scholarly journals Effects of square stepping exercise in patients with sequel of cerebrovascular accident

2014 ◽  
Vol 27 (2) ◽  
pp. 229-237
Author(s):  
Grazieli Silva Túbero ◽  
Sebastião Gobbi ◽  
Camila Vieira Ligo Teixeira ◽  
Jessica Rodrigues Pereira ◽  
Ryosuke Shigematsu ◽  
...  
Keyword(s):  
Cognitive Functions ◽  
Verbal Fluency ◽  
Depression Scale ◽  
Cognitive Status ◽  
The Body ◽  
Wilcoxon Test ◽  
Cerebral Stroke ◽  
Timed Up And Go ◽  
Body Balance ◽  
Stepping Exercise

Introduction Cerebral stroke is the interruption of blood flow to the brain and can be classified into hemorrhagic and ischemic. It may result in serious body balance and cognition complications. Kinesiotherapy is a privileged means of rehabilitation.Objective Verify the effects of Square Stepping Exercise (SSE) on cognitive functions, depressive symptoms and the body balance of cerebral stroke sequel patients.Methods Thirteen brain stroke sequel patients were divided into two groups: SSE (SSEG n = 8) and conventional physiotherapy group (PG, n = 5). The SSEG participated only of the SSE training protocol, while the PG participated of its physical therapy routine group, both for 4 months. They were evaluated using the Mini Mental State Examination (MMSE), the Brief Cognitive Screening Battery (BBRC), the Geriatric Depression Scale (GDS),Berg Balance Scale(BBS) and Timed Up and Go(TUG).Results The U Mann Whitney test showed no significant differences between groups. In intragroup analysis, the Wilcoxon test showed significant improvement in global cognitive status for PG (p < 0.042), and for SSEG there were positive results for verbal fluency (p < 0.04) and in TUG for number of steps (p < 0.04) and the time (p < 0.02).Conclusion The SSE seems to benefit dynamic balance, influencing gait agility, cognition related to verbal fluency and may have contributed to maintain other cognitive functions.

scholarly journals Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2362 ◽  
Author(s):  
Hidese ◽  
Ogawa ◽  
Ota ◽  
Ishida ◽  
Yasukawa ◽  
...  
Keyword(s):  
Cognitive Functions ◽  
Verbal Fluency ◽  
Controlled Trial ◽  
Depression Scale ◽  
Healthy Adults ◽  
Placebo Administration ◽  
Double Blind ◽  
Randomized Controlled ◽  
Median Split ◽  
The Mean

This randomized, placebo-controlled, crossover, and double-blind trial aimed to examine the possible effects of four weeks L-theanine administration on stress-related symptoms and cognitive functions in healthy adults. Participants were 30 individuals (nine men and 21 women; age: 48.3 ± 11.9 years) who had no major psychiatric illness. L-theanine (200 mg/day) or placebo tablets were randomly and blindly assigned for four-week administration. For stress-related symptoms, Self-rating Depression Scale, State-Trait Anxiety Inventory-trait, and Pittsburgh Sleep Quality Index (PSQI) scores decreased after L-theanine administration (p = 0.019, 0.006, and 0.013, respectively). The PSQI subscale scores for sleep latency, sleep disturbance, and use of sleep medication reduced after L-theanine administration, compared to the placebo administration (all p < 0.05). For cognitive functions, verbal fluency and executive function scores improved after L-theanine administration (p = 0.001 and 0.031, respectively). Stratified analyses revealed that scores for verbal fluency (p = 0.002), especially letter fluency (p = 0.002), increased after L-theanine administration, compared to the placebo administration, in individuals who were sub-grouped into the lower half by the median split based on the mean pretreatment scores. Our findings suggest that L-theanine has the potential to promote mental health in the general population with stress-related ailments and cognitive impairments.

scholarly journals The factors influencing the functional state recovery in cerebral stroke patients during the second rehabilitation stage

Medicina ◽  
2008 ◽  
Vol 44 (7) ◽  
pp. 500 ◽  
Author(s):  
Eglė Milinavičienė ◽  
Daiva Rastenytė ◽  
Aleksandras Kriščiūnas
Keyword(s):  
Functional State ◽  
Significant Influence ◽  
Cognitive Functions ◽  
Prognostic Value ◽  
The Body ◽  
Cerebral Stroke ◽  
Stroke Patients ◽  
Second Stage ◽  
Factors Influencing ◽  
The Mean

The aim of the study was to determine the functions influencing the recovery of the motor and cognitive functions and general functional state in cerebral stroke patients during the second rehabilitation stage, and their prognostic value. The contingent and methods. The studied contingent consisted of 226 cerebral stroke patients: 109 men and 117 women who had undergone the second stage rehabilitation in Viršužiglis Rehabilitation Hospital, a branch institution of Hospital of Kaunas University of Medicine. The mean age of the patients was 67.8±10.4 years. The greatest proportion of the patients (88.5%) was with cerebral infarction. The mean duration of rehabilitation was 38.8±8.9 days. The functional state of the patients was assessed by functional IndependenceMeasure; the cognitive function, by the short mental function study method; the severity of the stroke, in accordance with the National Institutes of Health Stroke Scale. The prognostic value of the factors was evaluated by the logistic regression method. A study analyzed the influence of patient’s gender, age, social factors, clinical symptoms and signs, risk factors for stroke, comorbities, the character and localization of the stroke, and psychoemotional state on the recovery of capacities related to motor and cognitive functions, and restoration of general functional state. Results. During the second stage of rehabilitation, the score of the functional state of the patients assessed by the Functional Independence Measures significantly improved from 65.9±20.3 to 93.5±20.9 (P<0.0001). At the end of rehabilitation, good efficacy of rehabilitation was determined in 64.2% of the rehabilitees; moderate, in 19.4%; insufficient, in 16.4%. In prognosing insufficient recovery of general functional state during the second stage of rehabilitation, the following factors had a significant influence: extremity hemiplegia, disturbed cognitive functions, urination impairment, joint and heart diseases. In cases of insufficient recovery of capacities linked with motor function in the second stage of rehabilitation, exerted extremity hemiplegia, neglect of the affected side of the body, urination impairments, joint and heart disorders had a significant influence, whereas localization of the stroke lesion in the left hemisphere of the brain, impairment of cognitive functions (disturbance of speech and perception), urination disturbances – on the insufficient recovery of capacities related to cognitive functions. Conclusion. Insufficient efficacy of rehabilitation of the rehabilitees with cerebral stroke in the second stage of rehabilitation was influenced by impairment of motor and cognitive functions, urination disturbancies, and comorbidities. In forming individualized inpatient rehabilitation programs and prognosing the further health care of patients with cerebral stroke, it is important to pay attention to factors, influencing insufficient efficacy of rehabilitation.

scholarly journals Relationship between antipsychotic medication, obesity and cognitive functions

2017 ◽  
Vol 18 (4) ◽  
pp. 272-278
Author(s):  
Urszula Łopuszańska ◽  
Marta Makara-Studzińska
Keyword(s):  
Cognitive Function ◽  
Waist Circumference ◽  
Abdominal Obesity ◽  
Cognitive Functions ◽  
Verbal Fluency ◽  
Verbal Learning ◽  
The Body ◽  
Typical Antipsychotic ◽  
Antipsychotic Medications ◽  
Learning Test

AbstractIntroduction: The purpose of this study was to examine whether the combination of atypical and typical antipsychotic medications is related with metabolism and cognitive functions in the same manner and degree as taking medications of one kind only, i.e. atypical or typical.Material and methods: The participants of the study comprised of 91 adults with diagnosed mental illness (F-20-F69). The participants were divided into groups on the basis of the kind of administered medications: T+A (typical and atypical medications), A (atypical medications), T (typical medications), P (antidepressants, sedatives, normothymic/antiepileptic drugs). In the study, Short Test of Mental Status (STMS), Verbal Fluency Test (VFT), Rey Auditory Verbal Learning Test (RAVLT) were used for the purpose of examining cognitive functions.Results: The kind of antipsychotic medications taken by the patients did not differentiate the group in relation to BMI (p<0.13), nor in relation to the level of general cognitive function (p<0.72) or verbal fluency (p<0.34). Both atypical antipsychotic medications and the combination of atypical and typical medications were related to the occurrence of abdominal obesity (p<0.01). An increase in waist circumference decreased an ability of abstract reasoning (p<0.005). When it comes to the body mass index, waist circumference negatively correlated with the delayed memory (p< 0.03, p<0.004).Discussion: Both the combination of atypical and typical antipsychotic medications and atypical medications are associated with the occurrence of abdominal obesity. The deposition of fat tissue in the abdomen negatively correlated with an ability to learn.Conclusions: The future studies might explain the interactions between antipsychotic medications, obesity and cognitive function.

scholarly journals Experience with citicoline in patients with post-stroke cognitive impairment

2020 ◽  
Vol 12 (4) ◽  
pp. 43-48
Author(s):  
A. N. Bogolepova ◽  
S. G. Burd ◽  
A. V. Lebedeva ◽  
E. A. Kovalenko
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Functions ◽  
Time Course ◽  
Depressive Disorders ◽  
Recovery Period ◽  
Depression Scale ◽  
Oral Solution ◽  
Cognitive Status ◽  
Post Stroke ◽  
Number Of Patients

Objective: to investigate the efficacy and safety of citicoline (Ceresil® Canon) in patients with post-stroke cognitive impairment.Patients and methods. Examinations were made in 33 patients aged 45 years and older who had experienced primary ischemic hemispheric stroke with complaints of a decline in memory or other cognitive functions. The cognitive status was assessed using the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA). The presence of anxiety-depressive spectrum disorders was determined on the Hospital Anxiety and Depression Scale. All the patients received citicoline (Ceresil® Canon) oral solution at a dose of 1000 mg/day for 3 months.Results and discussion. Citicoline administration showed a statistically significant reduction in the severity of cognitive impairment (p<0.001). The time course of positive changes in the cognitive status of patients was reflected by an increase in the median score on the MMSE from 26 [25; 27.5] to 28 [26.5; 29] and on MoCA from 23 [21; 25] to 25 [22; 26]. There was a decline in the number of patients with anxiety-depressive disorders. No adverse events or side effects were found in the patients.Conclusion. The findings suggest that citicoline (Ceresil® Canon) produced as an oral solution is well tolerated and improves cognitive functions and affective sphere in patients in the recovery period of ischemic stroke.

scholarly journals Pengaruh Senam Vertigo (Canalit Reposition Treatment) Terhadap Keseimbangan Tubuh Pada Pasien Vertigo

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Eni Sumarliyah ◽  
Suyatno Hadi Saputro
Keyword(s):  
Treatment Group ◽  
Design Research ◽  
Sampling Technique ◽  
Simple Random Sampling ◽  
Pharmacological Therapy ◽  
The Body ◽  
Wilcoxon Test ◽  
Control Group ◽  
Body Balance ◽  
And Control

This study aims to analyze the effect of vertigo (canalit reposition treatment) exercise on body balance in vertigo patients and treatments. The specific purpose of this research is to identify the balance of the body in the control group and the design in this study is a Quasy Experimental study using a Static Group Comparison / Non Exuivalent Group Design research design approach. The hallmark of this research is revealing a causal relationship by looking at one treatment group compared to the control group. The treatment group was observed body balance before vertigo gymnastic intervention (canalit reposition treatment), then observed again after vertigo gymnastic intervention (canalit reposition treatment), while the control group only observed body balance without giving treatment. The population in this study were patients who were hospitalized with simple random sampling technique. Data collection was carried out through questionnaires and observations, then the data was processed and analyzed using the Wilcox statistical test with α 0.05.Based on the results of research that has been done obtained from the Wilcoxon test in the treatment group obtained α = 0,000. While from the control group, the result α = 0.003 This means that there is an influence between Vertigo Gymnastics (Canalit Reposition Treatment) on Body Balance in Vertigo Patients. However, there were differences between the treatment and control groups. Based on these results, the Vertigo Gymnastics (Canalit Reposition Treatment) affects the body’s balance in Vertigo patients.We are confident that Vertigo Gymnastics (Canalite Reposition Treatment) can be used in Vertigo patients in dealing with disorders of body balance as a companion therapy in addition to pharmacological therapy. With Vertigo Gymnastics (Canalite Reposition Treatment), balance disorders can be resolved immediately and the problem of comfort disorders in patients will be resolved as soon as possible.

scholarly journals Sex characteristics of cognitive functions assessed by the MMSE and MoCA scores in patients with coronary artery disease

2021 ◽  
Vol 26 (2) ◽  
pp. 4194
Author(s):  
I. V. Tarasova ◽  
O. A. Trubnikova ◽  
A. S. Sosnina ◽  
I. D. Syrova ◽  
I. N. Kukhareva ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Coronary Artery ◽  
Cognitive Functions ◽  
Verbal Fluency ◽  
Clinical Laboratory ◽  
Mmse Score ◽  
Artery Bypass ◽  
Cognitive Status ◽  
Sex Characteristics ◽  
Severe Cognitive Impairment

Aim. To study the sex characteristics of cognitive functions in a cohort of patients undergoing coronary artery bypass grafting (CABG) by comparing the results of Mini-mental state examination (MMSE) and Montreal Cognitive Assessment (MoCA) scores.Material and methods. The prospective cohort study included 272 people, including 74 women aged 41 to 82 years, who were admitted to the Research Institute of Complex Issues of Cardiovascular Diseases for CABG surgery. All patients underwent clinical, laboratory, electrophysiological and ultrasound examinations. The Charlson comorbidity index (CCI) was calculated. Assessment of cognitive functions was carried out using the MMSE and MoCA scores. All types of statistical analysis were performed using the STATISTICA 10 program (StatSoft Inc., USA).Results. It was found that women scheduled for CABG have an older age and a higher CCI score compared to men (p=0,008). According to the MMSE, the likelihood of moderate and severe cognitive impairment in men compared with women was 1,36 times higher (odds ratio (OR), 1,35; 95% confidence interval (CI), 0,79-2,32, Z=1,11, p=0,27). The MoCA scores showed that half of the male (49%) and female (50%) participants had severe cognitive impairment. The likelihood of moderateand severe cognitive impairment in men compared with women was 1,33 times higher (OR, 1,33; 95% CI, 0,68-2,59, Z=0,841, p=0,40). According to subtests of the MoCA, men were better in naming (p=0,002), abstraction (p=0,005), and women outperformed men in verbal fluency (p=0,04). Regression analysis revealed that the most significant negative predictors for cognitive status as measured by the MMSE and MoCA scores for men and women were age and CCI.Conclusion. Women scheduled for CABG, having the worst clinical and demographic indicators, are comparable with men in cognitive status using the MMSE score. The MoCA score shows sex differences in naming, abstraction, and verbal fluency domains and revealed a higher percentage of severe cognitive disorders (up to 50%) compared to the MMSE score (7-9%). In male and female candidates for CABG, age and comorbidities are negatively associated with cognitive status.

scholarly journals Cognitive Functions and Depression in Patients with Irritable Bowel Syndrome

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Per G. Farup ◽  
Knut Hestad
Keyword(s):  
Irritable Bowel Syndrome ◽  
Cognitive Deficits ◽  
Cognitive Functions ◽  
Verbal Fluency ◽  
Neuropsychological Tests ◽  
Depression Scale ◽  
Rome Iii Criteria ◽  
Psychomotor Speed ◽  
Rome Iii ◽  
Irritable Bowel

Background. Irritable bowel syndrome (IBS) is associated with depression and depression with impaired cognitive functions. The primary aim was to study associations between depression and cognitive functions in patients with IBS.Methods. IBS (according to the Rome III criteria), cognitive functions (evaluated with a set of neuropsychological tests), and depression (measured with Beck Depression Inventory II and Montgomery-Åsberg Depression Scale) were analysed in patients with idiopathic depression and in patients with unspecified neurological symptoms.Results. 18 and 48 patients with a mean age of 47 and 45 years were included in the “Depression” and “Neurological” group, respectively. In the “Depression” group, the degree of depression was significantly higher in patients with IBS than in those without. Depression was associated with impaired cognitive function in 6 out of 17 neuropsychological tests indicating reduced set shifting, verbal fluency, attention, and psychomotor speed. IBS was statistically significantly associated with depression but not with any of the tests for cognitive functions.Conclusions. IBS was associated with depression but not with impaired cognitive functions. Since the idiopathic depression was associated with cognitive deficits, the findings could indicate that the depression in patients with IBS differs from an idiopathic depression.

scholarly journals Cognitive function of pregnant women: the problem of postoperative cognitive dysfunction in women after labor

2020 ◽  
Vol 69 (1) ◽  
pp. 7-16
Author(s):  
Aleksey V. Shchegolev ◽  
Dmitry M. Shirokov ◽  
Oksana A. Chernykh ◽  
Irina V. Vartanova ◽  
Maria V. Khrabrova
Keyword(s):  
Cognitive Function ◽  
Pregnant Women ◽  
Cognitive Dysfunction ◽  
Cognitive Functions ◽  
Postoperative Cognitive Dysfunction ◽  
Depression Scale ◽  
Cognitive Status ◽  
Reproductive Age ◽  
Memory And Attention ◽  
The Impact

The problem of postoperative cognitive dysfunction is relevant in obstetrics due to the initial psychophysiological state of a pregnant woman and the high frequency of abdominal delivery everywhere. When choosing the optimal method of anesthesia for a cesarean section, which would minimally affect cognitive functions, it is necessary to consider the impact of anesthesia on the memory and attention of puerperas, as well as their initial cognitive status. To assess memory and attention in women of reproductive age, in our opinion, the most appropriate tests are the MoCA-test, Benton test, Wechsler test, hospital anxiety and depression scale, and a self-assessment questionnaire. These tests are recommended by psychophysiologists and have proven themselves to be well applied in daily clinical practice. Standard test kits with a formalized (quantitative) evaluation of the results allow a rapid assessment of several cognitive functions in a limited time. This review article presents the problem of the cognitive function of pregnant women and postoperative cognitive dysfunction during pregnancy.

Effect of age on outcome in patients with cerebral stroke

2020 ◽  
pp. 41-45
Author(s):  
G. R. Kuchava ◽  
E. V. Eliseev ◽  
B. V. Silaev ◽  
D. A. Doroshenko ◽  
Yu. N. Fedulaev
Keyword(s):  
Ischemic Stroke ◽  
Neurological Deficit ◽  
Neurological Status ◽  
Statistical Correlation ◽  
Multiple Organ ◽  
The Body ◽  
Social Adaptation ◽  
Cerebral Stroke ◽  
Septic Complications ◽  
Risk Of Death

The aim of the study was to assess the course and outcome of cerebral infarction, depending on the age factor and duration of stay in the neuroblock. Materials and methods: a dynamic observation of 494 patients, men and women, aged 38–84 years with acute ischemic stroke of hemispheric localization, which were divided into the three groups depending on age, was performed. Group 1 – younger than 60 years old, group 2–60–70 years old, group 3 – older than 60 years. All patients underwent standard therapy, according to the recommendations for the treatment of ischemic stroke. The patients underwent comprehensive clinical and instrumental monitoring, which included assessment of somatic and neurological status according to the NIH‑NINDS scales at 1st, 3rd, 10th days and at discharge or death; assessment of the level of social adaptation according to the Bartel scale on 1st, 3rd, 10th days and at discharge, clinical and biochemical blood tests, computed tomography of the brain. Assessment of the quality of therapy was carried out according to specially developed maps using methods of statistical correlation analysis. Results: the most pronounced positive dynamics of neurological status was in the 1st group of patients. The regression of neurological deficit in the 2nd group was worse. The minimal dynamics of neurological deficit was in the 3rd group of patients with cerebral stroke. Most often, the death of patients with cerebral stroke occurred from the development of multiple organ disorders. Conclusions: patients over 70 years of age have the greatest risk of death, due to: a decrease in the reactivity of the body, the presence of initially severe concomitant somatic pathology in patients with admission to hospital; accession of secondary somatic and purulent‑septic complications.

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