Coarsening of Cobalt Precipitates in Copper- Cobalt Alloys

1982 ◽  
Vol 21 ◽  
Author(s):  
T. Eguchi ◽  
Y. Tomokiyo ◽  
K. Oki ◽  
Y. Seno

ABSTRACTThe Ostwald ripening of precipitates in Cu-Co alloys was investigated by electron microscopic observation. The variation of the mean particle radius r, and the distribution of relative particle sizes, f(r/r) , were obtained as functions of the aging time at 873K . The shape of f(r/r)was rather sharp and symmetrical around r = T in the early stage. It became broad with the aging and was similar, in the late stage, to the theoretical distribution of Ardell. It appeared that the shape of f(r/r) depends on the volume fraction but the growth rate of F scarcely depends on it. The rate of change of r was proportional to the cube root of the aging time from the early stage of aging.

2021 ◽  
Vol 9 ◽  
Author(s):  
Qian Zhao ◽  
Baochun Huang ◽  
Zhiyu Yi ◽  
Pengfei Xue

Paleocene carbonates from the Gamba area of South Tibet provide the largest paleomagnetic dataset for constraining the paleogeography of the India-Asia collision in the early stage. Previous studies argued that the characteristic remanences (ChRMs) obtained from this unit were remagnetized via orogenic fluids. This study carries out a high-resolution petrographic study on the Paleocene carbonates from Gamba aiming to test the nature of the ChRMs. Electron microscopic observation on magnetic extracts identified a large amount of detrital magnetite that are multi- to single domain in sizes and nanoscale biogenic magnetite. Minor framboidal iron oxides were also identified, which were previously interpreted as authigenic magnetite that substitutes pyrite. However, our scanning and transmission electron microscopic (SEM/TEM) observations, along with optical microscope and Raman spectrum investigations further suggest that these magnetic minerals are pigmentary hematite and goethite that are incapable of carrying a stable primary magnetization. We therefore argue that the ChRMs of the limestones from the Zongpu Formation in the Gamba area are carried by detrital and biogenic magnetites rather than authigenic magnetite. The paleomagnetic data from the Gamba area are interpreted as primary origin and can thus be used for tectonic reconstructions. We emphasize that magnetic extraction, integrated with advanced mineralogic studies (e.g., electron backscatter diffraction and electron diffraction) are effective approaches for investigating the origin of magnetic carriers in carbonate rocks.


2004 ◽  
Vol 165 (5) ◽  
pp. 663-671 ◽  
Author(s):  
Kumi Matsuura ◽  
Paul A. Lefebvre ◽  
Ritsu Kamiya ◽  
Masafumi Hirono

How centrioles and basal bodies assemble is a long-standing puzzle in cell biology. To address this problem, we analyzed a novel basal body-defective Chlamydomonas reinhardtii mutant isolated from a collection of flagella-less mutants. This mutant, bld10, displayed disorganized mitotic spindles and cytoplasmic microtubules, resulting in abnormal cell division and slow growth. Electron microscopic observation suggested that bld10 cells totally lack basal bodies. The product of the BLD10 gene (Bld10p) was found to be a novel coiled-coil protein of 170 kD. Immunoelectron microscopy localizes Bld10p to the cartwheel, a structure with ninefold rotational symmetry positioned near the proximal end of the basal bodies. Because the cartwheel forms the base from which the triplet microtubules elongate, we suggest that Bld10p plays an essential role in an early stage of basal body assembly. A viable mutant having such a severe basal body defect emphasizes the usefulness of Chlamydomonas in studying the mechanism of basal body/centriole assembly by using a variety of mutants.


2004 ◽  
Vol 449-452 ◽  
pp. 521-524
Author(s):  
T. Maebashi ◽  
Minoru Doi ◽  
Takao Kozakai

The morphological changes and the coarsening kinetics of B2 particles in A2 matrix in the elastically constrained Fe-16at%Al-18at%Co alloy were investigated by means of transmission electron microscopy (TEM). The mean particle radius increases in proportion to the cube root of ageing time at early stage, then the coarsening of B2 particle decelerate at late stage of aging. And it clarified the decelerated coarsening in Fe based alloy also is related to the change in PSD and is caused by the elastically strained effect.


2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Shutian Zhang ◽  
Li Hu ◽  
Jialun Jiang ◽  
Hongji Li ◽  
Qin Wu ◽  
...  

Abstract Background Microglial mediated neuroinflammation in the rostral ventrolateral medulla (RVLM) plays roles in the etiology of stress-induced hypertension (SIH). It was reported that autophagy influenced inflammation via immunophenotypic switching of microglia. High-mobility group box 1 (HMGB1) acts as a regulator of autophagy and initiates the production of proinflammatory cytokines (PICs), but the underlying mechanisms remain unclear. Methods The stressed mice were subjected to intermittent electric foot shocks plus noises administered for 2 h twice daily for 15 consecutive days. In mice, blood pressure (BP) and renal sympathetic nerve activity (RSNA) were monitored by noninvasive tail-cuff method and platinum-iridium electrodes placed respectively. Microinjection of siRNA-HMGB1 (siHMGB1) into the RVLM of mice to study the effect of HMGB1 on microglia M1 activation was done. mRFP-GFP-tandem fluorescent LC3 (tf-LC3) vectors were transfected into the RVLM to evaluate the process of autolysosome formation/autophagy flux. The expression of RAB7, lysosomal-associated membrane protein 1 (LAMP1), and lysosomal pH change were used to evaluate lysosomal function in microglia. Mitophagy was identified by transmission electron microscopic observation or by checking LC3 and MitoTracker colocalization under a confocal microscope. Results We showed chronic stress increased cytoplasmic translocations of HMGB1 and upregulation of its receptor RAGE expression in microglia. The mitochondria injury, oxidative stress, and M1 polarization were attenuated in the RVLM of stressed Cre-CX3CR1/RAGEfl/fl mice. The HMGB1/RAGE axis increased at the early stage of stress-induced mitophagy flux while impairing the late stages of mitophagy flux in microglia, as revealed by decreased GFP fluorescence quenching of GFP-RFP-LC3-II puncta and decreased colocalization of lysosomes with mitochondria. The expressions of RAB7 and LAMP1 were decreased in the stressed microglia, while knockout of RAGE reversed these effects and caused an increase in acidity of lysosomes. siHMGB1 in the RVLM resulted in BP lowering and RSNA decreasing in SIH mice. When the autophagy inducer, rapamycin, is used to facilitate the mitophagy flux, this treatment results in attenuated NF-κB activation and reduced PIC release in exogenous disulfide HMGB1 (ds-HMGB1)-stimulated microglia. Conclusions Collectively, we demonstrated that inhibition of the HMGB1/RAGE axis activation led to increased stress-induced mitophagy flux, hence reducing the activity of microglia-mediated neuroinflammation and consequently reduced the sympathetic vasoconstriction drive in the RVLM.


1989 ◽  
Vol 26 (3) ◽  
pp. 664-670 ◽  
Author(s):  
Douglas W. Cooper

This particular three-dimensional random packing limit problem is to determine the mean fraction of a cubic space that would be occupied by aligned, fixed, equalsize cubes, placed at random locations sequentially until no more can be added. No analytical solution has yet been found for this problem. Simulation results for a finite region and finite number of attempts were extrapolated to an infinite number of attempts (N →∞) in an infinite region by multiple linear regression, using volume fraction occupied (F) as a linear combination of the ratio of the length of the small cube sides (S) to the length of the cubic region side (L) and the cube root of the ratio of the region volume to the total volume of cubes tried, (L3/NS3)⅓. These results for random packing in a volume with penetrable walls can be adjusted with a multiplicative correction factor to give the results for impenetrable walls. A total of N = 107 attempts at placement were made for L/S = 20/1 and N = 14 × 106 attempts were made for L/S = 10/1. The results for volume fraction packed are correlated by F = 0.430(±0.008) + 0.966(±0.072)(S/L) – 0.236(±0.029)(L3/NS)⅓. The numbers in parentheses are twice the standard errors of estimate of the coefficients, indicating the 95% confidence intervals due to random errors. This value for the packing density limit, 0.430 ± 0.008, is slightly larger than that given by a conjecture by Palásti [10], 0.4178. Our value is consistent with that obtained by rather different simulation methods by Jodrey and Tory [8], 0.4227 ± 0.0006, and by Blaisdell and Solomon [2], 0.4262.


2011 ◽  
Vol 120 (11) ◽  
pp. 713-721 ◽  
Author(s):  
Takehisa Saito ◽  
Tetsufumi Ito ◽  
Norihiko Narita ◽  
Takechiyo Yamada ◽  
Yasuhiro Manabe

Objectives: The aim of this study was to evaluate the mean number of regenerated fungiform taste buds per papilla and perform light and electron microscopic observation of taste buds in patients with recovered taste function after severing the chorda tympani nerve during middle ear surgery. Methods: We performed a biopsy on the fungiform papillae (FP) in the midlateral region of the dorsal surface of the tongue from 5 control volunteers (33 total FP) and from 7 and 5 patients with and without taste recovery (34 and 29 FP, respectively) 3 years 6 months to 18 years after surgery. The specimens were observed by light and transmission electron microscopy. The taste function was evaluated by electrogustometry. Results: The mean number of taste buds in the FP of patients with completely recovered taste function was significantly smaller (1.9 ± 1.4 per papilla; p < 0.01) than that of the control subjects (3.8 ± 2.2 per papilla). By transmission electron microscopy, 4 distinct types of cell (type I, II, III, and basal cells) were identified in the regenerated taste buds. Nerve fibers and nerve terminals were also found in the taste buds. Conclusions: It was clarified that taste buds containing taste cells and nerve endings do regenerate in the FP of patients with recovered taste function.


2014 ◽  
Vol 1028 ◽  
pp. 14-19 ◽  
Author(s):  
Hai Jun Wu ◽  
Xiao Qing Zuo ◽  
Ying Wu Wang ◽  
Kun Hua Zhang ◽  
Yu Zeng Chen

Pd-Ag-Sn-In-Zn alloy was subjected to isothermal aging treatments at 400°C, 500°C, and 650°C. Age-hardening behaviour and related microstructure changes of the aged alloy were studied by means of hardness test, X-ray diffraction (XRD), scanning electron microscopic (SEM) and energy dispersive spectrometer (EDS). The results indicate that the hardness of the alloy reaches a highest value of 348Hv after aging at 650°C for 20min. Further increasing the aging time leads to softening. The hardening of the alloy at early stage of the age-hardening at 650°C is ascribed to the formation of lamellar (α1+ β) precipitates along the grain boundaries of α matrix. The softening of the alloy occurred by further increasing aging time is caused by the coarsening of the precipitates.


Haigan ◽  
1988 ◽  
Vol 28 (3) ◽  
pp. 303-311
Author(s):  
Tadashi Imai ◽  
Yasuki Saito ◽  
Noriyuki Nagamoto ◽  
Masami Sato ◽  
Keiji Kanma ◽  
...  

2002 ◽  
Vol 738 ◽  
Author(s):  
S. Ichikawa ◽  
K. Okazaki ◽  
T. Akita ◽  
M. Okumura ◽  
K. Tanaka ◽  
...  

ABSTRACTThe size dependence of the catalytic property of the gold catalysts has been reported. It is especially interesting that the catalytic property of gold suddenly changes to show a platinum-like behavior when the mean size of gold is below 2nm. This phenomenon should be owing to the change of the electronic structure of the gold, however its detail has not been cleared yet. We investigated the size dependence of the mean inner potential of gold catalysts supported on TiO2, which is affected by the outer valence electron, using electron holography and high-resolution electron microscopy. We found the following tendency. When the size of the gold particle is over 5nm, the values of the mean inner potential are the same level as the reported experimental values of the bulk gold (21–23V) and the calculated values of the bulk gold (25–30V). When the size is below 5nm, the mean inner potential begins to increase over 30V, and it begins to increase suddenly over 40V at the size below about 2nm. It indicates that the electronic structure of the gold particles varies from that of the bulk state as the size of the gold particles reduces. Due to the size reduction, the volume fraction of the surface atoms and the interface atoms increases, e.g., almost half of the atoms locate on the surfaces or at the interface in case of the top half of the octahedron particle with the size 1.6nm. The surface dipole and the interface dipole should be formed owing to the electron out of the surface to the vacuum and the local charge transfer from the gold particles to the TiO2 surface. These dipole effects might be effective and one of the reasons for the increase of the mean inner potential of gold particles.


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