scholarly journals Comparable effects of moderate intensity exercise on changes in anorectic gut hormone levels and energy intake to high intensity exercise

2009 ◽  
Vol 203 (3) ◽  
pp. 357-364 ◽  
Author(s):  
Shin-ya Ueda ◽  
Takahiro Yoshikawa ◽  
Yoshihiro Katsura ◽  
Tatsuya Usui ◽  
Shigeo Fujimoto
Keyword(s):  
Energy Intake ◽  
Exercise Intensity ◽  
High Intensity ◽  
Peptide Yy ◽  
Moderate Intensity ◽  
Exercise Session ◽  
Moderate Intensity Exercise ◽  
Intensity Effect ◽  
Hormone Levels ◽  
Gut Hormone

There is growing interest in the effects of exercise on plasma gut hormone levels and subsequent energy intake (EI) but the effects of mode and exercise intensity on anorectic hormone profiles on subsequent EI remain to be elucidated. We aimed to investigate whether circulating peptide YY3–36 (PYY3–36) and glucagon-like peptide-1 (GLP-1 or GCG as listed in the HUGO Database) levels depend on exercise intensity, which could affect subsequent EI. Ten young male subjects (mean±s.d., age: 23.4±4.3 years, body mass index: 22.5±1.0 kg/m2, and maximum oxygen uptake (VO2 max): 45.9±8.5 ml/kg per min) received a standardized breakfast, which was followed by constant cycling exercise at 75% VO2 max (high intensity session), 50% VO2 max (moderate intensity session), or rest (resting session) for 30 min. At lunch, a test meal was presented, and EI was calculated. Blood samples were obtained during three sessions for measurements of glucose, insulin, PYY3–36, and GLP-1, which includes GLP-1 (7–36) amide and GLP-1 (9–36) amide. Increases in blood PYY3–36 levels were dependent on the exercise intensity (effect of session: P<0.001 by two-way ANOVA), whereas those in GLP-1 levels were similar between two different exercise sessions. Of note, increase in area under the curve values for GLP-1 levels was negatively correlated with decrease in the EI in each exercise session (high: P<0.001, moderate: P=0.002). The present findings raise the possibility that each gut hormone exhibits its specific blood kinetics in response to two different intensities of exercise stimuli and might play differential roles in regulation of EI after exercise.

scholarly journals What Doesn't Kill you Makes you Fitter: A Systematic Review of High-Intensity Interval Exercise for Patients with Cardiovascular and Metabolic Diseases

2015 ◽  
Vol 9 ◽  
pp. CMC.S26230 ◽  
Author(s):  
Itamar Levinger ◽  
Christopher S. Shaw ◽  
Nigel K. Stepto ◽  
Samantha Cassar ◽  
Andrew J. McAinch ◽  
...  
Keyword(s):  
Systematic Review ◽  
High Intensity ◽  
Metabolic Diseases ◽  
Moderate Intensity ◽  
Exercise Session ◽  
Peak Power Output ◽  
Moderate Intensity Exercise ◽  
Interval Exercise ◽  
Cardiometabolic Diseases ◽  
High Intensity Interval

High-intensity interval exercise (HIIE) has gained popularity in recent years for patients with cardiovascular and metabolic diseases. Despite potential benefits, concerns remain about the safety of the acute response (during and/or within 24 hours postexercise) to a single session of HIIE for these cohorts. Therefore, the aim of this study was to perform a systematic review to evaluate the safety of acute HIIE for people with cardiometabolic diseases. Electronic databases were searched for studies published prior to January 2015, which reported the acute responses of patients with cardiometabolic diseases to HIIE (≥80% peak power output or ≥85% peak aerobic power, VO2peak). Eleven studies met the inclusion criteria (n = 156; clinically stable, aged 27-66 years), with 13 adverse responses reported (~8% of individuals). The rate of adverse responses is somewhat higher compared to the previously reported risk during moderate-intensity exercise. Caution must be taken when prescribing HIIE to patients with cardiometabolic disease. Patients who wish to perform HIIE should be clinically stable, have had recent exposure to at least regular moderate-intensity exercise, and have appropriate supervision and monitoring during and after the exercise session.

scholarly journals Great Expectations: A Qualitative Analysis of the Factors That Influence Affective Forecasts for Exercise

2020 ◽  
Vol 17 (2) ◽  
pp. 551 ◽  
Author(s):  
Amanda J. Calder ◽  
Elaine A. Hargreaves ◽  
Ken Hodge
Keyword(s):  
Qualitative Analysis ◽  
Thematic Analysis ◽  
Exercise Intensity ◽  
Moderate Intensity ◽  
Exercise Session ◽  
Design Strategies ◽  
Moderate Intensity Exercise ◽  
Great Expectations ◽  
Exercise Participation ◽  
Exercise Environment

The extent to which people expect to feel pleasure during exercise is proposed to influence an individual’s decision to be active. In order to identify the factors that shape this affective forecast for exercise, this study explored what people think about when creating their affective forecast for exercise. Thirty-one inactive participants provided an affective forecast for a moderate intensity exercise session using the global affective forecast questionnaire. Immediately after, they were asked a series of questions to verbally explain what they were thinking about in order to generate their forecast. Thematic analysis identified four themes relating to the exercise intensity, the exercise outcomes, the exercise environment, and the enjoyment of exercise that influenced affective forecast creation. Exercise practitioners should design strategies to manipulate these factors, and structure exercise environments to support a positive affective forecast and better motivate exercise participation.

scholarly journals Breaking up prolonged sitting time with walking does not affect appetite or gut hormone concentrations but does induce an energy deficit and suppresses postprandial glycaemia in sedentary adults

2016 ◽  
Vol 41 (3) ◽  
pp. 324-331 ◽  
Author(s):  
Daniel P. Bailey ◽  
David R. Broom ◽  
Bryna C.R. Chrismas ◽  
Lee Taylor ◽  
Edward Flynn ◽  
...  
Keyword(s):  
Energy Intake ◽  
Peptide Yy ◽  
Random Order ◽  
Sitting Time ◽  
Metabolic Effects ◽  
Energy Deficit ◽  
Moderate Intensity ◽  
Prolonged Sitting ◽  
Gut Hormone ◽  
Ad Libitum

Breaking up periods of prolonged sitting can negate harmful metabolic effects but the influence on appetite and gut hormones is not understood and is investigated in this study. Thirteen sedentary (7 female) participants undertook three 5-h trials in random order: (i) uninterrupted sitting (SIT), (ii) seated with 2-min bouts of light-intensity walking every 20 min (SIT + LA), and (iii) seated with 2-min bouts of moderate-intensity walking every 20 min (SIT + MA). A standardised test drink was provided at the start of each trial and an ad libitum pasta test meal provided at the end of each trial. Subjective appetite ratings and plasma acylated ghrelin, peptide YY, insulin, and glucose were measured at regular intervals. Area under the curve (AUC) was calculated for each variable. AUC values for appetite and gut hormone concentrations were unaffected in the activity breaks conditions compared with uninterrupted sitting (linear mixed modelling: p > 0.05). Glucose AUC was lower in SIT + MA than in SIT + LA (p = 0.004) and SIT (p = 0.055). There was no difference in absolute ad libitum energy intake between conditions (p > 0.05); however, relative energy intake was lower in SIT + LA (39%; p = 0.011) and SIT + MA (120%; p < 0.001) than in SIT. In conclusion, breaking up prolonged sitting does not alter appetite and gut hormone responses to a meal over a 5-h period. Increased energy expenditure from activity breaks could promote an energy deficit that is not compensated for in a subsequent meal.

scholarly journals Exercise training modalities in chronic heart failure: does high intensity aerobic interval training make the difference?

2016 ◽  
Vol 86 (1-2) ◽  
Author(s):  
Francesco Giallauria ◽  
Neil Andrew Smart ◽  
Antonio Cittadini ◽  
Carlo Vigorito
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Exercise Training ◽  
Exercise Capacity ◽  
High Intensity ◽  
Moderate Intensity ◽  
Exercise Session ◽  
Moderate Intensity Exercise ◽  
Training Modalities ◽  
The Impact

Exercise training (ET) is strongly recommended in patients with chronic heart failure (CHF). Moderate-intensity aerobic continuous ET is the best established training modality in CHF patients. In the last decade, however, high-intensity interval exercise training (HIIT) has aroused considerable interest in cardiac rehabilitation community. Basically, HIIT consists of repeated bouts of high-intensity exercise alternated with recovery periods. In CHF patients, HIIT exerts larger improvements in exercise capacity compared to moderate-continuous ET. These results are intriguing, mostly considering that better functional capacity translates into an improvement of symptoms and quality of life. Notably, HIIT did not reveal major safety issues; although CHF patients should be clinically stable, have had recent exposure to at least regular moderate-intensity exercise, and appropriate supervision and monitoring during and after the exercise session are mandatory. The impact of HIIT on cardiac dimensions and function and on endothelial function remains uncertain. HIIT should not replace other training modalities in heart failure but should rather complement them. Combining and tailoring different ET modalities according to each patient’s baseline clinical characteristics (i.e. exercise capacity, personal needs, preferences and goals) seem the most astute approach to exercise prescription.

scholarly journals High-intensity exercise and cognitive function in cognitively normal older adults: a pilot randomised clinical trial

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Belinda M. Brown ◽  
Natalie Frost ◽  
Stephanie R. Rainey-Smith ◽  
James Doecke ◽  
Shaun Markovic ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Cardiorespiratory Fitness ◽  
Exercise Intensity ◽  
High Intensity ◽  
Randomised Clinical Trial ◽  
Trial Registration ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Cognitively Normal ◽  
Exercise Interventions

Abstract Background Physical inactivity has been consistently linked to increased risk of cognitive decline; however, studies examining the impact of exercise interventions on cognition have produced inconsistent findings. Some observational studies suggest exercise intensity may be important for inducing cognitive improvements; however, this has yet to be thoroughly examined in older adult cohorts. The objective of the current study was to evaluate the effect of systematically manipulated high-intensity and moderate-intensity exercise interventions on cognition. Methods This multi-arm pilot randomised clinical trial investigated the effects of 6 months of high-intensity exercise and moderate-intensity exercise, compared with an inactive control, on cognition. Outcome measures were assessed at pre- (baseline), post- (6 months), and 12 months post-intervention. Ninety-nine cognitively normal men and women (aged 60–80 years) were enrolled from October 2016 to November 2017. Participants that were allocated to an exercise group (i.e. high-intensity or moderate-intensity) engaged in cycle-based exercise two times per week for 6 months. Cognition was assessed using a comprehensive neuropsychological test battery. Cardiorespiratory fitness was evaluated by a graded exercise test. Results There was a dose-dependent effect of exercise intensity on cardiorespiratory fitness, whereby the high-intensity group experienced greater increases in fitness than the moderate-intensity and control groups. However, there was no direct effect of exercise on cognition. Conclusions We did not observe a direct effect of exercise on cognition. Future work in this field should be appropriately designed and powered to examine factors that may contribute to individual variability in response to intervention. Trial registration This study is registered with the Australian New Zealand Clinical Trials Registry (ACTRN12617000643370). Registered on 3 May 2017—retrospectively registered. https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=372780

scholarly journals Exercise intensity independently modulates thermal behavior during exercise recovery but not during exercise

2019 ◽  
Vol 126 (4) ◽  
pp. 1150-1159 ◽  
Author(s):  
Nicole T. Vargas ◽  
Christopher L. Chapman ◽  
Blair D. Johnson ◽  
Rob Gathercole ◽  
Zachary J. Schlader
Keyword(s):  
Thermal Behavior ◽  
Exercise Intensity ◽  
High Intensity ◽  
Weighted Average ◽  
High Intensity Exercise ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Afferent Stimulus ◽  
Skin Wettedness ◽  
Custom Made

We tested the hypothesis that thermal behavior is greater during and after high- compared with moderate-intensity exercise. In a 27°C, 20% relative humidity environment, 20 participants (10 women, 10 men) cycled for 30 min at moderate [53% (SD 6) peak oxygen uptake (V̇o2peak) or high [78% (SD 6) V̇o2peak] intensity, followed by 120 min of recovery. Mean skin and core temperatures and mean skin wettedness were recorded continuously. Participants maintained thermally comfortable neck temperatures with a custom-made neck device. Neck device temperature provided an index of thermal behavior. The weighted average of mean skin and core temperatures and mean skin wettedness provided an indication of the afferent stimulus to thermally behave. Mean skin and core temperatures were greater at end-exercise in high intensity ( P < 0.01). Core temperature remained elevated in high intensity until 70 min of recovery ( P = 0.03). Mean skin wettedness and the afferent stimulus were greater at 10–20 min of exercise in high intensity ( P ≤ 0.03) and remained elevated until 60 min of recovery ( P < 0.01). Neck device temperature was lower during exercise in high versus moderate intensity ( P ≤ 0.02). There was a strong relation between the afferent stimulus and neck device temperature during exercise (high: R2 = 0.82, P < 0.01; moderate: R2 = 0.95, P < 0.01) and recovery (high: R2 = 0.97, P < 0.01; moderate: R2 = 0.93, P < 0.01). During exercise, slope ( P = 0.49) and y-intercept ( P = 0.91) did not differ between intensities. In contrast, slope was steeper ( P < 0.01) and y-intercept was higher ( P < 0.01) during recovery from high-intensity exercise. Thermal behavior is greater during high-intensity exercise because of the greater stimulus to behave. The withdrawal of thermal behavior is augmented after high-intensity exercise. NEW & NOTEWORTHY This is the first study to determine the effects of exercise intensity on thermal behavior. We show that exercise intensity does not independently modulate thermal behavior during exercise but is dependent on the magnitude of afferent stimuli. In contrast, the withdrawal of thermal behavior after high-intensity exercise is augmented. This may be a consequence of an attenuated perceptual response to afferent stimuli, which may be due to processes underlying postexercise hypoalgesia.

Substrate metabolism during different exercise intensities in endurance-trained women

2000 ◽  
Vol 88 (5) ◽  
pp. 1707-1714 ◽  
Author(s):  
J. A. Romijn ◽  
E. F. Coyle ◽  
L. S. Sidossis ◽  
J. Rosenblatt ◽  
R. R. Wolfe
Keyword(s):  
Oxygen Uptake ◽  
Exercise Intensity ◽  
Maximal Oxygen Uptake ◽  
High Intensity ◽  
Fat Oxidation ◽  
High Intensity Exercise ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Oxidation Rates ◽  
Reported Data

We have studied eight endurance-trained women at rest and during exercise at 25, 65, and 85% of maximal oxygen uptake. The rate of appearance (Ra) of free fatty acids (FFA) was determined by infusion of [2H2]palmitate, and fat oxidation rates were determined by indirect calorimetry. Glucose kinetics were assessed with [6,6-2H2]glucose. Glucose Ra increased in relation to exercise intensity. In contrast, whereas FFA Ra was significantly increased to the same extent in low- and moderate-intensity exercise, during high-intensity exercise, FFA Ra was reduced compared with the other exercise values. Carbohydrate oxidation increased progressively with exercise intensity, whereas the highest rate of fat oxidation was during exercise at 65% of maximal oxygen uptake. After correction for differences in lean body mass, there were no differences between these results and previously reported data in endurance-trained men studied under the same conditions, except for slight differences in glucose metabolism during low-intensity exercise (Romijn JA, Coyle EF, Sidossis LS, Gastaldelli A, Horowitz JF, Endert E, and Wolfe RR. Am J Physiol Endocrinol Metab 265: E380–E391, 1993). We conclude that the patterns of changes in substrate kinetics during moderate- and high-intensity exercise are similar in trained men and women.

scholarly journals Changes in gut hormone levels and negative energy balance during aerobic exercise in obese young males

2009 ◽  
Vol 201 (1) ◽  
pp. 151-159 ◽  
Author(s):  
Shin-ya Ueda ◽  
Takahiro Yoshikawa ◽  
Yoshihiro Katsura ◽  
Tatsuya Usui ◽  
Hayato Nakao ◽  
...  
Keyword(s):  
Energy Balance ◽  
Aerobic Exercise ◽  
Energy Intake ◽  
Energy Deficit ◽  
Exercise Session ◽  
Hormone Levels ◽  
Young Males ◽  
Gut Hormone ◽  
Obese Subjects ◽  
Normal Controls

We examined whether changes in gut hormone levels due to a single bout of aerobic exercise differ between obese young males and normal controls, and attempted to determine the involvement of hormonal changes during exercise in the regulation of energy balance (EB) in these obese subjects. Seven obese and seven age-matched subjects of normal weight participated in exercise and rest sessions. Subjects consumed a standardized breakfast that was followed by constant cycling exercise at 50% VO2max or rest for 60 min. At lunch, a test meal was presented, and energy intake (EI) and relative energy intake (REI) were calculated. Blood samples were obtained at 30 min intervals during both sessions for measurement of glucose, insulin, glucagon, ghrelin, peptide YY (PYY), and glucagon-like peptide-1 (GLP-1). Plasma levels of PYY and GLP-1 were increased by exercise, whereas plasma ghrelin levels were unaffected by exercise. The areas under the curve (AUC) of the time courses of PYY and GLP-1 levels did not significantly differ between the two groups. In contrast, EI and REI were decreased by exercise in both groups, and energy deficit was significantly larger in obese subjects than in normal controls. The present findings suggest that short-term EB during a single exercise session might be regulated not by increased amounts of these gut hormones per se.

Acute high-intensity endurance exercise is more effective than moderate-intensity exercise for attenuation of postprandial triglyceride elevation

2013 ◽  
Vol 114 (6) ◽  
pp. 792-800 ◽  
Author(s):  
Justin R. Trombold ◽  
Kevin M. Christmas ◽  
Daniel R. Machin ◽  
Il-Young Kim ◽  
Edward F. Coyle
Keyword(s):  
Energy Expenditure ◽  
Exercise Intensity ◽  
High Intensity ◽  
Acute Exercise ◽  
Plasma Concentrations ◽  
Fat Oxidation ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Postprandial Triglyceride ◽  
Experimental Treatments

Acute exercise has been shown to attenuate postprandial plasma triglyceride elevation (PPTG). However, the direct contribution of exercise intensity is less well understood. The purpose of this study was to examine the effects of exercise intensity on PPTG and postprandial fat oxidation. One of three experimental treatments was performed in healthy young men ( n = 6): nonexercise control (CON), moderate-intensity exercise (MIE; 50% V̇o2peak for 60 min), or isoenergetic high-intensity exercise (HIE; alternating 2 min at 25% and 2 min at 90% V̇o2peak). The morning after the exercise, a standardized meal was provided (16 kcal/kg BM, 1.02 g fat/kg, 1.36 g CHO/kg, 0.31 g PRO/kg), and measurements of plasma concentrations of triglyceride (TG), glucose, insulin, and β-hydroxybutyrate were made in the fasted condition and hourly for 6 h postprandial. Indirect calorimetry was used to determine fat oxidation in the fasted condition and 2, 4, and 6 h postprandial. Compared with CON, both MIE and HIE significantly attenuated PPTG [incremental AUC; 75.2 (15.5%), P = 0.033, and 54.9 (13.5%), P = 0.001], with HIE also significantly lower than MIE ( P = 0.03). Postprandial fat oxidation was significantly higher in MIE [83.3 (10.6%) of total energy expenditure] and HIE [89.1 (9.8) %total] compared with CON [69.0 (16.1) %total, P = 0.039, and P = 0.018, respectively], with HIE significantly greater than MIE ( P = 0.012). We conclude that, despite similar energy expenditure, HIE was more effective than MIE for lowering PPTG and increasing postprandial fat oxidation.

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