Features of the clinical course of uterine fibroids of reproductive age women

2018 ◽  
pp. 102-106
Author(s):  
M.A. Flaksemberg ◽  
Keyword(s):  
Clinical Course ◽  
Inflammatory Diseases ◽  
Age Groups ◽  
Uterine Fibroids ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Subjective Data ◽  
Close Relatives ◽  
Methods Of Treatment ◽  
Adhesion Process

The objective: in this work represented part of materials of department rehabilitation of reproductive function for the examination and treatment of 250 patients with uterine fibrods in order to study and determine in detail the predictors of the disease, develop methods of treatment (conservative and surgical), as well as rehabilitation of the reproductive function, depending on the type and localization of the nodes. Materials and methods. The analysis of the anamnestic data, taking into account both objective and subjective data, analysis of anamnestic data of close relatives (maternal and paternal lines), concomitant genital and extragenital pathology is carried out. Results. The most numerical group of patients with uterine fibroids, according to our data, in the age groups of 26–35 years (32%) is 36–40 years (28.4%), which are the most socially and reproductively active. In this category, women with a high education of 33.6% and social status (30.4% and 22.4%) prevailed. The transferred inflammatory diseases of the genitals were noted in 48% of the examined, weighed gynecological anamnesis (abortions, miscarriages) were noted in 42.4%. Conclusion. Also for this category of patients is characterized by a high percentage of endometrial pathology – 60.8%, as well as concomitant adenomyosis – 34% and adhesion process of pelvic organs – 26.8%. Key words: clinical course, uterine fibroids, reproductive age.

scholarly journals Some features of the clinical course and treatment of cervical dysplasia depending on age

2021 ◽  
Vol 50 (1) ◽  
pp. 47-49
Author(s):  
V. V. Kropaneva ◽  
D. .F. Kostyuchek ◽  
S. Ya. Maximov
Keyword(s):  
Clinical Course ◽  
Cervical Dysplasia ◽  
Age Groups ◽  
Pathological Process ◽  
Biological Behavior ◽  
Methods Of Treatment

The article presents data on 231 cases of diagnosed cervical dysplasia in patients aged 21 to 80 years. The clinical course and biological behavior of the pathological process was studied depending on the severity and methods of treatment in patients in different age groups. A more aggressive course of the disease was noted in women under the age of 30.

scholarly journals Current trends in the pharmacotherapy of uterine myoma, associated with heavy menstrual bleeding and anemia: review

2020 ◽  
Author(s):  
Z. V. Revazova ◽  
L. V. Adamyan ◽  
O. N. Loginova ◽  
L. M. Manukyan ◽  
K. N. Arslanyan
Keyword(s):  
Uterine Fibroids ◽  
Reproductive Function ◽  
Uterine Myoma ◽  
Reproductive Age ◽  
Heavy Menstrual Bleeding ◽  
Menstrual Bleeding ◽  
Cochrane Library ◽  
Pharmacological Agents ◽  
Surgical Interventions ◽  
Current Trends

Aim: to summarize results of up-to-date world researches on the current trends of symptomatic myoma treatment.Materials and Мethods. A search of publications was carried out in the main international databases in Russian and English languages: PubMed/MEDLINE, The Cochrane Library, Embase, eLibrary. The analysis included studies published over the past 10 years examining the clinical efficacy and safety of various groups of pharmacological agents for the treatment of uterine myoma combined with heavy menstrual bleeding in women of reproductive age.Results. Currently, the treatment of uterine fibroids is divided into three main methods: surgical, minimally invasive organ-preserving methods, and pharmacotherapy. Until now, surgical intervention remains the main method of treatment, and, unfortunately, is often carried out in the volume of hysterectomy. However, today it is important to have a personalized approach to the management of a patient with symptomatic uterine myoma, taking into account her desire to preserve reproductive function. The development of the possibilities of drug therapy made a great contribution to the optimization of managing such patients.Conclusion. The global trend is to decrease the number of radical interventions, as well as the development and improvement of new methods of treating symptomatic uterine fibroids. Currently, pharmacotherapy of leiomyoma can significantly improve the quality of life of patients, reduce radical surgical interventions, optimize surgical treatment, and in certain situations, completely eliminate the need for surgery.

Rehabilitation of infertile patients after reconstructive plastic surgery on the pelvic organs

2021 ◽  
Vol 50 (3) ◽  
pp. 47-51
Author(s):  
E. M. Bakuridze ◽  
L. V. Dubnitskaya ◽  
T. A. Fedorova
Keyword(s):  
Postoperative Period ◽  
Reproductive Function ◽  
Early Postoperative Period ◽  
Reproductive Age ◽  
Comparative Group ◽  
Reconstructive Plastic Surgery ◽  
Methods Of Treatment ◽  
Reconstructive Plastic ◽  
Adaptive Reactions ◽  
Infertile Patients

The research aims at studying the effectiveness of plasmapheresis and ozonotherapy in treatment of women of reproductive age in early postoperative period after reconstructive-plastic operations. 110 patients with different factors of infertility who passed surgical laparoscopy were examined. All the patients were rehabilitated applying medicinal plasmapheresis (70 patients) and ozonotherapy (40 patients). The results of the study showed the advantages of these methods of treatment in comparison with traditional therapy (antibacterial and physiotherapy in comparative group, 72 patients). So, early rehabilitation of patients including medicinal plasmapheresis and ozonotherapy makes it possible to increase essentially the course of postoperative period, to stabilize adaptive reactions, to recover reproductive function in considerable amount of infertile women.

scholarly journals Optimization of diagnostic hyperplastic processes in the hormone-sensitiv organs (uterus, brest) during reproductive function reabilitation

2021 ◽  
Vol 6 ◽  
pp. 27-31
Author(s):  
O.D. Dubenko ◽  
M.A. Flaksemberh ◽  
A.Ye. Dubchak
Keyword(s):  
Menstrual Cycle ◽  
Uterine Leiomyoma ◽  
Inflammatory Diseases ◽  
Clinical Manifestations ◽  
Significant Risk ◽  
Reproductive Function ◽  
State Institution ◽  
Reproductive Age ◽  
Treatment And Prevention ◽  
Cycle Disorders

The objective: a study of the condition of the mammary glands in women with uterine leiomyoma on the background of inflammatory diseases of the genital organs. Materials and methods. At the first stage of the research, a retrospective analysis of histories of 246 women with infertility and uterine leiomyoma on the background of inflammatory diseases and pathology of mamma glands, who were treated in the department of family planning and rehabilitation of reproductive function of State Institution “Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine” named after Academician OM Lukyanova in 2015-2019 was done. In the second stage, a screening ultrasound examination to detect pathology of the breast was performed on the 6th-11th day of the menstrual cycle. Results. The severity of clinical manifestations of dyshormonal dysplasia of the breast depends on the influence of the most significant risk factors associated with mamma glands diseases: late reproductive age, number of interrupted pregnancies (abortion, miscarriage), genital diseases, age of menarche, the parameters of the menstrual cycle, disorders and duration of menstruations, duration of infertility and lactation, comorbid somatic pathology, especially liver disease, thyroid disease, frequent stress and severe heredity.Conclusions. The high frequency of combination of uterine leiomyoma and dyshormonal dysplasia of the breast in women with infertility indicates the need for timely diagnosis and adequate correction of this pathology as one of the factors in the development of mamma gland diseases and the earliest use of methods of rehabilitation of reproductive function. This will increase the effectiveness of infertility treatment and prevention of uterine and mammological pathology.

scholarly journals Specific Aspects of Life Quality Estimation and Ways of Rehabilitation in Women Who Underwent Uterine Surgery

2016 ◽  
Vol 23 (3) ◽  
Author(s):  
H. M. Havrylyuk ◽  
O. M. Makarchuk
Keyword(s):  
Blood Supply ◽  
Ovarian Function ◽  
Internal Iliac Artery ◽  
Life Quality ◽  
Uterine Fibroids ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Internal Iliac

Recently, it has been noticed a great number of uterine fibroids in women with unrealized reproductive function; moreover, the number of combined forms of hyperplastic processes of the reproductive system in 20-25% of women under 30 years of age and 60% of women over 40 years of age is constantly growing creating a favourable background for cancer. It is also known that women with hyperplastic processes suffer from psycho-emotional disorders both before surgeries and after surgical recovery; many of them are diagnosed with adjustment disorder. As many researches note, the main psychotherapeutic aspects include passive view of life, increased anxiety, tendency to dependent behaviour, rejection of own body, protective behaviour and problems with self-assessment. It should also be noted that a comprehensive study of clinical and laboratory data and subjective criteria of life quality is essential in assessment of the feasibility of hysterectomy in women of reproductive age, even if they do not plan to bear children in the future. The objective of the research was to estimate life quality as well as to improve the system of dispensary observation and rehabilitation of women who underwent uterine surgery.Materials and methods. There was performed a comprehensive examination and surgical treatment of 60 women of reproductive age with uterine fibroid who underwent hysterectomy with preservation of appendages. We used modern high quality endocrinological and instrumental techniques. The assessment of the received data was made immediately after surgery, 6 and 2 months, 3 and 5 years after surgery. Quality of life was studied on the basis of a comprehensive assessment using the modified scale of the Nottingham Health Profile and the study of such important indicators as energy, sleep, emotional reactions, social isolation, physical activity, pain. All statistical analysis was performed using a standard package “Statistica for Windows – 6.0”.Results and discussion. On the basis of anamnestic data of patients we revealed health deterioration with high rates of liver and gastrointestinal tract disorders, metabolic disturbances (obesity, hypertensive disorders, fibrocystic breast disease), metabolic-endocrine changes and surgery. Reproductive health in women with uterine fibroid was characterized by long establishment of regular menstrual cycle, its breach in the period of puberty, inflammatory diseases of the genital organs, benign ovarian tumours and their surgical removal, inadequate reproductive behaviour with absent or delayed implementation of reproductive function and induced abortion. 12 months and especially 5 years after surgery there was noticed a progressive deterioration of the ovarian function, which was reflected as the reduction in their volume due to the reduction in the number and size of follicles, deterioration of blood supply to the ovaries, decreased blood flow in the internal iliac artery basin. It should also be noted the progressive hypestrogenism; in addition, there was a clear correlation with the age of the woman, who underwent surgical operation. Changes in life quality of patients with hyperplastic processes of the uterus were manifested in the postoperative period as follows: a decrease in physical activity (43.33% of cases), increased sexual dysfunction (36.66%), inhibition of mental state, conflict-orientated social behaviour, weakening of role functions and subjective deterioration of health and life quality (51.66% of cases).Conclusions. Thus, surgery on uterine fibroids with total or subtotal hysterectomy contributes to interference in a complex neuroendocrine interaction between hypothalamus, pituitary, ovaries, adrenal cortex, thyroid gland and affects the blood supply, innervation, and lymph efflux in the pelvic floor; therefore, postoperative syndromes are polyglandular and polysystemic. Long-term effects after surgery are accompanied by progressive hypestrogenism, decrease in the ovarian function (the reduction in their volume observed during ultrasound examination), reduction in the number and size of follicles, deterioration of blood supply to the ovaries, low blood supply to the internal iliac artery basin.

scholarly journals The influence of clinical, pathological and surgical factors on the occurrence of recurrence of borderline ovarian tumors in different age groups

2019 ◽  
Vol 15 (2) ◽  
pp. 57-61
Author(s):  
F. V. Novikov ◽  
V. P. Bondarev ◽  
E. S. Mishina ◽  
M. V. Mnikhovich
Keyword(s):  
Age Groups ◽  
Reproductive Function ◽  
Ovarian Tumors ◽  
Reproductive Age ◽  
High Survival ◽  
Non Invasive ◽  
Borderline Ovarian Tumors ◽  
First Case ◽  
Biological Potential

Background. Borderline ovarian tumors (BOT), due to their unclear biological potential, remain a problem for oncogynecologists. On the one hand, frequent recurrences of tumors, and on the other hand, a high survival rate in the diagnosis of patients requires careful weighing of all risk factors when choosing surgical intervention tactics in patients with BOT. A large number of recurrences of BOT in patients of fertile age lead to disability of patients, deterioration of their quality of life and loss of reproductive function.Objective: evaluation of the influence of clinical and morphological factors (the presence of non-invasive implants, bilateral lesion of the ovaries, the presence of psammous bodies and malignization tricks) and surgical factors (damage to the cyst capsule and carrying out fertility preserving operations) on the recurrence of BOT in various age groups.Materials and methods. The material for the study was the protocols of an in vivo pathoanatomical study of a biopsy (surgical) material obtained from patients with a diagnosis of BOT for the period from 2000 to 2017 inclusive, according to the Regional Forensic Medical Bureau of Kursk. A total of 110 protocols for the first occurrence of BOT and 14 protocols for the tumor recurrences were analyzed. The age of patients undergoing an in vivo pathologic examination ranged from 19 to 75 years.Results and conclusions. It has been revealed that psammous bodies, fertility preserving operations and reproductive age are associated with tumor recurrence. Groups of patients with foci of malignancy and bilateral lesions have a lower risk of BOT recurrence due to the radical surgical treatment tactics and possibly the use of chemotherapy in the first case. Non-invasive implants are not associated with the risk of BOT recurrence.

scholarly journals CONSERVATIVE COMBINATION TREATMENT OF CERVICAL ECTOPIC PREGNANCY FOR 7 WEEKS OF PREGNANCY WITH THE USE OF SELECTIVE ANGIOGRAPHIC UTERINE ARTERY EMBOLIZATION, FOLLOWEDBY HYSTEROSCOPIC RESECTION OF THE OVUM

2016 ◽  
Vol 7 (4) ◽  
pp. 34-40
Author(s):  
S I Askolskaya ◽  
S I Alikberova ◽  
Yuriy Vyacheslavovich Popov ◽  
D P Lebedev ◽  
O E Nechaeva
Keyword(s):  
Conservative Therapy ◽  
Reproductive Function ◽  
Reproductive Age ◽  
High Tech ◽  
Women Of Reproductive Age ◽  
Artery Embolization ◽  
Excessive Bleeding ◽  
Methods Of Treatment ◽  
Minimally Invasive Methods ◽  
Hysteroscopic Resection

Cervical pregnancy is a currently important medical and social problem, characterized by relatively high mortality and often leads to a loss of fertility in women of reproductive age. This clinical case demonstrates a possible approach of conservative therapy in conditions of excessive bleeding in women interested in the reservation of reproductive function, using high-tech minimally invasive methods of treatment in combination with chemotherapy.

scholarly journals Problem Tuboperitoneal Infertility in Women of Reproductive Age

2019 ◽  
Vol 5 (5) ◽  
pp. 46-50
Author(s):  
S. Abramova ◽  
L. Zaidulina ◽  
D. Grachev ◽  
D. Iseev ◽  
I. Syatkina
Keyword(s):  
Russian Federation ◽  
Inflammatory Diseases ◽  
Family Health ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Fallopian Tubes ◽  
Women Of Reproductive Age ◽  
Clinical Factor ◽  
The Russian Federation ◽  
Effectiveness And Efficiency

Family health is an indicator reflecting the health status of the population. According to world statistics around the world about 15% of couples suffer from infertility. The proportion of infertile couples in the Russian Federation varies from 8 to 21%, while more than 55% of cases of infertility are due to impaired reproductive function. Inflammation of the fallopian tubes is one of the main causes of infertility. According to many authors in the Russian Federation, in groups of women up to 38 years old, inflammatory diseases of the pelvic organs occur from 20% to 50%. As a result of the development of damage to the fallopian tubes, the risk of developing tuboperitoneal infertility is high. According to statistics, every fifth woman has chronic inflammations, while 75% of them have adhesions in the small pelvis, in which the fallopian tubes are affected, not even having surgical treatment. All the above facts make the problems of tuboperitoneal infertility extremely low. This article presents the results of a clinical–factor analysis of tuboperitoneal infertility in women of reproductive age. Considered in detail the main factors that ensure the effectiveness and efficiency of the treatment in accordance with the algorithms of therapeutic and diagnostic tactics.

scholarly journals Study of causal factors of uterine fibroids development in patients of reproductive age

2019 ◽  
Vol 2 (14) ◽  
pp. 52-54
Author(s):  
S. M. Safarova ◽  
G. U. Bolieva ◽  
N. J. Abdurahmanova
Keyword(s):  
High Frequency ◽  
Inflammatory Diseases ◽  
Varicose Veins ◽  
Uterine Fibroids ◽  
Mammary Glands ◽  
Uterine Myoma ◽  
Reproductive Age ◽  
Deficiency Anemia ◽  
Menstrual Dysfunction ◽  
Status Of Women

The somatic and gynecological status of women with uterine myoma is presented. A significantly high frequency of concomitant extragenital pathology was revealed, including: iron deficiency anemia, thyroid and urinary tract diseases, pathology of the gastrointestinal tract, obesity and varicose veins. It has been established that patients with uterine myoma often suffer from menstrual dysfunction of the type of hypermenstrual syndrome and algodimenorrhea, menometrorrhagia. More than half of the examined women with uterine myoma detected a combination of this pathology with endometrial hyperplasia, benign ovarian formations, pelvic inflammatory diseases, cystic fibrosis of the mammary glands.

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