scholarly journals Dynamics of the formation of protection for circulatory bed in bone regenerate

2017 ◽  
Vol 24 (4) ◽  
pp. 43-45
Author(s):  
Vladimir A. Shchyurov ◽  
S. P Boichuk ◽  
V. T Tarchokov ◽  
L. V Mel’nikova

Evaluation of the bone regenerate maturation in 21 patients, aged 27 - 66 years, with closed shoulder fractures was performed in the course of treatment by Ilizarov technique according to the rate of blood supply velocity at functional load and by the value of that load. Examination was performed in 1 and 2 weeks as well as in 1 and 2 months after fixation. Within the first 2 weeks the bone fragments micro mobility at 10 kgF axial load on the extremity made up 194±42 µm. Subsequently as the regenerate became compact the bone fragments micro mobility decreased up to 53±13 µm (p≤0.02). During the fixation period the load tolerance increased from 5 to 15 kgF. The threshold of load tolerance was detected by the occurrence of unpleasant feel- ings the regenerate zone and increased rate of blood circulation in the vessels. At the end of fixation period the rate of blood circulation was decreased by 2 times and practically did not change at increasing loads confirming the formation of the protection system for circulatory bed in the bone regenerate.

Author(s):  
V. A. Shchyurov ◽  
S. P. Boichuk ◽  
V. T. Tarchokov ◽  
L. V. Mel’nikova

Evaluation of the bone regenerate maturation in 21 patients, aged 27 – 66 years, with closed shoulder fractures was performed in the course of treatment by Ilizarov technique according to the rate of blood supply velocity at functional load and by the value of that load. Examination was performed in 1 and 2 weeks as well as in 1 and 2 months after fixation. Within the first 2 weeks the bone fragments micro mobility at 10 kgF axial load on the extremity made up 194±42 µm. Subsequently as the regenerate became compact the bone fragments micro mobility decreased up to 53±13 µm (p≤0.02). During the fixation period the load tolerance increased from 5 to 15 kgF. The threshold of load tolerance was detected by the occurrence of unpleasant feelings the regenerate zone and increased rate of blood circulation in the vessels. At the end of fixation period the rate of blood circulation was decreased by 2 times and practically did not change at increasing loads confirming the formation of the protection system for circulatory bed in the bone regenerate. 


2005 ◽  
Vol 12 (1) ◽  
pp. 11
Author(s):  
A. G Guseinov

In treatment of 87 patients (main group) with diaphysial shin fractures new techniques and devices for optimization of transosseous extrafocal osteosynthesis by Ilizarov were applied. All techniques and devices, i.e. devices for the perfection of Ilizarov apparatus stability, for bone fragment reposition, console compression arrangement for extrafocal osteosynthesis in commi­nuted fractures, devices for damper compression of bone fragments, for prevention of lower extremity edema at extrafocal osteosynthesis, for provision of early axial loading in Ilizarov apparatus, for activization of osteogenesis using asymmetrical dynamic compression were elabo­rated by the author. Control group (108 patients) was treated by traditional Ilizarov technique. Treatment results were assessed at terms from 4 months to 2 years. Data of clinical, X-ray and functional examinations as well as terms of fracture healing, duration of hospitalization and terms of working ability restoration were better in the main group as compared to the control one. In the main group good results were achieved in 47.1%c, satisfactory — in 49.4%, poor — in 3.5% of cases, in control group — 30.6%, 63.0%, 6.4%, respectively. Author believes that further perfection of Ilizarov technique is reasonable.


1956 ◽  
Vol 185 (1) ◽  
pp. 125-126
Author(s):  
H. L. Popper ◽  
N. C. Jefferson ◽  
H. Necheles

In previous work it was found that a relatively small collateral blood supply by the phrenic arteries mainly was adequate to maintain the liver following ligation of the hepatic artery and the portal vein. In order to demonstrate the pathways of the collaterals, normal dogs and dogs that had survived ligation of either the hepatic artery or the portal vein for some time were used. A plastic dissolved in acetone that gelled with water, or mineral oil, or red lead dye suspension, was used for injection. The acetone content of the plastic medium produced toxic reactions. The media were injected into branches of the intact portal vein or into the intact hepatic artery, or into the hepatic artery or the portal vein above the ligature. Blocking of the intrahepatic branches of the hepatic artery caused liver necrosis in every instance, while blocking of the intrahepatic branches of the portal vein was tolerated. Thus, blocking of branches of the hepatic artery demonstrates that the essential collateral arterial blood supply had been interrupted.


2014 ◽  
Vol 95 (3) ◽  
pp. 392-394
Author(s):  
O N Yamshchikov ◽  
D A Markov ◽  
S A Emelyanov ◽  
K P Zvereva ◽  
A E Bychkov

Aim. To perform the comparative analysis of osteosynthesis stability in splintered fractures on the example of modeled fractures of femur with metalwork. Methods. Bone fragments fixation methods using internal fixators, blocking intramedullary nails, external fixation devices. Round wooden rod with external diameter of 35 mm, internal diameter of 25 mm, which was saw in the middle with two cuts directed at an angle of 45° to the rod axis to form the triangle fragment, was picked for femur model for the purpose of experiment. The stability of bone fragments fixation using plates with angle stability, pin- and nail-type external fixation devices and blocking intramedullary nails was assessed. To test the stability of the «bone-fixing device» complex, torsional test machine КМ-50-1 №66, power press П-10 №92, pull test machine Р-10 №1677 were used. Results. Compared to external fixation device, fixation using plates with angle stability was 6 times more stable at axial load and by 43.5% at lateral load. The stability of blocking intramedullary nail at axial load was higher compared to external fixation device. At rotary load, the stability of blocking intramedullary nail was 2 times lower compared to external fixation device. Conclusion. On a model of splintered double-lever femur fractures, fixation using plates with angle stability was the most stable fixation mode.


2004 ◽  
Vol 11 (1) ◽  
pp. 9-13
Author(s):  
Z G Natsvlishvili ◽  
E V Ogarev ◽  
A K Morozov ◽  
G I Khokhrikov ◽  
Z G Natsvlishvili ◽  
...  

The peculiarities of cervical spinal cord blood supply were studied on 34 autopsied specimens. It was detected that both a. anterior spinalis, gone away from intracerebral zone of a. vertebralis and a. anterior radiculo-medullaris approaching the a. anterior spinalis system with C2-8 radicis played an equally important role in blood supply of the cervical spinal cord. The most significant importance had C5 left and C7 right a. radiculo-medullaris, that were noted in 65% of specimens. For cervical spinal cord the branching type of blood supply was more characteristic (67,7% of cases). In that type the number of a. radiculo-medullaris ranged from 2 to 8 (mean 4,4). That peculiarity significantly increases the probability of restoration of blood circulation in injury or other pathology of a. anterior spinalis.


1937 ◽  
Vol 33 (3) ◽  
pp. 255-258
Author(s):  
A. G. Pershin ◽  
N. E. Filinov

The intensity of metabolism in the tissues of the body largely depends on the rate and amount of circulating blood. With an increase in the work of organs, the need for their blood supply also increases. The blood circulation rate depends on many factors, of which the main ones are: 1) the functional state of the myocardium, 2) the state of vascular tone, 3) the amount of circulating blood, 4) blood viscosity, 5) basal metabolism, etc.


Morphologia ◽  
2021 ◽  
Vol 15 (3) ◽  
pp. 84-88
Author(s):  
V.V. Zherebkin ◽  
D.N. Shiyan ◽  
I.V. Borzenkova ◽  
P.V. Tkachenko

Background. Big epidemiological studies have revealed a link between osteoarthritis and some cardiovascular diseases such as coronary heart disease, heart failure, cerebral circulation disorders, vascular diseases and diabetes mellitus. Objective. Determination of the features of morphological changes in the synovial membrane of the joint, articular cartilage and subchondral bone in patients with cardiovascular diseases. Methods. Histological studies of articular tissues of 30 amputated lower extremities in persons with vascular diseases of the lower extremities were performed. Results. In all samples of the capsule of the knee joint, gross violations of the microcirculatory canal and histological changes of osteoarthritis and subchondral osteoporosis were revealed. At the same time, the revealed changes in the articular cartilage and subchondral bone were more pronounced in the patellar, which in the knee joint carries a negligible functional load, but receives blood supply only from the vessels of the articular capsule than in the joint surface of tibia, carrying the lion's share of the functional load on the knee joint, but receiving blood supply from the posterior tibial artery. Conclusion. The revealed features of morphological changes in articular tissues in vascular diseases of the lower extremities indicate that these diseases play an important role in the development of osteoarthritis and are more significant than the functional load on the joint. Further studies of the features of morphological changes in articular tissues in the samples of various contingents of persons are needed.


2021 ◽  
Vol 14 (1) ◽  
pp. 114-122
Author(s):  
I.S. Shormanov ◽  
◽  
S.V. Kulikov ◽  
A.S. Solovyov ◽  
◽  
...  

Introduction. It is known that prolonged bladder obstruction caused by prostatic hypertrophy leads to serious structural changes in the bladder wall. However the detailed morphogenesis of this process, the features of the compensatory-adaptive reactions of the its vascular bed and the role of existing background diseases in this process, as well as age-related changes are still unclear. Aim of our study was to discover the features of the structural rearrangement of the bladder and its vasculature in elderly and senile people with BPH. Materials and methods. Autopsy material from 25 men 60-80 years old who had no urological pathology and from 25 men of the same age who had BPH without signs of urinary bladder decompensation was studied. There were 10 men aged 20-30 who died as a result of injuries in control group. Results. Histological and immunohistochemical studies revealed a pronounced structural reorganization of the bladder wall and its vasculature in patients with BPH. This process is superimposed on the already existing involutive changes in the detrusor such as its atrophy, sclerosis of the intermuscular stroma and neurodegenerative changes. The compensatory hypertrophy of detrusor and changes in its vasculature to regulate the local hemodynamics develop in men with ifravesical obstruction. Such changes in the arterial bed include bundles of intimate muscles, muscular-elastic sphincters and polypoid pillows formations. They provide a normal blood supply of the intact parts of the detrusor at the cost of deterioration the blood supply of its areas with atrophic and sclerotic changes. Regulatory changes such as muscle "couplings", muscle rollers and valves were also revealed in the veins. The contraction of this musculature imparts an impulse to the movement of venous blood to the heart and relaxation promotes its deposition. The valves are able to prevent the development of blood regurgitation. Conclusions. Рrostatic hyperplasia and infravesical obstruction cause the functional load on the detrusor increases, which leads to its local hypertrophy. This process occurs against the background of age-related changes. There is also a structural reorganization of the vascular bed of the bladder, the role of which is to redistribute blood flow in favor of detrusor sites that are subjected to greater functional load.


2020 ◽  
Vol 87 (11-12) ◽  
pp. 71-75
Author(s):  
A. O. Zhernov ◽  
O. M. Kovalenko ◽  
O. A. Zhernov

Objective. To improve the results of surgical treatment in patients with deep electric burns of the hand, using local vascularized flaps, based on perforant vessels. Materials and methods. Analysis of the treatment results in 17 patients, suffering electric trauma of the hand was conducted, the defects plasty was performed, using local vascularized flaps, based on perforant vessels of the hand. Results. In 17 patients 20 flaps were formed. Application of revascularization procedures have permitted to obtain good results in immediate period in 76.5% patients, and satisfactory - in 13.5% patients, in late follow-up period good results - in 88.2% patients, and satisfactory - in 11.8% patients. Conclusion. The transplant, owing own blood circulation and locally vascularized flaps, based on perforant vessels, which are formed on non-injured parts of the hand, guarantee the blood supply restoration in the zone of electric thermic affection as well as the wound defect closing.


Author(s):  
John L. Beggs ◽  
Peter C. Johnson ◽  
Astrid G. Olafsen ◽  
C. Jane Watkins

The blood supply (vasa nervorum) to peripheral nerves is composed of an interconnected dual circulation. The endoneurium of nerve fascicles is maintained by the intrinsic circulation which is composed of microvessels primarily of capillary caliber. Transperineurial arterioles link the intrinsic circulation with the extrinsic arterial supply located in the epineurium. Blood flow in the vasa nervorum is neurogenically influenced (1,2). Although a recent hypothesis proposes that endoneurial blood flow is controlled by the action of autonomic nerve fibers associated with epineurial arterioles (2), our recent studies (3) show that in addition to epineurial arterioles other segments of the vasa nervorum are also innervated. In this study, we examine blood vessels of the endoneurium for possible innervation.


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