scholarly journals First case of canine visceral leishmaniasis in the midwestern of Santa Catarina State, Brazil

2022 ◽  
Vol 82 ◽  
Author(s):  
A. O. Pinto ◽  
D. Carvalho ◽  
C. Frizzo ◽  
K. Lopes ◽  
G. B. Tessari ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Peripheral Blood ◽  
Clinical Symptoms ◽  
Control Measures ◽  
Epidemiological Surveillance ◽  
Enzyme Linked Immunosorbent Assay ◽  
Canine Visceral Leishmaniasis ◽  
Santa Catarina ◽  
First Case ◽  
Santa Catarina State

Abstract Canine visceral leishmaniasis (CVL) caused by Leishmania (Leishmania) infantum is transmitted by phlebotomine sandflies and a major zoonotic disease in Brazil. Due to the southward expansion of the disease within the country and the central role of dogs as urban reservoirs of the parasite, we have investigated the occurrence of CVL in two municipalities Erval Velho and Herval d’Oeste in the Midwest region of Santa Catarina state. Peripheral blood samples from 126 dogs were collected in both cities and tested for anti-L. infantum antibodies by indirect enzyme-linked immunosorbent assay (ELISA) and indirect immunofluorescence reaction (IIF) and for the presence of parasite DNA by polymerase chain reaction (PCR) in peripheral blood. From examined dogs, 35.71% (45/126) were positive for at least one of the three tests and two (1.6%) were positive in all performed tests. Twelve dogs (9.5%) were positive for both ELISA and IIF, while 21 dogs were exclusively positive for ELISA (16.7%), and 15 (11.9%) for IIF. L. infantum k-DNA was detected by PCR in 9 out of 126 dogs (7.1%) and clinical symptoms compatible with CVL were observed for 6 dogs. Taken together, these results indicate the transmission of CVL in this region, highlighting the needs for epidemiological surveillance and implementation of control measures for CVL transmission in this region.

scholarly journals The first case of canine visceral leishmaniasis in the southern region of Santa Catarina, an emerging focus of visceral leishmaniasis in Brazil: regional report or reflection of the reality of a country?

2021 ◽  
Vol 10 (17) ◽  
pp. e167101724326
Author(s):  
Diego Soares Leote ◽  
Dayane Borba da Silva ◽  
Paula Fassicolo Variza ◽  
Joice Guilherme de Oliveira ◽  
Cyntia Michielin Lopes ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Cross Sectional Study ◽  
Urban Environments ◽  
High Rate ◽  
Leishmania Infection ◽  
Neglected Diseases ◽  
Canine Visceral Leishmaniasis ◽  
Santa Catarina ◽  
Cross Sectional ◽  
First Case

Visceral leishmaniasis is among the most neglected diseases in the world and especially affects poor populations of some developing or underdeveloped countries, with human disease being a factor in the occurrence of thousands of deaths every year. Visceral leishmaniasis affect domestic dogs, main reservoirs of the Leishmania parasite in urban environments. Thus, the aim of this study was to analyze the prevalence of canine visceral leishmaniasis in two non-endemic municipalities located in southern Santa Catarina, as well as to identify the main risk factors for infection in dogs. A cross-sectional study was carried out with dogs living in two Zoonoses Control Centers located in the cities of Tubarão and Criciúma. Blood samples were collected and analyzed by real-time PCR for detection of Leishmania infection. Clinical examination and evaluation of the characteristics of the canine population were also carried out. A total of 107 dogs were evaluated, of which 19% were positive for Leishmania, and 85% of the positive cases were asymptomatic. In conclusion, we highlight the detection of cases of canine visceral leishmaniasis in two cities that had not yet reported cases. The high rate of positive asymptomatic animals suggests the maintenance of the parasite in the environment.

scholarly journals Outbreak of autochthonous canine visceral leishmaniasis in Santa Catarina, Brazil

2013 ◽  
Vol 33 (4) ◽  
pp. 490-496 ◽  
Author(s):  
Mário Steindel ◽  
Álvaro Menin ◽  
Tatiane Evangelista ◽  
Patrícia H. Stoco ◽  
Mariel A. Marlow ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Control Measures ◽  
Health Concern ◽  
Canine Visceral Leishmaniasis ◽  
Southern Brazil ◽  
Santa Catarina ◽  
Control Center ◽  
Spleen And Lymph Nodes ◽  
And Control ◽  
Autochthonous Transmission

The present study reports the first outbreak of autochthonous canine visceral leishmaniasis in Florianópolis, Santa Catarina, southern Brazil. Following the report of two cases of CVL, the Control Center of Zoonotic Diseases conducted a serological survey by ELISA and IFAT assays in seven districts of the Santa Catarina Island. Eleven seropositive dogs of autochthonous transmission were used in the present study. Infection by Leishmania sp. was confirmed by parasitological examination of bone marrow, liver, spleen and lymph nodes, culture in Schneider's medium and PCR. Leishmania sp. isolates were characterized by PCR-RFLP and hybridization with specific probes, allowing for the identification of Leishmania infantum. Autochthonous transmission of this disease in an area with high tourist traffic presents a major public health concern and signifies the emergence of an important zoonosis in southern Brazil. Therefore, the implementation of surveillance and control measures is imperative to prevent the spread of the disease among the canine population as well as transmission to the human population.

scholarly journals High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil – A Phase II study

2018 ◽  
Vol 12 (10) ◽  
pp. e0006871 ◽  
Author(s):  
Lairton Souza Borja ◽  
Lívia Brito Coelho ◽  
Matheus Silva de Jesus ◽  
Artur Trancoso Lopo de Queiroz ◽  
Paola Alejandra Fiorani Celedon ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Phase Ii ◽  
Phase Ii Study ◽  
High Accuracy ◽  
Elisa Test ◽  
Control Measures ◽  
Canine Visceral Leishmaniasis

Comparative evaluation of enzyme-linked immunosorbent assay based on crude and purified antigen in the diagnosis of canine visceral leishmaniasis in symptomatic and oligosymptomatic dogs

2008 ◽  
Vol 157 (3-4) ◽  
pp. 175-181 ◽  
Author(s):  
Teresinha Cristina Cândido ◽  
Sílvia Helena Venturoli Perri ◽  
Tatiana de Oliveira Gerzoschkwitz ◽  
Maria Cecília Rui Luvizotto ◽  
Valéria Marçal Felix de Lima
Keyword(s):  
Visceral Leishmaniasis ◽  
Immunosorbent Assay ◽  
Comparative Evaluation ◽  
Enzyme Linked Immunosorbent Assay ◽  
Canine Visceral Leishmaniasis ◽  
Purified Antigen

scholarly journals Autochthonous Chagas' disease in Santa Catarina State, Brazil: report of the first case of digestive tract involvement

2003 ◽  
Vol 36 (5) ◽  
pp. 609-612 ◽  
Author(s):  
Felipe Antonio Boff Maegawa ◽  
Ernesto Francisco Damerau ◽  
Ingrid Thais Beltrame-Botelho ◽  
Aldemar Lopes ◽  
Priscilla Emmanuelle-Machado ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Digestive Tract ◽  
Chagas Disease ◽  
Buffy Coat ◽  
Immunological Methods ◽  
Santa Catarina ◽  
First Case ◽  
Tract Involvement ◽  
Cruzi Infection ◽  
Santa Catarina State

We report the first case of digestive tract pathology (megaesophagus) determined by Trypanosoma cruzi infection in Santa Catarina State, southern Brazil. A 63-year- old female had presumptive clinical diagnosis of Chagas' disease, which was confirmed by imaging (endoscopy and esophagogram) and immunological methods. Further molecular diagnosis was carried out with esophagus and blood samples collected during corrective surgery. Polymerase chain reaction tested positive for Trypanosoma cruzi in both esophagus and buffy coat samples.

scholarly journals Correction: High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil—A Phase II study

2020 ◽  
Vol 14 (5) ◽  
pp. e0008346
Author(s):  
Lairton Souza Borja ◽  
Lívia Brito Coelho ◽  
Matheus Silva de Jesus ◽  
Artur Trancoso Lopo de Queiroz ◽  
Paola Alejandra Fiorani Celedon ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Phase Ii ◽  
Phase Ii Study ◽  
High Accuracy ◽  
Elisa Test ◽  
Control Measures ◽  
Canine Visceral Leishmaniasis

scholarly journals Leishmania (infantum) chagasi in canine urinary sediment

2015 ◽  
Vol 24 (1) ◽  
pp. 92-94 ◽  
Author(s):  
Ivete Lopes de Mendonça ◽  
Joilson Ferreira Batista ◽  
Leucio Camara Alves
Keyword(s):  
Bone Marrow ◽  
Clinical Symptoms ◽  
High Sensitivity ◽  
Enzyme Linked Immunosorbent Assay ◽  
Canine Visceral Leishmaniasis ◽  
Serological Tests ◽  
Urine Sediment ◽  
Urinary Sediment ◽  
Control Center ◽  
Veterinary Hospital

Canine visceral leishmaniasis (CVL) is difficult to diagnosis, mainly due to the presence of asymptomatic animals, the diversity of clinical symptoms and the difficulty in obtaining diagnostic evidence of high sensitivity and specificity. The purpose of this study was to diagnose CVL in urinary sediment of 70 dogs of different breeds, sexes and ages from the veterinary hospital of the Federal University of Piauí and Zoonosis Control Center of Teresina, Brazil. The serological tests were TR DPP® for CVL and enzyme-linked immunosorbent assay (ELISA) for CVL, parasitological exams of bone marrow and lymph nodes and urine sediment cultures. Leishmania was detected in the bone marrow and/or lymph node of 61.0% of the animals (43/70), and urine sediment culture was positive in 9.30% (4/43) of these animals. In the serological exams, 70.0% (49/70) were reactive using the DPP and 78.2% (55/70) were reactive using ELISA. The goal of this study was to diagnose the presence of L. (infantum) chagasi in a culture of urinary sediment.

scholarly journals Emergence of Lassa Fever Disease in Northern Togo: Report of Two Cases in Oti District in 2016

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Akouda Akessiwe Patassi ◽  
Dadja Essoya Landoh ◽  
Agballa Mebiny-Essoh Tchalla ◽  
Wemboo Afiwa Halatoko ◽  
Hamadi Assane ◽  
...  
Keyword(s):  
Health Professionals ◽  
Ebola Virus ◽  
Clinical Symptoms ◽  
Fatal Outcome ◽  
Delayed Diagnosis ◽  
Hemorrhagic Fever ◽  
Lassa Fever ◽  
Control Measures ◽  
Infection Prevention And Control ◽  
First Case

Background. Lassa fever belongs to the group of potentially fatal hemorrhagic fevers, never reported in Togo. The aim of this paper is to report the first two cases of Lassa fever infection in Togo. Case Presentation. The two first Lassa fever cases occurred in two expatriate’s health professionals working in Togo for more than two years. The symptoms appeared among two health professionals of a clinic located in Oti district in the north of the country. The absence of clinical improvement after antimalarial treatment and the worsening of clinical symptoms led to the medical evacuation. The delayed diagnosis of the first case led to a fatal outcome. The second case recovered under ribavirin treatment. Conclusion. The emergence of this hemorrhagic fever confirms the existence of Lassa fever virus in Togo. After a period of intensive Ebola virus transmission from 2013 to 2015, this is an additional call for the establishment and enhancement of infection prevention and control measures in the health care setting in West Africa.

scholarly journals Canine visceral leishmaniasis: perception, prevalence, and spatial distribution in municipality of Nossa Senhora do Livramento, Mato Grosso, Brazil

2020 ◽  
Vol 29 (2) ◽  
Author(s):  
Matheus Roberto Carvalho ◽  
Álvaro Felipe de Lima Ruy Dias ◽  
Arleana do Bom Parto Ferreira de Almeida ◽  
Mário Ribeiro Alves ◽  
Adilson Santos Paes ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Visceral Leishmaniasis ◽  
Rapid Test ◽  
Enzyme Linked Immunosorbent Assay ◽  
Canine Visceral Leishmaniasis ◽  
Mato Grosso ◽  
Rural And Urban ◽  
Spatially Distributed ◽  
Control And Prevention ◽  
Leishmania Spp

Abstract The midwest region of Brazil has witnessed an increase in the number of cases of human (HVL) and canine visceral leishmaniasis (CVL). The aim of the present study was to evaluate the population’s perception of these diseases, factors associated with CVL, its spatial distribution, and the prevalence of anti-Leishmania spp. in 385 dogs, determined using a commercially available immunochromatographic rapid test and confirmed using enzyme-linked immunosorbent assay (ELISA). Of the 385 samples, 54 were positive for CVL and confirmed by ELISA, corresponding to a prevalence of 14%. Knowledge of signs of CVL by tutors (p = 0.038); previous occurrence of CVL in the vicinity (p = 0.022); symptomatic dog(s) (p = 0.014), splenomegaly (p = 0.055), and ear ulcer(s) (p = 0.059) were significantly associated with CVL. The results revealed a significant prevalence of CVL spatially distributed in rural and urban contexts. The association between environmentally related variables and perception and the occurrence of CVL underscores the importance of implementing control and prevention strategies primarily focused on environmental management and health education activities.

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