On the question of amygdala sepsis

1930 ◽  
Vol 26 (10) ◽  
pp. 1055-1056
Author(s):  
B. Goland
Keyword(s):  
Mucous Membrane ◽  
High Fever ◽  
Recurrent Tonsillitis ◽  
Lower Jaw ◽  
Long Time ◽  
Inflammatory Processes

Abstracts. Laryngology. On the question of amygdala sepsis. Prof. Uffenоrdе. (Deutsche med. Woch., 1929, No. 19, S. 775) gives 4 cases of sepsis after inflammatory processes in the pharynx. 1st case. An 18-year-old girl who had suffered from frequent recurrent tonsillitis for a long time, 2 days after a new exacerbation, a swelling formed on the left side of the neck, with difficulty in the mobility of the lower jaw, chills and high fever. Objective examination revealed a thickening of the left tonsilla without plaque (the peritonsillar area was unchanged), swelling and redness of the left side of the epiglottis, the left scooped-epiglottis fold and the mucous membrane covering the left scoop.

scholarly journals Micronuclei in blood lumphocytes of existing and former coal miners: evaluation of the effect of anthracosilicosis

2019 ◽  
Vol 17 (4) ◽  
pp. 57-64
Author(s):  
Vladimir G. Druzhinin ◽  
Svetlana V. Apalko ◽  
Elizaveta D. Baranova ◽  
Valentin P. Volobaev ◽  
Tatiana Yu. Drobchik ◽  
...  
Keyword(s):  
Coal Dust ◽  
Additional Contribution ◽  
Coal Miners ◽  
Genotoxic Effects ◽  
The Status ◽  
Long Time ◽  
Inflammatory Processes ◽  
Simultaneous Decrease ◽  
Genotoxic Risk ◽  
Cytogenetic Parameters

Background. The purpose of this study was to investigate the genotoxic risk in anthracosilicosis patients and in those with occupational exposure to coal dust. Materials and methods. We studied micronuclei (MN) and other cytogenetic lesions in blood lymphocytes in three groups of men comparable in age: 74 coal miners suffering from anthracosilicosis (AS), 41 healthy miners, and 70 control donors. Results. A significant increase in the frequency of MN was revealed with a simultaneous decrease in proliferative activity in samples of healthy and sick miners compared with the control. The level of MN in the lymphocytes of patients with AS significantly exceeded the corresponding indicator in the sample of healthy miners (1.22 0.05% versus 1.03 0.07%; p 0.01). The age of the subjects and the status of smoking did not have a significant effect on the frequency of cytogenetic parameters. Conclusion. AS in miners makes an additional contribution to the formation of DNA damage in lymphocytes. This contribution is probably due to oxidative stress accompanying inflammatory processes in pulmonary fibrosis. The results of the study also indicate the absence of differences in the frequency of MN when comparing subgroups of current and former miners. This means that the genotoxic effects in the lymphocytes of miners are able to persist for a long time after the termination of exposure by adverse factors in coal mining.

scholarly journals ECOLOGICAL FEATURES OF MICROBIOCENOSIS OF THE SKIN OF MAMMARY GLANDS AND VAGINA IN PREGNANT WOMEN WITH THREAT OF PRETERM LABOR

2017 ◽  
Author(s):  
V. Ya. Ivankiv ◽  
I. M. Malanchyn ◽  
N. I. Tkachuk
Keyword(s):  
Pregnant Women ◽  
Mucous Membrane ◽  
Preterm Labour ◽  
Mammary Glands ◽  
Physiological Solution ◽  
Adequate Treatment ◽  
Ecological Features ◽  
Mother And Child ◽  
Sterile Medium ◽  
Inflammatory Processes

Background. The threat of preterm birth is one of the most topical issues in the world medicine. According to the statistics, from 12-13 to 25-35 % of all pregnancies end prematurely. One of the causes of preterm labour is chronic inflammatory processes of female genital organs and disorder of microbiocenosis. Timely diagnosis and adequate treatment will reduce the risk of premature labour and avoid perinatal loss.Objective. We examined and analysed the microflora of the skin of mammary glands and mucous membrane of vagina in healthy pregnant women and patients with threat of preterm labour.Materials and methods. The examination of the pregnant was conducted at the TRMPC “Mother and Child” in several stages. First of all, we rinsed the skin of mammary glands and smeared from mucous membrane the posterior vault of vagina with sterile swabs pre-moistened in physiological solution. After that, the tampons were placed in sterile tubes and delivered to laboratory. Sowing was carried out on Petri dishes with sterile medium: ZHSA, bloods MPA, Endo, Saburo, thioglycolic medium.Conclusions. As a result of the research we found saprophytic Gram-positive and Gram-negative microorganisms (in women with a physiological course of pregnancy). In pregnant women with preterm labour, there was the increase in the number of St. haemolyticus from 13% to 87%, appearance of representatives of pathogenic flora – St. aureus (in 20%).

The Process of Acute and Chronic Inflammation

2020 ◽  
pp. 1-23
Author(s):  
Sedat Demir
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Aging Process ◽  
Inflammatory Process ◽  
Ischemic Heart ◽  
Clinical Markers ◽  
Rheumatologic Diseases ◽  
Long Time ◽  
Inflammatory Processes ◽  
Acute And Chronic Inflammation

Inflammation is a physiopathological process that has been known for a long time but its relation with acute and chronic diseases and its role in the development of disease is becoming better understood. Diabetes, hypertension, ischemic heart disease, various organ cancers, rheumatologic diseases, the most common diseases of the liver, lungs and kidneys are either closely related to inflammatory processes or are caused by direct inflammatory processes. In one aspect, the aging process is a progressive inflammatory process. The understanding of what inflammation is and the mechanisms by which the inflammation occurs in the organism and by accurately identifying and following the clinical markers that show the course of inflammation. In this section, basic issues related to inflammation is examined.

scholarly journals Application of multi-layer chitosan-based wound dressings in dentistry

2020 ◽  
Vol 27 (1) ◽  
pp. 27-39
Author(s):  
Alexandr S. Gumenyuk ◽  
Denis I. Ushmarov ◽  
Sergey E. Gumenyuk ◽  
Tatyana V. Gaivoronskaya ◽  
Alexandr S. Sotnichenko ◽  
...  
Keyword(s):  
Blood Clot ◽  
Wound Dressings ◽  
Free Access ◽  
High Adhesion ◽  
Purulent Wounds ◽  
Long Time ◽  
Inflammatory Processes ◽  
Access To Water ◽  
Series Of Experiments ◽  
Pathological Focus

Aim. To experimentally evaluate the efficacy of multi-layer chitosan-based wound dressings developed for dental purposes.Materials and Methods. Over the period from 2018 to 2019, an experimental study was conducted to evaluate the efficacy of multi-layer chitosan-based wound dressings developed for dental practice. Two types of dressings (No. 1c and 2c), the central part of which was modified with the introduction of a 10% iodopyron solution, were compared with the widely-used wound dressings Alvostaz (NKF Omega-Dent LLC, Russia) and Gelatamp (Roeko, Germany). The work involved 26 male Chinchilla rabbits, ten months old and weighing 2500 (±50) g. Evaluation of the efficacy of the wound dressings under study was carried by modelling the conditions of both aseptic and purulent-inflammatory processes (a total of 8 series of experiments). In experiments modelling the purulent-inflammatory process, a Ps. aeruginosa bacterial culture at a concentration of 109 CFU/ml was introduced into the alveolar socket after tooth extraction, 3 days before the application of a wound dressing sample. The dressings under study were applied on the wound for the period of 7 days. During the observation postoperative period, the animals were provided with free access to water and food. The sampling of the material for the study was carried out in the operating room on day 7.Results. According to the experimental results, chitosan-based wound dressings (No. 2c in particular) demonstrated high efficacy in experiments on animals (rabbits). The developed wound dressings perform mechanical protection and exhibit fuse effects, as well as are characterized by biodegradability and the ability to deliver medical agents contained therein to the damaged tissue.Conclusion. The proposed chitosan-based wound dressings showed sufficient efficiency on the modelled wound process in the alveolar socket of an extracted tooth. Dressing No. 2c was recognised to be optimal for infected and purulent wounds. This dressing has a dense outer layer, which structure retains frame functions for a long time, thus providing proper drainage of the pathological focus. Dressing No. 1c was established to be promising in cases without inflammatory processes in the extracted tooth socket, where high adhesion to surrounding tissues is initially required for ensuring the tightness and preservation of a blood clot in the wound. 

scholarly journals Extracellular Vesicles in Regeneration and Rehabilitation Recovery after Stroke

Biology ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 843
Author(s):  
Alice Gualerzi ◽  
Silvia Picciolini ◽  
Francesca Rodà ◽  
Marzia Bedoni
Keyword(s):  
Extracellular Vesicles ◽  
Optimal Recovery ◽  
Special Focus ◽  
Stroke Event ◽  
Injured Brain ◽  
Long Time ◽  
Inflammatory Processes ◽  
Complex Events ◽  
The Brain ◽  
Potential Therapeutics

Patients that survive after a stroke event may present disabilities that can persist for a long time or permanently after it. If stroke prevention fails, the prompt and combinatorial intervention with pharmacological and rehabilitation therapy is pivotal for the optimal recovery of patients and the reduction of disabilities. In the present review, we summarize some key features of the complex events that occur in the brain during and after the stroke event, with a special focus on extracellular vesicles (EVs) and their role as both carriers of biomarkers and potential therapeutics. EVs have already demonstrated their ability to be used for diagnostic purposes for multiple brain disorders and could represent valuable tools to track the regenerative and inflammatory processes occurring in the injured brain after stroke. Last, but not least, the use of artificial or stem cell-derived EVs were proved to be effective in stimulating brain remodeling and ameliorating recovery after stroke. Still, effective biomarkers of recovery are needed to design robust trials for the validation of innovative therapeutic strategies, such as regenerative rehabilitation approaches.

scholarly journals PREVENTION OF TOXIC-ALLERGIC REACTIONS WHEN USING DENTURES AND DEVICES

2020 ◽  
Vol 16 (3) ◽  
pp. 139-146
Author(s):  
Aleksey Zotov ◽  
Anna Podoprigora ◽  
Yuliya Komarova ◽  
Edvard Kalivradzhiyan ◽  
Ilya Stepanov ◽  
...  
Keyword(s):  
Mucous Membrane ◽  
Chemical Elements ◽  
The Body ◽  
Allergic Reactions ◽  
State University ◽  
Acrylic Polymer ◽  
Quantitative Distribution ◽  
Removable Plate ◽  
Inflammatory Processes ◽  
Cytological Characteristics

Subject. Today, nanoparticles of chemical elements that make up the body are of particular interest. Such nanomaterials usually do not cause allergic reactions, they can potentially be broken down and removed from it, and, for example, drugs can be placed in the pores of these materials. At the Department of Prosthetic Dentistry of V.G. N.N. Burdenko together with Voronezh State University developed a polymer modified with nanosized silver particles, which was successfully tested on patients in the manufacture of removable plate prostheses. However, there is no data on the effect of this polymer in patients with complex jaw pathology in combination with somatic pathology, in which visible changes occur in the oral cavity. Goal ― to consider the problem of prevention of toxic-allergic reactions when using complex-jaw prostheses and devices. To study the state of the oral microbiocenosis and the cytological characteristics of the mucous membrane in patients with apparatus bases made of a polymer modified with nanoscale silver. Materials and methods. 80 people were examined and 60 patients were treated for complete absence of teeth with various degrees of atrophy according to A.I.Doynikov (1967) I, II, III, IV, V, with a uniform quantitative distribution in groups. Methodology. 80 people were examined and 60 patients were treated for complete absence of teeth with various degrees of atrophy according to A.I.Doynikov (1967) I, II, III, IV, V, with a uniform quantitative distribution in groups. Results. The dynamics of the inflammatory processes of the mucous membrane of the prosthetic bed under the bases of removable jaw devices made by the known method and with bases from modified materials was studied. A complex of personalized prevention of complications associated with the action of basic polymers has been developed. Conclusion. Obtained by analyzing the results of the study, it was possible to create, on the basis of the use of modified acrylic polymer as the material of the bases of removable prostheses and devices, a program for individual prevention of the inflammatory complications induced by them from the mucosa of the prosthetic bed, the efficiency level of which is at least 60 %. This predisposes to recommendations for the further implementation of the modified nanosilver acrylic polymer in practical dentistry.

Macroscopic changes of the cats liver during diseases.

2020 ◽  
Vol 1 ◽  
pp. 105-109
Author(s):  
D.E. Levterov ◽  
Keyword(s):  
Mucous Membrane ◽  
Bone Tumors ◽  
Inflammatory Cells ◽  
Cortical Layer ◽  
High Permeability ◽  
Liver Cysts ◽  
Lower Jaw ◽  
Pass Through ◽  
Mechanisms Of Development ◽  
Diagnosis Of Diseases

The main and most accessible part of pathomorphological research is the macro-scopic method, which makes it possible to effectively diagnose various animal diseas-es. Changes in the liver, as an organ in-volved in the process of digestion and meta-bolic reactions, are important in examining the pathogenesis and diagnosis of diseases. A macroscopic study of the liver of 15 cats with various diseases was performed. Among the animals subjected to a pathoana-tomic autopsy there were 9 cats and 6 cats, from 2.5 months to 18 years old. The most common changes were liver dystrophy: pro-tein, fat, protein-fat, which were registered in many diseases. The main diseases diag-nosed at the autopsy were infectious cat peritonitis, dipylidiosis, liver lipidosis, dis- eases of the digestive canal and kidneys, and bone tumors of the lower jaw. Alterative hepatitis was observed in an animal with infectious cat peritonitis. This disease was also accompanied by fibrinous perihepatitis. Cysts in the liver were observed with a simi-lar lesion of the kidneys. The mechanisms of development of iden-tified dystrophies are infiltration of substanc-es entering the liver with blood, and decom-position – the breakdown of complex chemi-cal compounds. Fibrinous perihepatitis is associated with the activity of macrophages that cause high permeability of the wall of small blood vessels, which makes it possible for large fibrinogen molecules to pass through, followed by the formation and ac-cumulation of fibrin. Alterative hepatitis with numerous small foci of necrosis is obvi-ously also associated with the activity of these inflammatory cells. Liver cysts, com-bined with similar changes in the cortical layer of the kidneys, and in one case, the mucous membrane of the bladder, indicate the innate nature of this pathology

scholarly journals STUDIES ON A-AVITAMINOSIS IN CHICKENS

1930 ◽  
Vol 52 (4) ◽  
pp. 519-532 ◽  
Author(s):  
Oskar Seifried
Keyword(s):  
Respiratory Tract ◽  
Mucous Membrane ◽  
Vitamin A Deficiency ◽  
Surface Epithelium ◽  
Protective Mechanism ◽  
Nasal Discharge ◽  
Upper Respiratory Tract ◽  
Interesting Insight ◽  
Mucous Membranes ◽  
Inflammatory Processes

1. The principal tissue changes in the respiratory tract of chickens caused by a vitamin A deficiency in the food are, first, an atrophy and degeneration of the lining mucous membrane epithelium as well as of the epithelium of the mucous membrane glands. This process is followed or accompanied by a replacement or substitution of the degenerating original epithelium of these parts by a squamous stratified keratinizing epithelium. This newly formed epithelium develops from the primitive columnar epithelium and divides and grows very rapidly. The process appears to be one of substitution rather than a metaplasia, and resembles the normal keratinization of the skin or even more closely the incomplete keratinization of the mucous membranes (e.g., the esophagus or certain parts of the tongue of chickens). In this connection findings have been described which not only afford an interesting insight into the complicated mechanism of keratinization, but also show probable relations between keratinization and the development of Guarnieri's inclusion bodies. Balloon and reticular degeneration of the upper layers of the new stratified epithelium has been frequently observed. All parts of the respiratory tract are about equally involved in the process; and the olfactory region as well, so that the sense of smell may be lost. The lesions, which first take place on the surface epithelium and then in the glands, show only minor differences. 2. The protective mechanism inherent in the mucous membranes of the entire respiratory tract is seriously damaged or even entirely destroyed by the degeneration of the ciliated cells at the surface and the lack of secretion with bactericidal. properties. Secondary infections are frequently found, and nasal discharge and various kinds of inflammatory processes are common, including purulent ones, especially in the upper respiratory tract, communicating sinuses, eyes and trachea. The development of the characteristic histological process is not dependent upon the presence of these infections, since it also takes place in the absence of infection. 3. The specific histological lesions make it possible to differentiate between A-avitaminosis and some infectious diseases of the respiratory tract. These studies we hope will serve as a basis for further investigations on the relationship between A-avitaminosis and infection in general.

scholarly journals Evaluaton of the Use of Bone Implants as a Therapy for Deep Defects in the Parodoncium

2014 ◽  
Vol 15 (2) ◽  
pp. 79-82
Author(s):  
Momir Stevanović ◽  
Dušica Ćirić
Keyword(s):  
Tricalcium Phosphate ◽  
Periodontal Regeneration ◽  
Clinical Problem ◽  
Periodontal Pocket ◽  
Control Group ◽  
Lower Jaw ◽  
Standard Application ◽  
Inflammatory Processes ◽  
Infrabony Defects ◽  
And Control

ABSTRACT Reconstruction of infrabony defects created by the chronic inflammatory processes of parodontopathy represents a major clinical problem in paradontology. The objective of this research was to compare and evaluate the efficiency of two bone substituents at reversing the deep infrabony defects in the paradentium after the application of a new “Biohapel” material consisting of biphasic calcium phosphate/poly DL-lactide-co-glycolide. This study included 12 patients of both genders with an average age of 49.7 years who were suffering from clinically manifested parodontopathy. The main criteria for selecting patients were the presence of six similar infrabony periodontal defects that were at least 4 mm deep and in the lower side of the teeth on both sides of the jaw. After applying a basic causal parodontopathy treatment, defects were divided into two groups, including an experimental group (n=72) in which defects were reconstructed using the “Biohapel” bone substituent (on one side of the lower jaw) and a control group (n=72) in which infrabony defects were reconstructed using β tricalcium phosphate (βTCP) (CerasorbR), a preparation very commonly applied in regenerative parodontopathy treatment (on the other side of the lower jaw). Markers to assess treatment efficacy were determined before surgery and 6 months after surgery by measuring the depth of periodontal pocket and the level of the junctional epithelium. We observed statistically significant differences in the periodontal regeneration markers between the experimental and control groups (p<0.05). Application of “Biohapel” during the surgical treatment of infrabony defects in the paradentium significantly improves the bone regeneration of the paradentium when compared with the standard application of β-tricalcium phosphate .

Sign in / Sign up

Export Citation Format

Share Document