scholarly journals Fetal and Postnatal Growth and Body Composition at 6 Months of Age

2009 ◽  
Vol 94 (6) ◽  
pp. 2023-2030 ◽  
Author(s):  
Lamise Ay ◽  
Vera A. A. Van Houten ◽  
Eric A. P. Steegers ◽  
Albert Hofman ◽  
Jacqueline C. M. Witteman ◽  
...  
Keyword(s):  
Body Composition ◽  
Fat Mass ◽  
Lean Mass ◽  
Postnatal Growth ◽  
Growth Patterns ◽  
Fetal Life ◽  
Third Trimester ◽  
Fetal Ultrasound ◽  
The Third ◽  
Catch Up

Abstract Objectives: The objectives of the study was to examine which parental, fetal, and postnatal characteristics are associated with fat and lean mass at the age of 6 months and examine the effect of growth (catch-down, catch-up) in fetal life and early infancy on fat and lean mass. Design: This study was embedded in the Generation R Study, a prospective cohort study from early fetal life onward. Body composition was measured by dual-energy X-ray absorptiometry in 252 infants at 6 months. Parental, fetal, and postnatal data were collected by physical and fetal ultrasound examinations and questionnaires. Results: Children with fetal catch-up in weight (gain in weight sd score >0.67) in the second trimester tended to have a higher fat mass percentage [FM(%)] at 6 months of age, whereas children with fetal catch-down in weight had a lower FM(%) compared with nonchangers. In the third trimester, both catch-up and catch-down in weight were associated with an increase in FM(%) at 6 months. Children with catch-down in the third trimester had a greater risk for postnatal catch-up in weight greater than 0.67 sd score. Birth weight and weight at 6 wk were positively associated with fat mass at 6 months. Postnatal catch-up in weight within 6 wk after birth had the highest association with total and truncal FM(%) at 6 months. Total and truncal FM were higher in girls. Conclusion: Catch-down in weight in the third trimester was strongly associated with postnatal catch-up within 6 wk after birth, and both were associated with an increase in fat mass at the age of 6 months. Our study shows that fetal as well as postnatal growth patterns are associated with body composition in early childhood.

scholarly journals Dietary modulation of body composition and insulin sensitivity during catch-up growth in rats: effects of oils rich in n-6 or n-3 PUFA

2011 ◽  
Vol 105 (12) ◽  
pp. 1750-1763 ◽  
Author(s):  
Gayathri Yepuri ◽  
Helena Marcelino ◽  
Yasaman Shahkhalili ◽  
Olivier Aprikian ◽  
Katherine Macé ◽  
...  
Keyword(s):  
Body Composition ◽  
Insulin Sensitivity ◽  
Fat Mass ◽  
Lean Mass ◽  
Quadratic Model ◽  
High Fat ◽  
High Fat Diets ◽  
Catch Up ◽  
Fat Diets ◽  
The Impact

The present study investigates whether excessive fat accumulation and hyperinsulinaemia during catch-up growth on high-fat diets are altered by n-6 and n-3 PUFA derived from oils rich in either linoleic acid (LA), α-linolenic acid (ALA), arachidonic acid (AA) or DHA. It has been shown that, compared with food-restricted rats refed a high-fat (lard) diet low in PUFA, those refed isoenergetically on diets enriched in LA or ALA, independently of the n-6:n-3 ratio, show improved insulin sensitivity, lower fat mass and higher lean mass, the magnitude of which is related to the proportion of total PUFA precursors (LA+ALA) consumed. These relationships are best fitted by quadratic regression models (r2>0·8, P < 0·001), with threshold values for an impact on body composition corresponding to PUFA precursors contributing 25–30 % of energy intake. Isoenergetic refeeding on high-fat diets enriched in AA or DHA also led to improved body composition, with increases in lean mass as predicted by the quadratic model for PUFA precursors, but decreases in fat mass, which are disproportionately greater than predicted values; insulin sensitivity, however, was not improved. These findings pertaining to the impact of dietary intake of PUFA precursors (LA and ALA) and their elongated–desaturated products (AA and DHA), on body composition and insulin sensitivity, provide important insights into the search for diets aimed at counteracting the pathophysiological consequences of catch-up growth. In particular, diets enriched in essential fatty acids (LA and/or ALA) markedly improve insulin sensitivity and composition of weight regained, independently of the n-6:n-3 fatty acid ratio.

Body composition in preterm infants with intrauterine growth restriction: a cohort study

2018 ◽  
Vol 46 (7) ◽  
pp. 804-810 ◽  
Author(s):  
Letícia Duarte Villela ◽  
Maria Dalva Barbosa Baker Méio ◽  
Saint Clair S. Gomes Junior ◽  
Andrea Dunshee de Abranches ◽  
Fernanda Valente Mendes Soares ◽  
...  
Keyword(s):  
Body Composition ◽  
Cohort Study ◽  
Preterm Infants ◽  
Fat Mass ◽  
Lean Mass ◽  
Gestational Age ◽  
Growth Patterns ◽  
Very Preterm Infants ◽  
Air Displacement Plethysmography ◽  
Appropriate For Gestational Age

Abstract Aims: The comparison of body composition parameters between the small for gestational age (SGA) and appropriate for gestational age (AGA) at term, 1, 3 and 5 months corrected ages in very preterm infants. Methods: This cohort study included 92 preterm infants at term age, younger than 32 weeks or <1500 g, classified in two groups: SGA and AGA. Anthropometry and body composition, estimated by air displacement plethysmography, were evaluated at the corrected ages: term and 1, 3, and 5 months. We used the lean mass/fat mass index (LM/FM) at each time point and the weight, length and head circumference SDS gain between the time points. Results: At term age, the SGA preterm infants had less lean mass (g), fat mass (g) and percent fat mass but a greater LM/FM index than AGA infants (P<0.001). At 1 month corrected age the LM/FM index and percent fat mass between the groups became similar. Lower lean mass persisted up to 3 months in the SGA group [4004 g (3256–4595) vs. 4432 g (3190–6246), P<0.001]. During the first month corrected age, the weight SDS gain was higher in SGA preterm infants when compared to AGA preterm infants. However, the SGA preterm infants remained lighter, shorter and with smaller head circumferences than the AGA preterm infants until 3 months of corrected age. Conclusions: The greater lean tissue deficits and an earlier “catch-up” in fat in the SGA group can reflect growth patterns variability since the early life.

scholarly journals Impact of changes in maternal body composition on birth weight and neonatal fat mass in dichorionic twin pregnancies

2018 ◽  
Vol 108 (4) ◽  
pp. 716-721 ◽  
Author(s):  
Manisha Gandhi ◽  
Rajshi Gandhi ◽  
Lauren M Mack ◽  
Roman Shypailo ◽  
Anne L Adolph ◽  
...  
Keyword(s):  
Body Composition ◽  
Birth Weight ◽  
Fat Mass ◽  
Fat Free Mass ◽  
Birth Length ◽  
Third Trimester ◽  
Maternal Body ◽  
The Third ◽  
The Impact ◽  
Twin Pregnancies

AbstractBackgroundAlthough the impact of gestational weight gain (GWG) on birth weight in twin pregnancies has been demonstrated, the specific components of GWG have not been delineated for twin gestations. Fetal body composition has been shown to be modifiable in singleton gestations based on nutritional intervention strategies and may prove to have similar modifications in twin gestations.ObjectiveWe aimed to determine the relation of maternal body composition changes to birth weight, birth length, and neonatal fat mass (FM) in dichorionic-diamniotic twin pregnancies.DesignThis is a prospective study of 20 women with twin gestations. Comparisons were made between body composition variables during each trimester and for the entire pregnancy and compared with the outcomes of birth weight, neonatal fat percentage, and birth length.ResultsGWG within or above compared with below the IOM recommendations was associated with higher birth weights (P = 0.03, P = 0.04, respectively), but also with higher postpartum weight retention (P = 0.001). Total maternal protein gain over the pregnancy was positively associated with birth weight (P = 0.03). Changes in maternal fat-free mass (FFM), total body water (TBW), and FM from the first to the third trimester were not associated with either birth weight or neonatal FM percentage. However, maternal FM change from the second to the third trimester was significantly correlated to neonatal FM percentage (P = 0.02). Third trimester GWG and total protein gain were positively correlated with neonatal birth length (P = 0.02 and 0.03, respectively). Maternal FFM over all 3 trimesters showed a positive relation with neonatal birth length (P = 0.01).ConclusionsSignificant increases in maternal protein are associated with greater birth weight and neonatal birth length. Protein accretion, in contrast to TBW and FM gains, may be the most critical component of maternal GWG in dichorionic twin gestations.

scholarly journals Part of the Fat Component in the Structure of Gestational Weight Gain

2018 ◽  
Vol 25 (1) ◽  
Author(s):  
Svitlana Ostafiichuk
Keyword(s):  
Body Composition ◽  
Weight Gain ◽  
Pregnant Women ◽  
Gestational Weight Gain ◽  
Fat Mass ◽  
First Trimester ◽  
The Body ◽  
Third Trimester ◽  
Gestational Weight ◽  
The Third

Gestational weight gain (GWG), which is more or less of the recommended guidelines, has serious short- and long-term negative consequences for the health of the mother and children. Determining the dynamics of body composition during pregnancy is important for full antenatal care in order to prevent pathological weight gain and prevention of gestational complications.Objective: Our goal was to determine the proportion of fat component in the structure of GWG in women with normal body weight before pregnancy. Design: 153 pregnant women aged 18-43 years with normal pre-pregnancy body mass index (pBMI) were examined. BMI was calculated by using the standard formula of person’s weight in kilograms divided by the square of his height in meters (kg/m2). Total weight gain was calculated by subtracting the pre-pregnancy weight from the last measured weight before delivery. The body composition (fat mass (FM), fat-free mass (FFM), and the percentage of fat mass (%FM)) was calculated on the basis of bioelectrical impedance analysis (BIA) using the ‘DIAMANT-AIST’ analyzer (St. Petersburg). Statistical analyses were carried out using Statistical program "Statistica 5.5".Results: It has been established that in women of normal weight before pregnancy, GWG was directly proportional to an increase in the fraction of FM (r=0.87; p<0.001). In pregnant with the recommended GWG, FM increased monotonous in the first and second trimesters and subsequently stabilized. In patients with insufficient GWG, fat component increased similarly (p>0.05), however, it was accompanied by low growth of the FFM, especially in the third trimester (p<0.05). Pregnant women with excessive GWG were more likely to gain weight in the first trimester mainly due to the accumulation of FM (p<0.05), and this tendency remained until delivery r=0.99 (p<0.01).Conclusion: In women with normal GWG there is a monotonous increase in fat component in the first and second trimesters, and subsequently stabilized, which promotes adequate weight reduction after childbirth. In patients with high GWG, the excessive increase in the proportion of FM and, consequently, a rapid increase in weight in the first trimester of pregnancy, initiates further accumulation of adipose tissue and slows down its reduction in the postpartum period. In pregnant women with low weight gain there is adequate increase of FM but an insufficient increase of FFM, especially in the third trimester, which leads to the development of placental hypoplasia and small-for-gestational age.

scholarly journals Body composition in childhood: effects of normal growth and disease

2003 ◽  
Vol 62 (2) ◽  
pp. 521-528 ◽  
Author(s):  
J. C. K. Wells
Keyword(s):  
Body Composition ◽  
Childhood Obesity ◽  
Fat Mass ◽  
Lean Mass ◽  
Normal Weight ◽  
Fat Free Mass ◽  
General Interest ◽  
Childhood And Adolescence ◽  
Adult Disease ◽  
Increased Risk

Body composition in children is of increasing interest within the contexts of childhood obesity, clinical management of patients and nutritional programming as a pathway to adult disease. Energy imbalance appears to be common in many disease states; however, body composition is not routinely measured in patients. Traditionally, clinical interest has focused on growth or nutritional status, whereas more recent studies have quantified fat mass and lean mass. The human body changes in proportions and chemical composition during childhood and adolescence. Most of the weight gain comprises lean mass rather than fat. In general, interest has focused on percentage fat, and less attention has been paid to the way in which lean mass varies within and between individuals. In the general population secular trends in BMI have been widely reported, indicating increasing levels of childhood obesity, which have been linked to reduced physical activity. However, lower activity levels may potentially lead not only to increased fatness, but also to reduced lean mass. This issue merits further investigation. Diseases have multiple effects on body composition and may influence fat-free mass and/or fat mass. In some diseases both components change in the same direction, whereas in other diseases, the changes are contradictory and may be concealed by relatively normal weight. Improved techniques are required for clinical evaluations. Both higher fatness and reduced lean mass may represent pathways to an increased risk of adult disease.

Abstract 17105: Is There a Difference in Lean and Fat Mass in HF Patients Based on NYHA Classifications (I-II versus III-IV)?

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_1) ◽  
Author(s):  
Christine Haedtke ◽  
Debra K Moser ◽  
Susan J Pressler ◽  
Terry Lennie
Keyword(s):  
Body Composition ◽  
Fat Mass ◽  
Lean Mass ◽  
Nyha Class ◽  
Class I ◽  
Unexpected Finding ◽  
Class Iii ◽  
Medication Regimen ◽  
Cross Sectional ◽  
Nyha Classification

Introduction: As NYHA Class increases from I (ordinary physical activity does not cause undue fatigue), to Class IV (Symptoms are present while at rest) physical limitations become severe. It has previously been shown that HF patients have increased fat within the muscle thus decreasing exercise performance and tolerance. It is unclear if all NYHA classes are similarly affected. Hypothesis: HF patients with NYHA class III-IV will have more fat and less lean mass than those with NYHA class I-II. Methods: Secondary data analysis using cross sectional data from N=253. The parent study was a multicenter study about nutrition and body composition among patients with HF (preserved or reduced, and NYHA classification I-IV) who had been on a stable medication regimen, able to participate in dual-energy X-ray absorptiometry scan and/or BodPod body composition measures, able to read and speak English, and had no cognitive impairment. Women and men were analyzed separately due to known differences in fat and lean mass. Results: Table 1: Sample characteristic’s Testing the hypothesis using 2-way ANOVA and comparing the percentage of body weight that is lean and fat mass in NYHA class I-II vs III-IV found the interaction of gender and NYHA was not significant in either % lean or %fat (p=0.221, 0.190 respectively). NYHA class by itself was not significant (p=0.067) in %lean but was significant in %fat (p=0.046). Gender was significant in both %lean and %fat with men having 9.6% less fat (1.139 SE) and 9.8% more lean mass (1.066 SE) (p≤0.001). NYHA class III-IV had 2.3% (1.139 SE) more fat than those in NYHA class I-II. The R squared was 0.265 and adjusted R squared was 0.256. Conclusions: Part of our hypothesis was correct in that NYHA class III-IV had more fat mass than those in class I-II, but no difference was found in lean. This is an unexpected finding as healthy people gain fat mass while losing lean mass as they age. Additional studies are needed to further examine this result.

Anemia in Preterm Infants

1996 ◽  
Vol 17 (10) ◽  
pp. 370-370
Author(s):  
Philip Roth
Keyword(s):  
Preterm Infants ◽  
Plasma Volume ◽  
Hemoglobin Concentration ◽  
Fetal Life ◽  
Combined Effects ◽  
Third Trimester ◽  
The Third ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Preterm Newborns

During fetal life, hemoglobin concentration increases from a level of 9 g/dL at l0 weeks' to 14 to 15 g/dL at 22 to 24 weeks' gestation. By the middle of the third trimester, concentrations close to those observed at birth (16 to 17 g/dL) are reached, and little additional change occurs. As a result, cord hemoglobin concentrations in term and preterm newborns are very similar, with the possible exception of the most extremely preterm infants. Immediately after birth, the hemoglobin concentration begins to rise from the combined effects of placental transfusion and the postnatal readjustment of plasma volume. At approximately 8 to 12 hours of life, the hemoglobin plateaus at levels 1 to 2 g/dL above those observed at birth (about 18 g/dL).

scholarly journals Longitudinal changes in body composition and waist circumference by self-reported levels of physical activity in leisure among adolescents: the Tromsø study, Fit Futures

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Nils Abel Aars ◽  
Bjarne K. Jacobsen ◽  
Bente Morseth ◽  
Nina Emaus ◽  
Sameline Grimsgaard
Keyword(s):  
Physical Activity ◽  
Body Composition ◽  
Waist Circumference ◽  
Fat Mass ◽  
Lean Mass ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
First Year ◽  
Fat Mass Index

Abstract Background It is not clear how physical activity affects body composition in adolescents. Physical activity levels are often reduced during this period, and the relative proportion of body fat mass and lean mass undergo natural changes in growing adolescents. We aimed to examine whether self-reported physical activity in leisure time at baseline or change in activity during follow-up affect changes in four measures of body composition; body mass index (kg/m2), waist circumference, fat mass index (fat mass in kg/m2) and lean mass index (lean mass in kg/m2). Methods We used data from the Tromsø Study Fit Futures, which invited all first year students in upper secondary high school in two municipalities in northern Norway in 2010–2011. They were reexamined in 2012–2013. Longitudinal data was available for 292 boys and 354 girls. We used multiple linear regression analyses to assess whether self-reported level of physical activity in leisure time at baseline predicted changes in body composition, and analysis of covariance to assess the effects of change in level of activity during follow-up on change in body composition. All analyses were performed sex-specific, and a p-value of < 0.05 was considered statistically significant. Results There were no associations between self-reported leisure time physical activity in the first year of upper secondary high school and changes in any of the considered measure of body composition after 2 years of follow up, with the exception of waist circumference in boys (p = 0.05). In boys, change in fat mass index differed significantly between groups of activity change (p < 0.01), with boys adopting activity or remaining physically active having less increase in fat mass index than the consistently inactive. In girls, change in lean mass index differed significantly between groups of activity change (p = 0.04), with girls adopting physical activity having the highest increase. Conclusions Self-reported leisure time physical activity does not predict changes in body composition in adolescents after 2 years of follow up. Change in the level of physical activity is associated with change in fat mass index in boys and lean mass index in girls.

scholarly journals Body weight at 10 years of age and change in body composition between 8 and 10 years of age were related to survival in a longitudinal study of 39 Labrador retriever dogs

2019 ◽  
Vol 61 (1) ◽  
Author(s):  
Johanna Christina Penell ◽  
David Mark Morgan ◽  
Penny Watson ◽  
Stuart Carmichael ◽  
Vicki Jean Adams
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
End Of Life ◽  
Fat Mass ◽  
Lean Mass ◽  
Coat Colour ◽  
Overweight And Obesity ◽  
Time Varying ◽  
Cohort Study Design ◽  
Changes Over Time

Abstract Background Overweight and obesity have been adversely associated with longevity in dogs but there is scarce knowledge on the relation between body composition and lifespan. We aimed to investigate the effects of body composition, and within-dog changes over time, on survival in adult Labradors using a prospective cohort study design. The dogs had a median age of 6.5 years at study start and were kept in similar housing and management conditions throughout. The effects of the various predictors, including the effect of individual monthly-recorded change in body weight as a time varying covariate, were evaluated using survival analysis. Results All dogs were followed to end-of-life; median age at end-of-life was 14.0 years. Body composition was measured annually with dual-energy x-ray absorptiometer (DEXA) scans between 6.2 and 17.0  years. All 39 dogs had DEXA recorded at 8, 9 and 10 years of age. During the study the mean (± SD) percent of fat (PF) and lean mass (PL) was 32.8 (± 5.6) and 64.2 (± 5.5) %, respectively, with a mean lean:fat ratio (LFR) of 2.1 (± 0.6); body weight (BW) varied from 17.5 to 44.0 kg with a mean BW change of 9.9 kg (± 3.0). There was increased hazard of dying for every kg increase in BW at 10 years of age; for each additional kg of BW at 10 years, dogs had a 19% higher hazard (HR = 1.19, P = 0.004). For the change in both lean mass (LM) and LFR variables, it was protective to have a higher lean and/or lower fat mass (FM) at 10 years of age compared to 8 years of age, although the HR for change in LM was very close to 1.0. For age at study start, older dogs had an increased hazard. There was no observed effect for the potential confounders sex, coat colour and height at shoulders, or of the time-varying covariate. Conclusions These results suggest that even rather late-life control efforts on body weight and the relationship between lean and fat mass may influence survival in dogs. Such “windows of opportunity” can be used to develop healthcare strategies that would help promote an increased healthspan in dogs.

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