General and central obesity operate differently as predictors of falls requiring medical care in older women: a population-based cohort study in Spain

Abstract Objectives to examine the association of general and abdominal obesity with falls, falls requiring medical care and falls with fractures in older women. Design a population-based prospective cohort of 1,185 women aged ≥60 in Spain, followed up from 2008 to 2010 through 2012. Measures weight, height and waist circumference were measured at baseline using standardised techniques. Participants were classified according to body mass index as normal weight (<25), overweight (25–29.9) and general obesity (≥30). Abdominal obesity was defined as waist circumference >88 cm. In 2012, participants reported the falls experienced in the previous year. Logistic regression models were mutually adjusted for general and abdominal obesity and for main confounders. Results in this cohort of older women, a total of 336 women experienced falls, 168 of them had falls requiring medical care and 64 falls with fractures. For falls, no association was found with general obesity nor abdominal obesity. However, compared with normal weight, overweight women had a decreased risk for falls requiring medical care [odds ratio (OR) 0.57; 95% confidence interval (CI) 0.34–0.94] and for falls with fractures (OR 0.27; 95% CI 0.12–0.63). The corresponding values for general obesity were 0.44 (0.24–0.81) and 0.30 (0.11–0.82). Abdominal obesity was positively associated with falls requiring medical care (OR 1.82; 95% CI 1.12–2.94) and falls with fractures (OR 2.75; 95% CI 1.18–6.44). Conclusions in older women, general obesity may protect from falls requiring medical care and falls with fractures. On the contrary, abdominal obesity increased the risk of suffering from types of falls.

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1402Thyroid stimulating hormone (TSH) is associated with general and abdominal obesity in girls during puberty

International Journal of Epidemiology ◽

10.1093/ije/dyab168.697 ◽

2021 ◽

Vol 50 (Supplement_1) ◽

Author(s):

Yingying Wang

Keyword(s):

Logistic Regression ◽

Abdominal Obesity ◽

Regression Models ◽

Population Based ◽

Thyroid Stimulating Hormone ◽

General Obesity ◽

Logistic Regression Models ◽

The Impact ◽

Serum Tsh ◽

Stimulating Hormone

Abstract Background Childhood is an important public health issue. Although both thyroid hormone and menarche are known to play a role in body metabolism and energy expenditure, no population-based study has been conducted to investigate the impact of TSH on adipogenesis among population-based girls around puberty. Methods A multi-stage cluster sampling method was used to select one junior middle school from each of 4 study areas: Minhang District in Shanghai, Haimen City in Jiangsu Province, Yuhuan City and Deqing County in Zhejiang Province. A total of 474 girls aged 11 to 14 years from 4 schools were enrolled. Information on demographic factors and puberty stage were collected, and anthropometric measurements and thyroid hormones were determined. Multivariate logistic regression models were used to assess the associations of Thyroid stimulating hormone (TSH) with the risk of obesity measured by body mess index (BMI) and waist circumference (WC). Results Of the 474 girls, the prevalences of BMI-based general obesity and WC-based abdominal obesity were 19.8% (94/474) and 21.7% (103/474), respectively. Compared with normal weight girls, the mean serum TSH concentration was significantly higher in BMI-based general overweight or obese girls (P = 0.037), but not in WC-based central overweight or obese girls (P = 0.173). In the multiple logistic regression models, for girls with highest tertile of serum TSH concentration relative to those in the lowest tertile, the odds ratios were 2.58 (95% CI 1.32 to 5.04) and 2.50 (95% CI 1.30 to 4.81) for overweight or obesity based on BMI and WC after adjustment for puberty stage and other covariates. Conclusions Serum TSH concentration was positively associated with both general and abdominal obesity in school-age girls and the association was independent of puberty. Key messages thyroid stimulating hormone; general obesity; central obesity; school-aged girls; puberty

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Correlates of Adverse Outcomes in Abdominally Obese Individuals: Findings from the Five-Year Followup of the Population-Based Study of Health in Pomerania

Journal of Obesity ◽

10.1155/2013/762012 ◽

2013 ◽

Vol 2013 ◽

pp. 1-7 ◽

Cited By ~ 3

Author(s):

Nele Friedrich ◽

Harald J. Schneider ◽

Ulrich John ◽

Marcus Dörr ◽

Sebastian E. Baumeister ◽

...

Keyword(s):

Abdominal Obesity ◽

Regression Models ◽

Kidney Diseases ◽

Premature Death ◽

Population Based ◽

Serum Glucose ◽

Adverse Outcomes ◽

Population Based Study ◽

Logistic Regression Models ◽

Increased Risk

Background. Abdominal obesity is a major risk factor of cardiovascular disease (CVD), type 2 diabetes (T2DM), and premature death. However, it has not been resolved which factors predispose for the development of these adverse obesity-related outcomes in otherwise healthy individuals with abdominal obesity.Methods. We studied 1,506 abdominal obese individuals (waist-to-height ratio (WHtR) ≥ 0.5) free of CVD or T2DM from the population-based Study of Health in Pomerania and assessed the incidence of CVD or T2DM after a five-year followup. Logistic regression models were adjusted for major cardiovascular risk factors and liver, kidney diseases, and sociodemographic status.Results. During follow-up time, we observed 114 and 136 new T2DM and CVD cases, respectively. Regression models identified age, waist circumference, serum glucose, and liver disease as predictors of T2DM. Regarding CVD, only age, unemployment, and a divorced or widowed marital status were significantly associated with incident CVD. In this subgroup of obese individuals blood pressure, serum glucose, or lipids did not influence incidence of T2DM or CVD.Conclusion. We identified various factors associated with an increased risk of incident T2DM and CVD among abdominally obese individuals. These findings may improve the detection of high-risk individuals and help to advance prevention strategies in abdominal obesity.

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Assessment of Obesity using Anthropometric Markers among University Students

Current Research in Nutrition and Food Science Journal ◽

10.12944/crnfsj.9.1.21 ◽

2021 ◽

Vol 9 (1) ◽

pp. 211-221

Author(s):

Astha Astha ◽

Bindu Krishnan ◽

Anup Kharde

Keyword(s):

Young Adults ◽

Waist Circumference ◽

Abdominal Obesity ◽

Central Obesity ◽

Normal Weight ◽

Asia Pacific ◽

General Obesity ◽

Height Ratio ◽

Anthropometric Measures ◽

High Positive Correlation

Over the past few decades there has been an increase in the central or abdominal obesity. Endothelial dysfunction, insulin resistance with metabolic syndrome and a higher cardiometabolic risk are directly linked to abdominal obesity. A better understanding of the epidemiology of obesity would provide insights to its mitigation. This cross sectional study was designed to identify Central obesity, General obesity and Normal Weight central obesity among young adults using the following surrogate markers Waist circumference (WC), Waist hip ratio (WHR), Waist height ratio (WtHR) and BMI. After due informed written consent, 300 young adults with equal representation of both sexes (150 each) studying MBBS, Dentistry and Physiotherapy stream in a private university were selected. Various anthropometric measures like weight, hip circumference and waist circumference and height were measured according to WHO STEPS instrument. BMI based on Asia- Pacific cut -off values was used to define general obesity. Central obesity was defined by a Waist Circumference of  80 cm in females and  90 cm in male’s .For waist to height ratio a value of  0.5 in both genders was used. For waist to hip ratio the cut off value used was 0.85 in females and 0.90 in males. An individual with normal weight according to BMI but having central obesity fits into Normal Weight Central obesity category. Average age of the participants was 20.6 1.31 years. General Obesity was more among males with 46% prevalence as compared to 25.33%among females. In contrast, the prevalence of central obesity was more among females. The prevalence of Normal weight central obesity was more among females, varying from 4% to 17% using different types of anthropometric measures for central obesity. A high positive correlation was observed between BMI with WC, WtHR and WHR. (p=0.0001) Current practice of taking only BMI into consideration for defining obesity in our country needs serious re-evaluation considering the increasing prevalence of abdominal obesity and its long term impact.

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Thyroid stimulating hormone (TSH) is associated with general and abdominal obesity in girls during puberty

10.21203/rs.2.17011/v1 ◽

2019 ◽

Author(s):

Yingying Wang ◽

Xiaolian Dong ◽

Chaowei Fu ◽

Meifang Su ◽

Feng Jiang ◽

...

Keyword(s):

Logistic Regression ◽

Abdominal Obesity ◽

Regression Models ◽

Thyroid Stimulating Hormone ◽

Normal Weight ◽

Public Health Issue ◽

Cluster Sampling ◽

Logistic Regression Models ◽

Serum Tsh ◽

Stimulating Hormone

Abstract Background: Childhood obesity is an important public health issue. Although both thyroid hormone and menarche are known to play a role in body metabolism and energy expenditure, evidence for these associations in girls around puberty was limited. This study was aimed to investigate the association of TSH with general and abdominal obesity in girls during puberty. Methods: A multi-stage cluster sampling method was used to select one junior middle school from each of 4 study areas: Minhang District in Shanghai, Haimen City in Jiangsu Province, Yuhuan City and Deqing County in Zhejiang Province. A total of 474 girls aged 11 to 14 years from 4 schools were enrolled. Information on demographic factors and puberty stage were collected, and anthropometric measurements and thyroid hormones were determined. Multivariate logistic regression models were used to assess the associations of Thyroid stimulating hormone (TSH) with the risk of obesity measured by body mess index (BMI) and waist circumference (WC). Results: Of the 474 girls, the prevalences of BMI-based general obesity and WC-based abdominal obesity were 19.8% (94/474) and 21.7% (103/474), respectively. Compared with normal weight girls, the mean serum TSH concentration was significantly higher in BMI-based general overweight or obese girls (P=0.037), but not in WC-based central overweight or obese girls (P=0.173). In the multiple logistic regression models, for girls with highest tertile of serum TSH concentration relative to those in the lowest tertile, the odds ratios were 2.63 (95% CI 1.34 to 5.14) and 2.53(95% CI 1.31 to 4.88) for overweight or obesity based on BMI and WC after adjustment for puberty stage and other covariates. Conclusions: Serum TSH concentration was positively associated with both general and abdominal obesity in school-age girls and the association was independent of puberty.

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Incidence of severe knee and hip osteoarthritis in relation to different measures of body mass: a population-based prospective cohort study

Annals of the Rheumatic Diseases ◽

10.1136/ard.2008.089748 ◽

2008 ◽

Vol 68 (4) ◽

pp. 490-496 ◽

Cited By ~ 201

Author(s):

L S Lohmander ◽

M Gerhardsson de Verdier ◽

J Rollof ◽

P M Nilsson ◽

G Engström

Keyword(s):

Cohort Study ◽

Waist Circumference ◽

Knee Osteoarthritis ◽

Body Mass ◽

Hip Osteoarthritis ◽

Population Based ◽

Normal Weight ◽

Men And Women ◽

Relative Risks ◽

Percentage Of Body Fat

Objective:To determine in a prospective population-based cohort study relationships between different measures of body mass and the incidence of severe knee and hip osteoarthritis defined as arthroplasty of knee or hip due to osteoarthritis.Materials and methods:Body mass index (BMI), waist circumference, waist–hip ratio (WHR), weight and percentage of body fat (BF%) were measured at baseline in 11 026 men and 16 934 women from the general population. The incidence of osteoarthritis over 11 years was monitored by linkage with the Swedish hospital discharge register.Results:471 individuals had knee osteoarthritis and 551 had hip osteoarthritis. After adjustment for age, sex, smoking and physical activity, the relative risks (RR) of knee osteoarthritis (fourth vs first quartile) were 8.1 (95% CI 5.3 to 12.4) for BMI, 6.7 (4.5 to 9.9) for waist circumference, 6.5 (4.6 to 9.43) for weight, 3.6 (2.6 to 5.0) for BF% and 2.2 (1.7 to 3.0) for WHR. Corresponding RR for hip osteoarthritis were 2.6 (2.0 to 3.4) for BMI, 3.0 (2.3 to 4.0) for weight, 2.5 (1.9 to 3.3) for waist, 1.3 (0.99 to 1.6) for WHR and 1.5 (1.2 to 2.0) for BF%.Conclusion:All measures of overweight were associated with the incidence of knee osteoarthritis, with the strongest relative risk gradient observed for BMI. The incidence of hip osteoarthritis showed smaller but significant differences between normal weight and obesity. Our results support a major link between overweight and biomechanics in increasing the risk of knee and hip osteoarthritis in men and women.

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Beverage intake and obesity in early childhood: evidence form primary health care clients in Northwest Argentina

Journal of Developmental Origins of Health and Disease ◽

10.1017/s204017441500793x ◽

2015 ◽

Vol 7 (3) ◽

pp. 244-252 ◽

Cited By ~ 1

Author(s):

E. Alderete ◽

I. Bejarano ◽

A. Rodríguez

Keyword(s):

Public Health ◽

Nutritional Status ◽

Regression Models ◽

Task Force ◽

Normal Weight ◽

The Body ◽

Logistic Regression Models ◽

Dietary Recall ◽

Northwest Argentina ◽

Artificial Fruit

Sugar sweetened beverages (SSB) are thought to play an important role in weight gain. We examined the relationship between the intake of caloric and noncaloric beverages (SSB and water) and the nutritional status of children. In 2014, we randomly selected 16 public health clinics in four cities of Northwest Argentina and conducted a survey among mothers of children 0–6 years of age. Children’s beverage intake was ascertained by 24-h dietary recall provided by the mothers. Children’s weight and height measures were obtained from clinic’s registries. We calculated the body mass index using the International Obesity Task Force standards. The analysis included 562 children 25 months to 6 years of age with normal or above normal nutritional status. Children’s beverage consumption was as follows, water 81.8%, carbonated soft drinks (CSD) 49.7%, coffee/tea/cocoa 44.0%, artificial fruit drinks 35.6%, flavored water 17.9%, natural fruit juice 14.5%. In multivariate logistic regression models the likelihood of being obese v. being overweight or having normal weight doubled with an intake of one to five glasses of CSD (OR=2.2) and increased by more than three-fold with an intake of more than five glasses (OR=3.5). Drinking more than five glasses of water decreased the likelihood of being obese by less than half (OR=0.3). The percentage of children drinking more than five glasses of other beverages was low (3.3–0.9%) and regression models did not yield significant results. The study contributed evidence for reducing children’s CSD intake and for promoting water consumption, together with the implementation of comprehensive regulatory public health policies.

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Women’s Autonomy and Support for Wife Beating: Findings From a Population-Based Survey in Jordan

Violence and Victims ◽

10.1891/0886-6708.25.3.409 ◽

2010 ◽

Vol 25 (3) ◽

pp. 409-419 ◽

Cited By ~ 25

Author(s):

Natalia Linos ◽

Marwan Khawaja ◽

Mohannad Al-Nsour

Keyword(s):

Regression Models ◽

Binary Logistic Regression ◽

Population Based ◽

Married Women ◽

Wife Beating ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Logistic Regression Models ◽

Hypothetical Scenario ◽

Population Based Survey

The aim of this study is to examine attitudes among married women toward wife beating and to investigate the hypothesis that female individual empowerment is associated with such attitudes within a broader context of societal patriarchy in Jordan. The study uses data from a cross-sectional survey of a representative sample of married women (n = 5,390) conducted in 2002. Associations between acceptance of wife beating and several women’s empowerment variables, including decision-making power, as well as other risk factors were assessed, using odds ratios from binary logistic regression models. The key finding is that the vast majority (87.5%) of Jordanian women believe that wife beating is justified in at least one hypothetical scenario, and justification is negatively associated with empowerment variables and some demographic, geographic, and socioeconomic factors.

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Association between Eating Away from Home and Hyperuricemia: A Population-Based Nationwide Cross-Sectional Study in China

BioMed Research International ◽

10.1155/2019/2792681 ◽

2019 ◽

Vol 2019 ◽

pp. 1-7 ◽

Cited By ~ 1

Author(s):

Zifeng Liu ◽

Xiaoting Su ◽

Mianli Xiao ◽

Peien Zhou ◽

Jianwei Guo ◽

...

Keyword(s):

Regression Models ◽

Population Based ◽

Cross Sectional Study ◽

Noncommunicable Diseases ◽

Sectional Study ◽

Nutrition Survey ◽

Cross Sectional ◽

Logistic Regression Models ◽

Health And Nutrition ◽

Home Food

Hyperuricemia (HU) is a risk factor for different kinds of chronic noncommunicable diseases, and eating away from home (EAFH) may play an important role in their development, which has been ignored greatly so far. This study aimed to investigate the association between EAFH and HU in different models. A cross-sectional study involving 8,322 participants of the China Health and Nutrition Survey (CHNS) was conducted. Logistic regression models were used to analyze the data. We found that participants who consumed more away-from-home food had a higher risk for HU, and the adjusted odds ratio (aOR) and 95% confidence interval (CI) (for each increment in grades of EAFH) were 1.11 (1.02, 1.20) in a multiadjusted model (adjusted for age, gender, province, net individual income, body mass index, smoking, leisure-time physical activities, energy intake, and sleep duration). As for stratified analyses, the aOR (95% CI) of EAFH was 1.12 (1.01, 1.24) for men and 1.06 (0.92, 1.21) for women. Similar results can be found in the middle-aged and obese population, with aOR (95% CI) of EAFH as 1.17 (1.05, 1.30) and 1.15 (1.03, 1.29), respectively. In conclusion, EAFH is positively associated with the prevalence of HU.

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Regional Variations in Trends for Multiple Births: A Population-Based Evaluation in France, 1972–2003

Twin Research and Human Genetics ◽

10.1375/twin.10.2.406 ◽

2007 ◽

Vol 10 (2) ◽

pp. 406-415 ◽

Cited By ~ 7

Author(s):

Babak Khoshnood ◽

Béatrice Blondel

Keyword(s):

Logistic Regression ◽

Regression Models ◽

Population Based ◽

Multiple Births ◽

Same Sex ◽

Regional Variations ◽

Logistic Regression Models ◽

Hierarchical Logistic Regression ◽

Country Level ◽

Infertility Treatments

AbstractThe aim of the study was to assess, using population-based data, trends and regional variations in multiple births during the period of increasing use and changes in practice patterns for infertility treatments. National data for 24,554,977 births (live births and stillbirths) were used, including 569,423 twins during the period 1972 to 2003, and 14,599 triplets for 1984 to 2003. Statistical analyses included age-adjusted hierarchical logistic regression models for twin births and separate analyses for triple, same-sex, and different-sex twin births. Due to confidentiality considerations, the only variable available for adjustment was maternal age. Regionallevel variations were estimated using median odds ratios based on random-intercept hierarchical logistic regression models. Overall, twin births increased from 18.1 per 1000 births (95% confidence interval [CI] 17.9–18.2) in 1972 to 1975 to 29.9 per 1000 (95% CI 29.7–30.1) in 2000 to 2003. Twin births increased progressively across all regions, whereas triple births reached a peak in the early 1990s and decreased thereafter. Trends for both twin and triple births varied significantly across regions. Both trends and regional variations were greater for different-sex as compared with same-sex twin births. Regional variations in the proportion of multiple births increased in the case of twin births and decreased for triple births. Differences in multiple births at the regional level in France were comparable to country-level differences observed across several western and northern European countries. Regional differences in multiple births need to be monitored and used to inform policies aimed at regulating the use of infertility treatments.

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A Simple Clinical Tool for Stratifying Risk of Clinically Significant CKD after Nephrectomy: Development and Multinational Validation

Journal of the American Society of Nephrology ◽

10.1681/asn.2019121328 ◽

2020 ◽

Vol 31 (5) ◽

pp. 1107-1117 ◽

Cited By ~ 1

Author(s):

Robert J. Ellis ◽

Sharon J. Del Vecchio ◽

Kevin M.J. Gallagher ◽

Danielle N. Aliano ◽

Neil Barber ◽

...

Keyword(s):

High Risk ◽

Kidney Cancer ◽

Regression Models ◽

Population Based ◽

Risk Category ◽

Shared Decision ◽

Clinical Tool ◽

Kidney Tumors ◽

Logistic Regression Models ◽

Clinically Significant

BackgroundClinically significant CKD following surgery for kidney cancer is associated with increased morbidity and mortality, but identifying patients at increased CKD risk remains difficult. Simple methods to stratify risk of clinically significant CKD after nephrectomy are needed.MethodsTo develop a tool for stratifying patients’ risk of CKD arising after surgery for kidney cancer, we tested models in a population-based cohort of 699 patients with kidney cancer in Queensland, Australia (2012–2013). We validated these models in a population-based cohort of 423 patients from Victoria, Australia, and in patient cohorts from single centers in Queensland, Scotland, and England. Eligible patients had two functioning kidneys and a preoperative eGFR ≥60 ml/min per 1.73 m2. The main outcome was incident eGFR <45 ml/min per 1.73 m2 at 12 months postnephrectomy. We used prespecified predictors—age ≥65 years old, diabetes mellitus, preoperative eGFR, and nephrectomy type (partial/radical)—to fit logistic regression models and grouped patients according to degree of risk of clinically significant CKD (negligible, low, moderate, or high risk).ResultsAbsolute risks of stage 3b or higher CKD were <2%, 3% to 14%, 21% to 26%, and 46% to 69% across the four strata of negligible, low, moderate, and high risk, respectively. The negative predictive value of the negligible risk category was 98.9% for clinically significant CKD. The c statistic for this score ranged from 0.84 to 0.88 across derivation and validation cohorts.ConclusionsOur simple scoring system can reproducibly stratify postnephrectomy CKD risk on the basis of readily available parameters. This clinical tool’s quantitative assessment of CKD risk may be weighed against other considerations when planning management of kidney tumors and help inform shared decision making between clinicians and patients.

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