scholarly journals Dr. Lloyd G. Smith - On five Cases of hydrocele in the Female. (British medic. Journ., 28 / VIII, 94, pp. 179-180). Five cases of dropsy of the labia majora

2020 ◽  
Vol 9 (6) ◽  
pp. 599-600
Author(s):  
M. Ginzburg
Keyword(s):  
Rare Disease ◽  
Inguinal Canal ◽  
Entire Length ◽  
Fetal Life ◽  
Lower Branch ◽  
The Third ◽  
Labia Majora

Hydrocele in large lips in women - very rare disease; it is often confused with a hernia. As is known, the peritoneal process descends along with the round ligaments along the inguinal canal in the third month of the fetal life of the embryo, the canal overgrowth occurs after the birth of the child. The lack of a canal along its entire length leads to a hernia, on the lower branch - hydrocele lab. pudend. major.

Anemia in Preterm Infants

1996 ◽  
Vol 17 (10) ◽  
pp. 370-370
Author(s):  
Philip Roth
Keyword(s):  
Preterm Infants ◽  
Plasma Volume ◽  
Hemoglobin Concentration ◽  
Fetal Life ◽  
Combined Effects ◽  
Third Trimester ◽  
The Third ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Preterm Newborns

During fetal life, hemoglobin concentration increases from a level of 9 g/dL at l0 weeks' to 14 to 15 g/dL at 22 to 24 weeks' gestation. By the middle of the third trimester, concentrations close to those observed at birth (16 to 17 g/dL) are reached, and little additional change occurs. As a result, cord hemoglobin concentrations in term and preterm newborns are very similar, with the possible exception of the most extremely preterm infants. Immediately after birth, the hemoglobin concentration begins to rise from the combined effects of placental transfusion and the postnatal readjustment of plasma volume. At approximately 8 to 12 hours of life, the hemoglobin plateaus at levels 1 to 2 g/dL above those observed at birth (about 18 g/dL).

Persistence and Utilization of Maternal Iron For Blood Formation During Infancy

PEDIATRICS ◽  
1956 ◽  
Vol 17 (1) ◽  
pp. 44-44
Keyword(s):  
Cell Volume ◽  
Red Cells ◽  
Fetal Life ◽  
Dietary Iron ◽  
Red Cell ◽  
The Third ◽  
Long Period ◽  
Blood Formation ◽  
Maternal Iron ◽  
Dietary Origin

During the course of investigations of maternal red cell volume, employing transfusions with radioactive iron, an opportunity was afforded to measure the persistence and utilization of iron transferred across the placenta to the infant. A wealth of fundamental data was obtained concerning the importance of iron obtained from the mother in hematopoiesis during infancy. As the donors' cells containing radioactive iron which were transfused during pregnancy were broken down, radioactive iron was released into the general supply of the mother and fetus. At birth the blood of each infant contained a measurable ratio of radioactive iron to packed red cells. The ratio of radioactive iron to hemoglobin and to hemoglobin iron could then be calculated. Further calculations gave information concerning the amounts of hemoglobin iron of transplacental and dietary origin. The results indicated that there was little or no utilization of dietary iron for hemoglobin formation by the infants until 3 to 4 months after birth. Incorporation of the radioactive iron obtained transplacentally into hemoglobin during the growth of the infant indicated that normal infants utilize iron obtained during fetal life throughout infancy. Data from infants followed for a long period suggest that after 3 to 4 months dietary iron continues to be added to transplacental iron for the production of hemoglobin and gradually begins to replace transplacental iron in hemoglobin formation during the third year.

Successful resection of a giant thoracic myxoid liposarcoma

2018 ◽  
Vol 26 (5) ◽  
pp. 410-412
Author(s):  
Wei Chieng Pui ◽  
Winnie Hui Yee Ling ◽  
Momin Najah ◽  
Sing Yang Soon
Keyword(s):  
Rare Disease ◽  
Myxoid Liposarcoma ◽  
Left Hemithorax ◽  
The Third

Primary liposarcoma is an extremely rare disease. We report a case of giant thoracic myxoid liposarcoma that occupied the whole left hemithorax and was successfully resected. We discuss the surgical considerations and difficulties encountered, and how we overcome these challenges. This is the third largest thoracic myxoid liposarcoma resection reported, weighing 4 kg.

Outcomes for children with cardiomyopathy awaiting transplantation

2000 ◽  
Vol 10 (4) ◽  
pp. 358-366 ◽  
Author(s):  
Lynne E. Nield ◽  
Brian W. McCrindle ◽  
Desmond J. Bohn ◽  
Lori J. West ◽  
Jhon G. Coles ◽  
...  
Keyword(s):  
Systolic Pressure ◽  
Restrictive Cardiomyopathy ◽  
Clinical State ◽  
Fetal Life ◽  
Historical Cohort ◽  
Ventricular Systolic Pressure ◽  
The Third ◽  
Significant Survival ◽  
Outcomes For Children ◽  
Ventricular Assistance

AbstractObjectiveTo determine factors associated with outcomes after listing for transplantation in children with cardiomyopathies.BackgroundChildhood cardiomyopathies form a heterogeneous group of diseases, and in many, the prognosis is poor, irrespective of the etiology. When profound heart failure develops, cardiac transplantation can be the only viable option for survival.MethodsWe included all children with cardiomyopathy listed for transplantation between 12/89 and 4/98 in this historical cohort study.ResultsWe listed 31 patients, 15 male and 16 female, 27 with dilated and 4 with restrictive cardiomyopathy, for transplantation. The median age at listing was 5.7 years, with a range from fetal life to 17.8 years. Transplantation was achieved in 23 (74%), with a median interval from listing of 54 days, and a range from zero to 11.4 years. Of the patients, 14 were transplanted within 30 days of listing. Five patients (16%) died before transplantation. Within the Canadian algorithm, one of these was in the third state, and four in the fourth state. One patient was removed from the list after 12 days, having recovered from myocarditis, and two remain waiting transplantation after intervals of 121 and 476 days, respectively. Patients who died were more likely to be female (5/5 vs. 11/26; p=0.04) and to have been in the third or fourth states at listing (5/5 vs. 15/26; p=0.04). The use of mechanical ventricular assistance, in 10 patients, was not a predictor of an adverse outcome. While not statistically significant, survival to transplantation was associated with treatment using inhibitors of angiotensin converting enzyme, less mitral regurgitation, a higher mean ejection fraction and cardiac index, and lower right ventricular systolic pressure.ConclusionsChildren with cardiomyopathy awaiting transplantation have a mortality of 16% related to their clinical state at the time of listing.

Slow, programmed maturation of the immunoglobulin HCDR3 repertoire during the third trimester of fetal life

Blood ◽  
2001 ◽  
Vol 98 (9) ◽  
pp. 2745-2751 ◽  
Author(s):  
Harry W. Schroeder ◽  
Liming Zhang ◽  
Joseph B. Philips
Keyword(s):  
Cell Activation ◽  
Length Distribution ◽  
Systemic Exposure ◽  
Antibody Repertoire ◽  
Fetal Life ◽  
B Cell Activation ◽  
Third Trimester ◽  
The Third ◽  
Developmental Progression ◽  
The Mean

Abstract The mean distribution of lengths in the third complementarity-determining region of the heavy chain (HCDR3) serves as a measure of the development of the antibody repertoire during ontogeny. To determine the timing and pattern of HCDR3 length maturation during the third trimester of pregnancy, the mean distribution of HCDR3 lengths among variable-diversity-joining-constant–μ (VDJCμ) transcripts from the cord blood was analyzed from 138 infants of 23 to 40 weeks' gestation, including 3 sets of twins, 2 of which were of dizygotic origin. HCDR3 maturation begins at the start of the third trimester; follows a slow, continuous expansion over a 5-month period; and is unaffected by race or sex. The range and mean distribution of lengths may vary in dizygotic twins, indicating individual rates of development. The mean HCDR3 length distribution in 10 premature infants with documented bacterial sepsis was then followed for 2 to 12 weeks after their first positive blood culture. HCDR3 spectrotype analysis demonstrated oligoclonal B-cell activation and expansion after sepsis, but maturation of the repertoire was not accelerated even by the systemic exposure to external antigen represented by bacteremia. Antibody repertoire development appears to be endogenously controlled and adheres to an individualized developmental progression that probably contributes to the relative immaturity of the neonatal immune response.

Torulosis of the Central Nervous System

1943 ◽  
Vol 89 (374) ◽  
pp. 42-51 ◽  
Author(s):  
Donald Blair
Keyword(s):  
United States ◽  
Central Nervous System ◽  
Nervous System ◽  
Rare Disease ◽  
Mental Hospital ◽  
The United States ◽  
Observation Unit ◽  
The Third ◽  
The World ◽  
The Central Nervous System

In March, 1939. there was admitted under my care at the St. Pancras Hospital Mental Observation Unit a case of torulosis of the nervous system. This is a very rare disease in this country and the present case is only the third recorded in British medical history (Greenfieldet al., 1938; Smith and Crawford, 1930), and the first one to have come under mental hospital supervision. Although such a rarity here, torulosis is more common in the United States, and cases have been reported from nearly every part of the world.

PALMAR DERMATOGLYPHICS IN MONGOLISM

PEDIATRICS ◽  
1950 ◽  
Vol 5 (2) ◽  
pp. 241-248
Author(s):  
HAROLD CUMMINS ◽  
CAROLYNN TALLEY ◽  
R. V. PLATOU
Keyword(s):  
Early Diagnosis ◽  
Fetal Life ◽  
Relative Ease ◽  
The Third ◽  
Embryologic Development

It has been demonstrated that characteristic dermatoglyphic changes rank high in frequency among the variable stigmata which go to make up the syndrome of mongolism. Though they are not diagnostic alone, it is believed that these objective, measurable and unchanging evidences of mongolism seen in hand prints should be helpful in establishing an early diagnosis. Positive dermatoglyphics rank high in frequency among stigmata reported in typical examples of mongolism by 82 physicians. The technic for preparing prints is a simple one which requires very little practice for perfection; interpretation based on the empiric but definite criteria defined can be accomplished with relative ease. A series of five prints are reproduced. These findings are in keeping with the suggestion that factors responsible for the occurrence of mongolism are operative prior to the third month of fetal life, and are consistent with known facts concerning embryologic development of epidermal ridges of the palms.

scholarly journals Fetal and Postnatal Growth and Body Composition at 6 Months of Age

2009 ◽  
Vol 94 (6) ◽  
pp. 2023-2030 ◽  
Author(s):  
Lamise Ay ◽  
Vera A. A. Van Houten ◽  
Eric A. P. Steegers ◽  
Albert Hofman ◽  
Jacqueline C. M. Witteman ◽  
...  
Keyword(s):  
Body Composition ◽  
Fat Mass ◽  
Lean Mass ◽  
Postnatal Growth ◽  
Growth Patterns ◽  
Fetal Life ◽  
Third Trimester ◽  
Fetal Ultrasound ◽  
The Third ◽  
Catch Up

Abstract Objectives: The objectives of the study was to examine which parental, fetal, and postnatal characteristics are associated with fat and lean mass at the age of 6 months and examine the effect of growth (catch-down, catch-up) in fetal life and early infancy on fat and lean mass. Design: This study was embedded in the Generation R Study, a prospective cohort study from early fetal life onward. Body composition was measured by dual-energy X-ray absorptiometry in 252 infants at 6 months. Parental, fetal, and postnatal data were collected by physical and fetal ultrasound examinations and questionnaires. Results: Children with fetal catch-up in weight (gain in weight sd score >0.67) in the second trimester tended to have a higher fat mass percentage [FM(%)] at 6 months of age, whereas children with fetal catch-down in weight had a lower FM(%) compared with nonchangers. In the third trimester, both catch-up and catch-down in weight were associated with an increase in FM(%) at 6 months. Children with catch-down in the third trimester had a greater risk for postnatal catch-up in weight greater than 0.67 sd score. Birth weight and weight at 6 wk were positively associated with fat mass at 6 months. Postnatal catch-up in weight within 6 wk after birth had the highest association with total and truncal FM(%) at 6 months. Total and truncal FM were higher in girls. Conclusion: Catch-down in weight in the third trimester was strongly associated with postnatal catch-up within 6 wk after birth, and both were associated with an increase in fat mass at the age of 6 months. Our study shows that fetal as well as postnatal growth patterns are associated with body composition in early childhood.

scholarly journals Inguinal canal angioleiomyoma: case report of a rare disease entity within inguinal canal

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Jianwen Liu ◽  
Rockson Wei ◽  
Xuefei Yang ◽  
Xinping Shen ◽  
Jing Guan ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Disease ◽  
Inguinal Canal ◽  
Disease Entity

Thrombocytopenia: First Symptom in a Patient with Dyskeratosis Congenita

PEDIATRICS ◽  
1981 ◽  
Vol 67 (6) ◽  
pp. 898-903
Author(s):  
Kris De Boeck ◽  
H. Degreef ◽  
R. Verwilghen ◽  
L. Corbeel ◽  
Maria Casteels-Van Daele
Keyword(s):  
Aplastic Anemia ◽  
Rare Disease ◽  
Clinical Course ◽  
Skin Pigmentation ◽  
Hereditary Disease ◽  
Dyskeratosis Congenita ◽  
Nail Dystrophy ◽  
The Third ◽  
Fanconi's Anemia ◽  
Fanconi’S Anemia

A case of dyskeratosis congenita is reported. This rare hereditary disease usually has the following progression: ectodermal dystrophy (reticular skin pigmentation, nail dystrophy, leukokeratosis of mucosal membranes), appearing in the first decade, followed in about 50% of these patients by a hematopoietic disorder resembling Fanconi's anemia, usually developing in the second or third decade. Carcinomas may occur in leukokeratotic areas in the third, fourth, or fifth decade. This patient's clinical course is interesting because the thrombocytopenia developed as an isolated symptom at the age of 5 years and preceded the skin anomalies by three years. The diagnosis of dyskeratosis congenita was made only after an evolution of five years. The diagnosis of dyskeratosis congenita—although it is a rare disease—should be considered in every child first seen with aplastic anemia or thrombocytopenia.

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