This paper presents results from experiments on aged and seriously damaged reinforced concrete (RC) beams strengthened with different arrangements of external carbon fiber-reinforced polymer (CFRP) laminates and end anchorages. Seven RC beams from an old bridge, measuring 250 × 200 × 2300 mm, were tested. All specimens were loaded to yield load to evaluate initial mechanical properties. Then, these seriously damaged specimens were repaired using different CFRP-reinforcing schemes and reloaded to failure. The yield load growth due to CFRP reinforcement ranged from 5% to 36%. Different parameters including CFRP dimension and position, bonding length, and end anchorage were investigated and facilitated conclusions on beam ductility, load-midspan deflection response, and failure mode. This research contributes to knowledge about the CFRP repair of aged and seriously damaged beams to ensure better performance in overloaded conditions.