scholarly journals New diagnostic criteria for assessing homeostasis in patients with respiratory tuberculosis

2018 ◽  
Vol 20 (2) ◽  
pp. 10-15
Author(s):  
O N Brazhenko ◽  
N A Brazhenko ◽  
A I Loshakova ◽  
N V Tsygan ◽  
S G Zheleznyak
Keyword(s):  
Diagnostic Criteria ◽  
Clinical Work ◽  
The State ◽  
The Body ◽  
Activation Reaction ◽  
Medium Strength ◽  
General Adaptation ◽  
Pathogenetic Therapy ◽  
Qualitative Characteristics ◽  
Adaptive Reactions

The search for available informative criteria for diagnosing the state and dynamics of the homeostatic equilibrium of the organism, which began at the end of the XIXth century, continues to the present. Scientific research establishes the priorities for the study of homeostasis in the clinic and its control over the supra-segmental regulatory centers of the autonomic nervous system. The proposed functional, instrumental, immunological, biochemical and hormonal methods for evaluating it in phthisiology for various reasons, including economic ones, cannot be used fully. The modern clinic needs accessible and informative criteria for homeostasis. The theoretical basis for their development was the doctrine of the general adaptation syndrome, which revealed the reaction of «stress» to extreme irritants. The subsequent discovery of changes in the body’s homeostasis to the effect of strong, medium strength, and weak stimuli has made it possible to identify three more types of adaptation reactions: the training reaction, the activation reaction, and the re-activation reaction. At the Department of Phthisiopulmonology of the FirstSt. PetersburgStateMedicalUniversity named after Acad. I.P. Pavlov proposed and tested new diagnostic criteria for homeostasis. They were developed on the basis of quantitative and qualitative characteristics of the formed elements of peripheral blood. Among them, in addition to these types of adaptive reactions of the body, leukocyte- lymphocyte index, indices of monocytogram, degree of disturbance of homeostasis and types of reactivity of the organism were introduced. These criteria allowed us to determine not only the state of homeostatic equilibrium of the organism, but also to assess the depth of its disturbance and the types of reactivity of the organism. Their use in daily clinical work provides an opportunity to monitor the course of the disease and carry out a personified correction by means of pathogenetic therapy.

scholarly journals Dynamics of homeostasis and the outcome of sarcoidosis of the respiratory system in the treatment of corticosteroids

2018 ◽  
Vol 20 (3) ◽  
pp. 21-26
Author(s):  
A I Loshakova ◽  
N A Brazhenko ◽  
S G Zheleznyak ◽  
O N Brazhenko ◽  
N V Tsygan ◽  
...  
Keyword(s):  
Diagnostic Criteria ◽  
Respiratory System ◽  
White Blood Cells ◽  
The State ◽  
Medical Institutions ◽  
Proliferation And Differentiation ◽  
General Adaptation ◽  
Working Performance ◽  
Medical University ◽  
Adaptive Reactions

The outcome of sarcoidosis of the respiratory system is closely linked to the state of homeostasis and reactivity. Monitoring their status is possible through immunological, biochemical and hormonal studies. Within common medical institutions re-executing these studies is not always possible for a number of reasons. Therefore, the research for the availability and informative criteria of homeostasis and reactivity state was initiated at the end of XIXth century and continues until now. At the Department of Phthisiopulmonology of the First St.-Petersburg state medical University Academy I. P. Pavlov. University, new accessible and informative diagnostic criteria for estimation the state of homeostatic balance of the organism are developed. They are based on research of the general adaptation syndrome and the discovery of antistress types of adaptive reactions of the organism. In this regard, based on the leukogram evaluation following diagnostic criteria were developed and tested: leukocyte-lymphocytic index, types of adaptive reactions, entropy and redundancy of formed elements of white blood cells, extent of disturbance of homeostasis, indices of proliferation and differentiation of monocytes and reactivity types. Unfortunately, in the pulmonology clinics, they are used today only in single cases. The monitoring of homeostasis and reactivity indicators in patients with respiratory system sarcoidosis had a high working performance. It is established that in sarcoidosis the best treatment effect with corticosteroids with minimal residual changes of respiratory system took place in patients with the appropriate type of reactivity and normal range of other indicators. Pathological reactivity of an organism, especially hyporeactive and areactive types, are always accompanied by formation of pronounced residual sarcoidosis changes in the respiratory tract, which is the basis for the subsequent exacerbation (recurrence) of sarcoidosis.

scholarly journals Change in homeostasis of the body and the outcome of tuberculosis in the treatment of antituberculous medicines

2018 ◽  
Vol 20 (3) ◽  
pp. 95-99
Author(s):  
A I Loshakova ◽  
N V Tsygan ◽  
S G Zheleznyak ◽  
N A Brazhenko ◽  
O N Brazhenko
Keyword(s):  
The State ◽  
The Body ◽  
Physical Factors ◽  
Daily Work ◽  
Role Of The State ◽  
Proliferation And Differentiation ◽  
Fundamental Research ◽  
Clinical Conditions ◽  
Medical University ◽  
Adaptive Reactions

Fundamental research in the field of physiology revealed the important role of the state of homeostatic balance of the body in the emergence, development and outcome of human diseases, including granulomatous respiratory diseases- tuberculosis and sarcoidosis. To assess the homeostasis of the body in clinical conditions, various research methods are used - immunological, biochemical, hormonal and functional. However, in the daily work they can’t always be performed for technical and economic reasons. Proposed a new available diagnostics criterion of homeostasis based on the study of the quantitative and qualitative characteristics of the leukocytic formula of peripheral blood at the Department of videopornonoelia the First St. Petersburg state medical University Academy I. P. Pavlov. Among them types of adaptive reactions, leukocyte- lymphocytic index, entropy and redundancy of indicators of leukogram, monitorama blood, the degree of homeostasis and types of reactivity of an organism. During their approbation in the clinic high information content was revealed: more than 70% of the examined patients with tuberculosis of respiratory organs had defective types of adaptive reactions (intense), indices of proliferation and differentiation of monocytes were changed, and reactivity of the organism was characterized by pathological types (hyperreactive, paradoxical, hyporeactive and areactive). Treatment of patients with anti-tuberculosis drugs partially improved homeostasis, but its full recovery at the end of the main course of treatment did not occur. For better treatment in complex therapy, it is necessary to activate the body’s protective systems with the use of adaptogens (drugs, medicinal plants, physical factors: ultrasound, ultra-high-frequency inductothermy, alternating magnetic field on the regulatory centers of the suprasegmental apparatus of the autonomic nervous system). Monitoring of the state of homeostasis is most convenient to carry out using the proposed new available criteria for its evaluation.

The Vegetative Status Correction in the Patients with Chronic Dyscirculatory Encephalopathy on the Sanatorium Rehabilitation Stage

10.12737/5760 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 1-6
Author(s):  
Куликов ◽  
N. Kulikov ◽  
Череващенко ◽  
Lyubov Cherevashchenko ◽  
Череващенко ◽  
...  
Keyword(s):  
Laser Therapy ◽  
The State ◽  
The Body ◽  
Brain Diseases ◽  
Control Group ◽  
Autonomic Imbalance ◽  
Dyscirculatory Encephalopathy ◽  
Before And After ◽  
The Brain ◽  
Adaptive Reactions

Among vascular brain diseases a special place in its importance takes chronic cerebrovascular pathology in the form of dyscirculatory encephalopathy. The most frequently affected cerebral structures with discirculatory encephalopathy are those parts of the brain that are largely responsible for shaping over segmental vegetative disorders, which are characteristic of clinics chronic cerebrovascular insufficiency. The purpose of this work is to develop a new modern high technology of sanatorium rehabilitation of the patients with circulatory encephalopathy on stage I and to correct autonomic imbalance. The authors observed 60 patients who were divided into 2 groups. The control group received radon baths, the patients from the main group in addition to radon baths received laser therapy paravertebrally C1-Th3, according to scanning technique. In all patients before and after treatment the state of the autonomic nervous system studied. It was found that the initial manifestations of vascular encephalopathy accompanied by autonomic imbalance with a predominance of sympathetic tone, activation and inhibition effects of ergotrop activities segmental systems, primarily due to the parasympathetic division. The results of this study demonstrate feasibility of incorporating laser therapy in complex radon baths for rehabilitation of patients with circulatory encephalopathy autonomic imbalance. The findings suggest that improving the functional state mechanisms vegetative maintenance activities, which help to eliminate the state of surge and flow of adaptive reactions in the body.

La systémique: son apport à la sylviculture et son rapport au marché | Systemics: its contribution to silviculture and its connection to the market

2006 ◽  
Vol 157 (7) ◽  
pp. 283-286
Author(s):  
Guido Bernasconi
Keyword(s):  
Forest Management ◽  
Public Funding ◽  
Management Plan ◽  
Living System ◽  
The State ◽  
The Body ◽  
Systemic Approach ◽  
Forest Management Plan

The silvicultural principles of a forest management plan for Canton Neuchâtel reveals itself as steeped in a systemic approach that allows us to consider the forest as a truly living system. In this context, it seems judicious to the author to conceive of the body forest personnel as a group of responsible people who share certain common ethics and who, in their work, promote the emergence of collective services recognised as beneficial to the state and which would be supported by public funding for the good of the entire community.

A Litreary Review of Vishama Jwara and its principle of treatment

2016 ◽  
Vol 1 (2) ◽  
Author(s):  
Dr.Saurabh Parauha ◽  
Hullur M. A. ◽  
Prashanth A. S.
Keyword(s):  
High Temperature ◽  
Body Temperature ◽  
The State ◽  
The Body ◽  
Cardinal Symptoms

In Ayurveda, Jwara is not merely the concept of raised body temperature, but as is said in Charaka Samhita, 'Deha- Indriya- Manah- Santap' is the cardinal symptoms of Jwara. This can be defined as the state where the body, mind as well as sense oragans suffer due to the high temperature. Vishamajwara is a type of fever, which is described in all Ayurvedic texts. Charaka mentioned Vishamajwara and Chakrapani have commented on Vishamajwara as Bhutanubanda, Susruta affirmed that Aagantuchhanubhandohi praysho Vishamajware. Madhavakara has also recognised Vishamajwara as Bhutabhishangajanya (infected by microorganism). Vishamajwara is irregular (inconsistent) in it's Arambha (nature of onset commitment), Kriya (action production of symptoms) and Kala (time of appearance) and possesses Anushanga (persistence for long periods). The treatment of this disease depends upon Vegavastha and Avegavastha of Jwara. Various Shodhana and Shamana procedures are mentioned in classics to treat Visham Jwara.

scholarly journals Problems of Pathogenesis and Pathogenetic Therapy of COVID-19 from the Perspective of the General Theory of Pathological Systems (General Pathological Processes)

2021 ◽  
Vol 22 (14) ◽  
pp. 7582
Author(s):  
Evgenii Gusev ◽  
Alexey Sarapultsev ◽  
Desheng Hu ◽  
Valeriy Chereshnev
Keyword(s):  
Systemic Inflammation ◽  
Pathological Process ◽  
The State ◽  
The Other ◽  
Low Grade ◽  
Metabolic Dysfunction ◽  
The Metabolic Syndrome ◽  
Other Hand ◽  
Pathogenetic Therapy ◽  
Fundamental Medicine

The COVID-19 pandemic examines not only the state of actual health care but also the state of fundamental medicine in various countries. Pro-inflammatory processes extend far beyond the classical concepts of inflammation. They manifest themselves in a variety of ways, beginning with extreme physiology, then allostasis at low-grade inflammation, and finally the shockogenic phenomenon of “inflammatory systemic microcirculation”. The pathogenetic core of critical situations, including COVID-19, is this phenomenon. Microcirculatory abnormalities, on the other hand, lie at the heart of a specific type of general pathological process known as systemic inflammation (SI). Systemic inflammatory response, cytokine release, cytokine storm, and thrombo-inflammatory syndrome are all terms that refer to different aspects of SI. As a result, the metabolic syndrome model does not adequately reflect the pathophysiology of persistent low-grade systemic inflammation (ChSLGI). Diseases associated with ChSLGI, on the other hand, are risk factors for a severe COVID-19 course. The review examines the role of hypoxia, metabolic dysfunction, scavenger receptors, and pattern-recognition receptors, as well as the processes of the hemophagocytic syndrome, in the systemic alteration and development of SI in COVID-19.

scholarly journals Correlation of age, sex and season with the state of human decomposition as quantified by postmortem computed tomography

2021 ◽  
Author(s):  
Dominic L. C. Guebelin ◽  
Akos Dobay ◽  
Lars Ebert ◽  
Eva Betschart ◽  
Michael J. Thali ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Demographic Data ◽  
Sociodemographic Factors ◽  
The State ◽  
The Body ◽  
Seasonal Effects ◽  
Whole Body ◽  
Postmortem Computed Tomography ◽  
Whole Body Computed Tomography ◽  
Urban Study

AbstractDead bodies exhibit a variable range of changes with advancing decomposition. To quantify intracorporeal gas, the radiological alteration index (RAI) has been implemented in the assessment of postmortem whole-body computed tomography. We used this RAI as a proxy for the state of decomposition. This study aimed to (I) investigate the correlation between the state of decomposition and the season in which the body was discovered; and (II) evaluate the correlations between sociodemographic factors (age, sex) and the state of decomposition, by using the RAI as a proxy for the extent of decomposition. In a retrospective study, we analyzed demographic data from all autopsy reports from the Institute of Forensic Medicine of Zurich between January 2017 to July 2019 and evaluated the radiological alteration index from postmortem whole-body computed tomography for each case. The bodies of older males showed the highest RAI. Seasonal effects had no significant influence on the RAI in our urban study population with bodies mostly being discovered indoors. Autopsy reports contain valuable data that allow interpretation for reasons beyond forensic purposes, such as sociopolitical observations.

Gendered Secularization and the Body Policing of Muslim Women

2018 ◽  
Author(s):  
Raissa Killoran
Keyword(s):  
Muslim Women ◽  
The State ◽  
The Body ◽  
Religious Expression ◽  
Women's Bodies ◽  
Cultural Symbols ◽  
Religious Symbols ◽  
Female Bodies ◽  
The Many ◽  
A Site

The many usages of the term ‘secularism’ have generated an ambiguity in the word; as a political guise, it may be used to engender anti-religious fervor. Particularly in regards to veiling among female Muslim adherents, the attainment of a secular state and touting of the necessity of dismantling religious symbols have functioned as linguistic shields. By calling a “burka ban” necessary or even egalitarian secularization, legislators employ ‘secularization’ as jargon for political ends, enacting a stance of supremacy under the semblance of progress. Secularization has come to function as a political tool - in the name of it, governments may prescribe which cultural symbols are normative and which are of ‘other’ cultures or religious origins. As such, the identification of some religious symbols as foreign and others as normative is a usage of secularization for normalization of dominant religious expression. In this, there is an implicit neocolonialism; by imposing standards of cultural normalcy which are definitively nonMuslim, such policies attempt to divorce Muslims from Islam.  Further, I intend to investigate the gendered aspect of secularization politics. By critiquing clothing and body policing of women, I will demonstrate how secularization projects use the female body and dress as a site for display. By rendering the female physically emblematic of the honor and virtue of an ‘other’ culture, those enacting secularization norms target women’s bodies to act as visual exhibitions of the dominant culture’s hegemony. Here, we see gendered secularization at work - female bodies become controlled by the antireligious zeal of the state, while the state carries out this control on the predicate that it is the religious group enacting unjust control. As such, the policing of female Muslim bodies is symbolic of the policing of Islam as a whole; it acts as an illustration of an imposed, gendered secularization project.

Studies on Tapeworm Physiology

1949 ◽  
Vol 26 (1) ◽  
pp. 1-15
Author(s):  
J. D. SMYTH
Keyword(s):  
Bacterial Infections ◽  
Detrimental Effect ◽  
Horse Serum ◽  
Body Cavity ◽  
The Body ◽  
Nutrient Media ◽  
Medium Strength ◽  
By Products ◽  
Histochemical Examination

1. Plerocercoid larvae of the pseudophyllidean cestode Ligula intestinalis from the body cavity of roach, were cultured in vitro at 40°C. in a variety of saline and nutrient media. About 65% of such cultures were aseptic. 2. During cultivation, larvae produced acid by-products (unidentified) and the pH fell rapidly. 3. The presence of these acid by-products slowed down development, or, if present in sufficient quantity, caused death. 4. In order to obtain development in nutrient media in a period (3 days) comparable to that required in a bird (the normal host) it was necessary to renew the medium 24-hourly. 5. 6% of the eggs produced from a worm cultured in horse serum were fertile. Fertile eggs were never obtained from larvae cultured in any other media. 6. Certain bacterial infections had no apparent detrimental effect on development, but others were toxic. 7. Some larvae underwent development in non-nutrient medium (¾ strength Locke's solution). The exact conditions under which this occurred was not determined. 8. Fragments (3 cm. long), of larvae or larvae with either scolex or posterior half removed, underwent development to the stage of oviposition in nutrient media. 9. Histochemical examination revealed that the plerocercoid larvae were almost fat-free. During cultivation, very large quantities of cytoplasmic fat were produced the quantity being proportional to the duration of cultivation. Fat was produced even under starvation conditions (i.e. during cultivation in saline) and can be considered a metabolic by-product. 10. The fresh plerocercoid contained great quantities of glycogen in the parenchyma and muscle regions. After cultivation in nutrient or saline media, considerable quantities were still present.

Young Russians: are they prepared to cybernatization of their own body?

2021 ◽  
pp. 781-800
Author(s):  
M.V. Semina
Keyword(s):  
Cultural Differences ◽  
The State ◽  
The Body ◽  
Young Generation ◽  
State Technical ◽  
Technical University

The purpose of this paper is to acquaint readers with the research conducted by students and employees of the State Technical University N.E. Bauman, who reveals the current attitudes of young generation to the issue of cybernatization of their own body. Which part of the body they are ready to transform? How do they visualize this process? Will there be some age, gender, cultural, differences in relations to the parts of the body they want to change? Are there any specific features that distinguish Russians from others in the processes of body cybernatization? This is what this paper says.

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