scholarly journals Current state of the art of protein therapy

2021 ◽  
Vol 18 (3) ◽  
pp. 34-49
Author(s):  
B. A. Volter
Keyword(s):  
State Of The Art ◽  
Vaccine Therapy ◽  
Protein Therapy ◽  
Current State ◽  
Protein Nature ◽  
The Subject

The subject of my lecture is the doctrine of the nonspecific treatment of infectious and other diseases, which, under the name Proteinkrpertherapie, currently combines a number of long-known therapeutic methods, such as: vaccine therapy, serotherapy, organotherapy, as well as those departments of pharmacotherapy where the current principles are various substances of a protein nature.

scholarly journals An Overview of Lidar Imaging Systems for Autonomous Vehicles

2019 ◽  
Vol 9 (19) ◽  
pp. 4093 ◽  
Author(s):  
Santiago Royo ◽  
Maria Ballesta-Garcia
Keyword(s):  
Autonomous Vehicles ◽  
State Of The Art ◽  
Autonomous Vehicle ◽  
Single Point ◽  
Imaging Systems ◽  
Light Sources ◽  
Final Solution ◽  
Large Uncertainty ◽  
Current State ◽  
The Subject

Lidar imaging systems are one of the hottest topics in the optronics industry. The need to sense the surroundings of every autonomous vehicle has pushed forward a race dedicated to deciding the final solution to be implemented. However, the diversity of state-of-the-art approaches to the solution brings a large uncertainty on the decision of the dominant final solution. Furthermore, the performance data of each approach often arise from different manufacturers and developers, which usually have some interest in the dispute. Within this paper, we intend to overcome the situation by providing an introductory, neutral overview of the technology linked to lidar imaging systems for autonomous vehicles, and its current state of development. We start with the main single-point measurement principles utilized, which then are combined with different imaging strategies, also described in the paper. An overview of the features of the light sources and photodetectors specific to lidar imaging systems most frequently used in practice is also presented. Finally, a brief section on pending issues for lidar development in autonomous vehicles has been included, in order to present some of the problems which still need to be solved before implementation may be considered as final. The reader is provided with a detailed bibliography containing both relevant books and state-of-the-art papers for further progress in the subject.

Needle Heating during High-Speed Sewing

1969 ◽  
Vol 39 (2) ◽  
pp. 101-120 ◽  
Author(s):  
S. P. Hersh ◽  
P. L. Grady
Keyword(s):  
High Speed ◽  
Quantitative Methods ◽  
State Of The Art ◽  
Review Of The Literature ◽  
Sewing Thread ◽  
Current State ◽  
Fabric Structure ◽  
Extensive Field ◽  
The Subject

A review of the literature and extensive field interviews have been conducted on the subject of needle heating in high-speed sewing. As a result of this investigation, a survey of the current state of the art and knowledge available in the field has been completed and is presented in the following categories: (1) the nature of the problem and the difficulties which arise in commercial operations; (2) quantitative methods of measuring needle temperatures; (3) the influence of machine factors such as sewing speed, length of sewing time, and needle design on the heat generated during sewing; (4) the influence of material factors such as fabric structure and finish, layers of fabric, and sewing thread on needle heating; (5) techniques for alleviating needle heating problems; and (6) the mechanism of generation and dissipation of heat in the sewing process. Some heretofore unpublished data are presented.

scholarly journals Assessing Sustainability in the Shipbuilding Supply Chain 4.0: A Systematic Review

2020 ◽  
Vol 12 (16) ◽  
pp. 6373 ◽  
Author(s):  
Magdalena Ramirez-Peña ◽  
Francisco J. Abad Fraga ◽  
Jorge Salguero ◽  
Moises Batista
Keyword(s):  
Systematic Review ◽  
Supply Chain ◽  
Scientific Community ◽  
State Of The Art ◽  
Current State ◽  
Enabling Technologies ◽  
Global Vision ◽  
The Subject ◽  
Key Enabling Technologies ◽  
Do So

The supply chain is currently taking on a very important role in organizations seeking to improve the competitiveness and profitability of the company. Its transversal character mainly places it in an unbeatable position to achieve this role. This article, through a study of each of the key enabling technologies of Industry 4.0, aims to obtain a general overview of the current state of the art in shipbuilding adapted to these technologies. To do so, a systematic review of what the scientific community says is carried out, dividing each of the technologies into different categories. In addition, the global vision of countries interested in each of the enabling technologies is also studied. Both studies present a general vision to the companies of the concerns of the scientific community, thus encouraging research on the subject that is focused on the sustainability of the shipbuilding supply chain.

Slipping on Concrete: A Case Study

2009 ◽  
Author(s):  
Ralph L. Barnett ◽  
Adam A. E. Ziemba ◽  
Theodore Liber
Keyword(s):  
State Of The Art ◽  
Classical System ◽  
Modern Theory ◽  
Safety Study ◽  
Current State ◽  
Classical Criterion ◽  
Average Coefficient ◽  
Parking Lot ◽  
The Subject

The notion of slipperiness is rarely associated with a concrete walkway. The aggressive nature of this surface invariably satisfies the classical criterion of a safe floor. The case study described in this paper challenges this preconception. It involves a woman who enters an indoor stairwell of a parking lot and slips on the dry concrete landing while approaching the stairs with her arm outstretched to grasp the railing. The current state-of-the-art of human slipping provides this victim with no remedy at law. This paper presents a forensic and safety study that focuses on slip and fall. Slip is usually analyzed by a classical system that has no redeeming features. This protocol provides a go/no-go criterion that proclaims a walking surface safe if its interaction with a surrogate material (e.g. leather) produces an average coefficient of friction greater than 0.5. It turns out that many walkers slip on such mythical “safe” floors. The subject case adopts a modern theory of human slipping that quantitatively predicts the number of walkers who will slip on a given surface including concrete landings.

scholarly journals Electrocardiogram in Haïssaguerre Syndrome (Early Repolarization)

2020 ◽  
Vol 32 (3) ◽  
pp. 155-162
Author(s):  
Raphael Chiarini ◽  
Carlos Eduardo Duarte ◽  
João Durval Ramalho Trigueiro Mendes Junior ◽  
José Tarcísio Medeiros de Vasconcelos ◽  
Silas dos Santos Galvão Filho
Keyword(s):  
Risk Stratification ◽  
State Of The Art ◽  
High Impact ◽  
Early Repolarization ◽  
Idiopathic Ventricular Fibrillation ◽  
Future Studies ◽  
Current State ◽  
Real Value ◽  
The Subject

Introduction: Early repolarization pattern (ERP) has traditionally been related as a benign variant of electrocardiography (ECG). However, since 2008, when two studies were published for Haïssaguerre et al. and Rosso et al., with evidence of a higher prevalence of ERP in people with primary or idiopathic ventricular fibrillation (VF), this paradigm has been challenged. Objective: To conduct a thorough review of early repolarization and current state of the art regarding risk stratification in these patients. Methods: Literature review on the subject evaluating the works published in high impact journals. Conclusion: The correlation of risk factors and the real value of the various methods currently available as possible risk stratifiers is still controversial. Advances in genetics and molecular biology may in the future help in understanding the pathophysiology and better risk stratification in this population. In this context, the standardization of the definition and classification of early repolarization is imperative, as it will serve as a substrate for future studies and researches in the area.

State-of-the-Art of Seismic Response of Utility Tunnel

2013 ◽  
Vol 353-356 ◽  
pp. 2202-2205
Author(s):  
Lu Zhen Jiang
Keyword(s):  
Numerical Simulation ◽  
Theoretical Analysis ◽  
Seismic Response ◽  
Experimental Research ◽  
State Of The Art ◽  
Wave Excitation ◽  
Current State ◽  
The Future ◽  
The Subject ◽  
Utility Tunnel

A state-of-the-art review of the seismic response of utility tunnels is presented. The objectives of the review are to present a view of current state of utility tunnel and to examine trends in the future. The review includes: the theoretical analysis, numerical simulation and experimental research on the utility tunnel under earthquake wave excitation. Based on the review, the future scope of work on the subject is outlined.

scholarly journals Social Science and Latin America: Promises to Keep

2000 ◽  
pp. 798-810 ◽  
Author(s):  
Roberto Briceño-León ◽  
Heinz R. Sonntag
Keyword(s):  
Latin America ◽  
Social Science ◽  
State Of The Art ◽  
Academic Life ◽  
World Congress ◽  
Current State ◽  
International Sociological Association ◽  
The Subject ◽  
Immanuel Wallerstein ◽  
Intense Debate

During his intellectual and academic life, Immanuel Wallerstein always makes contributions that are the subject of intense debate and controversy. Now he has given us, as an additional legacy to complete his four years of brilliant, hard, and—why not?—controversial work on behalf of our science as the President of the International Sociological Association (ISA), and as a contribution to commencing the 14th World Congress, another powerful provocation regarding the current state of the art of sociology, or better put, social science. He has done this with reference to the contributions sociological thinking has made, the challenges that social science has encountered, and the promises that social science should ful?ll. The provocation is broad and taken to its extreme.

Behavioral Genetics: Concepts for Research and Practice in Language Development and Disorders

1995 ◽  
Vol 38 (5) ◽  
pp. 1126-1142 ◽  
Author(s):  
Jeffrey W. Gilger
Keyword(s):  
Language Development ◽  
Behavioral Genetics ◽  
State Of The Art ◽  
Genetic Research ◽  
Great Promise ◽  
Behavioral Genetic ◽  
Fine Grained ◽  
Future Goals ◽  
Current State ◽  
Research Designs

This paper is an introduction to behavioral genetics for researchers and practioners in language development and disorders. The specific aims are to illustrate some essential concepts and to show how behavioral genetic research can be applied to the language sciences. Past genetic research on language-related traits has tended to focus on simple etiology (i.e., the heritability or familiality of language skills). The current state of the art, however, suggests that great promise lies in addressing more complex questions through behavioral genetic paradigms. In terms of future goals it is suggested that: (a) more behavioral genetic work of all types should be done—including replications and expansions of preliminary studies already in print; (b) work should focus on fine-grained, theory-based phenotypes with research designs that can address complex questions in language development; and (c) work in this area should utilize a variety of samples and methods (e.g., twin and family samples, heritability and segregation analyses, linkage and association tests, etc.).

Schizophrenia Research: Current State of the Art

1976 ◽  
Vol 21 (7) ◽  
pp. 497-498
Author(s):  
STANLEY GRAND
Keyword(s):  
State Of The Art ◽  
Current State

PLANEJAMENTO FAMILIAR COMO ASSUNTO DE MULHER!? PERFIL DE GÊNERO NA PRODUÇÃO CIENTÍFICA NO BRASIL

2019 ◽  
Vol 8 (1) ◽  
pp. 221-235 ◽  
Author(s):  
Daniella De Paula Chiesa ◽  
Mário Antônio Sanches ◽  
Daiane Priscila Simão-Silva
Keyword(s):  
Family Planning ◽  
Scientific Literature ◽  
State Of The Art ◽  
Health Sciences ◽  
Scientific Production ◽  
The State ◽  
Review Of The Literature ◽  
The Subject

O estudo do Planejamento familiar, no contexto da bioética, abre-se para diversas perspectivas, entre elas a valorização dos seus diferentes atores. Situado neste contexto o artigo tem como objetivo identificar o perfil de gênero na produção científica sobre Planejamento Familiar no Brasil, entre 2000 e 2014, assim como a área de formação e especialização dos autores. Foram utilizadas metodologias que permitiram mapear o estado da arte do tema estudado, a partir de uma revisão da literatura. O resultado da pesquisa identifica que a produção científica sobre Planejamento Familiar no Brasil se compõe de perfil destacadamente feminino (71,76%). Dos 73 artigos analisados, 42 (57,53%) o foco do tema está direcionado à mulher assim como evidencia-se a área de ciências da saúde com maior concentração das publicações do tema.  Este aspecto da pesquisa abre para uma realidade complexa onde se buscam criticamente as razões para a pesquisa em Planejamento Familiar ter ênfase na mulher e ser um tema de relevância nas ciências da saúde.Palavras-chave: Produção científica, Planejamento Familiar, Gênero.  ABSTRACT: The study of Family Planning, in the context of bioethics, opens to diverse perspectives, among them the appreciation of their different agents. Situated in this context the article aims to identify the profile of gender in scientific literature on Family Planning in Brazil, between 2000 and 2014, as well as the area of training and specialization of the authors. Methodologies were used which allowed to map the State of the art of the subject studied, from a review of the literature. The results found identify that the scientific production on Family Planning in Brazil is formed with a outstandingly female profile (71,76%). Of the 73 articles examined, 42 (57.53%) the focus of the topic is directed to women as well as showing the health sciences area with highest concentration of publications. This aspect of the research opens to a complex reality where we seek critically the reasons for Research in Family Planning have emphasis on woman and be a topic of relevance in health sciences.Keywords: Scientific Production, Family Planning, Gender.

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