scholarly journals Strength Abilities: Modeling of Immediate and Delayed Training Effect of Strength Loads in Boys Aged 8 Years

2020 ◽  
Vol 20 (4) ◽  
pp. 248-255
Author(s):  
Oleg Khudolii ◽  
Sergii Iermakov ◽  
Olha Ivashchenko ◽  
Mykola Nosko
Keyword(s):  
Factorial Design ◽  
Regression Models ◽  
Training Effect ◽  
Regression Equations ◽  
Interval Duration ◽  
Rest Interval ◽  
Strength Exercises ◽  
Study Results ◽  
The Impact ◽  
Full Factorial

The purpose of the study was to obtain regression models of immediate and delayed training effect of strength loads in boys aged 8 years, based on a full factorial experiment. Materials and methods. The study participants were 48 boys aged 8 years. The experiment was performed using a 22 factorial design. The study materials were processed by the IBM SPSS 22 statistical analysis program. The study examined the impact of four variants of strength load on the immediate (ITE) and the delayed (DTE) training effect of orthogonal strength exercises modes and rest intervals in boys aged 8 years. Results. The study results show that in the proposed matrix of the 22 full factorial design, the chosen step of variation of factors is sufficient to study the influence of different modes of strength exercises on the dynamics of ITE in boys aged 8 years. Based on the data analysis, the study obtained regression models of load for calculating the ITE1, ITE2, and DTE. The obtained regression models make it possible to calculate the number of repetitions and rest interval to achieve the most rational load variant. Conclusions. The analysis of regression equations shows the interrelation between training effects: ITE1 —> ITE2 —> DTE. The value of ITE1, ITE2, and DTE at station I (exercises to strengthen arms and shoulders) and station II (exercises to strengthen abdominal muscles) depends on the increase in the number of repetitions in a set and the duration of the rest interval. The value of ITE1, ITE2 at station ІІІ (exercises to strengthen back muscles) depends on the increase in the number of repetitions in a set and the duration of the rest interval. The value of DTE – on the increase in the number of repetitions in a set and the reduction of the rest interval duration. The value of ITE1 at station IV (exercises to strengthen leg muscles) depends on the increase in the number of repetitions in a set and the reduction of the rest interval duration. To strengthen the DTE, it is necessary to reduce the number of repetitions in a set and the duration of the rest interval.

scholarly journals Strength Abilities: Estimation of Immediate Training Effect of Strength Loads in Girls Aged 7 Years

2019 ◽  
Vol 19 (2) ◽  
pp. 98-104 ◽  
Author(s):  
O. M. Khudolii ◽  
O. V. Ivashchenko ◽  
S. S. Iermakov ◽  
Yu. M. Nosko ◽  
S. I. Marchenko
Keyword(s):  
Experiment Planning ◽  
Abdominal Muscles ◽  
Rest Interval ◽  
Mathematical Experiment ◽  
Leg Muscles ◽  
Strength Exercises ◽  
Study Results ◽  
Study Participants ◽  
Full Factorial ◽  
Mathematical Experiment Planning

The study purpose was to experimentally substantiate technological approaches to estimating training effects of strength loads in girls aged 7 years. Materials and methods. The study participants were girls aged 7 years (n = 40). The children and their parents were fully informed about all the features of the study and gave their consent to participate in the experiment. To solve the tasks set, theoretical and empirical methods were used: analysis and generalization of scientific and methodological literature; modeling, pedagogical observation and experiment, methods of mathematical experiment planning (2k type FFE). Results. The study results show that in the proposed matrix of the 22 type full factorial experiment design, the chosen step of variation of factors is sufficient to study the influence of different modes of strength exercises on the dynamics of ITE in girls aged 7 years. Conclusions. At station 1 (exercises to strengthen arms and shoulders), the ITE in girls aged 7 is most influenced by the interaction between the number of repetitions in a set and the rest interval (x1x2) – 83%, the number of repetitions in a set (x1) – 15%; at station 2 (exercises to strengthen abdominal muscles), it is most influenced by the number of repetitions in a set (x1) – 48.5%, the rest interval (х2) – 48.5%; at station 3 (exercises to strengthen back muscles) – by the rest interval (x2) – 82%; at station 4 (exercises to strengthen leg muscles) – by the rest interval (x2) – 92%. At stations 1–3, to strengthen the ITE, it is necessary to increase the number of repetitions in a set and the duration of the rest interval, at station 4, it is necessary to increase the number of repetitions in a set and to reduce the duration of the rest interval.

Abstract W P302: Assessment of a New Method of Warfarin Management vs the New Oral Anticoagulants and Conventional Warfarin Management in Atrial Fibrillation

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Henry I Bussey ◽  
Edith Nutescu
Keyword(s):  
Atrial Fibrillation ◽  
Oral Anticoagulants ◽  
New Oral Anticoagulants ◽  
Target Range ◽  
Regression Equations ◽  
Major Event ◽  
Cost Avoidance ◽  
Study Results ◽  
Event Rates ◽  
The Impact

PURPOSE: To assess the impact of International Normalized Ratio (INR) self testing and online remote monitoring and management (STORM2) on clinical events and costs vs. traditional warfarin management and the new oral anticoagulants (NOACs) in atrial fibrillation (AF). METHODS: Seven STORM2 trials had a weighted mean INR time in the target range (TTR) of 77.2%. Thromboembolism (TE) and major bleeding (MB) rates at 30%, 45%, 55%, 65%, and 75% TTR were calculated using linear regression equations from a systematic review of 38 AF studies. MB = 10.104 - 0.120x[TTR], (p = 0.004) and TE = 8.313 - 0.098x[TTR], (p = 0.03). MB and TE rates were sub-divided based on the distribution in the NOAC trials. TTR-based mortality was calculated based on a 6%/yr rate multiplied by the adjusted relative risks from a data base analysis of approximately 38,000 AF patients. Projected event rates at 75% TTR, expressed as number per 1,000 patient-years, were compared to event rates at lower TTR ranges and to rates reported in the NOAC trials. Differences in major event rates were used to calculate cost avoidance. RESULTS: Projected event rates with STORM2 (TTR of 75%) when compared to “conventional ” TTR of 55% to 65% were 64% to 71% lower for MB, 47% to 64% lower for TE, and 47% to 57% lower for mortality. Compared to the NOAC study results, the projected rates were 48% to 70% lower for MB, 41% to 66% lower for TE, and 40% to 53% lower for mortality. Projected cost avoidance was $10.4 million vs. a TTR of < 30%, $2.2 million vs. a TTR of 65%; and from $1.4 to $3.1 million vs the NOACs. Costs of “other” MB and TE , drug costs, and monitoring costs were not included in the estimates. CONCLUSIONS: STORM2 management of warfarin is projected to produce a 50% or greater reduction in major event rates with a cost avoidance of $1.4 to $10.4 million per 1,000 patients per year. CLINICAL IMPLICATIONS: STORM2 management may transform the safety and efficacy of anticoagulation for the millions of people with AF while substantially reducing costs. These findings warrant randomized, prospective trials in AF and other indications for anticoagulation.

scholarly journals Body Composition in Community-Dwelling Older Adults Before and After SARS-CoV-2 Infection: A Longitudinal Prospective Study in a Rural Village Struck by the Pandemic

2021 ◽  
Vol 12 ◽  
pp. 215013272110477
Author(s):  
Oscar H. Del Brutto ◽  
Robertino M. Mera ◽  
Denisse A. Rumbea ◽  
Pedro Pérez ◽  
Bettsy Y. Recalde ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Body Composition ◽  
Regression Models ◽  
Community Dwelling ◽  
The Body ◽  
Study Results ◽  
The Impact ◽  
Community Dwelling Older Adults

Background: Information on the body composition of inhabitants of remote communities during the SARS-CoV-2 pandemic is limited. Using a longitudinal population-based study design, we assessed the association between SARS-CoV-2 infection and changes in body composition. Methods: Community-dwelling older adults living in a rural Ecuadorian village received body composition determinations before and 1 year after the pandemic as well as serological tests for detection of SARS-CoV-2 antibodies. The independent association between SARS-CoV-2 infection and abnormalities in body composition at follow-up was assessed by fitting linear mixed models for longitudinal data. Results: Of 327 enrolled individuals, 277 (85%) received baseline and follow-up body composition determinations, and 175 (63%) of them became SARS-CoV-2 seropositive. Overall, diet and physical activity deteriorated during the follow-up. Multivariate random-effects generalized least squares regression models that included the impact of time and seropositivity on follow-up body composition, showed that neither variable contributed to a worsening in body composition. Multivariate logistic regression models disclosed that the serological status at follow-up cannot be predicted by differences in body composition and other baseline covariates. Conclusions: Study results suggest no increased susceptibility to SARS-CoV-2 infection among older adults with abnormal body composition and no significant changes as a result of worse physical activity and dietary habits or seropositivity during the length of the study. Together with a previous study in the same population that showed decrease in hand-grip strength after SARS-CoV-2, results confirm that dynapenia (and not sarcopenia) is associated with SARS-CoV-2 infection in older adults.

Strength abilities: pattern recognition method in the management of the cumulative effect of strength loads in 8-year-old boys

2021 ◽  
Vol 25 (4) ◽  
pp. 253-260
Author(s):  
Olha Ivashchenko ◽  
Oleg Khudolii ◽  
Wladyslaw Jagiello
Keyword(s):  
Pattern Recognition ◽  
Discriminant Analysis ◽  
Strength Training ◽  
Cumulative Effect ◽  
Training Effect ◽  
Pattern Recognition Method ◽  
Recognition Method ◽  
The Third ◽  
Strength Exercises ◽  
The Impact

Background and Study Aim. The purpose of the study was to determine the peculiarities of using pattern recognition method in the management of the cumulative effect of strength loads in 8-year-old boys. Materials and methods. The study participants were 48 boys aged 8. The experiment was conducted using a 22 factorial design. The study materials were processed by the IBM SPSS 22 statistical analysis program. Discriminant analysis was performed. The study examined the impact of four variants of strength load on the formation of the cumulative training effect of three, six, nine, and twelve classes in 8-year-old boys. Results. The discriminant analysis provided information about the impact of four orthogonal variants of strength loads on the formation of the cumulative training effect of strength exercises of three, six, nine, and twelve classes in 8-year-old boys. The obtained data make it possible to choose a load mode at each step of the CTE formation and to manage schoolchildren’s strength training. Conclusions. The verification of the obtained discriminant functions shows their high discriminative ability and value in interpretation with respect to the general population (p < 0.05). It was found that the formation of the CTE of three classes is most influenced by the third load variant, six classes – by the third load variant, nine classes – the third load variant, twelve classes – the first load variant. The discriminant function structure coefficients made it possible to identify the factor structure of the CTE of 3, 6, 9, 12 classes, to find that the CTE3, CTE6 are associated with the work at the first place “Exercises to strengthen arm muscles”, the CTE9, CTE12 – with the work at the third (“Exercises to strengthen back muscles”) and the fourth (“Exercises to strengthen leg muscles”) places. The CTE of three, six, nine, and twelve classes depends on the modes of strength exercises and has different focuses. The CTE3 – speed and strength focus; CTE6, 9 – comprehensive focus; CTE12 – explosive-strength focus. The obtained values of centroids for the CTE of 3, 6, 9, 12 classes enable the management of schoolchildren’s strength training.

scholarly journals Influence of dependent variables on granule formulation using factorial design: microwave irradiation as one of the factor

2013 ◽  
Vol 2 (7) ◽  
pp. 115-118 ◽  
Author(s):  
Prameela Rani Avula ◽  
Hema Veesam
Keyword(s):  
Factorial Design ◽  
Pharmaceutical Journal ◽  
Flow Property ◽  
Dosage Forms ◽  
Regression Equations ◽  
Dependent Variables ◽  
Granule Formulation ◽  
Traditional Drug ◽  
Contour Plots ◽  
The Impact

As traditional drug delivery poses many disadvantages such as difficulty in consumption, the granules were opted to replace tablet dosage forms available in the market. A 23 full factorial design was employed for the formulation and characterization of the granule dosage form of oxcarbazepine. From regression equations we can assess the impact of each factor on the response further contour plots helped to pre-analyze the desired target factor values, in addition optimization process helped to analyze the values of dependent variables. Thus as of the results achieved a preferred response of flow property and drug release was obtained. In the current study, an attempt has been made to minimize possible number of experiments in the formulation of granule dosage forms. Polyvidone is a hydrophilic binder and primellose is a good disintegrate to obtain higher dissolution rate. A part, microwave assisted drying process plays a major role in achieving desired flow properties of granules.DOI: http://dx.doi.org/10.3329/icpj.v2i7.15153 International Current Pharmaceutical Journal, June 2013, 2(7): 115-118

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