Enhanced Mechanical Strength of β-Chitosan Nanofiber Films via Aqueous Counter Collision Treatment

2020 ◽  
Vol 25 (3) ◽  
pp. 148-153
Author(s):  
Seyeon Jang ◽  
Joong-Kwon Kim ◽  
Jungho Jin
Nanomaterials ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1752 ◽  
Author(s):  
Le Van Hai ◽  
Lindong Zhai ◽  
Hyun Chan Kim ◽  
Pooja S. Panicker ◽  
Duc Hoa Pham ◽  
...  

This paper reports that, by simply blending two heterogeneous polysaccharide nanofibers, namely chitosan nanofiber (ChNF) and cellulose nanofiber (CNF), a ChNF–CNF composite was prepared, which exhibited improved mechanical properties and antioxidant activity. ChNF was isolated using the aqueous counter collision (ACC) method, while CNF was isolated using the combination of TEMPO oxidation and the ACC method, which resulted in smaller size of CNF than that of ChNF. The prepared composite was characterized in terms of morphologies, FT-IR, UV visible, thermal stability, mechanical properties, hygroscopic behaviors, and antioxidant activity. The composite was flexible enough to be bent without cracking. Better UV-light protection was shown at higher content of ChNF in the composite. The high ChNF content showed the highest antioxidant activity in the composite. It is the first time that a simple combination of ChNF–CNF composites fabrication showed good mechanical properties and antioxidant activities. In this study, the reinforcement effect of the composite was addressed. The ChNF–CNF composite is promising for active food packaging application.


Author(s):  
Avilash Carpenter ◽  
M.K. Gupta ◽  
Neetesh Kumar Jain ◽  
Urvashi Sharma ◽  
Rahul Sisodiya

Aim: The main of the study is to formulate and develop orally disintegrating fast dissolving tablet of Metoclopramide hydrochloride. Material & Methods: Before formulation and development of selected drug, the standard curve in buffer was prepared and absorbance at selected maxima was taken. Then two different disintegrating agents were selected and drug was mixed with disintegrating agents in different ratio. Various Preformulation parameters and evaluation of tablet i.e. disintegration time, dissolution time, friability, hardness, thickness were measured by standard procedure. Result & Discussion: The angle of repose for all the batches prepared. The values were found to be in the range of 30.46 to 36.45, which indicates good flow property for the powder blend according to the USP. The bulk density and tapped density for all the batches varied from 0.49 to 0.54 g/mL and 0.66 to 0.73, respectively. Carr’s index values were found to be in the range of 23.33 to 25.88, which is satisfactory for the powders as well as implies that the blends have good compressibility. Hausner ratio values obtained were in the range of 1.22 to 1.36, which shows a passable flow property for the powder blend based on the USP. The results for tablet thickness and height for all batches was found to range from 4.45 to 4.72 mm and 3.67 to 3.69 mm, respectively. Hardness or breaking force of tablets for all batches was found to range from 32.8 to 36.2 N. Tablet formulations must show good mechanical strength with sufficient hardness in order to handle shipping and transportation. Friability values for all the formulations were found to be in the range of 0.22 % to 0.30 %. Conclusion: Orally disintegrating tablets were compressed in order to have sufficient mechanical strength and integrity to withstand handling, shipping and transportation. The formulation was shown to have a rapid disintegration time that complied with the USP (less than one minute). The data obtained from the stability studies indicated that the orally disintegrating mini-tablets of MTH were stable under different environmental storage conditions. Keywords: Formulation & Development, Fast Dissolving Tablet, Metoclopramide, Anti-Emetic Drug, Oral Disintegrating Tablet


2003 ◽  
Vol 766 ◽  
Author(s):  
Raymond N. Vrtis ◽  
Mark L. O'Neill ◽  
Jean L. Vincent ◽  
Aaron S. Lukas ◽  
Brian K. Peterson ◽  
...  

AbstractWe report on our work to develop a process for depositing nanoporous organosilicate (OSG) films via plasma enhanced chemical vapor deposition (PECVD). This approach entails codepositing an OSG material with a plasma polymerizable hydrocarbon, followed by thermal annealing of the material to remove the porogen, leaving an OSG matrix with nano-sized voids. The dielectric constant of the final film is controlled by varying the ratio of porogen precursor to OSG precursor in the delivery gas. Because of the need to maintain the mechanical strength of the final material, diethoxymethylsilane (DEMS) is utilized as the OSG precursor. Utilizing this route we are able to deposit films with a dielectric constant of 2.55 to 2.20 and hardness of 0.7 to 0.3 GPa, respectively.


Alloy Digest ◽  
2009 ◽  
Vol 58 (8) ◽  

Abstract DMV 59 is the material of choice for a wide variety of applications where significant corrosion resistance and high mechanical strength is necessary. This datasheet provides information on composition, physical properties, elasticity, and tensile properties as well as fracture toughness. It also includes information on high temperature performance and corrosion resistance as well as forming, heat treating, and joining. Filing Code: Ni-672. Producer or source: Mannesmann DMV Stainless USA Inc.


Alloy Digest ◽  
1993 ◽  
Vol 42 (2) ◽  

Abstract Durcomet 100 is an improved version of Alloy CD-4 MCu with better corrosion and wear resistance. The alloy is used in the annealed condition and possesses excellent corrosion resistance over a wide range of corrosion environments. Mechanical strength is also very high. This datasheet provides information on composition, physical properties, hardness, and tensile properties as well as fracture toughness. It also includes information on corrosion resistance as well as heat treating and joining. Filing Code: SS-540. Producer or source: Duriron Company Inc.


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