scholarly journals A questionnaire based study on the knowledge, attitude and the practices of pharmacovigilance among the postgraduate students at a tertiary care hospital in south India

Author(s):  
Chiranjeevi Uday Kumar ◽  
G. Harijagannadha Rao ◽  
G. Vasavi

Background: Adverse drug reactions (ADRs) are common cause of morbidity in the practice of medicine. Pharmacovigilance is the science of detection, assessment and understanding and prevention of adverse effects or any drug related problems. Post graduates are perhaps the first to notice ADRs in outpatient/inpatient setup as they spend most of the time bedside. Thus, this study was conducted to assess the knowledge, attitude and practices (KAP) of postgraduates about Pharmacovigilance.Methods: A prevalidated and pretested questionnaire with 20 questions related to KAP of pharmacovigilance is administered to postgraduate students after obtaining their consent. All the completed and returned questionnaires were analysed for results using appropriate statistics.Results: 180 pretested questionnaires were distributed among postgraduates out of which, 122 were returned from postgraduates of all major medical and surgical allied departments. 90.2 % defined pharmacovigilance correctly, 83.6% thought reporting ADRs is a professional obligation, while only 65.6% knew regarding the existence of national pharmacovigilance program. 58.4% have experienced ADRs, of which only 24.6% reported ADR to pharmacovigilance centre. Major reasons for under reporting are lack of time to report and difficulty to decide whether ADR has occurred or not.Conclusions: In this study, the knowledge and attitude related to Pharmacovigilance is good amongst postgraduates, but practical implementation in reporting of ADRs is poor. Sensitization programs on pharmacovigilance practice in tertiary care hospitals and regular review meetings to ensure ADR reporting to pharmacovigilance centre will strengthen the health care setup.

Author(s):  
Mamatha N. ◽  
Reshma Nadaf

Background: The objective of the study was to evaluate the knowledge and attitude towards pharmacovigilance and adverse drug reaction (ADR) reporting among the undergraduates, interns and postgraduate students.Methods: This was a cross sectional study done among the undergraduates, interns and post graduate medical students at Karnataka Institute of Medical Sciences, Hubballi using a pre-validated questionnaire that included 20 questions to evaluate the participants knowledge and perception of ADR and pharmacovigilance. The questionnaire was distributed to the participants (n=606) after taking their informed consent. The data was compiled and evaluated as percentages.Results: About 52% of the participants were aware of pharmacovigilance and 38.7% knew about the purpose of pharmacovigilance programme of India. 51% of the participants have experienced ADRs during their professional practice out of which 23% have reported to the pharmacovigilance centre. The most common barrier for under-reporting was lack of time to report ADR among 34% of the participants. 31% of the participants felt that managing patient was more important than reporting ADRs. 29% of the participants gave the reason as lack of access to ADR reporting forms. 25% of the participants had difficulty to decide whether ADR has occurred or not.Conclusions: Our study strongly suggests a greater need to create an awareness among undergraduate medical students, interns and postgraduate students to improve the reporting of ADRs.


Author(s):  
Qaiser Jahan ◽  
K. Pallavi ◽  
R. Hamshika ◽  
Varun Talla ◽  
Jupally Venkateshwar Rao ◽  
...  

Background: Improper drug usages expose patients to drug-related problems (DRPs) and can be the cause of patient morbidity and even mortality, especially frequent in hospitalized patients and pediatric groups. Objective: The objective of the present study was to identify and assess the drug-related problems in the pediatric department of tertiary care hospitals. Methods: The cross-sectional, observational study was carried out for six months included pediatric in-patients of age ≤15 years of either gender in pediatric units of tertiary care hospitals of India. The enrolled pediatric patients were observed for any drug-related problem that were further recorded and classified using the DRP registration format taken from Cipolle et al. The assessment of therapy was done by using positional statements from standard organizations and guidelines. Main outcome measure: Incidences of drug-related problems and their assessment and root cause analysis. Results: A total of 970 DRPs were identified in 296 patients, with an overall incidence of 49.3%. The incidence of DRPs was maximum in the age group of 2-12 years of children (51.2%). Patients who took six or more drugs were around eight (OR:8.41 , 95% CI: 5.22 to 13.55) times more likely to have DRPs compared to those patients who took less than six drugs. The incidences of DRPs were more in patients who were hospitalized for ≥ 7 days. Conclusion: The present study revealed significantly higher incidences of DRPs in hospitalized pediatric patients necessitating the involvement of clinical pharmacists in the pediatric department of tertiary care hospitals.


Author(s):  
Fatima Fakir Musharraf ◽  
Anooja Rani

Pakistan has nearly 200 million people, of which almost 20 million people live in Karachi, which has 17 tertiary care hospitals, and it is no secret that they are overburdened (1). Despite the healthcare workers’ competency, several issues hinder administering proper care in a tertiary healthcare setup. Firstly, spatial distancing-spatial access to facilities within a hospital also proves a challenge for patients. Patients have little idea regarding specific departments in a large tertiary care hospital due to low literacy rates compounded with a lack of health literacy. At times many patients have reportedly circled the hospital twice and can still not find their desired specialist. A study conducted in Delhi that closely matches Karachi in demographics suggested that patients with one-time visits to secondary care facilities had lower follow-up rates than those who were more familiar with the system (2). Patients may take time to acclimatize to healthcare setup when visiting as first-timers, and if found too challenging to adapt, they may not make an effort again. Unsurprisingly, this renders many facilities- the administration spends, sometimes a fortune, procuring- useless. Continuous...


2020 ◽  
Vol 5 (2) ◽  
pp. 1055-1059
Author(s):  
Raj Deb Mahato ◽  
Amit Deo ◽  
Hanoon Pokharel

Introduction: Cervical cancer is the most common Gynaecological cancer in Nepal which is preventable if appropriate screening and prevention measures are employed. Considerable reduction in cervical cancer incidence and cervical cancer related deaths can be achieved by effective screening. However, lack of knowledge and awareness can result in underutilization of the preventive measures.  Objectives: The objective of this study was to assess the knowledge and attitude regarding cervical cancer screening in women visiting Obstetrics and Gynaecology OPD at tertiary care Hospital in Eastern Nepal.  Methodology: A cross-sectional questionnaire-based study was conducted in Obstetrics and Gynaecology outpatient department of Birat Medical College Teaching Hospital from 1 January 2019 to 31 December 2019. Women were enrolled in the study by convenient sampling methods. Structured questionnaire was used to collect the data. The collected data was entered in Microsoft excel and analyzed by using SPSS version 22.  Results: Among 374 participants, the mean age was 31.13 years. More than three fourth (89.6%) of participants were literate. Regarding occupation, 89.8% of participants were housewives, and 82.9 % of participants were married. As per the findings, only 43.27 % of participants i.e. less than the mean, had adequate knowledge of cervical cancer and its screening. 65.50 % of participants had a negative attitude towards cervical cancer screening. Literate participants had good knowledge and positive attitude regarding cervical cancer screening than illiterate participants (P value less than 0.05).  Conclusion Considerable proportions of participants had inadequate knowledge and negative attitude regarding cervical cancer screening in Gynaecological patients visiting tertiary care Hospital in Eastern Nepal.


2019 ◽  
Vol 26 (02) ◽  
Author(s):  
Shahid Iqbal ◽  
Naeemullah Bullo ◽  
Dileep Kumar ◽  
Suneel Kumar ◽  
Munir Afzal ◽  
...  

Objectives: To determine the frequency of various clinical features of Guillian Barre Syndrome in patients presenting to a tertiary care hospital in Karachi. Study Design: Descriptive study. Period: July 2015 to December 2015. Setting: Tertiary care hospitals of Karachi. Material & Methods: Seventy five diagnosed case of GBS who fulfill the inclusion criteria irrespective of gender included in the study after informed consent. Data was collected on preformed proforma. Detailed history, physical examination was done on each patient, diagnosis was confirmed on NCV & EMGs.  Data analysis procedure was done with the help of SPSS version 16. Mean±SD was calculated for age of the patient and duration of clinical features. Frequency and percentages were calculated for different clinical features. Stratification was done with respect to age, gender and duration of clinical features to control effect modifiers in the study. Results: Mean age was 43.96±14.22 (ranging from 15 to 70) years, among 75 patients 51(68%) were male & 24(32%) were female, majority of patients (34) were >50 years of age, 45.3% of patients had pain in extremities; pain in back was reported by 49.3%. Dysphagia in 80%, Ophthalmoplegia in 20% and Dysarthria in 16% of patients Respiratory failure was prevalent in 34.7% patients. Sinus tachycardia occurred in 49.3%, Sinus bradycardia 14.7% patients and 20% patients had urinary dysfunction. Constipation was also a predominant feature affecting 80% of patients. Conclusion: We found that GBS occurred at all ages and was more common in males. There are various clinical features of GBS along with flaccid limbs weakness clinical features observed & these should be address promptly for better outcome.


Author(s):  
Fahmida Parveen ◽  
Samia Aijaz ◽  
Sakeena Ahmed Memon ◽  
Hina Akmal

Objective: To determine the awareness, practice, knowledge and attitude toward the Covid 19 among antenatal patients at tertiary care Hospital. Methodology: This was a cross sectional survey which was conducted at Gynae and obstetrics department at Liaquat University Hospital Hyderabad. Study duration was six months from March 2020 to August 2020. All the pregnant women visited antenatal clinic age 18 to 40 years and either of parity were included. All the pregnant females were interviewed by using a questioner regarding awareness, attitude and practice toward the Covid19 after taking informed consent. All the data was recorded via study proforma. Data was analyzed by using SPSS version 20. Results: Total 173 pregnant women were interview regarding COVID-19, their mean age was 29.34+13.12 years. Most of the women were presented with age between 18 to 37 years. 70.5% were multigravida and majority of women were uneducated. Mostly women 75.1% had heard regarding. 72.8% women said, they should stay at home and 25.4% said should wear the face mask, while 38.7% said the women should inform the health care provider in advance before visit to Hospital if developed any symptom. Most of the women had good knowledge and attitude, while preventive practice was found to be unsatisfactory. Conclusion: knowledge and awareness were found to adequate; while preventive practice has been observed unsatisfactory among pregnant women during antenatal clinic. Clinicians should provide appropriate counseling to reassure and elucidate doubts of pregnancy females regarding COVID-19 during antenatal visits.


Author(s):  
Kirti Saxena ◽  
Chaitali Tailor ◽  
Chaitali Mehta ◽  
Paresh Gajera ◽  
S. K. Srivastava

Background: The adverse drug reactions (ADRs) reported to pharmacovigilance centre in tertiary care hospital was analysed to find out the incidence and causality.Methods: This was a retrospective study to analyse the ADR reported at pharmacovigilance centre after ethical clearance from Institutional Ethic Committee (IEC). ADR data were analysed and ADRs were categorized as department-wise, system affected and causative drug. The causality of each ADR was assessed by WHO-UMC scale.Results: The majority of patients who had suffered from ADRs were between 19-64 years of age (94.2%) and male patients (58.6%) were affected more than female (41.4%). Pulmonary medicine department has reported highest number of ADR followed by dermatology department. Skin (46.5%) was most affected system followed by gastrointestinal (30.45%), CNS (21.26%), respiratory (9.0%) and remaining systems. Rifampicin (13.79%) shows the largest numbers of ADR followed by zidovudine (13.21%), nevirapine (12.64%) and diclofenac sodium (8.0%). The maximum ADRs reported were probable (94.8%) followed by possible (5.2%).Conclusions: In conclusion, the skin was most affected system followed by gastrointestinal, central nervous and respiratory system. Rifampicin has caused maximum ADRs followed by zidovudine, nevirapine and diclofenac sodium. The causality analyses showed that majority of ADRs were probable (94.8%) while remaining falls in possible (5.2%) category.


Sign in / Sign up

Export Citation Format

Share Document