scholarly journals Active Targeted Nanoparticles for Anti Cancer Nano Drugs Delivery across the Blood Brain Barrier for Human Brain Cancer Treatment, Multiple Sclerosis (MS) and Alzheimer's Diseases Using Chemical Modifications of Anti– Cancer Nano Drugs or Drug– Nanoparticles through Zika Virus (ZIKV) Nanocarriers under Synchrotron Radiation

2017 ◽  
Vol 2 (2) ◽  
pp. 90-94 ◽  
Author(s):  
Alireza Heidari ◽  
Keyword(s):  
Multiple Sclerosis ◽  
Synchrotron Radiation ◽  
Human Brain ◽  
Cancer Treatment ◽  
Brain Cancer ◽  
Zika Virus ◽  
Chemical Modifications ◽  
Targeted Nanoparticles ◽  
Drug Nanoparticles ◽  
Anti Cancer

scholarly journals A review on nutraceuticals: A healthy way to treat brain cancer

2021 ◽  
Vol 15 (3) ◽  
pp. 335-348
Author(s):  
Samiksha Marotrao Nikam ◽  
Yash Rajkumar Menghani ◽  
Millind Janraoji Umekar
Keyword(s):  
Side Effects ◽  
Disease Prevention ◽  
Cancer Treatment ◽  
Human Health ◽  
Cause Of Death ◽  
Brain Cancer ◽  
Good Health ◽  
Alternative Approach ◽  
Anti Cancer ◽  
Health And Disease

A Balanced body is important for good health and for balancing the state of body, healthy food is necessary. Cancer is the uncontrolled growth of cells which upon time worsen and turns into tumor and as it is a leading cause of death worldwide, it is so important to research and find alternative treatments for the management of cancer. Nutraceuticals are known as alternative approach for the control of cancer. Nutraceuticals has many health benefits, and now known as the future of treatment for various health diseases. It has shown to elicit anti-aging, anti-cancer and other health enhancing effects. Nutraceuticals also have significant promise in the promotion of human health and disease prevention. Since, the present cancer treatment has various side effects, the benefits of these nutraceuticals may result in approaches to improve human health in a alternate way. In this review, we highlighted the etiology, diagnosis, pathogenesis of brain cancer along with treatment by using nutraceuticals.

scholarly journals Hypoxia modulation by dual-drug nanoparticles for enhanced synergistic sonodynamic and starvation therapy

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Jingxue Wang ◽  
Ju Huang ◽  
Weichen Zhou ◽  
Jiawen Zhao ◽  
Qi Peng ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Contrast Agents ◽  
Therapeutic Effects ◽  
Non Invasive ◽  
Drug Nanoparticles ◽  
Theranostic Nanoparticles ◽  
Anti Cancer ◽  
Therapy Strategies ◽  
Cancer Theranostics ◽  
Dual Drug

Abstract Background Sonodynamic therapy (SDT) is an emerging non-invasive therapeutic technique. SDT-based cancer therapy strategies are presently underway, and it may be perceived as a promising approach to improve the efficiency of anti-cancer treatment. In this work, multifunctional theranostic nanoparticles (NPs) were synthesized for synergistic starvation therapy and SDT by loading glucose oxidase (GOx, termed G) and 5,10,15,20-tetrakis (4-chlorophenyl) porphyrin) Cl (T (p-Cl) PPMnCl, termed PMnC) in Poly (lactic-co-glycolic) acid (PLGA) NPs (designated as MG@P NPs). Results On account of the peroxidase-like activity of PMnC, MG@P NPs can catalyze hydrogen peroxide (H2O2) in tumor regions to produce oxygen (O2), thus enhancing synergistic therapeutic effects by accelerating the decomposition of glucose and promoting the production of cytotoxic singlet oxygen (1O2) induced by ultrasound (US) irradiation. Furthermore, the NPs can also serve as excellent photoacoustic (PA)/magnetic resonance (MR) imaging contrast agents, effectuating imaging-guided cancer treatment. Conclusion Multifunctional MG@P NPs can effectuate the synergistic amplification effect of cancer starvation therapy and SDT by hypoxia modulation, and act as contrast agents to enhance MR/PA dual-modal imaging. Consequently, MG@P NPs might be a promising nano-platform for highly efficient cancer theranostics. Graphical Abstract

scholarly journals Hypoxia Modulation by Dual-drug Nanoparticles for Enhanced Synergistic Sonodynamic and Starvation Therapy

2020 ◽  
Author(s):  
Jingxue Wang ◽  
Ju Huang ◽  
Weichen Zhou ◽  
Jiawen Zhao ◽  
Peng Qi ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Contrast Agents ◽  
Therapeutic Effects ◽  
Non Invasive ◽  
Drug Nanoparticles ◽  
Theranostic Nanoparticles ◽  
Anti Cancer ◽  
Therapy Strategies ◽  
Cancer Theranostics ◽  
Dual Drug

Abstract Background: Sonodynamic therapy (SDT) is an emerging non-invasive therapeutic technique. SDT-based cancer therapy strategies are presently underway, and it may be perceived as a promising approach to improve the efficiency of anti-cancer treatment. In this work, multifunctional theranostic nanoparticles (NPs) were synthesized for synergistic starvation therapy and SDT by loading glucose oxidase (GOx, termed G) and 5,10,15,20-tetrakis (4-chlorophenyl) porphyrin) Cl (T (p-Cl) PPMnCl, termed PMnC) in Poly (lactic-co-glycolic) acid (PLGA) NPs (designated as MG@P NPs). Results: On account of the peroxidase-like activity of PMnC, MG@P NPs can catalyze hydrogen peroxide (H2O2) in tumor regions to produce oxygen (O2), thus enhancing synergistic therapeutic effects by accelerating the decomposition of glucose and promoting the production of cytotoxic singlet oxygen (1O2) induced by ultrasound (US) irradiation. Furthermore, the NPs can also serve as excellent photoacoustic (PA)/magnetic resonance (MR) imaging contrast agents, effectuating imaging-guided cancer treatment. Conclusion: Multifunctional MG@P NPs can effectuate the synergistic amplification effect of cancer starvation therapy and SDT by hypoxia modulation, and act as contrast agents to enhance MR/PA dual-modal imaging. Consequently, MG@P NPs might be a promising nano-platform for highly efficient cancer theranostics.

Theranostic Potential of Targeted Nanoparticles for Brain Cancer

2017 ◽  
Vol 17 (18) ◽  
Author(s):  
Ajita Bhatt ◽  
Ekta Gurnany ◽  
Anuj Modi ◽  
Arvind Gulbake ◽  
Aviral Jain
Keyword(s):  
Brain Cancer ◽  
Targeted Nanoparticles
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