TESTOSTERONE CONCENTRATION IN THE FLUIDS OF SEMINIFEROUS TUBULES, THE INTERSTITIUM AND THE RETE TESTIS OF THE RAT

1976 ◽  
Vol 70 (2) ◽  
pp. 229-235 ◽  
Author(s):  
F. H. COMHAIRE ◽  
A. VERMEULEN
Keyword(s):  
Interstitial Fluid ◽  
Limit Of Detection ◽  
Mean Value ◽  
Rete Testis ◽  
Seminiferous Tubules ◽  
Testosterone Concentration ◽  
Anaesthetized Rats ◽  
The Mean ◽  
The Difference

SUMMARY Testosterone was measured by radioimmunoassay in interstitial fluid, 'free-flow' seminiferous tubular fluid, obtained by micropuncture, and rete testis fluid from intact adult anaesthetized rats. Under non-stimulated conditions the concentration of testosterone in interstitial fluid was below the limit of detection in two rats and achieved a mean level of 150 ± 27 (s.e.m.) ng/ml in the remaining 17 determinations. The testosterone concentration of the seminiferous tubular fluid was below the limit of detection in two rats, and had a mean level in the remaining 15 determinations of 91 ± 14 ng/ml, which is significantly lower (P < 0·02) than that in interstitial fluid. The mean ratio of seminiferous tubular:interstitial fluid testosterone concentration calculated in 14 rats was 0·94 ± 0·24. This ratio was less than unity whenever the interstitial fluid testosterone concentration was more than 50 ng/ml, whereas in all animals with interstitial fluid testosterone of 50 ng/ml, or less, the ratio was greater than or equal to one. The mean testosterone concentration of rete testis fluid in 32 samples was 33 ± 3 ng/ml. After HCG stimulation in 12 rats, testosterone concentration in interstitial fluid increased to a mean value of 660 ± 83 ng/ml, and in seminiferous tubular fluid to 460 ± 44 ng/ml; the difference between the two was significant (P < 0·05). These results are discussed in relation to the presumed dilution of seminiferous tubular fluid in rete testis fluid and the role of androgen-binding proteins in the transport of steroids.

Seasonal trends in the stable isotopic composition of snow and meltwater runoff in a subarctic catchment at Okstindan, Norway

2004 ◽  
Vol 35 (2) ◽  
pp. 119-137 ◽  
Author(s):  
S.D. Gurney ◽  
D.S.L. Lawrence
Keyword(s):  
Isotopic Composition ◽  
Mean Value ◽  
Mean Values ◽  
Stable Isotopic Composition ◽  
Meltwater Runoff ◽  
Stable Isotopic ◽  
The Mean ◽  
The Difference ◽  
Δ18o And Δd

Seasonal variations in the stable isotopic composition of snow and meltwater were investigated in a sub-arctic, mountainous, but non-glacial, catchment at Okstindan in northern Norway based on analyses of δ18O and δD. Samples were collected during four field periods (August 1998; April 1999; June 1999 and August 1999) at three sites lying on an altitudinal transect (740–970 m a.s.l.). Snowpack data display an increase in the mean values of δ18O (increasing from a mean value of −13.51 to −11.49‰ between April and August), as well as a decrease in variability through the melt period. Comparison with a regional meteoric water line indicates that the slope of the δ18O–δD line for the snowpacks decreases over the same period, dropping from 7.49 to approximately 6.2.This change points to the role of evaporation in snowpack ablation and is confirmed by the vertical profile of deuterium excess. Snowpack seepage data, although limited, also suggest reduced values of δD, as might be associated with local evaporation during meltwater generation. In general, meltwaters were depleted in δ18O relative to the source snowpack at the peak of the melt (June), but later in the year (August) the difference between the two was not statistically significant. The diurnal pattern of isotopic composition indicates that the most depleted meltwaters coincide with the peak in temperature and, hence, meltwater production.

TESTOSTERONE IN RETE TESTIS FLUID AND BLOOD OF RAMS AND RATS

1974 ◽  
Vol 62 (3) ◽  
pp. 619-629 ◽  
Author(s):  
T. G. COOPER ◽  
G. M. H. WAITES
Keyword(s):  
Venous Blood ◽  
Rete Testis ◽  
Jugular Veins ◽  
Testosterone Concentration ◽  
Efferent Duct ◽  
Duct Ligation ◽  
Anaesthetized Rats ◽  
Arterial Inflow ◽  
The Mean ◽  
Mean Concentration

SUMMARY Rete testis fluid (RTF) was collected from six conscious Clun Forest rams by cannulation of the efferent ducts, and from anaesthetized rats by cannulation of the rete testis 16–24 h after efferent duct ligation. Testosterone concentration in this fluid was measured by radioimmunoassay and compared with levels in blood collected from the subcapsular testicular artery and veins and spermatic and jugular veins. The testosterone concentration in ram RTF fluctuated from nondetectable (< 100 pg/ml) levels to approximately 20 ng/ml over 1–25 h collection periods. The mean concentration was 8·5 ± 1·2 (s.e.m.). This value was approximately one fifth the mean concentration of testosterone in samples from the testicular veins at the dorsal pole of the testis. Testosterone concentration (ng/ml) in rat RTF collected under sodium pentobarbitone anaesthesia was 26·4 ± 2·7 (18 measurements, 18 rats). A lower value was obtained when ether was the anaesthetic used during efferent duct ligation (ether, 20·3; halothane, 29·9; sodium pentobarbitone, 29·1). The mean concentration of testosterone in the RTF was similar to that in testicular venous blood (29·8 ± 3·9; 27 measurements, 27 rats), although the highest values were obtained after ether anaesthesia (ether, 38·3; halothane, 29·0; sodium pentobarbitone, 21·7). Testosterone concentration in the testicular arterial inflow was similar to that in jugular venous blood in the ram but exceeded carotid arterial levels in the rat. The values reported are used to discuss: the origin and significance of androgens in rete testis fluid, species differences, the effect of anaesthetics and season, and vascular exchange of testosterone in the spermatic cord.

Gambaran Pemberian Terapi Latihan Dalam Peningkatan Kemampuan Fungsional Tangan Pada De Quervain Syndrome: Literatur Review

2021 ◽  
Vol 1 ◽  
pp. 439-445
Author(s):  
Chandra Arum Pramitha ◽  
Wahyu Ersila
Keyword(s):  
Exercise Therapy ◽  
Functional Ability ◽  
Tendon Sheath ◽  
Mean Value ◽  
Test Results ◽  
De Quervain ◽  
The Mean ◽  
The Difference ◽  
Therapy Intervention

AbstractBody part have an important role in various activities, excess activity can cause disturbance. Musculoskeletas disorder that commonly occur due to continuous activity are tendinitis, bursitis and tenosinovitys. De Quervain Syndrome is a tendinitis disorder caused by inflammation of the tendon sheath of the muscle in the m.abductor policis longus and m. Extensor policis brevis due to thickening of the extensor retinaculum, an important role of physiotherapy in the rehabilitation of movement disorder, namely use of modalities. The purpose of tis study is te see the description of the provision of exercise terapy in improving the functional ability of the hands in the case of De Quervain Syndrome. The method in this research design uses a literature review analysis wit the PICO method with a database seachr method through PUBMED, Z-Library and Google schoolar, five articles are reviewed. The test results of increasing functional ability in patients with De Quervain Syndrome showed that there was a significant effect of exercise therapy intervention with a mean value before the action of 50,5 and the mean value after of 26,8 the difference in ability improvement was 23,7. Health woekers can improve physiotherapy in patients with De Quervain Syndrome to improve te functional ability of the hand.Keywords: De Quervain syndrome, Exercise therapy, Disabilities Of The Arm, Shoulder And Hand (DASH) AbstrakBagian tubuh memiliki peran penting dalam berbagai aktivitas, aktivitas berlebih dapat menyebabkan gangguan. Gangguan Muskuloskeletal yang umum terjadi akibat aktifitas secara terus menerus yaitu Tendinitis, bursitis dan tenosinivitys. De quervain Syndrome merupakan salah satu gangguan tendinitis yang disebabkan oleh peradangan selubung tendon otot pada m. abduktor policis longus dan m. Ekstensor policis brevis akibat penebalan pada ekstensor retinaculum, peran penting fisioterapi dalam rehabilitasi gangguan fungsi gerak tubuh yaitu penggunaan modalitas. Tujuan penelitian ini melihat gambaran pemberian terapi latihan dalam meningkatkan kemampuan fungsional tangan pada kasus De Quervain Syndrome. Metode dalam desain penelitian ini menggunakan analisis literatur review dengan metode PICO dengan metode penelusuran database melalui PUBMED, Z-Library dan Google Scholar diperoleh lima artikel yang direview. Hasil uji peningkatan kemampuan fungsional pada pasien De quervain Syndrome menunjukan ada pengaruh signifikan intervensi terapi latihan dengan nilai mean sebelum tindakan 50,5 dan nilai mean setelah dilakukan 26,8 selisih peningkatan kemampuan 23,7. Tenaga Kesehatan dapat meningkatkan Fisioterapi pada penderita De Quervain Syndrome untuk meningkatkan kemampuan fungsional tangan.Kata kunci: De quervain syndrome, Terapi latihan, Disabilities Of The Arm, Shoulder And Hand (DASH)

Long-term dynamics and destruction of marsh vegetation in the Kolokolkova Bay of the Barents Sea

2012 ◽  
pp. 66-77 ◽  
Author(s):  
I. A. Lavrinenko ◽  
O. V. Lavrinenko ◽  
D. V. Dobrynin
Keyword(s):  
Species Composition ◽  
Plant Communities ◽  
Barents Sea ◽  
Mean Value ◽  
Marsh Vegetation ◽  
Composition And Structure ◽  
The Mean ◽  
Species Composition And Structure

The satellite images show that the area of marshes in the Kolokolkova bay was notstable during the period from 1973 up to 2011. Until 2010 it varied from 357 to 636 ha. After a severe storm happened on July 24–25, 2010 the total area of marshes was reduced up to 43–50 ha. The mean value of NDVI for studied marshes, reflecting the green biomass, varied from 0.13 to 0.32 before the storm in 2010, after the storm the NDVI decreased to 0.10, in 2011 — 0.03. A comparative analysis of species composition and structure of plant communities described in 2002 and 2011, allowed to evaluate the vegetation changes of marshes of the different topographic levels. They are fol­lowing: a total destruction of plant communities of the ass. Puccinellietum phryganodis and ass. Caricetum subspathaceae on low and middle marches; increasing role of halophytic species in plant communities of the ass. Caricetum glareosae vic. Calamagrostis deschampsioides subass. typicum on middle marches; some changes in species composition and structure of plant communities of the ass. Caricetum glareosae vic. Calamagrostis deschampsioides subass. festucetosum rubrae on high marches and ass. Parnassio palustris–Salicetum reptantis in transition zone between marches and tundra without changes of their syntaxonomy; a death of moss cover in plant communities of the ass. Caricetum mackenziei var. Warnstorfia exannulata on brackish coastal bogs. The possible reasons of dramatic vegetation dynamics are discussed. The dating of the storm makes it possible to observe the directions and rates of the succession of marches vegetation.

scholarly journals Lateral Antebrachial Cutaneous Nerve as a Donor Source for Digital Nerve Grafting: A Concept Revisited

2017 ◽  
Vol 11 (1) ◽  
pp. 1041-1048 ◽  
Author(s):  
Mehmet Bekir Unal ◽  
Kemal Gokkus ◽  
Evrim Sirin ◽  
Eren Cansü
Keyword(s):  
Pearson Correlation ◽  
Mean Value ◽  
Cutaneous Nerve ◽  
Digital Nerve ◽  
Mean Values ◽  
Nerve Grafts ◽  
The Mean ◽  
The Difference ◽  
Mean Time

Objective: The main objective of this study is to evaluate the availability of lateral antebrachial cutaneous nerve (LACN) autograft for acute or delayed repair of segmented digital nerve injuries. Patients and Methods: 13 digital nerve defects of 11 patients; treated with interposition of LACN graft that harvested from ipsilateral extremity were included in the study. Mean follow up period was 35, 7 months. The mean time from injury to grafting is 53, 3 days. The results of the mean 2PDT and SWMT values of injured /uninjured finger at the end of follow up period were evaluated with Paired T test. The correlation between the defect length and the difference of 2PDT, SWMT values between the uninjured and injured finger at the end of follow up period; were evaluated with Pearson - correlation analysis. Results: The mean value of our 2PDT and SWMT results are ~5,923, ~3, 52, respectively in which can be interpreted between the normal and diminished light touch. The defect length and difference percentage of SWMT values is positively and significantly correlated statistically. Mean length of interposed nerve grafts was 18.5 mm. The age of the patient and the mean values of 2PDT and SWMT with the difference % of 2PDT and % of SWMT are not statistically correlated. Conclusion: Based on results regarding sensory regaining at recipient side and negligible sensory deficit at harvesting side, we suggest that lateral antebrachial cutaneous nerve might be a valuable graft option for digital nerve defects.

scholarly journals True and Pseudo Cholinesterase levels in short and long-term of pesticides exposures

2020 ◽  
pp. 9-12
Author(s):  
Mohammed Abdul Rahman ◽  
Raghunatha Rao D ◽  
Vasantha L
Keyword(s):  
Whole Blood ◽  
Acute Poisoning ◽  
Mean Value ◽  
Serum Cholinesterase ◽  
Control Group ◽  
Study Group ◽  
Chronic Poisoning ◽  
The Mean ◽  
The Difference ◽  
And Control

The present study is aimed to study and analyze the true and pseudo Cholinesterase levels in the subjects exposed to pesticides during short term by intentional or accidental intake and long term exposure due to their occupation were studied at Department of Biochemistry, SVS medical college and hospital mahbubnagar district. Whole blood cholinesterase levels and Pseudo cholinesterase levels were estimated. 150 people were taken as controls who had no medical illness and a total number of 300 cases of pesticide poisoning were selected, aged between 20 to 55 years, which consist of 150 acute poisoning and 150 chronic poisoning subjects in Mahbubnagar district, were taken as case study, the detailed case history and the type of organophosphorus pesticide taken were recorded. Mean and standard deviation (S.D) of all variables were calculated and compared with those of controls. Statistical significance was assessed and P-value <0.05 were considered significant.           During acute poisoning the mean value of Whole blood cholinesterase/True cholinesterase (U / L) in acute poisoning cases on first day was 1.267± 0.612 on 3th day was 1.651±0.647, on 7th day was 2.221±0.684 and at the end of 6 months was 3.970±0.404.The difference between the study group and control group (4.0 ± 0.39) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in acute poisoning cases on first day was 2213.05 ± 1749.81, on 3th day was 2862.3 ± 2025.6, on 7th day was 4008.4 ± 2355.9 and at the end of 6 months was 7708.34 ± 880.72.The difference between the study group and control group (7991.97 ± 1276.5) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. During chronic poisoning (exposure) the mean value of Whole blood cholinesterase (U/L) in controls is 4.0 ± 0.39 as compared to 3.019 ± 0.848 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in controls was 7991.97 ± 1276.5 as compared to 6214 ± 1189 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant.

scholarly journals Role of Chemical Biomarkers in Prediction of Intra-Amniotic Infection in Cases with Preterm Premature Rupture of Membrane, Observational Study

2019 ◽  
Vol 3 (2) ◽  
Keyword(s):  
Interleukin 6 ◽  
Mean Value ◽  
Maternal Serum ◽  
P Value ◽  
Subclinical Infection ◽  
Premature Rupture ◽  
Cutoff Value ◽  
The Mean ◽  
Sensitivity Specificity

Introduction: Early recognition of subclinical intra-amniotic infection before development of clinical Chorioamnionitis dramatically improve neonatal outcome before affection of fetal neurological function. Objective: this study was conducted to evaluate the role of procalcitonin and interleukin-6 in early prediction of intrauterine infection in pregnant women with premature rupture of membranes. Methods: This observational prospective cohort study was conducted on 100 pregnant women with preterm premature rupture of membrane (PPROM), Patients were divided into 2 groups: Group I: with normal CRP and WBCs level. Group2: with subclinical infection which was detected by elevated WBCs count >15,000 c/mm3 and / or positive CRP. This group was divided into two groups (Group (II) and Group (III) according to development of Chorioamnionitis. follow up of these patients was done to detect the cutoff value of procalcitonin and interleukin-6 as a predictive indicator of clinical intra-amniotic infection in patients with premature rupture of membrane. Results: This study showed that the mean value of maternal serum PCT concentration was higher in patients with clinical infection than its concentration in patients without infection or with subclinical infection with P-value 0.0001 which is highly significant between the studied cases and with cutoff value was >0.67ng/ml, sensitivity, specificity, PPV, NPV was 88.7%, 42.9%, 79.7% and 60% respectively and the mean value of maternal serum IL-6 concentration was also higher in patients with clinical infection than its concentration in patients without infection or with subclinical infection with P-value 0.001which is highly significant between the studied cases and with cutoff value was >11.1pg/ ml, sensitivity, specificity, PPV, NPV was 67.9%, 61.9%, 81.8% and 43.3% respectively. Conclusion: maternal serum procalcitonin is a good predictor of clinical intra-amniotic infection with good sensitivity, specificity, PPV, NPV which is nearly good as CRP which is better than serum interleukin-6 regarding sensitivity

scholarly journals THE LUCK IN “TALENT VERSUS LUCK” MODELING

2020 ◽  
Vol 23 (03) ◽  
pp. 2050007
Author(s):  
SEAN ELVIDGE
Keyword(s):  
Mean Value ◽  
Maximum Amount ◽  
Random Numbers ◽  
Individual Parameter ◽  
Input Parameters ◽  
The Mean ◽  
Model Variability ◽  
The Impact ◽  
The Relationship

This paper further investigates the Talent versus Luck (TvL) model described by [Pluchino et al. Talent versus luck: The role of randomness in success and failure, Adv. Complex Syst. 21 (2018) 1850014] which models the relationship between ‘talent’ and ‘luck’ on the impact of an individuals career. It is shown that the model is very sensitive to both random sampling and the choice of value for the input parameters. Running the model repeatedly with the same set of input parameters gives a range of output values of over 50% of the mean value. The sensitivity of the inputs of the model is analyzed using a variance-based approach based upon generating Sobol sequences of quasi-random numbers. When using the model to look at the talent associated with an individual who has the maximum capital over a model run it has been shown that the choice for the standard deviation of the talent distribution contributes to 67% of the model variability. When investigating the maximum amount of capital returned by the model the probability of a lucky event at any given epoch has the largest impact on the model, almost three times more than any other individual parameter. Consequently, during the analysis of the model results one must keep in mind the impact that only small changes in the input parameters can have on the model output.

Hyperaggregability Of Platelets In Cancer, Especially In Reference To Genesis Of DIC

1981 ◽  
Author(s):  
H Yamazaki ◽  
Y Yahara ◽  
T Motomiya ◽  
K Tanoue ◽  
I Isohisa ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Time Course ◽  
Mean Value ◽  
Activated Partial Thromboplastin Time ◽  
Healthy Controls ◽  
Triggering Mechanism ◽  
Coagulation Abnormalities ◽  
Activated Platelets ◽  
The Mean

To clarify the role of platelets in the genesis of DIC in cancer, platelets of cancer patients with and without DIC were examined. Patients studied were 29 cases with cancer in stomach, 17 in lung, 7 in pancreas, 6 in liver (hepatoma), 6 in throat, nose and jaw, 2 in the gall bladder and bilary duct, 2 in uterus and 1 each in the small bowel, rectum and prostate, and 1 each with osteosarcoma, mesothelioma and chorionepithelioma. All patients were in stage 3 or 4. 105 healthy controls were also studied. They were evaluated on a scale of coagulation abnormalities, one point was given for each of the following criteria full-filled, and the score (0 to 4) was used. 1. Platelet count<150xl03Anl. 2. Prothrombin time prolonged more than 1 sec over control and/or activated partial thromboplastin time prolonged more than 10 sec over control. 3. Fibrinogen<250 mg/dl (mean fibrinogen value of the cancer patients minus 1 SD). 4. FDP>20 µg/ml. The patients were distributed with 27 % for score 0, 38 % for 1, 20 % for 2, 7 % for 3 and 8 % for 4. Degrees of abnormality in groups with scores of 3 and 4 were significant when compared to scores 0 and 1, but score 2 was not clearly distinguishable. Platelet mode volume in score 4 was smaller than the other groups. Platelet aggregation by adrenaline and ADP decreased in score 3 and 4, while it increased significantly in score 0 and 1 respectively (P<0.01 -0.05). The mean value of plasma β-TG in the cancer patients as a whole (44±24 ng/ml) was significantly higher than that of control (22±13 ng/ml)(P<0.01). PF4 showed the same tendency. During the time course of the disease, hyperaggrega- bility of platelets associated with increases in β-TG and PF4 was observed before an appearance of DIC syndrome in several cases. The results suggest the existence of hyperfunction of platelets in cancer patients and the possibility of triggering mechanism of such activated platelets in the genesis of DIC in cancer.

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