scholarly journals Efficacy of the Cognitive and Exposure Therapy in the Treatment of Obsessive-Compulsive Disorder

2013 ◽  
Vol 11 ◽  
pp. 1-9
Author(s):  
Hiva Mahmoodi ◽  
Hasan Gharibi ◽  
Mohamad Khaledian
Keyword(s):  
Cognitive Therapy ◽  
Obsessive Compulsive Disorder ◽  
Exposure Therapy ◽  
Analysis Of Covariance ◽  
Control Group ◽  
Obsessive Compulsive ◽  
Statistical Population ◽  
Compulsive Disorder ◽  
Significant Difference ◽  
Experimental Group

The aim of this study was the investigation of the efficacy of the Cognitive and Exposure therapy on the treatment of obsessive- compulsive disorder. This study is experimental expanded with multiple group pre-test, post-test. The statistical population of this study are included all patients with OCD, referred to clinical centers, hospitals and private clinics and counseling centers in Saghez and Boukan citiesat the age of 40-20 years. The statistical sample of this study is included 45 patientswith Obsessive Compulsive Disorder, Who were selected randomly. Cognitive therapy was administered for the first experimental group and the second experimental group receives exposure therapy while the control group received no treatment. Subscales Madsly questionnaire was usedfor data gathering for OCD. For data analysis, multivariate analysis of covariance (MANCOVA) and least significant difference test to compare scores differences between pretest - posttest variables in the experimental and control groups was used. Findings showed that Cognitive and Aversion Therapy on the control group has a significant impact on the improvement of obsession, check out, washing, slowness and obsessive doubts. The results showed that Whittal Cognitive Therapy more impact on the reduction of obsessions in comparsion with Exposure therapy.

Reducing the Social Stigma Associated with Obsessive Compulsive Disorder: A Controlled Trial of an Intervention Program in a Turkish Community Sample

2020 ◽  
Vol 20 (2) ◽  
pp. 101-120
Author(s):  
Ayça Aktaç Gürbüz ◽  
Orçun YORULMAZ ◽  
Gülşah DURNA
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Intervention Program ◽  
Controlled Trial ◽  
Community Sample ◽  
Case Vignette ◽  
Control Group ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Significant Difference ◽  
The Impact

Scientific research into the reduction of stigmatization, particularly related to specific problems such as Obsessive-Compulsive Disorder (OCD), is scarce. In the present study, we examine the impact of a video-based antistigma intervention program for OCD in a pretest-posttest control group research. After being randomly assigned to either an intervention (n= 101) or control group (n= 96), the participants reported their attitudes on a hypothetical case vignette before and after OCD vs. Multiple Sclerosis (MS) videos, and again six months later as a follow up assessment. The mixed design analyses for the group comparisons indicated that although there was no significant difference in the measures of the control group, the participants watching the anti-stigma OCD video, in which the focus was psychoeducation and interaction strategies, reported significantly lower scores on social distances and negative beliefs for the case vignettes they read, and this difference was maintained six months later. Then, the present results indicate the effectiveness of our anti-stigma intervention program for OCD. Interventions to reduce stigmatization can also be viewed as effective tools for changing the attitudes of people toward OCD, although further research and applications are needed related to specific disorders if a longlasting impact is to be achieved.

scholarly journals Assessment of in Obsessive Compulsive Disorder

2021 ◽  
pp. 105-114
Author(s):  
Sarah Alaa Mohsen ◽  
Fatma Ahmed El Deeb ◽  
Ehab Sayed Ramadan ◽  
Mai Abd El-Raouf Eissa
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Test Performance ◽  
Age Of Onset ◽  
Neuropsychological Test ◽  
Control Group ◽  
Obsessive Compulsive ◽  
Cross Sectional ◽  
Compulsive Disorder ◽  
Group I ◽  
Significant Difference

Background: Obsessive compulsive disorder (OCD) is a common and potentially debilitating disorder. Neuropsychological assessment provides unique complementary information that is critical for evaluating higher cortical abilities. This study aimed to assess the neuropsychological functions in OCD patients which can then point to the brain structures or pathways and to study the correlation between these assessments and different clinical variables. Methods: This cross-sectional case control study had included sixty patients who were divided into two groups, Group I: thirty OCD patients diagnosed by DSM-IV and Group II: thirty healthy controls who were recruited from the community, matched with patients’ age, gender, and education. Results: The age of onset in our study was 19.13 ± 0.35 years, the mean duration was 7.44 ± 3.88 years, 40% of the studied cases had severe OCD symptoms and 33.3% of them were compulsive cleaners. There was a high significant difference between the two groups regarding WCST in favor of the control group. There was a high significant difference between the two groups regarding ROCF where the control group showed better results than the OCD patients. Conclusions: Neuropsychological test performance remains an informative and objective means of investigation, especially when applied to psychiatric disorders. The executive functions in OCD patients were impaired in comparison to the normal study subjects.

MINDFULNESS BASED COGNITIVE THERAPY AND SYMPTOMS SEVERITY IN PATIENTS WITH OBSESSIVE COMPULSIVE DISORDER

2021 ◽  
pp. 33-34
Author(s):  
Neha Farheen Mushtaq ◽  
G Venkatesh Kumar
Keyword(s):  
Cognitive Therapy ◽  
Obsessive Compulsive Disorder ◽  
Behavioral Therapy ◽  
Work Relationships ◽  
Control Group ◽  
Obsessive Compulsive ◽  
Post Intervention ◽  
Control Group Design ◽  
Compulsive Disorder

BACKGROUND: Obsessive Compulsive Disorder (OCD) is a mental disorder characterized by the presence of obsessions and compulsions with lifetime prevalence of around 2%-3%. Increase in symptoms severity often signicantly seen impairment with work, relationships and other responsibilities. Therefore, timely and effective intervention is required. Literature favors cognitive Behavioral therapy (CBT) as intervention in the management of symptoms severity. AIM: The present study attempts to see the role of mindfulness based cognitive therapy in reducing symptoms severity in OCD. METHODS AND MATERIALS: Pre- and post- MBCT intervention with a control group design were used to conduct this study involving 34 patients with OCD. Patients were equally distributed in two groups where one group was given intervention Mindfulness based cognitive therapy (MBCT) sessions for 8 weeks. Pre- and post- intervention assessment was done using Yale-Brown Obsessive Compulsive Scale (YBOCS) symptoms severity. And the results were compared. RESULTS: Obtained research data indicates that there is a signicant declined in the composite score on YBOCS symptoms severity at post intervention assessment in the group which had been undergone MBCTas compare to the other group. CONCLUSION: Findings revealed that MBCThas a signicant effect on reducing symptoms severity in patients with OCD.

IMPACT OF MINDFULNESS BASED COGNITIVE THERAPY ON RESPONSE INHIBITION IN ADULTS WITH OBSESSIVE COMPULSIVE DISORDER

2021 ◽  
pp. 44-45
Author(s):  
Neha Farheen Mushtaq ◽  
G Venkatesh Kumar
Keyword(s):  
Cognitive Therapy ◽  
Obsessive Compulsive Disorder ◽  
Response Inhibition ◽  
Stroop Effect ◽  
Control Group ◽  
Obsessive Compulsive ◽  
Post Intervention ◽  
Control Group Design ◽  
Compulsive Disorder ◽  
The Impact

Background: 1. Aim: The present study attempts to see the impact of Mindfulness Based Cognitive Therapy on response inhibition ability in adults with Obsessive Compulsive Disorder (OCD) Methods and Materials: MBCT was applied on Pre- and post-assessments as intervention with a control group design were used to conduct this study including 34 patients with OCD. Clients were equally distributed in two groups where one group was given intervention Mindfulness based cognitive therapy (MBCT) sessions for 8 weeks. Pre- and post- intervention assessment was done using The Stroop Color and Word Test (SCWT) and the results were compared. Results: Obtained research data indicates that there was no signicant in the stroop effect between the group which had been undergone MBCT as compared to the other group. Conclusion: Findings revealed that MBCT did not had signicant effect on overall enhancement of stroop effect in adults with OCD

scholarly journals Relationship between Obsessive-compulsive Disorder and Overactive Bladder Syndrome

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Farzad Allameh ◽  
Mahtab Motamed ◽  
Morteza Fallah-Karkan ◽  
Mohammad Poury ◽  
Saba Faraji ◽  
...  
Keyword(s):  
Overactive Bladder ◽  
Obsessive Compulsive Disorder ◽  
Depressive Disorders ◽  
Age Of Onset ◽  
Screen Test ◽  
Control Group ◽  
Case Group ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Significant Difference

Background: Overactive bladder (OAB) syndrome correlates with mental disorders, especially depressive disorders and anxiety disorders, and less frequently obsessive-compulsive symptoms, and occurs mostly in older people. Obsessive-compulsive disorder (OCD) is more frequent in OAB patients. Most OCD people are diagnosed at the age of about 19, typically with an earlier age of onset in boys than in girls, but the onset after age 35 does occur less frequently. Objectives: This study aimed to evaluate the relationship between OCD and OAB. Methods: In this case-control study, 1,160 cases who were over 18 years old who were referred to the urodynamic clinic of Shohada-e-Tajrish center from June 2013 to February 2018 in Tehran, Iran, enrolled of whom 580 were considered the control group who were non-OAB patients, and 580 subjects were considered the case group who were OAB patients. The diagnosis of OAB was confirmed by a single urologist. All cases had detrusor overactivity (DO) in urodynamic study (UDS). The OAB-validated 8-questionnaire screen test (OAB-V8) was conducted, and the diagnosis of OCD was confirmed by a single psychiatrist according to DSM-5 criteria. Moreover, the Yale-Brown questionnaire was completed for each patient to rate the severity of OCD symptoms. Results: About the Yale-Brown Obsessive-compulsive Scale (Y-BOCS) total score, there is a significant difference between patients with obsessive traits and the control group (P < 0.001). OCD scores were significantly higher in the OAB group compared to the control group (P < 0.001). Logistic regression analysis showed that the population of the studied patients with OAB was more probable to have OCD than non-OAB control subjects in aged classified groups (OR: 6.23; P < 0.001). Conclusions: The findings of this study showed that OAB patients reported higher obsessive-compulsive scores (Y-BOCS) compared to the controls. There is an independent correlation between OCD and OAB. However, the linkage between OCD and OAB justifies the need for more research.

scholarly journals THE RATIO OF SECOND FINGER TO FOURTH FINGER IN CHILDREN AND ADOLESCENTS WITH OBSESSIVE COMPULSIVE DISORDER. La proporción entre los dedos índice y anular en los niños y adolescentes que tienen trastorno obsesivo-compulsivo

2016 ◽  
Vol 8 (3) ◽  
pp. 135-141 ◽  
Author(s):  
Hande Ayraler Taner ◽  
Rabet Gozil ◽  
Elvan Iseri ◽  
Ece Buru ◽  
Meltem Bahcelioglu
Keyword(s):  
Children And Adolescents ◽  
Obsessive Compulsive Disorder ◽  
Ring Finger ◽  
Control Group ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Significant Difference ◽  
Healthy Control ◽  
Las Mujeres ◽  
The Right

Objectives: The ratio of the index finger (2D) to the ring finger (4D) is different in males and females. This ratio (2D:4D) has been investigated in a variety of diseases, including autism, schizophrenia, attention deficit hyperactivity disorder, and anxiety disorders. The aim of this study was to investigate the 2D:4D ratio in children and adolescents with obsessive compulsive disorder and to detect any differences in that ratio between participants with obsessive compulsive disorder and a healthy control Material-Methods: The study included 30 children and adolescents diagnosed with obsessive compulsive disorder between ages 7-17 and 90 age-sex matched controls. After the psychiatric evaluations;  finger lenghts were measured with a digital compass. Main results: Girls with obsessive compulsive disorder had greater 2D:4D ratios in their right and left hands than the control group. Although there was no statistically significant difference, the 2D:4D ratio in the right hand was greater in the obsessive compulsive disorder group than in the control group. Conclusion: With relation to obsessive compulsive disorder, some differences were detected in 2D:4D ratios of patients  with obsessive compulsive disorder and control groups but there were no statistically significant results except for that of girls with obsessive compulsive disorder. Further studies are needed to fully understand the relationship between obsessive compulsive disorder and the 2D:4D ratio. Objetivos: La proporción entre los dedos índice y anular es diferente en las mujeres y en los hombres. Esta proporción ha sido estudiada en varias enfermedades como el trastorno de ansiedad, el trastorno de la concentración y la hiperactividad. El objetivo de este estudio era investigar la proporción entre los dedos de índice y anular en los niños y adolescentes que tienen trastorno obsesivo-compulsivo y determinar si existía alguna diferencia entre los participantes con trastorno obsesivo-compulsivo y los del grupo sano. Material y métodos: En el estudio fueron incluidos 30 niños y adolescentes que tenían entre 7 y 17 años de edad con trastorno obsesivo-compulsivo y 90 individuos sanos de igual edad y sexo como el grupo control. Después de las evaluaciones psiquiátricas, la longitud de los dedos fue medida con calibre digital. Resultados: Las niñas y adolescentes con trastorno obsesivo-compulsivo tenían una proporción mayor entre los dedos índice y anular en las manos derechas e izquierdas que el grupo control. Aunque no había una diferencia estadísticamente significativa, la proporción entre los dedos índice y anular en la mano derecha era más grande en el grupo de trastorno obsesivo-compulsivo que el grupo control. Conclusiones: Algunas diferencias fueron detectadas en la proporción entre los dedos índice y anular en los pacientes con trastorno obsesivo-compulsivo y los del grupo control, pero no había resultados estadísticamente significativos excepto las niñas y adolescentes con trastorno obsesivo-compulsivo. Se requieren más estudios para entender completamente la relación entre el trastorno obsesivo-compulsivo y la proporción entre los dedos índice y anular. 

scholarly journals Effectiveness of Cognitive Behavioral Therapy based on Exposure and Response Prevention on Patients with Contamination Obsessive-Compulsive disorder and Scrupulosity

2020 ◽  
Author(s):  
Farzad Farhoodi ◽  
Javad Salehi Fadardi ◽  
Ali Ghanaie Chamanabad ◽  
Seyed Hamid Mirhoseini
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Obsessive Compulsive Disorder ◽  
Behavioral Therapy ◽  
Response Prevention ◽  
Cognitive Behavioral ◽  
Control Group ◽  
Exposure And Response Prevention ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Significant Difference

Introduction: The aim of the present study was to compare the effectiveness of cognitive behavior therapy based on exposure and response prevention on the patients with contamination obsessive-compulsive disorder (OCD) and scrupulosity. Methods: The method was semi-experimental pretest-posttest design by control group. Sixty OCD participants who were suffering from scrupulosity and contamination OCD were diagnosed by means of diagnostic interviewing, Yale-Brown Obsessive-Compulsive Scale and Penn inventory of scrupulosity. They were selected through convenience sampling method and were assigned in two experimental groups and one control group (each group 20). The cognitive behavioral therapy based on exposure and response prevention was performed on the subjects in nine individual sessions for 45 minutes for each experimental group. The data were analyzed using SPSS Inc., Chicago, IL; Version 16 by the multivariate analysis of covariance. Results: The results of multivariate analysis of covariance and Bonferroni post hoc tests showed that cognitive behavioral therapy based on exposure and response prevention were effective in decreasing OCD in the experimental groups compared to the control group (0.001≥ P). Bonferroni post hoc test showed that there was a significant difference between the scrupulosity group and the contamination group and control group on the obsession variable (0.05 < P). There was no significant difference between the contamination group and the scrupulosity group on the compulsion variable (0.15 < p). Conclusion: The findings suggest that cognitive behavioral therapy based on exposure and response prevention could help alleviate symptoms of obsessive-compulsive disorder in both religious and contamination OCD.

scholarly journals The Effectiveness of Mindfulness-based Cognitive Therapy on Marital Self-regulation, Marital Burnout and Self-criticism of Infertile Women

2020 ◽  
Vol 23 (4) ◽  
pp. 488-497
Author(s):  
Atefe Zarastvand ◽  
◽  
Taher Tizdast ◽  
Javad Khalatbari ◽  
Shahnam Abolghasemi ◽  
...  
Keyword(s):  
Cognitive Therapy ◽  
Self Regulation ◽  
Multivariable Analysis ◽  
Analysis Of Covariance ◽  
Control Group ◽  
Mazandaran Province ◽  
Statistical Population ◽  
Infertile Women ◽  
And Control ◽  
Experimental Group

Background and Aim: The purpose of this study was to determine the effectiveness of mindfulness-based cognitive therapy on marital self-regulation, marital burnout, and self-criticism of infertile women. Methods & Materials: This experimental study was conducted with a pretest-posttest design with the control group. The statistical population of this study included all the infertile women of Mazandaran Province, Iran, in 2018-2019. In this study, 30 infertile women were considered the sample size in the experimental group mindfulness-based cognitive therapy (of 15 infertile women) and control (15 infertile women). The experimental group underwent mindfulness-based cognitive therapy (10 sessions 60 minutes), but the control group received no training. To collect data, we used the marital self-regulation scale of Wilson and et al., the marital burnout scale of Pines, and the self-criticism scale of Thompson and Zuroff. Data analysis was performed in SPSS V. 24 with descriptive and inferential statistics (multivariable analysis of covariance). Ethical Considerations: This study with research ethical code IR.IAU.TON.REC.1397.030 was approved by the Research Ethics Committee at Islamic Azad University Tonekabon Branch. Results: The results showed that the scores of marital self-regulation of infertile women after mindfulness-based cognitive therapy in the experimental group significantly increased in comparison with the control group, and also marital burnout, and self-criticism scores were decreased (P<0.01). Conclusion: Therefore, it is suggested that counselors and therapists use mindfulness-based cognitive therapy to improve marital self-regulation, marital burnout, and self-criticism of infertile women.

scholarly journals Efficacy of the Addition of Celecoxib to Selective Serotonin Reuptake Inhibitors in Treating Obsessive–Compulsive Disorder: A Double-Blind Clinical Trial Study

2021 ◽  
Author(s):  
Najmeh Shahini ◽  
◽  
Ali Talaei ◽  
Mohammadreza Shalbafan ◽  
Farhad Faridhosseini ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Serotonin Reuptake ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Serotonin Reuptake Inhibitors ◽  
Cyclooxygenase Inhibitors ◽  
Selective Serotonin ◽  
Control Group ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Significant Difference

Purpose of the Study: Inflammatory processes in the brain play an important role in etiopathogenesis of Obsessive-Compulsive Disorder (OCD). Cyclooxygenase inhibitors such as celecoxib reduce the production of proinflammatory cytokines. This triple-blind study aimed to investigate the efficacy of the addition of Celecoxib to selective serotonin reuptake inhibitors in treating Obsessive–Compulsive Disorder (OCD) Ther Methods: Sixty patients who met the diagnostic and statistical manual of mental disorders criteria –fourth edition (DSM-IV) were recruited in the study for OCD screening by two psychiatrists to participate in the trial. The participants included 23 patients who received SSRIs and celecoxib (400 mg twice daily) and 22 patients in the control group that received SSRIs and placebo. At the beginning of the study, in weeks four, eight and 12, the patients were assessed by a psychiatrist using the Yale-Brown Obsessive Compulsive Scale (Y-BCOS). The Results: A significant difference was observed in the change of scores on the Yale–Brown Obsessive–Compulsive Scale (Y-BOCS) in week 12 compared with the onset of the study in two groups (t:-8.976, df:38, P:0.001). There was a significant difference between two groups in obsession (F:49.19, df:1, P≤0.001) and compulsion (F:13.78, df:1, P:0.001), and in obsessive compulsive disorder (F:57.25, df:1, P≤0.001) which was higher in Celecoxib group. The Conclusion: This study showed that adjuvant treatment with celecoxib can treat symptoms of OCD under treatment with SSRIs.

scholarly journals Adjunct Triptorelin in the Treatment of Obsessive-Compulsive Disorder in Clients Receiving Selective Serotonin Reuptake Inhibitors (SSRIs)

2021 ◽  
Author(s):  
Faezeh Nikzad ◽  
Seyed Alireza Sadjadi ◽  
Amir Hooshang Mohammadpour ◽  
Maliheh Ziaee ◽  
Fatemeh Behdani ◽  
...  
Keyword(s):  
Side Effects ◽  
Obsessive Compulsive Disorder ◽  
Serotonin Reuptake ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Intervention Group ◽  
Serotonin Reuptake Inhibitors ◽  
Control Group ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Significant Difference

Objective: Analog triptorelin is one of the effective agonists for the treatment of reproductive disorders, particularly prostate cancer. Due to results of previous studies, we hypothesized that obsessive-compulsive disorder (OCD can be effectively treated with the long-term administration of a gonadotropin-releasing hormone (GnRH) analog, namely triptorelin. The aim of this study was to evaluate the effectiveness of triptorelin injection in clients with OCD. Method: This randomized single-blind clinical trial was performed on 30 clients with OCD who had a Yale-Brown score of > 17 after 8 weeks of treatment. The participants were randomly assigned into two groups of triptorelin and placebo. The clients in the intervention group were treated with Selective serotonin reuptake inhibitors (SSRIs), including fluoxetine, in addition to triptorelin three times a month for at least 8 weeks. Clients in the control group received injection of distilled water as placebo three times in addition to the routine treatment. The outcome was evaluated by Yale-Brown OCD scale (Y-BOCS) at the baseline, as well as 4, 8, and, 20 weeks after the end of the treatment. Results: The mean scores of Y-BOCS in the intervention and control groups was 30.5 ±67.6 and 30.5 ±67.6, respectively, before intervention, indicating no significant difference between the two groups (P = 0.0.8). The comparison of Y-BOCS scores after the intervention showed a significant difference between the two groups in the scores 4 (P = 0.01), 8 (P < 0.005), and 20 (P < 0.005) weeks after the treatment. With regards to the side effects of the medicine, 6.7% (n = 1) of the clients in the control group developed headache and 66.7% (n = 10) had late period in intervention group. The results revealed a significant difference between the two groups in terms of side effects (P < 0.005). Conclusion: The results of this study showed triptorelin decreased the symptoms of OCD. The effectiveness of triptorelin in the treatment of symptoms in clients with OCD was confirmed in our study. However, due to the limited research addressing this domain, future studies are suggested to clarify this conclusion.

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