EXERCISE, BLOOD PRESSURE AND MORTALITY: FINDINGS OF EIGHT YEARS OF FOLLOW-UP

ABSTRACT Introduction: In the last decades, unhealthy habits, such as low levels of physical activity and poor diet, have increased. Consequently, the prevalence of cardiovascular diseases and mortality has increased significantly among adults. However, it is known that regular physical exercises help to improve health outcomes. Thus, the aim of this study was to analyze the effects of eight years of regular participation in an exercise program on blood pressure and mortality in the Brazilian public health system. Methods: The sample consisted of 34 participants with hypertension and/or type II diabetes who were followed up for eight years. They were paired by age, body mass index and chronic disease in two groups: exercise and control. During the follow-up period, medical records were used to assess systolic and diastolic blood pressure, as well as number of medical appointments and the occurrence of deaths. Results: In the follow-up period, five participants died in the control group and none in the exercise group. The Kaplan-Meier analysis identified 29.4% lower mortality among active participants (Fisher's exact test with p = 0.044). The number of medical appointments and the values of diastolic blood pressure were significantly lower for active participants. Conclusion: After a follow-up of eight years, participants in the exercise group attended fewer medical appointments, had better blood pressure control and a lower occurrence of deaths.

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Effects of aerobic plus explosive power exercises on bone remodeling and bone mineral density in young men

Turkish Journal of Biochemistry ◽

10.1515/tjb-2016-0130 ◽

2017 ◽

Vol 43 (1) ◽

pp. 40-48

Author(s):

Veysi Çay ◽

Gurbuz Buyukyazi ◽

Cevval Ulman ◽

Fatma Taneli ◽

Yeliz Doğru ◽

...

Keyword(s):

Maximal Oxygen Consumption ◽

Exercise Program ◽

Exercise Group ◽

Risk Level ◽

Control Group ◽

Maximal Heart Rate ◽

Mineral Density ◽

Explosive Power ◽

Before And After ◽

And Control

AbstractObjectives:This study aims to examine effects of aerobic jogging and explosive power exercises on body composition, maximal oxygen consumption (MaxVOMaterials and methods:Thirty seven healthy males were divided into exercise group (EG, n=19) and control group (CG, n=18). EG completed 10 weeks of outdoor aerobic (jogging at 60–70% maximal heart rate reserve starting from 20 min steadily increasing up to 28 min) and explosive power exercises (in 2–3 sets, with maximum repetitions lasting 15 s), 3 times per week. All measurements were taken before and after the exercise program. BMD was measured via dual energy X-ray absorptiometry (DEXA).Results:Body mass index (p<0.001) significantly decreased; MaxVOConclusion:Performing our outdoor exercise program in spring months might have an important role in the significant increase (9 vs. 22 ng/mL) in mean vitamin D level, which reached above the fracture risk level of 20 ng/mL.

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PERBEDAAN PENURUNAN TEKANAN DARAH PRA LANSIA PRE HIPERTENSI YANG DIBERI JUS TOMAT (Lycopersicum grandifilum)

JURNAL MEDIA KESEHATAN ◽

10.33088/jmk.v10i2.337 ◽

2018 ◽

Vol 10 (2) ◽

pp. 152-158

Author(s):

Hari Yani Fadillah

Keyword(s):

Blood Pressure ◽

Treatment Group ◽

Block Design ◽

Pressure Control ◽

Tomato Juice ◽

Control Group ◽

Randomized Block Design ◽

Before And After ◽

Blood Pressure Treatment ◽

And Control

The research aims to know the effect of tomato juice on blood pressure in pre-elderly pre hypertension at Posbindu Puskesmas Nusa Indah Bengkulu City.The design of research was a quasi experiment include pre test post test. This population was all patients posbindu aged 45-59 years. Sampling of this research randomized block design of one factorial were 6 samples divided into treatment and control group. The data which have been analyzed using univariate and bivariate. From this research were obtained the results such as the mean of sistole blood pressure before and after intervention in treatment group p = 0,273 and diastole p = 0,27. Mean systole blood pressure control group p = 0.060 and diastole p = 2.14. Distribution of tomato juice (Lycopersicum grandifilum) did not given affect the decrease in blood pressure of systole diastole before and after intervention in pre-elderly pre hypertension. Whereas the difference in mean systole of blood pressure treatment and control group p = 0.935 and diastolic of blood pressure p = 0.678. There ware not difference in mean of blood pressure in the tomato juice treatment group and control of Vitamin C. The result concluded there were not effect of tomato juice (Lycopersicum grandifilum) on systolic of blood pressure in pre-elderly pre hypertension at Posbindu Puskesmas Nusa Indah Bengkulu City.

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Serum Level Changes of Neurotrophin-3 after Performing Diabetic Foot Exercise in Diabetic Neuropathy

International Journal of Public Health Science (IJPHS) ◽

10.11591/.v4i4.4750 ◽

2015 ◽

Vol 4 (4) ◽

pp. 304

Author(s):

Tri Wahyuliati ◽

Agung Pranoto ◽

Samekto Wibowo

Keyword(s):

Blood Pressure ◽

Serum Level ◽

Diabetic Neuropathy ◽

Systolic Blood Pressure ◽

Diastolic Blood Pressure ◽

Diabetic Foot ◽

Serum Levels ◽

Exercise Group ◽

Control Group ◽

Post Test

The research aimed to determine the pattern of changes in serum levels of NT-3 in the improvement of diabetic neuropathy, after doing diabetic foot exercise. A true experimental study with randomaized pre – post test control trial. A total of 36 subjects meeting the inclusion and exclusion criteria were included in the exercise group or the control one with age matched systematic random sampling method. Exercise group had a significant improvement on the score of ABI (p.0.002), systolic blood pressure (p.0.014), diastolic blood pressure (p.0.055), DNS (p.0.01), DNE (p.0.001) and increased of serum level of NT-3 (p.0.049). Control group had result respectively on ABI (p.0.131), systolic blood pressure (p.0.668), diastolic blood pressure (p.0.216), DNS (p.1.00), DNE (p.0.543), and increase of NT-3 (p.0.264). The comparation results of the two groups had a significant different on the score of ABI (p.0.01), systolic blood pressure (p.0.01), diastolic blood pressure (p.0.01), DNS (p.0.01), DNE (p.0.01), and increased of NT-3 (p.0.01). Diabetic foot exercise had a peripheral affect on a clinically significant improvement based on ABI scores, systolic and diastolic blood pressure, DNS and DNE, and increase of serum level of NT-3.

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Prevention of Fungal Peritonitis with Nystatin Prophylaxis in Patients Receiving CAPD

Peritoneal Dialysis International ◽

10.1177/089686080702700512 ◽

2007 ◽

Vol 27 (5) ◽

pp. 531-536 ◽

Cited By ~ 24

Author(s):

Ping-Nam Wong ◽

Kin-Yee Lo ◽

Gensy M.W. Tong ◽

Shuk-Fan Chan ◽

Man-Wai Lo ◽

...

Keyword(s):

Antibiotic Therapy ◽

Large Scale ◽

Controlled Trial ◽

Statistical Significance ◽

Control Group ◽

Fungal Peritonitis ◽

Kaplan Meier ◽

Prospective Randomized Controlled Trial ◽

And Control

Objective Fungal peritonitis (FP) is a serious complication of continuous ambulatory peritoneal dialysis (CAPD), being associated with significant morbidity and mortality. The role of nystatin prophylaxis during antibiotic therapy in the prevention of FP remains controversial, especially in programs with a modest or low baseline FP rate. The aim of the present study was to evaluate the effect of nystatin prophylaxis on the occurrence of FP in programs with a relatively modest baseline FP rate. Patients and Methods Incident and prevalent patients receiving CAPD between April 1995 and April 2005 at our center were included and divided into 2 groups. The control group included 320 patients (total follow-up 8875 patient-months) being treated without nystatin before October 1999; the nystatin group included 481 patients (total follow-up 13725 patient-months) being treated after October 1999. Nystatin tablets (500000 units, 4 times per day) were given orally during whatever use of antibiotics to cover the whole course of antibiotic therapy. Occurrence of FP and antibiotic-related FP (AR-FP) in patients with and without nystatin prophylaxis was compared. Results The two groups were of similar age but the nystatin group had a significantly higher percentage of diabetics. In addition, the nystatin group had a higher proportion of patients using disconnecting twin-bag exchange systems and had a significantly lower peritonitis rate compared with the control. There were 13 and 14 episodes of FP in the nystatin and control groups respectively. The fungal peritonitis rate of the nystatin group was slightly lower than that of the control group (0.011 vs 0.019 per patient-year) but it did not reach statistical significance. There was, however, a significant decrease in the incidence and proportion of AR-FP in the nystatin group compared with the control group, which persisted even after adjustment for the peritonitis rate. Kaplan–Meier analysis further demonstrated significantly better AR-FP-free survival in the nystatin group compared with the control group. No significant side effects were observed for nystatin. Subgroup analyses in patients of the 2 different connecting systems revealed a similar but nonsignificant trend toward reduction of AR-FP in patients given nystatin prophylaxis. Conclusion Oral nystatin prophylaxis might prevent the occurrence of AR-FP in CAPD patients, resulting in a trend toward reduction in the incidence of FP even in programs with a modest baseline FP rate. A large scale, prospective, randomized controlled trial is needed to further examine this issue.

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Arterial Stiffness Response to Regular Aerobic Training in Hypercholesterolemia Patients

International Journal of Sports Medicine ◽

10.1055/a-0574-3096 ◽

2018 ◽

Vol 39 (06) ◽

pp. 413-418 ◽

Cited By ~ 1

Author(s):

Guanghui Liu ◽

Jiasheng Zhao ◽

Yang Cao

Keyword(s):

Oxidative Stress ◽

Arterial Stiffness ◽

Exercise Program ◽

Exercise Group ◽

Control Group ◽

Dietary Recommendations ◽

Exercise Tests ◽

Important Pathway ◽

And Oxidative Stress

AbstractPhysical exercise increase is confirmed as a fundamental treatment for hypercholesterolemia patients, but the effect on the arterial stiffness and oxidative stress is still unclear. 74 hypercholesterolemia patients were divided into 2 groups. The exercise group received dietary recommendations and a 3-month exercise program, prescribed according to their first cardiopulmonary exercise tests(CPET), while the control group only received dietary recommendations. All patients underwent blood tests, CPET and brachial-ankle pulse wave velocity (baPWV) studies at enrollment and at 3 months’ follow-up. At the end of 3 months, there was no change in total cholesterol (TC) level in either group. However, in the exercise group, we found maximal exercise parameters increased and baPWV values declined. Meanwhile, there were significant changes in the level of malondialdehyde, 8-isoprostane-F2α and superoxide dismutase. Moreover, the change of baPWV was positively correlated with the change of 8-isoprostane-F2α (r=0.36, P<0.01). In the control group, no change in baPWV or oxidative biomarker was observed. Our findings suggested that regular aerobic exercise could lessen arterial stiffness in hypercholesterolemia patients, even in the context of no obvious TC decrease. During this process, favorable adjustment in oxidative stress might be an important pathway, which remains to be further explored.

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Detraining Effects on Musculoskeletal Parameters in Early Postmenopausal Osteopenic Women: 3-Month Follow-Up of the Randomized Controlled ACTLIFE Study

Calcified Tissue International ◽

10.1007/s00223-021-00829-0 ◽

2021 ◽

Author(s):

Wolfgang Kemmler ◽

Michael Hettchen ◽

Matthias Kohl ◽

Marie Murphy ◽

Laura Bragonzoni ◽

...

Keyword(s):

Exercise Intervention ◽

Exercise Program ◽

Exercise Group ◽

Frequent Pattern ◽

Control Group ◽

Group Exercise ◽

Mineral Density ◽

Leg Extension ◽

Randomized Controlled

AbstractPeriods of absence from supervised group exercise while maintaining physical activity might be a frequent pattern in adults' exercise habits. The aim of the present study was to determine detraining effects on musculoskeletal outcomes after a 3-month detraining period in early post-menopausal, osteopenic women. Due to the COVID-19 pandemic, we terminated the 18-month randomized controlled ACTLIFE exercise intervention immediately after the 13-month follow-up assessment. This put an abrupt stop to the high-intensity aerobic and resistance group exercise sessions undertaken three times per week by the exercise group (EG: n = 27) and the gentle exercise program performed once per week for the attention control group (CG: n = 27); but both groups were permitted to conduct individual outdoor activity for the 3-month lock-down period. Study endpoints were lean body mass (LBM), bone mineral density (BMD) at the lumbar spine (LS), maximum hip-/leg extension strength and power. Detraining-induced reductions of LBM, hip/leg strength and power (but not BMD-LS) were significantly greater (p < 0.001 to p = 0.044) compared with the CG. Significant exercise effects, i.e. differences between EG and CG, present after 13 months of exercise, were lost after 3 months of detraining for LBM (p = 0.157) and BMD-LS (p = 0.065), but not for strength (p < 0.001) and power (p < 0.001). Of note, self-reported individual outdoor activities and exercise increased by about 40% in both groups during the lock-down period. Three months' absence from a supervised group exercise protocol resulted in considerable detraining effects for musculoskeletal parameters. Thus, exercise programs for adults should be continuous rather than intermittent.Trial registration number: ClinicalTrials.gov: NCT04420806, 06.05.2020.

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The effect of an exercise intervention on haemodynamic variables in pregnant women

ENTRAMADO ◽

10.18041/1900-3803/entramado.2.6697 ◽

2020 ◽

Vol 16 (2) ◽

pp. 264-274

Author(s):

Blanca Cecilia Salazar-Contreras

Keyword(s):

Pregnant Women ◽

Exercise Intervention ◽

Diastolic Pressure ◽

Systolic Pressure ◽

Exercise Group ◽

Interquartile Range ◽

Control Group ◽

Exercise In Pregnancy ◽

And Control

Objective: This study evaluated the effect of exercise on heart rate (HR), systolic pressure (SBP), and diastolic pressure (DBP) at different gestational ages during pregnancy. Methods: The exercise intervention and control groups from a previous multi-intervention clinical trial were used. Ninety-two pregnant women were analysed [control group: n = 48; exercise group: n = 44]. The outcome variables were the percentage change in SBP, DBP, and HR during follow-up intervals (16–20 weeks, 20–24 weeks, 24–28 weeks, and 28–32 weeks).Results: resting HR showed a lower increase in the exercise group than in the control group during the interval of gestational weeks 16-20 (p=0.011) [Median Interquartile range: 8.8 (0 to 27.9) control group; 2.2 (-6.9 to 8.1) exercise group]. During this same interval SBP decreased in both control and exercise groups, with more decrease in the control group (P<0.05) [Median Interquartile range: -4.29 (-11.1 to 1.9) control group; -0.89 (-4.76 to 6.36)]. Conclusion: Aerobic exercise in pregnancy significantly attenuated increase of resting HR at the beginning of the second trimester of pregnancy.

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Effectiveness and safety of indapamide sustained-release in the treatment of post partial hypertension

Systemic Hypertension ◽

10.26442/sg29065 ◽

2015 ◽

Vol 12 (2) ◽

pp. 24-28

Author(s):

I R Gaisin ◽

A S Iskchakova ◽

L V Shilina ◽

N I Maksimov ◽

Zh V Vavilkina ◽

...

Keyword(s):

Blood Pressure ◽

Post Partum ◽

Pressure Control ◽

Lifestyle Modifications ◽

Open Label ◽

Significant Difference ◽

Hypertensive Disorders In Pregnancy ◽

Nursing Mothers ◽

And Control

Background. Hypertensive disorders in pregnancy have been recognized as an important risk factor for atherosclerotic CVD in women. Therefore, lifestyle modifications, regular blood pressure control, and control of metabolic factors are recommended after delivery, to avoid complications in subsequent pregnancies and to reduce maternal cardiovascular risk in the future. There are no uniform recommendations for the treatment of post partial hypertension (HT) yet.Methods. In a case-control, open-label 1-year study, 54 post-partum hypertensive women (aged 22-38 years; body mass index 26.7±3.8 kg/m2; 18 with previous pre-eclampsia, 18 pre-existing HT, 18 pre-existing HT plus superimposed pre-eclampsia) were studied. Nursing mothers (n=27) received adjusted-dose methyldopa (Egis) 500-2000 mg daily, 27 non-feeding women received indapamide SR (Servier) 1.5 mg daily. No significant differences observed between two groups at baseline.Results. After comprehensive follow-up, clinical blood pressure was not found to differ substantially between indapamide and methyldopa groups (124.8±3.2/83.2±2.1 mmHg vs 125.3±3.8/81.5±2.9 mmHg respectively; p =NS), but indapamide significantly better improved diurnal BP patterns. No maternal adverse effects were registered in both groups, except for sleepiness and bad mood in 18.5% of methyldopa patients. There was a significant difference in weight reduction, in favour of indapamide (-11.3 kg vs -2.7 kg; p =0.032), as well as in decrease of microalbuminuria (-189.2 mg/24 h vs -51.4 mg/24 h; p

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Pengaruh Do’a terhadap Tekanan Darah pada Pasien Gagal Ginjal Kronis (GGK) Pre-Hemodialysis

Jurnal Keperawatan Silampari ◽

10.31539/jks.v2i1.379 ◽

2018 ◽

Vol 2 (1) ◽

pp. 343-355

Author(s):

Hilda Nur Afriani ◽

Rohman Azzam ◽

Busrja M.Nur

Keyword(s):

Blood Pressure ◽

Diastolic Blood Pressure ◽

Reduce Blood Pressure ◽

T Test ◽

Control Group ◽

Test Results ◽

Hospital Data ◽

Control Groups ◽

Before And After ◽

And Control

Objective of this study was to determine the effect of prayer on pre-hemodialysis blood pressure of CRF patients in the hemodialysis room of the Jakarta Islamic Hospital. Data collection was done through purposive sampling. This study examined 32 respondents. The results of the study indicated there was a decrease in blood pressure in the intervention and control groups before and after giving prayers on systolic and diastolic blood pressure. The results of the paired t-test before and after being given prayers in the intervention and control groups produced a sig value of <0.05 in systolic and diastolic blood pressure, which means that there were differences before and after giving prayers. The unpaired t-test results in the intervention and control groups of systolic blood pressure produced a sig value> 0.05, which means that there was no difference between the intervention and control group. On the contrary, diastolic blood pressure produced a sig value <0.05, which means that there were differences between the intervention and control group. Finally, it can be concluded that the provision of a prayer intervention in pre-hemodialysis was effectively proven to reduce blood pressure. Keywords : chronic kidney disease, blood pressure, prayer.

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