Evaluation of waist circumference to predict general obesity and arterial hypertension in women in Greater Metropolitan Belo Horizonte, Brazil

This study examined the capacity of waist circumference (WC) to identify subjects with overweight (BMI ³ 25) and obesity (BMI ³ 30), in agreement with internationally recommended levels of action. Data were obtained from 791 women, 15-59 years old. After identifying overweight and obesity according to WC values, sensitivity and specificity were calculated to verify whether WC could be a good risk predictor for hypertension. Associations were tested by linear regression and logistic regression, controlling for confounding. WC cut-off points of 80cm and 88cm correctly identified 89.8% and 88.5% of women with overweight and obesity, respectively. Abdominal obesity (WC ³ 88cm) was statistically associated with hypertension in the multivariate analysis (OR = 2.88; 95% CI: 1.77-4.67). Hypertension was identified with a sensitivity of 63.8% and 42.8%, and with a specificity of 68.0% and 83.3%, for WC ³ 80 and ³ 88, respectively. The proposed cut-off points for abdominal obesity can potentially distinguish individuals at risk for future obesity, but has only moderate power to predict individuals with high blood pressure.

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Prevalence of general and abdominal obesity in 2015–2016 and 8-year longitudinal weight and waist circumference changes in adults and elderly: the Tromsø Study

BMJ Open ◽

10.1136/bmjopen-2020-038465 ◽

2020 ◽

Vol 10 (11) ◽

pp. e038465

Author(s):

Ola Løvsletten ◽

Bjarne K Jacobsen ◽

Sameline Grimsgaard ◽

Inger Njølstad ◽

Tom Wilsgaard ◽

...

Keyword(s):

Body Weight ◽

Waist Circumference ◽

Abdominal Obesity ◽

Overweight And Obesity ◽

Repeated Measurements ◽

Secular Change ◽

Longitudinal Analyses ◽

General Obesity ◽

Cross Sectional ◽

Longitudinal Changes

ObjectivesTo describe the prevalence of general (body mass index (BMI) ≥30 kg/m2) and abdominal (waist circumference women >88 cm, men >102 cm) obesity in Tromsø 7 (2015–2016), and the secular change from Tromsø 6 (2007–2008). Furthermore, to study longitudinal changes in body weight and waist circumference from Tromsø 6 to Tromsø 7.SettingA population study in Tromsø, Norway.ParticipantsThe cross-sectional analyses included 20 855 participants in Tromsø 7 (aged ≥40 years) and 12 868 in Tromsø 6 (aged ≥30 years). The longitudinal analyses included 8592 participants with repeated measurements, aged 35–79 in Tromsø 6.Outcome measuresMean age-specific and sex-specific BMI, waist circumference, prevalence of general and abdominal overweight and obesity, as well as longitudinal changes in body weight and waist circumference according to sex and birth cohort.ResultsOver 8 years, the age-adjusted prevalence of general obesity increased (p<0.0001) from 20.1% to 23.0% in women and from 20.7% to 25.2% in men. The age-adjusted prevalence of abdominal obesity did not increase in women (from 54.7% to 53.4%), and the increase in men was modest (from 36.8% to 38.6%, p=0.003). Longitudinal analyses showed an increase in body weight, by 1.1 kg (95% CI 0.9 to 1.2) in women and 0.7 kg (95% CI 0.6 to 0.9) in men, and also waist circumference, by 1.3 cm (95% CI 1.0 to 1.5) in women and 1.4 cm (95% CI 1.2 to 1.6) in men. There were inverse relationships (p<0.001) between age at baseline and change in weight and waist circumference.ConclusionsRepeated cross-sectional analyses showed that the prevalence of general obesity increased, whereas the increase in abdominal obesity was less marked. Longitudinal analyses showed increases in both body weight and waist circumference. The youngest age groups have the largest increase.

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Exposure to Chinese Famine in the Early Life, Adulthood Obesity Patterns, and the Incidence of Hypertension: A 22-Year Cohort Study

Annals of Nutrition and Metabolism ◽

10.1159/000515060 ◽

2021 ◽

pp. 1-7

Author(s):

Yu Wang ◽

Jibin Jin ◽

Yue Peng ◽

Yongjie Chen

Keyword(s):

Blood Pressure ◽

Abdominal Obesity ◽

Current Treatment ◽

Late Childhood ◽

Fetal Life ◽

General Obesity ◽

Antihypertensive Medications ◽

Childhood Exposure ◽

Famine Exposure ◽

Obesity Hypertension

Introduction: Little is known regarding the joint associations of famine exposure and obesity patterns with the incidence of hypertension. Methods: We defined famine exposure cohorts as follows: nonexposure (born between 1962 and 1965), fetal life exposure (born between 1959 and 1961), early childhood exposure (born between 1956 and 1958), midchildhood exposure (born between 1953 and 1955), and late childhood exposure (born between 1949 and 1952). Obesity patterns were defined as follows: G−/A−: subjects without neither general obesity nor abdominal obesity; G+/A− or G−/A+: subjects with either general obesity or abdominal obesity; G+/A+: subjects with both general obesity and abdominal obesity. Hypertension was defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg or current treatment with antihypertensive medications. Results: There were 5,235 individuals participating in this study. In the subjects with general or abdominal obesity, famine exposure was associated with a lower risk of hypertension. In males with G−/A−, famine exposures in the midchildhood (p = 0.048; HR: 0.700; HR 95% CI: 0.491–0.998) and late childhood (p = 0.002; HR: 0.560; HR 95% CI: 0.374–0.840) were associated with a lower incidence of hypertension. Conclusion: The coexistence of famine exposure and obesity patterns was associated with the incidence of hypertension.

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General and central obesity operate differently as predictors of falls requiring medical care in older women: a population-based cohort study in Spain

Age and Ageing ◽

10.1093/ageing/afaa164 ◽

2020 ◽

Author(s):

Ygor Hermenegildo-López ◽

Helena Sandoval-Insausti ◽

Carolina Donat-Vargas ◽

Jose Ramón Banegas ◽

Fernando Rodríguez-Artalejo ◽

...

Keyword(s):

Waist Circumference ◽

Medical Care ◽

Older Women ◽

Abdominal Obesity ◽

Regression Models ◽

Population Based ◽

Normal Weight ◽

General Obesity ◽

Logistic Regression Models ◽

Overweight Women

Abstract Objectives to examine the association of general and abdominal obesity with falls, falls requiring medical care and falls with fractures in older women. Design a population-based prospective cohort of 1,185 women aged ≥60 in Spain, followed up from 2008 to 2010 through 2012. Measures weight, height and waist circumference were measured at baseline using standardised techniques. Participants were classified according to body mass index as normal weight (<25), overweight (25–29.9) and general obesity (≥30). Abdominal obesity was defined as waist circumference >88 cm. In 2012, participants reported the falls experienced in the previous year. Logistic regression models were mutually adjusted for general and abdominal obesity and for main confounders. Results in this cohort of older women, a total of 336 women experienced falls, 168 of them had falls requiring medical care and 64 falls with fractures. For falls, no association was found with general obesity nor abdominal obesity. However, compared with normal weight, overweight women had a decreased risk for falls requiring medical care [odds ratio (OR) 0.57; 95% confidence interval (CI) 0.34–0.94] and for falls with fractures (OR 0.27; 95% CI 0.12–0.63). The corresponding values for general obesity were 0.44 (0.24–0.81) and 0.30 (0.11–0.82). Abdominal obesity was positively associated with falls requiring medical care (OR 1.82; 95% CI 1.12–2.94) and falls with fractures (OR 2.75; 95% CI 1.18–6.44). Conclusions in older women, general obesity may protect from falls requiring medical care and falls with fractures. On the contrary, abdominal obesity increased the risk of suffering from types of falls.

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Effect of Daily Avocado Consumption on Vascular Health in Adults With Abdominal Obesity: A Sub-Study of the Habitual Diet and Avocado Trial, a Randomized Controlled Study

Current Developments in Nutrition ◽

10.1093/cdn/nzab033_010 ◽

2021 ◽

Vol 5 (Supplement_2) ◽

pp. 10-10

Author(s):

Kristin Davis ◽

Kristina Petersen ◽

Penny Kris-Etherton

Keyword(s):

Blood Pressure ◽

Waist Circumference ◽

Abdominal Obesity ◽

Cardiovascular Health ◽

Controlled Study ◽

Group Differences ◽

Control Group ◽

Vascular Health ◽

Randomized Controlled ◽

Habitual Diet

Abstract Objectives To examine the effect of providing 1 avocado per day for consumption over a 6-month period on cardiovascular health compared to habitual dietary intake in individuals with abdominal obesity. Methods The Habitual diet and Avocado Trial (HAT), a multicenter parallel randomized controlled trial, included participants ≥25 years of age with an elevated waist circumference (≥88 cm women; ≥102 cm men). Participants were randomized to either an experimental group (AVO: consumed 1 avocado/day for 6 months) or a control group (HD: consumed < 2 avocados/month for 6 months). At the Pennsylvania State University, University Park (n = 126), vascular health was measured using a SphygmoCor XCEL (AtCor Medical) at baseline and at the end of the study period. Outcomes include central systolic blood pressure (cSBP), central diastolic blood pressure (cDBP), and pulse wave velocity (PWV), a marker of arterial stiffness. Mixed models were used to examine between-group differences in change across 6 months. Results The sample was 77% female (BMI 34 ± 4 kg/m2, waist circumference 105 ± 12 cm). No significant between-group differences in 6-month change were observed for cSBP (AVO: 1.06 mmHg 95% CI − 1.57, 3.69; HD: 0.35 mmHg 95% CI −2.26, 2.96; P = 0.62), cDBP (AVO: 0.07 mmHg 95% CI −1.82, 1.96; HD: −0.91 mmHg 95% CI − 2.79, 0.97; P = 0.34), or PWV (AVO: −0.18 m/s 95% CI −0.53, 0.17; HD: 0.08 m/s 95% CI −0.27, 0.43; P = 0.17). Conclusions Results suggest that providing adults with abdominal obesity 1 avocado per day to consume for 6 months is not associated with a statistically significant improvement in central blood pressure or PWV, compared to adults following their habitual diet. Additional research using larger samples and longer intervention periods is needed to clarify whether habitual avocado consumption yields clinically significant benefits to cardiovascular health. Funding Sources Hass Avocado Board and the National Center for Advancing Translational Sciences, National Institutes of Health (1UL1TR002014-01).

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Association between dietary diversity with overweight and obesity: A cross-sectional study conducted among pastoralists in Monduli District in Tanzania

PLoS ONE ◽

10.1371/journal.pone.0244813 ◽

2021 ◽

Vol 16 (1) ◽

pp. e0244813

Author(s):

Ahmed Gharib Khamis ◽

Julius Edward Ntwenya ◽

Mbazi Senkoro ◽

Sayoki Godfrey Mfinanga ◽

Katharina Kreppel ◽

...

Keyword(s):

Abdominal Obesity ◽

Dietary Diversity ◽

Cross Sectional Study ◽

Careful Consideration ◽

Overweight And Obesity ◽

Sectional Study ◽

General Obesity ◽

Cross Sectional ◽

Monduli District ◽

Arusha Region

Background The prevalence of overweight and obesity is rising at a rapid pace and is associated with negative health consequences like cardiovascular diseases, type 2 diabetes and cancer. Obesity is a multifactorial problem that develops mainly from lifestyle factors including physical inactivity and poor dietary intake. Dietary diversity is a simplified method for assessing the adequacy and quality of diet and is associated with nutritional need and overall health status. Therefore, we conducted this study to synthesize the associations between consumption of a diversified diet and overweight/ obesity among adults living in pastoral communities in Monduli district in Tanzania. Methods This was a cross-sectional study conducted among 510 adults aged ≥ 18 years old in the Monduli district, Arusha region in Tanzania. We conducted face-to-face interviews to collect information about socio-demographic characteristics, 24-hours dietary recall, and anthropometric measurements. The dietary diversity score (DDS) was constructed and used to determine the diversity of the diet consumed. We performed the multivariate Poisson regressions to determine the prevalence ratio (PR) with 95% confidence intervals (CI). The dependent variables were overweight and general obesity as measured by body mass index (BMI), abdominal obesity measured by waist-hip ratio (WHR) and waist circumference (WC). Results The prevalence of general obesity based on BMI was 20.2% (95%CI; 16.9–23.9), abdominal obesity based on WHR was 37.8% (95%CI; 33.7–42.1), and WC was 29.1% (95%CI; 25.2–33.1). More than half (54.3%) of the participants consumed an adequate dietary diversity (DDS ≥4). After adjustment for potential confounders, the prevalence of abdominal obesity by WHR decreased with higher DDS among male (APR = 0.42; 95% CI, 0.22–0.77) and female participants (APR = 0.63; 95% CI, 0.41–0.94). There were inconsistent positive associations between DDS and prevalence of overweight and general obesity among male and female. There was no association between DDS and abdominal obesity by WC. Conclusion More than half of the pastoralists have consumed an adequate diversified diet. Given the inconsistent findings on associations between dietary diversity and obesity measures, this study suggests that targeting dietary diversity as an overweight/obesity prevention strategy requires careful consideration.

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Клінічні та фенотипічні патерни у школярів із надлишковою масою тіла та ожирінням

Вісник наукових досліджень ◽

10.11603/2415-8798.2015.1.4576 ◽

2015 ◽

Author(s):

В. Б Фурдела

Keyword(s):

Blood Pressure ◽

Metabolic Syndrome ◽

Abdominal Obesity ◽

Epidemiological Studies ◽

Overweight And Obesity ◽

Normal Blood ◽

Normal Blood Pressure ◽

Prevalence Of Obesity ◽

Prepubertal Boys ◽

Pubertal Boys

КЛІНІЧНІ ТА ФЕНОТИПІЧНІ ПАТЕРНИ У ШКОЛЯРІВ ІЗ НАДЛИШКОВОЮ МАСОЮ ТІЛА ТА ОЖИРІННЯМ - У статті наведено результати епідеміологічного дослідження 540 школярів двох середньоосвітніх шкіл м. Тернополя віком 9-17 років із метою встановлення частоти надлишкової маси тіла, ожиріння та метаболічного синдрому і простеження клінічних та фено- типічних особливостей цих патологічних станів серед дитячого населення. Отримані результати показали, що частота надлишкової маси тіла серед школярів Тернополя становить 11.1 %, а ожиріння - у 4,8 % (11,8 - в дівчат і 14,8 % - у хлопців), хлопці тричі частіше хворіють на ожиріння і в 1,4 раза з надлишковою масою тіла, ніж дівчата, а частота дефіциту маси тіла не залежить від статі. У пубертаті хлопці втричі частіше хворіють на ожирінням: 7,3 % хлопці та 2,3 % дівчата (F=0,523, р<0,05) і більш схильні до надлишкової маси (11,1 та 6,4 % відповідно). Абдомінальне ожиріння загалом серед дітей і підлітків зафіксовано у 4 % хлопців та вдвічі рідше (1,9 %) у дівчат. Поширеність абдомінального ожиріння (як маркера метаболічного синдрому) серед школярів з надлишковою масою становить 19,3 % серед обстежениххлопчиків і 18,5 % серед дівчат. Між показниками АТ та ІМТ існує пряма залежність, більш виражена у хлопців, ніж у дівчат. Кожен другий хлопець з ожирінням має лабільну АГ, а серед дівчаток з ожирінням у 50 % фіксується нормальний АТ, і лише кожна шоста має передгіпертензію. КЛИНИЧЕСКИЕ И ФЕНОТИПИЧЕСКИЕ ПАТТЕРНЫ У ПОДРОСТКОВ С ИЗБЫТОЧНЫМ ВЕСОМ ТЕЛА И ОЖИРЕНИЕМ - В статье приведены результаты эпидемиологического исследования 540 школьников двух среднеобразовательных школ г. Тернополя возрастом 9-17 лет с целью установления частоты избыточного веса тела, ожирения и метаболического синдрома и прослеживания клинических и фенотипических особенностей этих патологических состояний среди детского населения. Полученные результаты показали, что частота избыточного веса тела среди школьников г. Тернополя составляет 11,1 %, а ожирение - в 4,8 % (11,8 - у девочек и 14,8 % - у мальчиков), мальчики трижды чаще болеют ожирением и в 1,4 раза чаще избыточным весом тела, чем девочки, а частота дефицита веса тела не зависит от пола. В пубертате ребята втрое чаще болеют ожирением: 7,3 % юноши и 2,3 % девушки (F=0,523, р<0,05) и более склонны к избыточному весу (11,1 % и 6,4 % соответственно). Абдоминальное ожирение в целом среди детей и подростков зафиксировано в 4 % ребят и вдвое реже (1,9 %) у девушек. Распространенность абдоминального ожирения (как маркера метаболического синдрома) среди школьников с избыточным весом составляет 19,3 % среди обследованных мальчиков и 18,5 % среди девушек. Между показателями АД и ИМТ существует прямая зависимость более выражена у ребят, чем у девушек. Каждый второй парень с ожирением имеет лабильную АГ, а среди девушек с ожирением в 50 % фиксируется нормальное АД, и лишь каждая шестая имеет передгипер- тензию. CLINICALAND PHENOTYPIC PATTERNS IN SCHOOLCHILDREN WITH OVERWEIGHT AND OBESITY - In the article has presented the results ot epidemiological studies ot the trequency ot overweight, obesity and metabolic syndrome among 540 schoolchildren in Ternopil city 9-17 years old. The aim is to determine the incidence ot overweight, obesity, metabolic syndrome and hypertension among Ternopil schoolchildren and to trace clinical and phenotypic teatures otthese pathological conditions among children. The results showed that the incidence ot overweight among schoolchildren is 11.1 % and obesity - 4.8 % (11.8 % girls and 14.8 % boys). In prepubertal boys three times more often obesity develops and 1.4 times more often overweight develops than in girls, and frequency of underweight is independent of gender. In pubertal boys three times more often obesity develops: 7.3 % of boys and 2.3 % of girls (F = 0.523, p<0.05) and more often overweight (11.1 and 6.4 % respectively). Abdominal obesity in general among children and adolescents recorded in 4 % of boys and half less (1.9 %) in girls. The prevalence of abdominal obesity (as a marker of metabolic syndrome) among overweight school children is 19.3 % of the examined boys and 18.5 % of girls. Between BMI and blood pressure values a direct relationship is more pronounced in boys than in girls. Every second obese guy has labile hypertension and among obese girls in the 50 % recorded normal blood pressure, and only each sixth girl has high normal blood pressure. Ключові слова: поширеність ожиріння, надлишкова маса, метаболічний синдром, школярі. Ключевые слова: распространенность ожирения, избыточный вес, метаболический синдром, школьники. Key words: prevalence of obesity, overweight, metabolic syndrome, schoolchildren.

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BMI, waist to height ratio and waist circumference as a screening tool for hypertension in hospital out patients: a cross-sectional study

10.21203/rs.3.rs-66161/v1 ◽

2020 ◽

Author(s):

Rajan Shrestha ◽

Bijay Khatri ◽

Madan P. Upadhyay ◽

Janak R. Bhattarai ◽

Manish Kayastha ◽

...

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Waist Circumference ◽

Area Under The Curve ◽

Overweight And Obesity ◽

Anthropometric Measurements ◽

Height Ratio ◽

Cross Sectional ◽

High Waist Circumference ◽

Waist To Height Ratio

Abstract Background: Obesity has become a global epidemic with a rise in noncommunicable diseases. It is now becoming the problem of low- and middle-income countries such as Nepal. Conventional risk factors are present in a high proportion in the Nepalese population. As a routine surveillance or registry system is absent, the actual burden and trend of obesity and hypertension in Nepal are unknown. Hypertension and other cardiovascular diseases can be prevented by detecting risk factors such as obesity and high blood pressure. A simple anthropometric measurement could be used to determine the risk of hypertension. However, the best predictor of hypertension remains contentious and controversial. We aimed to determine the burden of obesity and hypertension and test the ability to determine hypertension through different anthropometric measurements in hospital outpatients in a low-income setting.Methods: This hospital-based cross-sectional descriptive study was conducted from June to December 2019 among 40-69 year outpatients in a tertiary eye and ENT hospital in a semi-urban area of Nepal among a randomly selected sample of 2,256 participants from 6,769 outpatients visited in Health Promotion and risked factor screening service. We performed a correlation analysis to determine the relationship between anthropometric measurements and blood pressure. The area under the receiver operating characteristic (ROC) curve of body mass index (BMI), waist to height ratio (WHtR) and waist circumference (WC) was calculated and compared.Results: The mean (SD) age of the participants was 51.75 (8.47) years. The overall prevalence of obesity and overweight by BMI was 16.09% and 42.20%, respectively. The overall prevalence of abdominal obesity by waist-to-height ratio was 32.76%, which is higher than obesity by BMI. High waist circumference was observed among 66.76% participants, whereas female participants had a very higher prevalence of high waist circumference (77.46%) and male participants (53.73%) (p<0.001). The prevalence of hypertension among the participants with BMI≥25 kg/m2, WHtR≥0.5 and WC≥ cutoff values was 45.97%, 42.52% and 45.28%, respectively. The overall prevalence of hypertension and prehypertension was 40.67% and 36.77%, respectively. Male participants had a slightly higher prevalence of hypertension (42.72%) than female participants (39.00%). The areas under the curve (AUCs) were significantly higher than 0.5 for BMI (0.570, 95% CI: 0.548-0.592), WC (0.585, 95% CI: 0.563-0.607) and WHtR (0.586, 95% CI: 0.564-0.608). In both genders, the area under the curve was significantly higher than 0.5 (P<0.01). In all age groups, the area under the curve was also significantly higher than 0.5.Conclusion: Waist circumference was both correlated as well as had higher predictive capacity amongst WHtR and BMI and may play a major role in the future diagnosis of HTN in Nepali adults. Regardless of the anthropometric metrics used to measure overweight and obesity, the hospital setting is an opportunity centre to screen for overweight, obesity and hypertension, which are major risk factors for NCDs.

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Abstract P377: Multicomponent Workplace Wellness Program Results in Weight Loss and Improved Cardiometabolic Indices

Circulation ◽

10.1161/circ.137.suppl_1.p377 ◽

2018 ◽

Vol 137 (suppl_1) ◽

Author(s):

Ryan R Bailey ◽

Ellen Fitzsimmons-Craft ◽

Holley Boeger ◽

Katie Keenoy ◽

Sara Hendrickson ◽

...

Keyword(s):

Blood Pressure ◽

Weight Loss ◽

Body Weight ◽

Waist Circumference ◽

Overweight And Obesity ◽

Workplace Wellness ◽

Wellness Program ◽

Percent Weight Loss ◽

Phone Calls ◽

Secondary Outcomes

Introduction: Workplace wellness programs offer opportunities for decreasing obesity in adults. The effectiveness of such programs varies and is influenced by key intervention components (e.g. duration, intensity, content). We developed a multicomponent workplace wellness program, MyWay to Health (MW2H), which was adapted from an evidence-based weight loss intervention with demonstrated efficacy and meets the 2013 Guideline for the Management of Overweight and Obesity in adults. The purpose of this one-group pretest-posttest study was to evaluate program acceptability and effectiveness of MW2H on primary and secondary outcomes. Hypotheses: We hypothesized that MW2H would result in 1) clinically meaningful weight loss of ≥5%, and 2) improvements in cardiometabolic indices. Methods: During weeks 1-26, participants met privately with an interventionist for up to 24 weekly, 40-minute sessions, receiving training in eating and physical activity behavior change, self-regulation, and socioenvironmental strategies. During weeks 27-52, participants received maintenance support through phone calls, email, or in-person visits. Our primary outcome was percent weight loss. Secondary outcomes included improvement in BMI, waist circumference, HbA1c, cholesterol, and blood pressure. Outcomes were compared at baseline and 26 weeks; body weight only was measured at 52 weeks. Wilcoxin Signed Rank Tests were used to examine outcomes. Results: Participants (N=154) were mostly female (85%), White (75%), had a median age of 50 (Interquartile Range (IQR): 17) years, a median baseline BMI of 34.7 (IQR: 8.8), a median household income of $70,000 (IQR: $50,000), and 54% had a college degree or higher. Median number of in-person sessions attended was 19 (IQR: 4.0). Percent weight loss at 26 weeks (median [IQR]: 7.5% [6.8%]) was clinically meaningful, with 71% of participants achieving ≥5% weight loss. Statistically significant improvements in BMI, waist circumference, HbA1c, HDL cholesterol, and systolic and diastolic blood pressure (p<0.001 for all) were observed. At week 52, body weight data were available for 106 (69%) participants. Median percent weight loss from baseline was 7.0% (IQR: 9.3%). Of participants who achieved ≥5% weight loss at week 26, 94% maintained this level of weight loss at week 52. Conclusions: The MW2H workplace wellness program was acceptable to participants, evidenced by high program attendance, and resulted in clinically meaningful and statistically significant improvements in body weight and cardiometabolic indices. A majority of participants achieved ≥5% weight loss by 26 weeks, and nearly all participants for whom data was available maintained this level of weight loss at week 52. Additional research is needed to optimize intervention components, identify factors that contribute to weight maintenance, and examine MW2H effectiveness in a more diverse population.

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Impact of Abdominal Obesity on Thyroid Auto-Antibody Positivity: Abdominal Obesity Can Enhance the Risk of Thyroid Autoimmunity in Men

International Journal of Endocrinology ◽

10.1155/2020/6816198 ◽

2020 ◽

Vol 2020 ◽

pp. 1-6

Author(s):

Jazyra Zynat ◽

Suli Li ◽

Yanrong Ma ◽

Li Han ◽

Fuhui Ma ◽

...

Keyword(s):

Waist Circumference ◽

Abdominal Obesity ◽

Thyroid Autoimmunity ◽

Large Population ◽

Overweight And Obesity ◽

Thyroid Peroxidase ◽

Hip Circumference ◽

Autoimmune Thyroid Diseases ◽

Autoimmune Thyroid ◽

Logistic Analysis

Background. The interrelation between obesity and autoimmune thyroid diseases is complex and has not been confirmed. The aim of the present study was to observe the relationship between thyroid autoimmunity and obesity, especially abdominal obesity, in a large population. Methods. A total of 2253 residents who had lived in Xinjiang for more than 3 years were enrolled. Serum thyroid hormone concentration, thyroid autoantibodies, lipid parameters, Weight, height, and waist and hip circumference were measured. Results. The prevalence of thyroid peroxidase antibody (TPOAb) and/or thyroglobulin antibody (TgAb) positive was 32.1% (21.2% in men and 37% in women, P<0.01). Compared with women, men had significantly higher TG levels, waist circumference, and hip circumference levels (P<0.01), while women showed higher TSH, TPOAb, and TgAb levels (P<0.01). The prevalence of overweight and obesity was 71.1% in men and 63.5% in women. Men had a higher prevalence of abdominal obesity than women (56.6% in men and 47.6% in women, P<0.01). TPOAb correlates positively with waist circumference (r = 0.100, P<0.05) in men. Binary logistic analysis showed that TPOAb positivity had increased risks of abdominal obesity in men, and the OR was 1.1044 (95% CI 1.035, 1.151, P<0.05). Conclusion. Our results indicate that men had higher lipid levels, thicker waist circumference, and higher prevalence of overweight, obesity, and abdominal obesity. Abdominal obesity is a risk factor for TPOAb positivity in men, suggesting that abdominal obesity can enhance the risk of thyroid autoimmunity in men.

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