scholarly journals Relationship between Obsessive-compulsive Disorder and Overactive Bladder Syndrome

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Farzad Allameh ◽  
Mahtab Motamed ◽  
Morteza Fallah-Karkan ◽  
Mohammad Poury ◽  
Saba Faraji ◽  
...  

Background: Overactive bladder (OAB) syndrome correlates with mental disorders, especially depressive disorders and anxiety disorders, and less frequently obsessive-compulsive symptoms, and occurs mostly in older people. Obsessive-compulsive disorder (OCD) is more frequent in OAB patients. Most OCD people are diagnosed at the age of about 19, typically with an earlier age of onset in boys than in girls, but the onset after age 35 does occur less frequently. Objectives: This study aimed to evaluate the relationship between OCD and OAB. Methods: In this case-control study, 1,160 cases who were over 18 years old who were referred to the urodynamic clinic of Shohada-e-Tajrish center from June 2013 to February 2018 in Tehran, Iran, enrolled of whom 580 were considered the control group who were non-OAB patients, and 580 subjects were considered the case group who were OAB patients. The diagnosis of OAB was confirmed by a single urologist. All cases had detrusor overactivity (DO) in urodynamic study (UDS). The OAB-validated 8-questionnaire screen test (OAB-V8) was conducted, and the diagnosis of OCD was confirmed by a single psychiatrist according to DSM-5 criteria. Moreover, the Yale-Brown questionnaire was completed for each patient to rate the severity of OCD symptoms. Results: About the Yale-Brown Obsessive-compulsive Scale (Y-BOCS) total score, there is a significant difference between patients with obsessive traits and the control group (P < 0.001). OCD scores were significantly higher in the OAB group compared to the control group (P < 0.001). Logistic regression analysis showed that the population of the studied patients with OAB was more probable to have OCD than non-OAB control subjects in aged classified groups (OR: 6.23; P < 0.001). Conclusions: The findings of this study showed that OAB patients reported higher obsessive-compulsive scores (Y-BOCS) compared to the controls. There is an independent correlation between OCD and OAB. However, the linkage between OCD and OAB justifies the need for more research.

Author(s):  
Sarah Alaa Mohsen ◽  
Fatma Ahmed El Deeb ◽  
Ehab Sayed Ramadan ◽  
Mai Abd El-Raouf Eissa

Background: Obsessive compulsive disorder (OCD) is a common and potentially debilitating disorder. Neuropsychological assessment provides unique complementary information that is critical for evaluating higher cortical abilities. This study aimed to assess the neuropsychological functions in OCD patients which can then point to the brain structures or pathways and to study the correlation between these assessments and different clinical variables. Methods: This cross-sectional case control study had included sixty patients who were divided into two groups, Group I: thirty OCD patients diagnosed by DSM-IV and Group II: thirty healthy controls who were recruited from the community, matched with patients’ age, gender, and education. Results: The age of onset in our study was 19.13 ± 0.35 years, the mean duration was 7.44 ± 3.88 years, 40% of the studied cases had severe OCD symptoms and 33.3% of them were compulsive cleaners. There was a high significant difference between the two groups regarding WCST in favor of the control group. There was a high significant difference between the two groups regarding ROCF where the control group showed better results than the OCD patients. Conclusions: Neuropsychological test performance remains an informative and objective means of investigation, especially when applied to psychiatric disorders. The executive functions in OCD patients were impaired in comparison to the normal study subjects.


2020 ◽  
Vol 20 (2) ◽  
pp. 101-120
Author(s):  
Ayça Aktaç Gürbüz ◽  
Orçun YORULMAZ ◽  
Gülşah DURNA

Scientific research into the reduction of stigmatization, particularly related to specific problems such as Obsessive-Compulsive Disorder (OCD), is scarce. In the present study, we examine the impact of a video-based antistigma intervention program for OCD in a pretest-posttest control group research. After being randomly assigned to either an intervention (n= 101) or control group (n= 96), the participants reported their attitudes on a hypothetical case vignette before and after OCD vs. Multiple Sclerosis (MS) videos, and again six months later as a follow up assessment. The mixed design analyses for the group comparisons indicated that although there was no significant difference in the measures of the control group, the participants watching the anti-stigma OCD video, in which the focus was psychoeducation and interaction strategies, reported significantly lower scores on social distances and negative beliefs for the case vignettes they read, and this difference was maintained six months later. Then, the present results indicate the effectiveness of our anti-stigma intervention program for OCD. Interventions to reduce stigmatization can also be viewed as effective tools for changing the attitudes of people toward OCD, although further research and applications are needed related to specific disorders if a longlasting impact is to be achieved.


Author(s):  
Hiva Mahmoodi ◽  
Hasan Gharibi ◽  
Mohamad Khaledian

The aim of this study was the investigation of the efficacy of the Cognitive and Exposure therapy on the treatment of obsessive- compulsive disorder. This study is experimental expanded with multiple group pre-test, post-test. The statistical population of this study are included all patients with OCD, referred to clinical centers, hospitals and private clinics and counseling centers in Saghez and Boukan citiesat the age of 40-20 years. The statistical sample of this study is included 45 patientswith Obsessive Compulsive Disorder, Who were selected randomly. Cognitive therapy was administered for the first experimental group and the second experimental group receives exposure therapy while the control group received no treatment. Subscales Madsly questionnaire was usedfor data gathering for OCD. For data analysis, multivariate analysis of covariance (MANCOVA) and least significant difference test to compare scores differences between pretest - posttest variables in the experimental and control groups was used. Findings showed that Cognitive and Aversion Therapy on the control group has a significant impact on the improvement of obsession, check out, washing, slowness and obsessive doubts. The results showed that Whittal Cognitive Therapy more impact on the reduction of obsessions in comparsion with Exposure therapy.


Author(s):  
Faezeh Keshvarifard ◽  
Mehdi Rafiei ◽  
Susan Sadeghian ◽  
Hadi Farhadi ◽  
Nafiseh Shirani

Introduction: The Malocclusion or misalignment of teeth affects not only oral function but also facial esthetics and the psychological well-being of patients. In addition, obsessive-compulsive disorder is a psychological disorder associated with anxiety involving 2-2.5% of the population during their life. This study aimed to assess the severity of obsessive-compulsive disorder in patients having class I malocclusion with crowding. Materials & Methods: In this case-control trial, Using the Yale-Brown questionnaire, female patients with 18-22 years old of ages having class I crowding malocclusion and referring to orthodontic department of Azad Dental school enrolled in the trial as the case group (n = 60). The participants with similar malocclusion without reference for orthodontic treatments followed up as the control group (n = 60). The obtained data by Yale-Brown questionnaire classified the obsessive-compulsive disorder in the participants into four groups of mild, fairly mild, moderate and severe levels. The results of the two groups were analyzed using the Chi-square test (p value < 0.05). Results: In malocclusion patients referring for orthodontic treatments, 19 (31.7%) had mild OCD; 7 (11.7%) had fairly mild OCD; 23 (38.3%) had moderate OCD and 11 (18.3%) showed severe OCD. These values were 28 (46.7%); 12 (20.0%); 15 (25.0%) and 5 (8.3%) for malocclusion patients not referring for orthodontic patients respectively. No significant differences were found among 2 groups regarding severity of OCD (p value = 0.07). Conclusion: In terms of the severity of OCD, there were no significant variations between malocclusion patients with and without referring for orthodontic treatments.


2016 ◽  
Vol 8 (3) ◽  
pp. 135-141 ◽  
Author(s):  
Hande Ayraler Taner ◽  
Rabet Gozil ◽  
Elvan Iseri ◽  
Ece Buru ◽  
Meltem Bahcelioglu

Objectives: The ratio of the index finger (2D) to the ring finger (4D) is different in males and females. This ratio (2D:4D) has been investigated in a variety of diseases, including autism, schizophrenia, attention deficit hyperactivity disorder, and anxiety disorders. The aim of this study was to investigate the 2D:4D ratio in children and adolescents with obsessive compulsive disorder and to detect any differences in that ratio between participants with obsessive compulsive disorder and a healthy control Material-Methods: The study included 30 children and adolescents diagnosed with obsessive compulsive disorder between ages 7-17 and 90 age-sex matched controls. After the psychiatric evaluations;  finger lenghts were measured with a digital compass. Main results: Girls with obsessive compulsive disorder had greater 2D:4D ratios in their right and left hands than the control group. Although there was no statistically significant difference, the 2D:4D ratio in the right hand was greater in the obsessive compulsive disorder group than in the control group. Conclusion: With relation to obsessive compulsive disorder, some differences were detected in 2D:4D ratios of patients  with obsessive compulsive disorder and control groups but there were no statistically significant results except for that of girls with obsessive compulsive disorder. Further studies are needed to fully understand the relationship between obsessive compulsive disorder and the 2D:4D ratio. Objetivos: La proporción entre los dedos índice y anular es diferente en las mujeres y en los hombres. Esta proporción ha sido estudiada en varias enfermedades como el trastorno de ansiedad, el trastorno de la concentración y la hiperactividad. El objetivo de este estudio era investigar la proporción entre los dedos de índice y anular en los niños y adolescentes que tienen trastorno obsesivo-compulsivo y determinar si existía alguna diferencia entre los participantes con trastorno obsesivo-compulsivo y los del grupo sano. Material y métodos: En el estudio fueron incluidos 30 niños y adolescentes que tenían entre 7 y 17 años de edad con trastorno obsesivo-compulsivo y 90 individuos sanos de igual edad y sexo como el grupo control. Después de las evaluaciones psiquiátricas, la longitud de los dedos fue medida con calibre digital. Resultados: Las niñas y adolescentes con trastorno obsesivo-compulsivo tenían una proporción mayor entre los dedos índice y anular en las manos derechas e izquierdas que el grupo control. Aunque no había una diferencia estadísticamente significativa, la proporción entre los dedos índice y anular en la mano derecha era más grande en el grupo de trastorno obsesivo-compulsivo que el grupo control. Conclusiones: Algunas diferencias fueron detectadas en la proporción entre los dedos índice y anular en los pacientes con trastorno obsesivo-compulsivo y los del grupo control, pero no había resultados estadísticamente significativos excepto las niñas y adolescentes con trastorno obsesivo-compulsivo. Se requieren más estudios para entender completamente la relación entre el trastorno obsesivo-compulsivo y la proporción entre los dedos índice y anular. 


1993 ◽  
Vol 8 (4) ◽  
pp. 219-221 ◽  
Author(s):  
D Cassano ◽  
G Del Buono ◽  
F Catapano

SummaryWe administered the Personality Disorder Examination (PDE) to 31 patients meeting DSM III criteria for obsessive-compulsive disorder (OCD) and to an age-and sex-matched healthy control group. Seventeen patients (54.8%) and four controls (12.9%) met criteria for one or more DSM III Axis II diagnoses. The most frequent Axis II diagnoses in patients were avoidant, passive-aggressive and compulsive personality disorder. Compulsive personality disorder was diagnosed in 6 OCD patients (19.3%). The prevalence of this disorder did not change according to sex, age of onset or duration of OCD, and severity of obsessive-compulsive symptoms.


Author(s):  
Farzad Farhoodi ◽  
Javad Salehi Fadardi ◽  
Ali Ghanaie Chamanabad ◽  
Seyed Hamid Mirhoseini

Introduction: The aim of the present study was to compare the effectiveness of cognitive behavior therapy based on exposure and response prevention on the patients with contamination obsessive-compulsive disorder (OCD) and scrupulosity. Methods: The method was semi-experimental pretest-posttest design by control group. Sixty OCD participants who were suffering from scrupulosity and contamination OCD were diagnosed by means of diagnostic interviewing, Yale-Brown Obsessive-Compulsive Scale and Penn inventory of scrupulosity. They were selected through convenience sampling method and were assigned in two experimental groups and one control group (each group 20). The cognitive behavioral therapy based on exposure and response prevention was performed on the subjects in nine individual sessions for 45 minutes for each experimental group. The data were analyzed using SPSS Inc., Chicago, IL; Version 16 by the multivariate analysis of covariance. Results: The results of multivariate analysis of covariance and Bonferroni post hoc tests showed that cognitive behavioral therapy based on exposure and response prevention were effective in decreasing OCD in the experimental groups compared to the control group (0.001≥ P). Bonferroni post hoc test showed that there was a significant difference between the scrupulosity group and the contamination group and control group on the obsession variable (0.05 < P). There was no significant difference between the contamination group and the scrupulosity group on the compulsion variable (0.15 < p). Conclusion: The findings suggest that cognitive behavioral therapy based on exposure and response prevention could help alleviate symptoms of obsessive-compulsive disorder in both religious and contamination OCD.


2021 ◽  
Author(s):  
Pedram Ataee ◽  
Hadi Badiee ◽  
Soleiman Mohammadzadeh ◽  
Borhan Moradveisi ◽  
Daem Roshani ◽  
...  

Chronic constipation is one of the most common problems in children. It can cause anxiety and psychological problems in patients and parents. The purpose of this study was to investigate the relationship between obsessive-compulsive disorders (OCD) in children with chronic functional constipation. This is a case-control study performed at the gastroenterology clinic of Besat Hospital Sanandaj for one year. The children aged 7-14-year-old with chronic functional constipation were selected as a case group, and the healthy children were recruited as a control group, who referred for growth control. Then, the Maudsley questionnaire for obsessive-compulsive disorders was completed by a trained assistant. With this questionnaire, the presence or absence of OCD and its type can be determined. Forty-three children were selected as the case group and sixty-seven children as the control group. The mean age of the case and control group was 9.3±1.5 and 8.8±1.6 years, respectively. Based on the results, there was a significant difference between the groups in terms of checking, cleaning, slowness, doubting, and total obsessive score (P˂0.05). Therefore, all five types of obsessive-compulsive disorder in the case group were greater than the control group. Obsessive-compulsive disorders were more common in children with functional constipation, and the total obsessive score in these children than the healthy children was a significant difference.


Author(s):  
Najmeh Shahini ◽  
◽  
Ali Talaei ◽  
Mohammadreza Shalbafan ◽  
Farhad Faridhosseini ◽  
...  

Purpose of the Study: Inflammatory processes in the brain play an important role in etiopathogenesis of Obsessive-Compulsive Disorder (OCD). Cyclooxygenase inhibitors such as celecoxib reduce the production of proinflammatory cytokines. This triple-blind study aimed to investigate the efficacy of the addition of Celecoxib to selective serotonin reuptake inhibitors in treating Obsessive–Compulsive Disorder (OCD) Ther Methods: Sixty patients who met the diagnostic and statistical manual of mental disorders criteria –fourth edition (DSM-IV) were recruited in the study for OCD screening by two psychiatrists to participate in the trial. The participants included 23 patients who received SSRIs and celecoxib (400 mg twice daily) and 22 patients in the control group that received SSRIs and placebo. At the beginning of the study, in weeks four, eight and 12, the patients were assessed by a psychiatrist using the Yale-Brown Obsessive Compulsive Scale (Y-BCOS). The Results: A significant difference was observed in the change of scores on the Yale–Brown Obsessive–Compulsive Scale (Y-BOCS) in week 12 compared with the onset of the study in two groups (t:-8.976, df:38, P:0.001). There was a significant difference between two groups in obsession (F:49.19, df:1, P≤0.001) and compulsion (F:13.78, df:1, P:0.001), and in obsessive compulsive disorder (F:57.25, df:1, P≤0.001) which was higher in Celecoxib group. The Conclusion: This study showed that adjuvant treatment with celecoxib can treat symptoms of OCD under treatment with SSRIs.


Author(s):  
Faezeh Nikzad ◽  
Seyed Alireza Sadjadi ◽  
Amir Hooshang Mohammadpour ◽  
Maliheh Ziaee ◽  
Fatemeh Behdani ◽  
...  

Objective: Analog triptorelin is one of the effective agonists for the treatment of reproductive disorders, particularly prostate cancer. Due to results of previous studies, we hypothesized that obsessive-compulsive disorder (OCD can be effectively treated with the long-term administration of a gonadotropin-releasing hormone (GnRH) analog, namely triptorelin. The aim of this study was to evaluate the effectiveness of triptorelin injection in clients with OCD. Method: This randomized single-blind clinical trial was performed on 30 clients with OCD who had a Yale-Brown score of > 17 after 8 weeks of treatment. The participants were randomly assigned into two groups of triptorelin and placebo. The clients in the intervention group were treated with Selective serotonin reuptake inhibitors (SSRIs), including fluoxetine, in addition to triptorelin three times a month for at least 8 weeks. Clients in the control group received injection of distilled water as placebo three times in addition to the routine treatment. The outcome was evaluated by Yale-Brown OCD scale (Y-BOCS) at the baseline, as well as 4, 8, and, 20 weeks after the end of the treatment. Results: The mean scores of Y-BOCS in the intervention and control groups was 30.5 ±67.6 and 30.5 ±67.6, respectively, before intervention, indicating no significant difference between the two groups (P = 0.0.8). The comparison of Y-BOCS scores after the intervention showed a significant difference between the two groups in the scores 4 (P = 0.01), 8 (P < 0.005), and 20 (P < 0.005) weeks after the treatment. With regards to the side effects of the medicine, 6.7% (n = 1) of the clients in the control group developed headache and 66.7% (n = 10) had late period in intervention group. The results revealed a significant difference between the two groups in terms of side effects (P < 0.005). Conclusion: The results of this study showed triptorelin decreased the symptoms of OCD. The effectiveness of triptorelin in the treatment of symptoms in clients with OCD was confirmed in our study. However, due to the limited research addressing this domain, future studies are suggested to clarify this conclusion.


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