured search of the literature was completed followed by a risk of bias assessment. A total of eighteen studies were retrieved. Sixteen studies involved retrospective and/or prospective analyses, of which only three were judged to have a low risk of bias. Two other case studies captured data before and after an acute HSI. A range of biomechanical variables have been measured, including ground reaction forces, trunk and lower-limb joint angles, hip and knee joint moments and powers, hamstring muscle–tendon unit stretch, and surface electromyographic activity from various trunk and thigh muscles. Overall, current evidence was unable to provide a clear and nonconflicting perspective on the potential link between sprinting biomechanics and HSIs. Nevertheless, some interesting findings were revealed, which hopefully will stimulate future research on this topic.


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