Oligonucleotide Metallization for Conductive Bio-Inorganic Interfaces in Self Assembled Nanoelectronics and Nanosystems

2005 ◽  
Vol 872 ◽  
Author(s):  
Xu Wang ◽  
Krishna Singh ◽  
Chris Tsai ◽  
Roger Lake ◽  
Alexander Balandin ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Salt Solution ◽  
Peptide Nucleic Acid ◽  
Chemical Reduction ◽  
Pt Nanoparticles ◽  
The Self ◽  
Self Organization ◽  
Base Pairing ◽  
Pairing Mechanism ◽  
First Time

AbstractProperly designed sequences of oligonucleotides can be employed as scaffolds or templates for the self-organization of nanostructures and devices, through the Watson-Crick base pairing mechanism which serves as a programmable smart glue. In this paper, we report the Platinum metallization of peptide nucleic acid (PNA) sequences for the first time. PNA is an analogue of DNA and has a neutral backbone which provides stronger hybridization, greater stability and higher specificity in base pairing. Pt ions were reduced from a salt solution and localized over the PNA fragments where the size of the Pt colloids depends on the duration of chemical reduction. Computations of the high lying occupied and lowlying unoccupied orbitals indicated that Pt nanoparticles bind easily on both the Thymine (T) bases and the backbone in the PNA.

scholarly journals Evaluating the Effect of Ionic Strength on PNA:DNA Duplex Formation Kinetics

2021 ◽  
Author(s):  
Colin Swenson ◽  
Hershel H Lackey ◽  
Eric James Reece ◽  
Joel M. Harris ◽  
Jennifer Heemstra ◽  
...  
Keyword(s):  
Ionic Strength ◽  
Nucleic Acid ◽  
Peptide Nucleic Acid ◽  
Biological Applications ◽  
Base Pairing ◽  
Formation Kinetics ◽  
Acid Analog ◽  
Duplex Formation

Peptide nucleic acid (PNA) is a unique synthetic nucleic acid analog that has been adopted for use in many biological applications. These applications rely upon the robust Franklin-Watson-Crick base pairing...

Peptide nucleic acid mediated inhibition of the bacterial signal recognition particle

2018 ◽  
Vol 54 (59) ◽  
pp. 8257-8260 ◽  
Author(s):  
Sudipta Ghosh ◽  
Snehlata Saini ◽  
Ishu Saraogi
Keyword(s):  
Nucleic Acid ◽  
Peptide Nucleic Acid ◽  
Protein Transport ◽  
Signal Recognition Particle ◽  
Signal Recognition ◽  
Antibacterial Target ◽  
First Time

Here we propose and validate the signal recognition particle (SRP), a protein transport machinery, as an antibacterial target for the first time.

scholarly journals Self-assembly mechanism of Ni nanowires prepared with an external magnetic field

2015 ◽  
Vol 6 ◽  
pp. 2123-2128 ◽  
Author(s):  
Xiaoyu Li ◽  
Hu Wang ◽  
Kenan Xie ◽  
Qin Long ◽  
Xuefei Lai ◽  
...  
Keyword(s):  
Magnetic Field ◽  
External Magnetic Field ◽  
Self Assembly ◽  
Chemical Reduction ◽  
Reaction System ◽  
The Self ◽  
Nickel Nanowires ◽  
Assembly Mechanism ◽  
Nickel Particles ◽  
First Time

Nickel nanowires with a mean diameter of about 95 nm and lengths of up to 26 μm were prepared by a chemical reduction method in aqueous solution under an external magnetic field. The self-assembly mechanism was investigated in detail. The results indicate that the self-assembly process of Ni nanowires consists of three stages: nucleation and growth, ordered alignment and self-assembly, and deposition on the surface and gaps between the nickel particles. The self-assembly phenomenon occurs only when nickel particles grow to a size of about 60 nm in the reaction system. This critical size, which is proposed for the first time, is very important to comprehend the self-assembly mechanism of Ni nanowires prepared with an external magnetic field.

Constructing multifunctional MOF@rGO hydro-/aerogels by the self-assembly process for customized water remediation

2017 ◽  
Vol 5 (23) ◽  
pp. 11873-11881 ◽  
Author(s):  
Jiajun Mao ◽  
Mingzheng Ge ◽  
Jianying Huang ◽  
Yuekun Lai ◽  
Changjian Lin ◽  
...  
Keyword(s):  
Self Assembly ◽  
Synergistic Effects ◽  
Chemical Reduction ◽  
The Self ◽  
Water Remediation ◽  
Cross Linking ◽  
General Strategy ◽  
Assembly Process ◽  
One Step ◽  
First Time

We first time report a general strategy for one-step fabrication of a ZIF-8 MOF/RGO hydrogel, with the synergistic effects of chemical reduction and cross-linking by metal ions.

scholarly journals Peptide nucleic acid-ionic self-complementary peptide conjugates: highly efficient DNA condensers with specific condensing mechanism

RSC Advances ◽  
2017 ◽  
Vol 7 (7) ◽  
pp. 3796-3803 ◽  
Author(s):  
Meiwen Cao ◽  
Wenjing Zhao ◽  
Peng Zhou ◽  
Zilong Xie ◽  
Yawei Sun ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Peptide Nucleic Acid ◽  
Dna Condensation ◽  
Base Pairing ◽  
Pairing Interaction ◽  
Peptide Conjugates ◽  
Highly Efficient ◽  
Base Pairing Interaction

Peptide nucleic acid-ionic self-complementary peptide conjugates can induce efficient DNA condensation via base-pairing interaction and peptide association.

Molecular insights on the dynamic stability of peptide nucleic acid functionalized carbon and boron nitride nanotubes

2021 ◽  
Vol 23 (1) ◽  
pp. 219-228
Author(s):  
Nabanita Saikia ◽  
Mohamed Taha ◽  
Ravindra Pandey
Keyword(s):  
Nucleic Acid ◽  
Boron Nitride ◽  
Nucleic Acids ◽  
Dynamic Stability ◽  
Peptide Nucleic Acid ◽  
Rational Design ◽  
Peptide Nucleic Acids ◽  
Boron Nitride Nanotubes ◽  
Molecular Hybrids ◽  
Single Wall Nanotubes

The rational design of self-assembled nanobio-molecular hybrids of peptide nucleic acids with single-wall nanotubes rely on understanding how biomolecules recognize and mediate intermolecular interactions with the nanomaterial's surface.

Synergetic Theory of Document in Evolution of Document Science

2018 ◽  
pp. 1060-1068
Author(s):  
Galina A. Dvoenosova ◽  
Keyword(s):  
Social Role ◽  
Scientific Study ◽  
Self Organization ◽  
Universal Theory ◽  
Social Self ◽  
Social Goal ◽  
The Social ◽  
Synergetic Theory ◽  
First Time

The article assesses synergetic theory of document as a new development in document science. In information society the social role of document grows, as information involves all members of society in the process of documentation. The transformation of document under the influence of modern information technologies increases its interest to representatives of different sciences. Interdisciplinary nature of document as an object of research leads to an ambiguous interpretation of its nature and social role. The article expresses and contends the author's views on this issue. In her opinion, social role of document is incidental to its being a main social tool regulating the life of civilized society. Thus, the study aims to create a scientific theory of document, explaining its nature and social role as a tool of social (goal-oriented) action and social self-organization. Substantiation of this idea is based on application of synergetics (i.e., universal theory of self-organization) to scientific study of document. In the synergetic paradigm, social and historical development is seen as the change of phases of chaos and order, and document is considered a main tool that regulates social relations. Unlike other theories of document, synergetic theory studies document not as a carrier and means of information transfer, but as a unique social phenomenon and universal social tool. For the first time, the study of document steps out of traditional frameworks of office, archive, and library. The document is placed on the scales with society as a global social system with its functional subsystems of politics, economy, culture, and personality. For the first time, the methods of social sciences and modern sociological theories are applied to scientific study of document. This methodology provided a basis for theoretical vindication of nature and social role of document as a tool of social (goal-oriented) action and social self-organization. The study frames a synergetic theory of document with methodological foundations and basic concepts, synergetic model of document, laws of development and effectiveness of document in the social continuum. At the present stage of development of science, it can be considered the highest form of theoretical knowledge of document and its scientific explanatory theory.

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