Surface Modification Of Polymers With Grafting And Coating Of Silane Hybrids And Their Bioactivity

1999 ◽  
Vol 576 ◽  
Author(s):  
Masaaki Kubo ◽  
Seisuke Takashima ◽  
Kanji Tsuru ◽  
Satoshi Hayakawa ◽  
Akiyoshi Osaka ◽  
...  
Keyword(s):  
Contact Angle ◽  
High Density Polyethylene ◽  
Body Fluid ◽  
Chemical Species ◽  
Hydrated Silica ◽  
Bioactive Materials ◽  
Poly Vinyl Chloride ◽  
Essential Chemical ◽  
Surface Modified

ABSTRACTHydrated silica rich Si-OH and Si-0- groups serve in a body environment as sites for nucleation of apatite, and are known as an essential chemical species for bioactive materials. Organic polymers having surface modified with the hydrated silica will show bioactivity: bone tissues grow toward the apatite layer and bond to materials. Thus MOPS-M (3-methacryloxypropyltrimethoxysilane) was grafted under emulsion polymerization procedure to high density polyethylene (HDPE), poly (vinyl chloride) (PVC) and polyamide (PA) substrates to examine in vitro deposition of apatite (bioactivity) after soaking in a simulated body fluid (Kokubo solution). Bioactivity was confirmed for the grafted PVC and PA substrates and discussed in terms of contact angle and relative amount of grafted silane molecules.

scholarly journals In vitro apatite formation on organic polymers modified with a silane coupling reagent

2005 ◽  
Vol 2 (4) ◽  
pp. 335-340 ◽  
Author(s):  
Yuki Shirosaki ◽  
Masaaki Kubo ◽  
Seisuke Takashima ◽  
Kanji Tsuru ◽  
Satoshi Hayakawa ◽  
...  
Keyword(s):  
High Density Polyethylene ◽  
Body Fluid ◽  
Contact Angles ◽  
Organic Polymer ◽  
Apatite Formation ◽  
Distilled Water ◽  
Organic Polymers ◽  
Coupling Reagent ◽  
Silane Coupling

γ-Methacryloxypropyltrimethoxysilane (γ-MPS) was grafted to high-density polyethylene, polyamide and silicone rubber substrates by the emulsion polymerization procedure in order to provide these organic polymers with in vitro apatite-forming ability. The contact angles towards distilled water of the γ-MPS-grafted specimens were lower than those of the original organic polymer specimens, indicating that the grafted substrates were more hydrophilic. The in vitro apatite formation in a simulated body fluid (Kokubo solution) was confirmed for several of the γ-MPS-grafted specimens.

scholarly journals In Vitro Bioactivity of PMMA-co-EHA Composites Filled with SiO2-Free Glass

2008 ◽  
Vol 14 (S3) ◽  
pp. 37-38
Author(s):  
P.P. Lopes ◽  
B.J.M. Leite Ferreira ◽  
R.N. Correia ◽  
H.F.V. Fernandes
Keyword(s):  
Body Fluid ◽  
Medical Application ◽  
In Vitro Bioactivity ◽  
Bioactive Glasses ◽  
Bioactive Materials ◽  
Oh Groups ◽  
Titania Gel ◽  
Living Bone ◽  
Free Glass

Bioactive materials for potential medical application have inspired and stimulated new searches. It has been confirmed that bioactive glasses bond to living bone through an apatite layer that precipitates on their surface in physiological media. These glasses normally constituted by silica, where the silicon is the network former, induce apatite nucleation by the formation of Si-OH groups. The presence of OH groups seems to be of utmost importance in the bioactive behaviour of materials. It was revealed that even metals, such as pure titania gel can bond to bone, if previously subjected to alkali and heat treatments. In the present work a new composite with a Ca-P-Ti glass was synthesized and its in vitro bioactivity was studied in Kokubo's simulated body fluid. It is believed that the formation of Ti-OH groups on the glass can induce apatite precipitation on the composites surface.

In vitro mineralization of surface-modified porous polycaprolactone scaffolds in simulated body fluid

2008 ◽  
Vol 255 (2) ◽  
pp. 429-431 ◽  
Author(s):  
Chengyun Ning ◽  
Haimei Cheng ◽  
Wenjun Zhu ◽  
Zhaoyi Yin ◽  
Hao Chen ◽  
...  
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
In Vitro Mineralization ◽  
Surface Modified

A Study on the Bioactivity of Nano-Titania/Hydroxyapatite Composite

2006 ◽  
Vol 309-311 ◽  
pp. 411-414 ◽  
Author(s):  
Bang Cheng Yang ◽  
Qi Feng Yu ◽  
Ji Yong Chen ◽  
Xing Dong Zhang
Keyword(s):  
Heat Treatment ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Apatite Formation ◽  
Bioactive Materials ◽  
Hydroxyapatite Composite

The bioactivity of a composite of titania and hydroxyapatite was studied in vitro in this paper. After the titania ceramics was added 10% HA, it could induce apatite formation in simulated body fluid in 2d, while the pure titania ceramics could not induced apatite formation even after 14d. After the composite of titania and HA was subjected to alkali-heat treatment, it has a faster speed for apatite formation in SBF than the composite without treatment. When the osteoblast was cultured on the materials, the amount of osteoblasts attaching on the composite was more than that on the pure titania ceramics. It has the most osteoblasts cells on the composite subjected to alkali-heat treatment. These results showed that the composite of titania and HA is a bioactive materials, while the alkali-heat treatment could improved the bioactivity of this composite.

scholarly journals In Vitro Corrosion Studies of Surface Modified NiTi Alloy for Biomedical Applications

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Manju Chembath ◽  
J. N. Balaraju ◽  
M. Sujata
Keyword(s):  
Contact Angle ◽  
Photoelectron Spectroscopy ◽  
Electrochemical Impedance ◽  
Niti Alloy ◽  
Passive Layer ◽  
Water Contact ◽  
Force Microscopy ◽  
Corrosion Studies ◽  
Surface Modified

Electropolishing was conducted on NiTi alloy of composition 49.1 Ti-50.9 Ni at.% under potentiostatic regime at ambient temperature using perchloric acid based electrolyte for 30 sec followed by passivation treatment in an inorganic electrolyte. The corrosion resistance and biocompatibility of the electropolished and passivated alloys were evaluated and compared with mechanically polished alloy. Various characterization techniques like scanning electron microscopy, atomic force microscopy, and X-ray photoelectron spectroscopy were employed to analyze the properties of surface modified and mechanically polished alloys. Water contact angle measurements made on the passivated alloy after electropolishing showed a contact angle of 35.6°, which was about 58% lower compared to mechanically polished sample, implying more hydrophilicity. The electrochemical impedance studies showed that, for the passivated alloy, threefold increase in the barrier layer resistance was obtained when compared to electropolished alloy due to the formation of compact titanium oxide. The oxide layer thickness of the passivated samples was almost 18 times higher than electropolished samples. After 14 days immersion in Hanks’ solution, the amount of nickel released was 315 ppb which was nearly half of that obtained for mechanically polished NiTi alloy, confirming better stability of the passive layer.

Thermal and in vitro evaluation of a composite material pHEMA/Chitosan/Hydroxyapatite

2015 ◽  
Vol 1767 ◽  
pp. 133-138
Author(s):  
Areli.M. Salgado-Delgado ◽  
Zully Vargas-Galarza ◽  
René Salgado-Delgado ◽  
Efraín Rubio-Rosas ◽  
Edgar García-Hernández ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Body Fluid ◽  
Bone Tissue Regeneration ◽  
Gravimetric Analysis ◽  
Hydroxyethyl Methacrylate ◽  
Thermal Gravimetric ◽  
In Vitro Bioactivity ◽  
Bioactive Materials

ABSTRACTBioactive materials based on polymer/hydroxyapatite are currently being extensively investigated as materials for promotion of bone tissue regeneration and reconstruction [1]. In this work, a material interpenetrating based on poly 2-hydroxyethyl methacrylate (pHEMA), Chitosan and hydroxyapatite (HA) was prepared following the methodology of the foaming gas Damla Çetin [2], generating an interpenetrated network with the chitosan filled with hydroxyapatite. The materials were evaluated by thermal gravimetric analysis (TGA) and in vitro bioactivity [3] (SBF) and characterized by using scanning electron microscopy (SEM). The TGA studies suggested that there was not existence of possible interactions between polymers and HA but there is a thermal stability increase in the HA content. Meanwhile, SBF and its characterization by SEM, was found that the materials are bioactives as indicated by the formation of a bone-like apatite layer after immersion in simulated body fluid, indicating the potential of this material for use in bone tissue engineering.

Study on Surface Characterization and Properties of Three Dimensional Nano-Porous Titanium Film

2011 ◽  
Vol 492 ◽  
pp. 146-150 ◽  
Author(s):  
Yong Mei Ge ◽  
Cheng Yun Ning ◽  
Guo Xin Tan ◽  
Hua De Zheng ◽  
Dan Li
Keyword(s):  
Contact Angle ◽  
Body Fluid ◽  
Surface Characterization ◽  
Titanium Surface ◽  
Alkali Treatment ◽  
Three Dimensional ◽  
Porous Titanium ◽  
Titanium Film ◽  
Scanning Electron

A Type of Three-Dimensional Nano-Porous Film on Titanium Was Successfully Prepared by Alkali Treatment. the Microstructure, Contact Angle and Surface Energy of the Film Were Investigated Using Scanning Electron Microscopy (SEM) and Contact Angle Meter. the Biomineralization of the Nano-Porous Titanium Was Studied in Vitro by Soaking in Simulated Body Fluid (SBF). the Experiment Results Demonstrated that Bone-Like Apatite Could Be Induced on Nano-Porous Titanium Surface, and the Apatite Crystals on Nano-Porous Titanium Surface Were Superior in Number and Higher in Crystallinity to that on Titanium Chemically Polished.

Study of Phosphocalcic Glasses from SiO2-CaO-P2O5 System with and Without Silver II. The bioactivity analysis by FTIR, SEM methods and microbiological study of silver-doped glasses

2017 ◽  
Vol 68 (6) ◽  
pp. 1188-1192
Author(s):  
Daniela Avram ◽  
Nicolae Angelescu ◽  
Dan Nicolae Ungureanu ◽  
Ionica Ionita ◽  
Iulian Bancuta ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Body Fluid ◽  
Pathogenic Bacteria ◽  
De Novo ◽  
Microbiological Examination ◽  
Doped Glasses ◽  
P2o5 System ◽  
Scanning Electron

The study in vitro of the glass powders bioactivity was performed by soaking them in simulated body fluid for 3 to 21 days at a temperature of 37�C and pH = 7.20. The synthesis de novo of hydroxyapatite, post soaking was confirmed by Fourier Transform Infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The study of the antimicrobial activity was performed by microbiological examination on two strains of pathogenic bacteria involved in postoperative nosocomial infections.

IN-VITRO BEHAVIOUR OF BIPHASIC CALCIUM PHOSPHATE WITH DIFFERENT RATIO OF SILICA CONTENT IN SIMULATED BODY FLUID

2015 ◽  
Vol 23 (1) ◽  
pp. 1-14
Author(s):  
Sudirman Sahid ◽  
◽  
Nor Shahida Kader Bashah ◽  
Salina Sabudin ◽  
◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Biphasic Calcium Phosphate ◽  
Silica Content
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