scholarly journals EVALUATION OF ROD BREAKAGE AFTER THREE-COLUMN OSTEOTOMY

2020 ◽  
Vol 19 (1) ◽  
pp. 44-47
Author(s):  
FERNANDO BRENO DE OLIVEIRA RIBEIRO ◽  
ALDERICO GIRÃO CAMPOS DE BARROS ◽  
JUAN DANIEL PAZOS AQUINO ◽  
RODRIGO JOSÉ FERNANDES DA COSTA ◽  
LUIS EDUARDO CARELLI TEIXEIRA DA SILVA
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Statistical Significance ◽  
Pedicle Subtraction Osteotomy ◽  
Categorical Variables ◽  
Level Of Evidence ◽  
Vertebral Column Resection ◽  
Rod Breakage ◽  
The Mean

ABSTRACT Objective To identify the incidence and possible risk factors associated with rod breakage in patients who underwent vertebral column resection (VCR) or pedicle subtraction osteotomy (PSO) to treat complex deformities of the spine. Methods Retrospective analysis of a series of 32 patients operated from 2014 to 2018 in a single center. The patients were analyzed for demographic (sex, age), biometric (BMI), radiographical (pre- and postoperative angular variations), and surgical (arthrodesed and osteotomized levels) characteristics. Descriptive analyses were performed for the numerical variables (mean, standard deviation, maximum, median, and minimum) and frequency analysis was performed for the categorical variables. Logistic regression analysis was performed for the dependent variable “rod breakage”, using a stepwise technique to select the variables for the best model, assuming statistical significance of 0.05. Results Of the 32 patients selected, rod breakage occurred in 34.4%. Mean age was 36.6 years (± 19.8), ranging from 10 to 74 years, and the mean BMI was 25.1 (±6.0). Most patients were subjected to VCR (75.0%), were males (56.2%) and did not smoke (90.6%). Logistic regression analysis showed that “arthrodesed levels” were was positively associated with rod breakage (OR 1.72; CI95%: 1.13-3.10; p<0.05). The other factors were not associated with breakage. Conclusion Rod breakage is a frequent complication after three-column osteotomy, especially in long constructions. Level of evidence III; Retrospective Study.

A comparison of African Buffalo, N'Dama and Boran cattle as reservoirs of Trypanosoma vivax for different Glossina species

Parasitology ◽  
1993 ◽  
Vol 106 (3) ◽  
pp. 277-282 ◽  
Author(s):  
S. K. Moloo ◽  
G. Gettinby ◽  
R. O. Olubayo ◽  
J. M. Kabata ◽  
I. O. Okumu
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
African Buffalo ◽  
Trypanosoma Vivax ◽  
Infection Rates ◽  
Glossina Morsitans Centralis ◽  
The Mean ◽  
N’Dama Cattle ◽  
Buffalo Cow

SUMMARYTeneral Glossina morsitans centralis were fed on the flanks of African buffalo, N'Dama or Boran cattle infected with Trypanosoma vivax IL 2337. The infected tsetse were maintained on goats and on day 25 after the infected feed, the surviving tsetse were dissected to determine the infection rates. The mean mature infection rates (% ± S.E.) in the tsetse fed on buffalo, N'Dama and Boran cattle were 34·3 ± 9·9, 33·7 ± 13·4 and 58·9 ± 7·1, respectively. Logistic regression analysis indicated that infection rates in the labrum and hypopharynx of the tsetse were significantly lower when fed on the infected buffalo or N'Dama than Boran cattle. Similarly, the risk of infection was significantly lower in male than female tsetse. When teneral G. m. centralis, G. pallidipes, G. p. gambiensis, G. brevipalpis and G. longipennis were fed simultaneously on either the buffalo cow, the N'Dama bull or the Boran steer infected with T. vivax IL 2337, the mature infection rates were higher in the two morsitans group than the two fusca group tsetse, whilst G. p. gambiensis was relatively refractory to the infection, irrespective of the host species on which they fed. Logistic regression analysis indicated that the infection rates in the labrum and hypopharynx were significantly different amongst the five tsetse species for each of the three infected host animals. Nevertheless, the trypanotolerant African buffalo and N'Dama cattle may serve as reservoirs of T. vivax infection as can trypanosusceptible Boran cattle.

scholarly journals Coagulopathy and damage control resuscitation during transfer due to massive hemorrhage –a single-center retrospective study–

2020 ◽  
Author(s):  
Hiroyuki Takahashi ◽  
Tomohisa Shoko ◽  
Mitsuaki Kojima ◽  
Satoshi Nara
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Damage Control ◽  
Massive Hemorrhage ◽  
Categorical Variables ◽  
Stepwise Logistic Regression ◽  
Damage Control Resuscitation ◽  
Single Center ◽  
Factors Associated

Abstract Background: To assess medical procedures, particularly damage control resuscitation, at the time of transfer between hospitals for the purpose of treating massive hemorrhage.Methods: This study used a single-center retrospective observational design, enrolling patients referred to Teine Keijinkai Hospital from another hospital between April 2012 and March 2019 for the treatment of massive hemorrhage. We excluded patients who entered cardiac arrest before arriving at our center. Qualitative or categorical variables were compared using the χ2 or Fisher’s exact test, as appropriate. Quantitative continuous variables were compared using Mann-Whitney nonparametric tests, as appropriate. Risk factors associated with coagulopathy from univariate analyses (fibrinogen level £150 mg/dl; prothrombin time-international normalized ratio ³1.5) were entered into stepwise logistic regression analysis. Significance was defined for values of p < 0.05.Results: Multiple logistic regression analysis revealed trauma (odds ratio (OR) 4.800; 95% confidence interval (CI) 2.016–11.433; p < 0.001) and volume of crystalloid solution (OR 1.001; 95%CI 1.000–1.001; p = 0.008) as independent factors associated with coagulopathy. Patients with coagulopathy showed higher 24-h mortality rates (10.9%) than patients without coagulopathy (1.2%; p = 0.021), and cause of death was hemorrhagic shock for all cases of death within 24 h.Conclusion: In our area, withholding intravenous fluid to achieve permissive hypotension, early administration of fresh frozen plasma, and use of fibrinogen concentrate may improve the prognosis of patients with massive hemorrhage undergoing transfer between hospitals.Trial registration: UMIN, UMIN000041201. Registered 24 July 2020 – Retrospectively registered, https://upload.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000047048

scholarly journals Abdominal obesity as a risk factor for stroke in Abuja, Nigeria

2021 ◽  
Vol 9 (9) ◽  
pp. 2573
Author(s):  
Gerald A. Onwuegbuzie ◽  
Peter Alabi ◽  
Fatima Abdulai
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Risk Factor ◽  
Abdominal Obesity ◽  
Logistic Regression Analysis ◽  
Statistical Significance ◽  
Lifestyle Changes ◽  
Health Concern ◽  
Increased Risk

Background: Obesity in Africa has remained a public health concern, which is been fueled by urbanization and its attendant lifestyle changes which includes less energy demanding jobs, sedentary lifestyle and adopting detrimental western eating habits. There are well established risk factors for stroke, however the association of obesity with that of stroke is less clear.Methods: This study was designed to determine whether abdominal obesity is independently associated with an increased risk of ischaemic stroke. It is a case control study of 113 patients in which structured questionnaire was administered to consecutive patients admitted into the medical wards. The controls were matched for age and sex from a database with participants of the population-based cohort study. Statistical analysis of data was performed using SAS software (SAS Institute) 9.4.Results: In the study 85% of the patients had hypertension, 50.5% had hypercholesterolemia and 33.6% had diabetes. The BMI was normal for most of the cases (23.3% vs. 76.7% p<0.0001) while the WHR was increased for most of the cases (70.9% vs. 29.1% p<0.0001). The statistical significance shows that WHR was more sensitive in assessing obesity than BMI. The logistic regression analysis, in model 1 unadjusted and model 2 adjusted for sex and age, BMI showed a positive association with risk of stroke (OR 1.10; 95% CI, 1.04-1.17; p=0.002) this association lost its significance in model 3 after adjusting for diabetes, hypertension and hypercholesterolemia (OR 1.04; 95% CI, 0.96-1.13; p=0.3751). The results of logistic regression analysis for WHR for model 1, model 2 and model 3 did not show any significance before and after adjustment.Conclusions: Abdominal obesity may increase the risk of ischemic stroke through conventional vascular risk factors, but not as an independent risk factor.

scholarly journals P232 In suspected small bowel Crohn’s disease: Clinical impact of using capsule endoscopy to make decisions

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S258-S259
Author(s):  
R A Gonzalez ◽  
E J Gómez ◽  
L Pereyra ◽  
J M Mella ◽  
G N Panigadi ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Logistic Regression Analysis ◽  
Capsule Endoscopy ◽  
Clinical Impact ◽  
Therapeutic Decisions ◽  
The Mean

Abstract Background Capsule endoscopy (CE) can detect small bowel (SB) lesions compatible of Crohn’s disease (CD) in patients with suggestive symptoms but with inconclusive results for the diagnostic workup. However, the clinical impact of CE in helping physicians to make decisions about patients with suspected CD is not currently well established. The aim of the study was to investigate the clinical impact of CE to confirm diagnosis of CD and also to evaluate whether the results of CE modify therapeutic decisions. Methods We conducted a single-centre retrospective cohort study. All consecutive adult’s patients submitted to CE for clinical suspected of CD, on period November 2012 to November 2018, were included. Data on demography, previous research, medications for IBD, CE procedures and follow-up were analysed. Multivariate logistic regression analysis was carried out to identify predictors of CD. Results A total of 329 CE protocols in adult’s patients were performed over the study period. Ninety were in IBD patients and were included in the analysis 63 CEs submitted for suspected of CD: Clinical suspected CD 54(86%) and colitis unclassified 9 (14%). The mean age was 41 years (range 17–77 years) and 54% were males. The CE reached the caecum in 58 cases (92%) and retention was observed in 5 (8%) with only one patient (1.6%) requiring surgical removal. Overall, 28 of 63 patients (44%) had CE findings consistent with the diagnosis of CD. The lesions identified by CE included ulcers 24 (86%), erythema and villous oedema 17(61%), aphthas and mucosal erosions 5 (18%), stenosis 2 (7%) and were distributed mainly in the distal part of the SB (third tertile) in 23 (82%), but in 14 (50%) cases the proximal SB (first and second tertiles) was also affected. The mean Lewis Score (LS) was 903 (112–4356). Significant inflammatory activity (LS ≥ 135) was detected in 17 (27%) and was moderate or severe (LS &gt; 790) in 7 (11%). CE visualise normal SB mucosa in 34 (54%) of patient’s, which rules out CD. Therapeutic started in 23 (36%) of patients, initiating a new IBD medication in most cases in the 3 months after the CE. On logistic regression analysis, male (p = 0.02) and findings in ileocolonoscopy (p = 0.004) were independents predictors of CD. Conclusion In our cohort, CE in suspected CD confirm diagnosis in 44% of cases. Male gender and findings in ileocolonoscopy appear to be independents predictors of CD. CE is a useful tool in suspected CD, since it adds relevant information for diagnosis and had a great impact on therapeutic decisions.

Low Tibial Valgization Osteotomy for More Severe Varus Ankle Arthritis

2020 ◽  
Vol 41 (9) ◽  
pp. 1122-1132
Author(s):  
Jun Young Choi ◽  
Kun Woo Kim ◽  
Jin Soo Suh
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Binary Logistic Regression ◽  
Binary Logistic Regression Analysis ◽  
Ankle Arthritis ◽  
Level Of Evidence ◽  
Opening Wedge ◽  
Hindfoot Alignment ◽  
Factors Influencing

Background: Low tibial valgization osteotomy with medial opening wedge (LTO) is generally indicated for ankle arthritis with a small talar tilt (TT). We addressed the following research questions: the efficacy of LTO for more significant varus ankle arthritis, the effect of additional inframalleolar correction followed by LTO, and the preoperative or operation-related factors influencing postoperative TT decrease. Methods: We retrospectively reviewed the radiographic and clinical findings of 31 patients with more significant varus ankle arthritis (≥8 degrees) who underwent LTO or LTO plus inframalleolar correction. We grouped the included patients according to combination with inframalleolar correction and postoperative decreased TT. Furthermore, a binary logistic regression analysis was performed to determine the factors influencing postoperative TT decrease. Results: Even though the mean TT was unchanged postoperatively (from 12.1 to 9.9 degrees, P = .052), clinical parameters were significantly increased. In the group with concomitant inframalleolar correction, we found that TT was more corrected (3.9 vs 1.8 degrees, P = .023) with a greater lateralization of the talar center and a greater correction of the hindfoot alignment to valgus. The results of the binary logistic regression analysis showed a significant relationship between postoperative decreased TT and preoperative talar center migration ( P = .016), hindfoot alignment angle ( P = .033), hindfoot moment arm ( P = .041), and hindfoot alignment ratio ( P = .016). Conclusion: LTO in more significant varus ankle arthritis could result in clinical improvement, although TT was not significantly changed. We recommend adding inframalleolar correction after LTO for the patients with more significant varus ankle arthritis. Level of Evidence: Level III, comparative series.

A Proposed Methodology for the Assessment of Glaucoma Awareness in Greece: Introduction of the EIT-8G Scale

2011 ◽  
Vol 22 (1) ◽  
pp. 95-103 ◽  
Author(s):  
Georgios Labiris ◽  
Andreas Katsanos ◽  
Michael Fanariotis ◽  
Anna Koutsogianni ◽  
Athanassios Giarmoukakis ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Family History ◽  
Logistic Regression Analysis ◽  
Rasch Analysis ◽  
Statistical Significance ◽  
Multivariate Logistic Regression Analysis ◽  
Control Group ◽  
Valid Instrument ◽  
The Impact

Purpose To develop a reliable and practical questionnaire for glaucoma awareness and evaluate the impact of potential determinants. Methods Patients with primary open-angle, pigmentary, and exfoliation glaucoma, as well as healthy controls, were recruited. The instrument included questions about demographic characteristics, as well as 8 questions assessing the participant's familiarity with glaucoma. Rasch analysis was used for the validation of the questionnaire. The effect of demographics as potential determinants of awareness was examined with a multivariate logistic regression analysis. Bonferroni-corrected statistical significance was tested with the Mann-Whitney U test or one-way analysis of variance. Association between demographics and questionnaire scores was examined with Spearman correlation. Results As indicated by power analysis, responses from 175 patients (mean age 65.5 years) and 314 controls (mean age 43.3 years) were analyzed. Rasch analysis indicated no multidimensionality and good item-person targeting. Mean ± SD awareness scores for the glaucoma and control groups were 4.43±2.10 and 4.20±2.11, respectively (p=0.207). Sex and residence were not predictors of disease awareness, whereas educational level was only a determinant in the control group (p<0.001). Income was a predictor only for patients (r=0.357, p<0.001), whereas family history was predictive for both groups (p<0.001). Logistic regression analysis revealed that only family history was associated with increased awareness (χ2=4.61, p=0.03, odds ratio 1.98). Conclusions This study introduces a practical and valid instrument for the assessment of glaucoma awareness.

scholarly journals AB0212 FLARE RISK AFTER DISCONTINUING LONG-TERM METHOTREXATE TREATMENT IN PATIENTS HAVING RHEUMATOID ARTHRITIS WITH LOW DISEASE ACTIVITY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1406.1-1407
Author(s):  
S. H. Nam ◽  
J. S. Lee ◽  
S. J. Choi ◽  
W. J. Seo ◽  
J. S. Oh ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Disease Activity ◽  
Logistic Regression Analysis ◽  
Weekly Dose ◽  
Low Disease Activity ◽  
Disease Flare ◽  
The Mean

Background:Several recent studies have reported that MTX could be discontinued in patients with low disease activity who are taking biologic DMARDs or tofacitinib. However, there are limited studies on whether MTX could be discontinued in patients with low disease activity who have taken MTX for a long term.Objectives:We investigated the disease flare rate in patients with rheumatoid arthritis (RA) who achieved low disease activity following long-term methotrexate (MTX) treatment and the factors related to flare.Methods:This retrospective longitudinal cohort study included patients with RA and low disease activity who were exposed to MTX for >10 years. Disease flare was defined as an increase in DAS28 of >1.2 within 6 months of discontinuation of MTX. Logistic regression analysis was performed to identify the factors associated with flare.Results:In total, 97 patients with RA were included in the study. The mean baseline DAS28 was 1.96 ± 0.56. The median cumulative MTX dose was 11.7g; the median duration of exposure to MTX was 19 years. Following MTX discontinuation, flare occurred in 43 (44.3%) patients; the mean time to flare was 98 ± 37.7 days. According to univariable logistic regression analysis, C-reactive protein, erythrocyte sedimentation rate (ESR) at discontinuation, the average ESR in the 6 months before discontinuation of MTX, a weekly dose of MTX before discontinuation, and use of other conventional synthetic DMARDs were associated with a higher risk of disease flare. In multivariable analysis, a weekly dose of MTX before discontinuation (OR, 1.014; 95% CI, 1.014–1.342; p = 0.031) was significantly associated with flare risk.Conclusion:Among patients with RA who achieved low disease activity with long-term treatment with MTX, more than half of the patients remained flare free after MTX discontinuation. A higher MTX dose before discontinuation was associated with a high flare risk.Disclosure of Interests:None declared

scholarly journals The True-Positive Rate of a Screening Questionnaire for Temporomandib-ular Disorders

2014 ◽  
Vol 8 (1) ◽  
pp. 236-240 ◽  
Author(s):  
Akira Nishiyama ◽  
Natsuko Otomo ◽  
Kaori Tsukagoshi ◽  
Shoko Tobe ◽  
Koji Kino
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
False Negative ◽  
Mouth Opening ◽  
True Positive Rate ◽  
True Positive ◽  
Vas Score ◽  
Positive Rate ◽  
The Mean

Background: Temporomandibular disorders (TMD) occur at an incidence of 5–12% in the general population. We aimed to investigate the rate of true-positives for a screening questionnaire for TMD (SQ-TMD) and differences in the characteristics between the true-positive and false-negative groups. Materials and Methods: Seventy-six individuals (16 men, 60 women; mean age, 41.1 ± 16.5 years) were selected from pa-tients with TMD who had visited the Temporomandibular Joint Clinic at Tokyo Medical and Dental University. The patients were assessed using a questionnaire that contained items on TMD screening (SQ-TMD); pain intensity (at rest, maximum mouth-opening, and chewing), as assessed using the visual analog scale (VAS); and TMD-related limitations of daily func-tion (LDF-TMD). A logistic regression analysis was performed to assess the factors potentially influencing the true-positive rate. Results: Of the 76 subjects, 62 (81.6%) were true-positive for the questionnaire based on the SQ-TMD scores. The mean VAS score for maximum mouth-opening and chewing and the mean LDF-TMD score were significantly greater in the true-positive group than those in the false-negative group. The results of the logistic regression analysis showed that only the VAS score for chewing was a statistically significant factor (P < 0.05). Conclusion: The true-positive rate of TMD using SQ-TMD was very high. The results indicate that SQ-TMD can be used to screen TMD in patients with moderate or severe pain and difficulty in living a healthy daily life.

scholarly journals Applicability of Paediatric Index of Mortality 2 Score to Predict Outcome in Children Admitted to Paediatric Intensive Care Unit

2018 ◽  
Vol 38 (3) ◽  
pp. 149-152
Author(s):  
Shrikiran Aroor ◽  
Sandeep Kumar ◽  
Pushpa Kini ◽  
Suneel Mundkur
Keyword(s):  
Intensive Care Unit ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Intensive Care ◽  
Logistic Regression Analysis ◽  
Paediatric Intensive Care Unit ◽  
Death Rate ◽  
Paediatric Intensive Care ◽  
P Value ◽  
The Mean

Introduction: Research on critically ill children admitted to the intensive care unit has shown the usefulness of Paediatric Index of Mortality 2 (PIM2) score at admission to predict outcome. This study was conducted to estimate PIM2 score in children admitted to Paediatric Intensive Care Unit and its correlation with clinical outcome. Methods: This prospective observational study was conducted in children of age group one month to 18 years admitted to the paediatric intensive care unit of a tertiary care hospital. Data including demographics, diagnostic categories, duration of hospital stay, predicted death rate (PDR) measured by PIM2 score was compared between survivors and non survivors. Logistic regression analysis was performed to arrive at a risk adjusted relationship between the different predictor variables and the probability of death. Results: Consecutive 130 children admitted to PICU during the study period were enrolled. The mean PDR (%) of the total study population was 22.4 ± 10.60. The mean PDR in survivors was 12.4 ± 7.80 while the PDR in non survivors was 44.2 ± 12.62 (p value < 0.001). Children with PDR < 1% had a mortality rate of 2.4% when compared to 71.4% in children with PDR > 5% (p value < 0.001). PDR by PIM2 score and the presence of hypo-albuminemia remained significant even after adjusting for age in multivariate logistic regression analysis. Conclusion: PDR measured by PIM2 score differentiated well between survivors and non survivors in PICU. The predicted death rate was less than the observed death rate. PIM2 score is a useful tool to assess the severity of illness and predict outcome.

scholarly journals Agripreneurship and Agricultural Labour Market: Agripreneurial Intentions among Undergraduate Students in Ondo State, NigeriaAgripreneurship and Agricultural Labour Market: Agripreneurial Intentions among Undergraduate Students in Ondo State, Nigeria

2021 ◽  
Vol 3 (3) ◽  
pp. 76-85
Author(s):  
E. S. Ikuemonisan ◽  
A. E. Akinbola
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Labour Market ◽  
Undergraduate Students ◽  
Logistic Regression Analysis ◽  
Tertiary Institutions ◽  
Socioeconomic Characteristics ◽  
The Family ◽  
Ondo State ◽  
The Mean

This study examined agripreneurial intentions among students in the state-owned tertiary institutions in Ondo State. The study profiled students’ perceptions of learning (SPOL), teachers’ impact (SPOT), and mentorship and explored the effects of these on their agripreneurial intentions. Both descriptive and inferential statistics were used to analyze 120 students, who were randomly selected from the two state-owned tertiary institutions. A logistic regression analysis was performed to assess the effects of SPOL, SPOT, mentorship, as well as other socioeconomic characteristics, on students’ likelihood to have agripreneurial intentions. The study revealed that SPOL, SPOT & age significantly increased the likelihood of students having agripreneurial intentions, while perceptions of mentorship and the number of graduates in the family decreased it. Although the SPOL and SPOT were positive and statistically significant, the weak effects of the mean scores suggest that SPOL and SPOT should be improved upon to enhance students’ interest in agripreneurship.

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