Polyurethane dressing, tetracycline and salicylic acid use for treatment of digital dermatitis in cattle

2015 ◽  
Vol 43 (06) ◽  
pp. 350-358 ◽  
Author(s):  
C. Sauter-Louis ◽  
J. Maierl ◽  
A. Fiedler
Keyword(s):  
Salicylic Acid ◽  
Topical Treatment ◽  
Wound Dressing ◽  
Latency Period ◽  
Test Group ◽  
Therapeutic Effects ◽  
Digital Dermatitis ◽  
Absolute Minimum ◽  
Clinical Appearance ◽  
Conventional Methods

SummaryObjective: The use of antibiotics is a proven approach for local and systemic treatment of digital dermatitis (DD). Even if they are administered only locally and at low dosage, their use should be restricted to an absolute minimum. The efficacy of a commercial polyurethane wound dressing in treating acute digital dermatitis was compared with topical treatment using a commercially available tetracycline spray and a salicylic acid paste. Materials and methods: A total of 105 cows in a dairy farm (with about 160 dairy cows) were included in the study, with 101 cows needing topical treatment for digital dermatitis on one or both hind feet. All animals underwent hoof trimming prior to the treatment. Affected feet (n = 152) were randomly assigned to one of three comparable treatment groups. Topical treatment was administered to all visible digital dermatitis lesions. Animals in the positive control groups were given a topical treatment of tetracycline (53 DD lesions in 49 cows) or salicylic acid (53 DD lesions in 50 cows) formulations, whose therapeutic effects were scientifically verified. Spray was applied once, at a usual dosage and without any bandage. Salicylic acid paste was fixed in place with a bandage for 5 days. In the test group (46 DD lesions in 45 cows), a polyurethane bandage was left in place for 10 days. Whereas, 47 feet (from 38 cows) without lesions or with lesions showing no pain were designated as group 0. Each lesion was evaluated at day 0 during trimming, and on day 10 and 36. The lesions were scored based on severity and size. Results: All groups showed a statistically significant improvement in the clinical appearance of the lesions at day 10. There were no significant differences in the findings between the second and the third evaluation (day 10 and day 36) either within a group or between the groups. Conclusion: The use of an alternative treatment regimen like a polyurethane wound dressing shows good clinical healing, it is as effective as the conventional methods, and unlike the conventional methods, does not require a latency period.

scholarly journals Bovine digital dermatitis in the Brazilian Amazon biome and topical treatment with Copaifera reticulata oil

2020 ◽  
Vol 40 (11) ◽  
pp. 842-851
Author(s):  
Henrique A. Bomjardim ◽  
Mariana C. Oliveira ◽  
Marilene F. Brito ◽  
Carlos M.C. Oliveira ◽  
Bruno M. Monteiro ◽  
...  
Keyword(s):  
Salicylic Acid ◽  
Dairy Cows ◽  
Topical Treatment ◽  
Brazilian Amazon ◽  
The State ◽  
Control Measures ◽  
Digital Dermatitis ◽  
Copaiba Oil ◽  
Microscopic Features ◽  
Low Prevalence

ABSTRACT: Bovine Digital Dermatitis (BDD) was studied in crossbred dairy cows grazing in Rondon do Pará, in the state of Pará, as well as in Açailândia and Cidelândia, in the state of Maranhão, Brazilian Amazon biome. The digits inspection from the dairy cows during milking was performed in ten farms comprising four visits (August and November 2016; April and July 2017). The cows were kept all year in pastures, and were mechanically milked on concrete floors and the animals were protected against the rains in eight farms, maintaining a daily cleaning, however, it could not be found a concrete floor in pre- or post-milking to ensure milking parlor on three farms. Manual milking on no concrete floors was performed in two farms. No preventive measures against hoof lesions were adopted. The BDD prevalence was 1.3% (22/1664), and no statistical difference among rainy or no rainy season was obtained (p = 0.72). The BDD lesions were classified according to “M system” (M0 = no lesion, M1 = active ulceration <2cm, M2 = active ulceration >2cm, M3 = healing stage, M4 = chronic stage, M4.1 = M4 with active ulceration). Regarding the 22 BDD lesions observed, 22.7% (5/22) were M1 stage, 36.4% (8/22) M2, 22.7% (5/22) M3, 13.6% (3/22) M4 and 4.5 (1/22) M4.1. Hypertrophic hairs at the edges of the lesions caused by fly larvae of genus Cochliomyia spp. as well as alterations on the hoof were also observed. Topical treatment was performed in six BDD lesions with a raw extract from trees of the genus Copaifera reticulata (Copaiba oil) and compared with the treatment of salicylic acid paste in five BDD lesions. The lesions were protected with a bandage for seven days and followed weekly until recovery. The complete therapeutic responses were 83.4% (5/6) and 75% (3/4), respectively, with an average time of seven weeks. The BDD in the Amazon biome occurs in low prevalence, not seasonal, and presents macro and microscopic features similar to BDD lesions from dairy cattle kept in free-stall housing. The treatment with copaiba oil showed similar results to the treatment of salicylic acid paste and can be used in control measures to BDD in the Amazon biome.

scholarly journals Optimization of The Electrospinning Process for Preparation of Nanofibers From Poly (Vinyl Alcohol) (PVA) and Chromolaena odorata L. Extrac (COE)

2020 ◽  
Vol 16 (1) ◽  
pp. 47-56
Author(s):  
I. Sriyanti ◽  
L. Marlina ◽  
J. Jauhari
Keyword(s):  
Wound Dressing ◽  
Fiber Diameter ◽  
Sem Analysis ◽  
Electrospinning Process ◽  
The Body ◽  
Poly Vinyl Alcohol ◽  
Therapeutic Effects ◽  
Important Process ◽  
Chromolaena Odorata ◽  
Solubility In Water

The Cromaloena odorata (COE) contains phenols, flavonoids, tannins, alkaloids, saponins, steroids that possess diverse therapeutic effects. However, COE has poor solubility in water and poor absorbtion in the body. Incorporation of COE in nanofiber system is a promising way to increase CEO solubility. One of the method to produce nanofiber is electrospinning. The electrospinning process there are three of the most important process parameters are applied flowrate, voltage and TCD. In this study we developed optimized condition for electrospinning process of polyvinyl alcohol (PVA)/CEO and their characterization. The Scanning electron microscopy (SEM) analysis showed that modification of flowrate and TCD did not affect the morphology of PVA and COE fiber. However fiber diameter decreased when lower flowrate, higher voltage was applied, and TCD. Fourier Transform Infrared (FTIR) study was conducted to identify possible intermolecular interaction between PVA/COE that has potential application as antimicrobial wound dressing.

scholarly journals Shortening of bones using novel contraction osteogenesis device: An experimental study

2021 ◽  
Vol 11 (Suppl. 1) ◽  
pp. 26-31
Author(s):  
Hakan Ocak ◽  
Erdem Kılıç ◽  
Alper Alkan
Keyword(s):  
Experimental Study ◽  
Maxillofacial Surgery ◽  
Latency Period ◽  
Test Group ◽  
Study Groups ◽  
Skin Incision ◽  
Alternative Methods ◽  
Control Group ◽  
Oral And Maxillofacial Surgery ◽  
Complication Rates

Aim: Given the high complication rates associated with orthognathic surgery for the correction of maxillomandibular malformations, studies have focused on alternative methods of strengthening the jaw, such as distraction osteogenesis. However, methods of shortening of the jaw are not well-elucidated in oral and maxillofacial surgery practice. This study aims to investigate the efficacy of a new method of shortening osteotomized jaws. Methodology: A 2.5–3 cm skin incision was made on the left tibia of each of 15 New Zealand white rabbits aged 12–18 months, followed by fixation of 15 mm pre-opened distractor devices to the tibia after osteotomy. After a five-day latency period, the distractors were activated to a total of 8 mm, with closure of the device set at a rate of 0.25 mm/day in the test group. After a five-day latency period, the distractors closed at a rate of 0.125 mm/day, achieving a total contraction of 5 mm. The distractors were not activated in the control group. The bone at the contraction range was evaluated, and the resultant shortening was measured. Results: The tibia was shortened by an average of 4.32 mm. Exaggerated bone formation was identified around the osteotomized cortical bone in all rabbits in the control and study groups, and there were minimal complication rates. Conclusion: This study verified that the jaw can be shortened by performing slow, controlled contraction with a bone resorption pattern.   How to cite this article: Ocak H, Kılıç E. Alkan A, Shortening of the bones using a novel contraction osteogenesis device: An experimental study. Int Dent Res 2021;11(Suppl.1):26-31. https://doi.org/10.5577/intdentres.2021.vol11.suppl1.5   Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

Comparing the curative efficacy of topical treatment with thiamphenicol and oxytetracycline on digital dermatitis lesions in dairy cattle

2017 ◽  
Vol 180 (20) ◽  
pp. 500-500 ◽  
Author(s):  
M. Holzhauer ◽  
R. Ploegmakers-van Deventer ◽  
D. Smits ◽  
W. Swart
Keyword(s):  
Dairy Cattle ◽  
Topical Treatment ◽  
Digital Dermatitis

Graphene oxide incorporated collagen–fibrin biofilm as a wound dressing material

RSC Advances ◽  
2014 ◽  
Vol 4 (107) ◽  
pp. 62717-62727 ◽  
Author(s):  
R. Deepachitra ◽  
V. Ramnath ◽  
T. P. Sastry
Keyword(s):  
Graphene Oxide ◽  
Composite Film ◽  
Wound Dressing ◽  
Conventional Methods

GO was incorporated in the collagen and fibrin composite film (CFGO), these films were used as wound dressing material on the experimental wounds of rats and the efficacy of CFGO was studied using conventional methods (schematic illustration).

scholarly journals Efficacy of Argentine propolis formulation for topical treatment of canine otitis externa

2010 ◽  
Vol 62 (6) ◽  
pp. 1359-1366 ◽  
Author(s):  
L.A Lozina ◽  
M.E Peichoto ◽  
S.I Boehringer ◽  
P Koscinczuk ◽  
G.E Granero ◽  
...  
Keyword(s):  
Topical Treatment ◽  
Otitis Externa ◽  
Culture Media ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Coagulase Negative Staphylococcus ◽  
Therapeutic Effects ◽  
Microbiological Analysis ◽  
Topical Formulation ◽  
Malassezia Pachydermatis

The therapeutic effects of Argentine propolis ear drop formulation on canine otitis externa were evaluated. Forty-eight dogs with symptoms of otitis externa were randomly assigned to double-blinded, controlled clinical trial to evaluate the efficacy of topical formulation with propolis versus a topical placebo in the treatment of otitis externa. The propolis preparation and placebo were administrated into both external ear canals, twice daily for 14 days. Throughout the study, clinical examination and microbiological analysis of dogs ear exudates were made. The most frequent microorganisms isolated in culture media were: Malassezia pachydermatis (54.2%), Staphylococcus aureus (43.8%), coagulase-negative Staphylococcus (25.0%), Pseudomonas aeruginosa (20.8%), Candida albicans (18.8%), Proteus mirabilis (16.7%), Streptococcus spp. (16.7%), Enteroccocus faecalis (12.5%), Escherichia coli (12.5%), Staphylococcus intermedius (6.3%), Klebsiella spp. (4.2%), andCandida glabrata (2.1%). Whereas the control group did not recover from the infectious ear disease, the propolis preparation exhibited antimicrobial activity against most of the microorganisms isolated from samples of the treated group. In addition, no propolis-adverse effects were observed. This allowed propolis-treated patients to show a significant improvement of the clinical parameters. Thus, this new Argentine propolis ear drop formulation may be used for topical treatment of otitis externa in dogs.

Improvement of dairy cow embryo yield with low level laser irradiation

2017 ◽  
Vol 20 (2) ◽  
pp. 307-312 ◽  
Author(s):  
G. Palubinskas ◽  
V. Žilaitis ◽  
R. Antanaitis
Keyword(s):  
Laser Irradiation ◽  
Dairy Cow ◽  
Test Group ◽  
Control Group ◽  
Low Level ◽  
Low Level Laser ◽  
Embryo Yield ◽  
Level Laser ◽  
Conventional Methods ◽  
Low Level Laser Irradiation

Abstract The goal of this study is to estimate the effects of low-level laser irradiation (LLLI) on the superovulatory response according to the number of corpora lutea (CL), follicles (F) and the embryo yield. In recent years, while searching for new, more efficient and organic methods to improve superovulatory response and embryo yield with respect to the conventional methods, low-level laser irradiation (LLLI) is a more sensitive and less costly technology that can be used to improve animal reproduction, namely, artificial insemination and the embryo production system. The dairy-cow donors were treated for superovulation with Pluset®, at any time during the oestrus cycle, and the total dose per donor was 700 IU. The first group of the donors (n=25), test group (TG), was irradiated on the sacroiliac area for 180 seconds per day, from the 1st to 11th superovulatory treatment (ST) days in a row, with LLLI in the 870-970-nm wavelength, 65.93 J/cm dose, frequencies in the 20-2000 Hz range and pulse durations commonly in the range of about 1 second. For the second control group (CG) (n=25), the ST was performed without LLLI. After the ST, The mean number of CL in the right side ovaries in the TG was 25.43% (p<0.05) greater than in those of the CG. The number of total recovered and transferable embryos was greater in the TG compared with the CG by 28.97% (p<0.05) and 15.8% (p>0.05), respectively. With respect to conventional methods, LLLI can be used to improve the superovulatory response and embryo yield as a supplementary environment and animal-friendly method of treatment.

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