scholarly journals A pharmacoepidemiology study of local fungal infections in skin and venereal diseases outpatient department of a rural tertiary care hospital

2020 ◽  
Vol 9 (4) ◽  
pp. 616
Author(s):  
Preety Bansal ◽  
Seema Baishnab
Keyword(s):  
Fungal Infection ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Antifungal Drugs ◽  
Care Hospital ◽  
Dermatology Department ◽  
Number Of Patients ◽  
Common Skin ◽  
Cutaneous Fungal Infection ◽  
Number Of Males

Background: Fungal infections of the skin were the 4th most common skin disease in 2010 affecting 984 million people. An estimated 20-25% of the world’s population has some form of fungal infection. Dermatophytes are fungi that cause superficial infections of the skin, commonly referred to as tinea infections.Methods: This was a prospective and an observational study conducted from February 2018 to January 2019 in Dermatology Department. Prescriptions included all newly diagnosed patients with cutaneous fungal infection of both sex who attended dermatology OPD. Factors considered were sociodemographic parameters, the disease encountered and number of patients in each group and number of patients who received antifungal therapy (oral and topical) etc.Results: 1000 prescriptions were analysed of patients between 18 to 65 years of age with cutaneous fungal infections. There were a greater number of males (57.4%) than females (42.6%). The average number of antifungal drugs prescribed per prescription was 2.33. Majority of the patients were prescribed itraconazole (82.30%) followed by terbinafine (9.70%) and fluconazole (8.0%).Conclusions: The most common oral antifungal drug used was itraconazole. Ketoconazole and Terbinafine were the most commonly used topical agents respectively.

scholarly journals A study on the prescription pattern of antifungal drugs in the Dermatology Department of a tertiary care teaching hospital in Southern Kerala

2018 ◽  
Vol 8 (1) ◽  
pp. 100
Author(s):  
Parvathy Gopimohan ◽  
Sudha M. J. ◽  
Rathish T. Pillai ◽  
Ramani P. T.
Keyword(s):  
Fungal Infection ◽  
Tertiary Care ◽  
Cost Effective ◽  
Antifungal Drugs ◽  
Fixed Dose ◽  
Dermatology Department ◽  
Prescription Pattern ◽  
Number Of Patients ◽  
Dose Combination ◽  
Cutaneous Fungal Infection

Background: Skin disorders form 2% of total Out Patient Department consultations worldwide. But no such data is available from India. Studying prescription pattern is a component of medical audit that help prescribers to provide rational and cost-effective medical care. This study is about the prescription pattern of antifungals in this institution and will help in developing local policies for appropriate use of antifungal drugs. The objective was to study the prescription pattern of antifungals in dermatological diseases.Methods: This is a retrospective study conducted from 1st June 2017 to 30th November 2017 in Dermatology Department. Prescriptions included all newly diagnosed patients with cutaneous fungal infection of both sex who attended Dermatology OPD. Factors considered were sociodemographic parameters, number of patients with combination and monotherapy, number of single topical agents and Fixed Dose Combination (FDC) details of prescribing indicators.Results: 1500 prescriptions were analysed; 500 prescriptions were of fungal infection. 40.2% of the patients were in 18-35 years age group. There were a greater number of males (59.6%) than females (40.4%).Conclusions: The most common oral antifungal used was fluconazole. Terbinafine and clotrimazole were the most commonly used topical agents.

scholarly journals Implementation of Pharmacist-driven Antifungal Stewardship Program in A Tertiary Care Hospital

2021 ◽  
Author(s):  
Emre Kara ◽  
Gokhan Metan ◽  
Aygin Bayraktar-Ekincioglu ◽  
Dolunay Gulmez ◽  
Sevtap Arikan-Akdagli ◽  
...  
Keyword(s):  
Antifungal Therapy ◽  
Clinical Pharmacist ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Antifungal Drugs ◽  
Care Hospital ◽  
Antifungal Stewardship ◽  
Inappropriate Use ◽  
Stewardship Program ◽  
Antifungal Use

Objectives: Antifungal stewardship (AFS) is recommended to reduce the inappropriate use of antifungal drugs. In this study, the role of AFS in providing appropriate antifungal therapy was evaluated. Methods: This study included three periods as observation, feedback/education, and daily AFS activities. In observation period, the use of systemic antifungals was evaluated for a baseline measurement of appropriateness. In second period, monthly meetings were organized to provide feedback and education to physicians regarding antifungal therapy and the rate of adherence to the clinical guidelines. In final period, a clinical pharmacist participated in daily ward rounds to evaluate appropriateness of the antifungal therapy. A scoring system for appropriateness was used for comparison between the three periods. Results: Four hundred and eighteen episodes of antifungal therapy were evaluated. Baseline demographics of patients were similar in all three periods for age, gender, and the number of comorbidities. The indications for antifungal use were for prophylaxis in 22.7%, Candida infections in 58.6%, and invasive mould infections in 18.7%. During the third period, 157 (78.9%) recommendations were made and 151 (96.2%) were accepted. The overall appropriateness of antifungal use increased significantly for prophylaxis (30.8%, 17.9%, 46.3%, p=0.046) and treatment of fungal diseases (27.8%, 32.4%, 71.9%, p<0.001) between the first, second and third periods, respectively. A 30-day mortality was not significantly changed between the three periods (19%, 15.6% and 27.5%; p=0.050). Conclusions: Appropriateness in antifungal therapy can be augmented by the integration of an AFS program. A team-based evaluation of fungal infections and assessment of patients by a clinical pharmacist with a therapeutic perspective may help to increase the quality of antifungal therapy.

scholarly journals Epidemiological profile of patients presenting to dermatology department of a tertiary care hospital during nationwide lockdown due to COVID-19: a retrospective study from north India

2021 ◽  
Vol 9 (2) ◽  
pp. 443
Author(s):  
Faizan Younus Shah ◽  
Irfan Tasaduq ◽  
Yaqzata Bashir ◽  
Ifrah Shafat Kitab ◽  
Aaqib Aslam Shah ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Hair Loss ◽  
Seborrheic Dermatitis ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Dermatology Department ◽  
Female Pattern Hair Loss ◽  
Number Of Patients ◽  
Male Pattern

Background: The COVID-19 pandemic has seen an unprecedented lockdown with restrictions on human movement and interaction, imposed throughout the world to contain the spread of the disease. This gave us the unique opportunity to study the pattern of patients presenting to the dermatology out-patient department during this period.Methods: The study was a retrospective observational study involving the assessment of patient records from 25th March 2020 to 7th June 2020. This period corresponds to the duration of strictly imposed nationwide lockdown which was relaxed with phased resumption from 8th June 2020, termed as unlock 1.Results: A decrease in the absolute as well as proportional number of patients was seen in majority of the cases with a statistically significant proportional decline being seen in cases of allergic contact dermatitis (p-value =0.007), acne (p value <0.001), male pattern hair loss (p value <0.001) and female pattern hair loss (p value <0.001), verrucae (p value=0.01), seborrheic dermatitis (p value <0.001), ephelids (p value <0.001), melasma (p value<0.001), post-inflammatory hyperpigmentation (p value=0.006). However, there were certain disorders whose proportionate representation increased significantly during the lockdown period contrary to prevalent belief. These disorders included urticaria (p value <0.001), herpes zoster (p value <0.001), scabies (p value =0.01), generalized pruritus (p value <0.001) and prurigo (p value <0.001).Conclusions: Disorders like acne, male pattern hair loss, female pattern hair loss, verrucae, seborrheic dermatitis, ephelids, melasma and post-inflammatory hyperpigmentation which do not cause significant morbidity showed a significant decrease in proportional representation. The proportionate representation of disorders like urticaria, herpes zoster, scabies, generalized pruritus and prurigo increased significantly during the lockdown period.

scholarly journals The prevalence of skin and venereal diseases among the geriatric patients attending in a tertiary care Hospital in Dhaka, Bangladesh

2018 ◽  
Vol 18 (1) ◽  
pp. 130-135
Author(s):  
Mohd Nurul Alam ◽  
Md Anwar Husain ◽  
Ayesha Siddiqua ◽  
Zahir Uddin Mohammad Babar ◽  
Md Rashidul Hasan
Keyword(s):  
Fungal Infection ◽  
Geriatric Patients ◽  
Viral Infections ◽  
Tertiary Care Hospital ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Medical Science ◽  
Care Hospital ◽  
Venereal Diseases ◽  
Eczematous Dermatitis

Background: The prevalence of skin and venereal diseases among geriatric populations generally differ in different countries and within various regions of a country depending upon social, economic, racial & environmental factor. The morbidity in elderly associated with skin and venereal diseases makes them an important public health problem. Very scanty literature was found on this geriatric problem in our country which is either disease based, community based or specified population group based. Objective: To assess the dermatological & venereal complaints of the elderly attending a dermatology outpatient department in a tertiary care hospital. Materials and Methods: We retrospectively analyzed a total of 1303 geriatric patients who were 60 years and above and came to the OPD of dermatology & venereology department of Ibn Sina Medical College Hospital, Dhaka, Bangladesh, over a period of 3½ year from January, 2014 to June, 2017. Data were collected on special proforma and analyzed with appropriate method. Results: Among 1303 patients 676 (51.88%) were male and 627 (48.12%) were female and most of the patients belonged to the age group 60-69 year (73.6%), mean age being 66.8 ± 7.06 year. The most commonly presented skin complaints were eczematous dermatitis (42.6%), fungal infection (19.14%), generalized pruritus (5.06%), seborrheic dermatitis (5.06%), urticaria (4.75%) and viral infections (4.29%) respectively. Tinea corporis (29.3%) was the most common of fungal infections and herpes zoster (82.14%) was the most frequent of viral infections. Conclusion: Eczematous dermatitis was found to be the most common noninfectious disease and fungal infection was the most common infectious disease in all age groups and genders. Bangladesh Journal of Medical Science Vol.18(1) 2019 p.130-135

scholarly journals Fungal Infections among Teledermatology Consultations in Dermatology Department of a Tertiary Care Hospital: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (243) ◽  
pp. 1094-1097
Author(s):  
Sagar Mani Jha ◽  
Anil Kumar Singh Dangol ◽  
Bhabendra Suwal ◽  
Jyotshna Yadav
Keyword(s):  
Confidence Interval ◽  
Binary Data ◽  
Tertiary Care Hospital ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Dermatology Department

Introduction: Teledermatology provides virtual consultation to patients using telecommunication technology. Using this method dermatologists can diagnose a condition with the help of pictures of the lesions and short history. During the COVID-19 pandemic, practicing this method has become more relevant. Providing teleconsultations to patients with fungal skin infections can prevent inadvertent use of topical corticosteroids. The objective of this study was to find the prevalence of fungal infections among teledermatology consultations done in a tertiary care hospital. Methods: It was a descriptive cross-sectional study where the store and forward and real-time methods were used between February 2020 to July 2020. Ethical clearance was taken from the institutional review board (reference number: 245). Data of those patients who wanted consultations from this department were sent by medical officers deployed in military hospitals that are under the central army hospital located in Kathmandu. Convenient sampling was used. The collected data was entered and analyzed in the Statistical Package of Social Sciences version 20. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data. Results: A total of 451 (33.45%) (30.93-35.97 at 95% Confidence Interval) were diagnosed with fungal infections out of 1348 patients who were enrolled for the study. About 361 (80%) of the patients suffering from fungal infections belonged to the Terai region and 90 (20%) belonged to mountainous areas. Conclusions: The prevalence of fungal infection among teledermatology consultation was lower than the findings from a similar international study.

scholarly journals Pattern of Dermatologic Disorders in Infants

2013 ◽  
Vol 3 (2) ◽  
pp. 80-84
Author(s):  
Mahfuza Hussain ◽  
BH Nazma Yasmeen ◽  
SM Shaheedul Islam ◽  
Narul Amin ◽  
Jamila Begum
Keyword(s):  
Bacterial Infections ◽  
Skin Diseases ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Care Hospital ◽  
Different Ages ◽  
Common Skin ◽  
Dermatological Disorders ◽  
Male Patients ◽  
One Year

Background: Pattern of skin disorders varies in different ages and in different countries. This pattern also varies among children of different ages. The prevalence pattern reflects socioeconomic, environmental and hygienic condition of a community. Objective: This study was planned to evaluate the magnitude of skin diseases and pattern of various dermatoses among children below one year of age in a major tertiary care hospital in the capital of Bangladesh. Method: A retrospective study was undertaken to determine the pattern of skin diseases during the period of January 2010 to June 2012 at the dermatology outpatient department of a tertiary care pediatric hospital in the capital of Bangladesh. Data were analyzed to determine the pattern of skin diseases in children less than one year of age, seen at the Out Patient Department (OPD) of Dhaka Shishu Hospital (DSH). Results: A total of 36608 cases were seen at the dermatological OPD of DSH out of which 9293 (25.39%) were less than one year of age. The frequency of distribution of dermatological diseases was more in male patients 58.2% than in female patients 41.8%. Neonates were 649 (7%) and rest were infants were 8644 (93%). Eczema was the most common skin disorder (55.41%) followed by impetigo & other bacterial infections (27.55%) and scabies (23.44%). Cutaneous fungal infections were 13.99%, miliaria was 4.9%, erythema neonatorum 4.42%, urticaria was 2.18%, bullous lesions 1.45%, haemangioma 1.17% and pityriasis alba 1.15%. About 16 other dermatological disorders were indentified each of which was less than 1% in distribution. Conclusions: Eczema, superficial bacterial infections, scabies and superficial fungal infections were most common dermatological problem in infants. Birdem Med J 2013; 3(2): 80-84 DOI: http://dx.doi.org/10.3329/birdem.v3i2.17210

scholarly journals Drug prescribing pattern of antifungal drugs for local fungal infections in a tertiary care hospital: MAMC, Agroha

2021 ◽  
Vol 10 (6) ◽  
pp. 689
Author(s):  
Preety Bansal ◽  
Seema Baishnab ◽  
Ashima Singla
Keyword(s):  
Drug Utilization ◽  
Tertiary Care Hospital ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Antifungal Drugs ◽  
Economic Consequences ◽  
Care Hospital ◽  
Drug Prescribing ◽  
Prescribing Practices ◽  
Prescribing Pattern

Background: Drug utilization research or studies are the powerful exploratory tools to ascertain the role of drugs in the society which refers to the marketing, distribution, prescription and use of drugs with special emphasis on the medical, social and economic consequences. Periodic prescription audit in form of drug utilization study is a way to improve the quality of prescription and promote rational prescribing.Methods: This was a prospective and an observational study. Prescriptions included all newly diagnosed patients with cutaneous fungal infection of both sexes who attended dermatology OPD. Factors considered were sociodemographic parameters and WHO prescribing indicators.Results: 1000 prescriptions were analysed of patients between 18 to 65 years of age with cutaneous fungal infections. The average number of drugs per encounter was 3.68. The percentage of drugs prescribed by generic name was 50.33% and the percentage of drugs prescribed from NLEM was 20.93%.Conclusions: This study indicates that prescribing practices of drugs in tertiary care hospital can be improved by promoting generic name drug prescribing, prescribing drugs from NLEM and by reducing polypharmacy.

scholarly journals Clinico-mycological Study of Dermatophytosis and Their Antifungal Susceptibility, A Hospital Based Study

2021 ◽  
Vol 19 (1) ◽  
pp. 30-36
Author(s):  
Manish Bhakta Pradhan ◽  
Vikash Paudel
Keyword(s):  
Fungal Infections ◽  
Antifungal Susceptibility ◽  
Tertiary Care ◽  
Epidemiological Data ◽  
Common Species ◽  
Antifungal Drugs ◽  
Outpatient Department ◽  
Care Hospital ◽  
Disk Diffusion Test ◽  
Female Ratio

Background: Dermatophytosis refers to superficial fungal infections of keratinized tissues caused by keratinophilic dermatophytes. It is the most common of the superficial fungal infections. Nowadays, these fungal infections are at a rise and run a prolonged course despite of treatment due to resistance to conventional antifungal agents. There is a felt need to conduct an epidemiological studies to know the change in the pattern and causes of widespread resistance. Objectives: This study was aimed at identifying clinico-mycological patterns of dermatophytic infections in patients attending the dermatology outpatient department of a tertiary care hospital in Birgunj and the adjoining areas. Methods: The study included cases of clinically diagnosed dermatophytosis from the outpatient department of Dermatology of National Medical College, Birgunj. Clinical and epidemiological data were collected as per proforma and skin scraping, hair plucking, and nail clipping were done and materials were examined microscopically by KOH mount then cultured on Sabouraud dextrose agar and antifungal susceptibility were done by disk diffusion test. Results: here were 349 patients recruited in the study, with a male: female ratio of 1.6:1. The most commonly affected age group was 20–29 years (27.3%). Tinea corporis was the most common type observed (38.1%). Potassium hydroxide positivity was seen in 228 samples (65.3%) and culture positivity was found in 202 samples (57.9%). The most common species identified was Trichophyton rubrum (55%). The most sensitive drug was itraconazole, and more number of resistances was noted with fluconazole. Conclusion: Dermatophytic infection is ecumenical in distribution with increased frequency in tropical and subtropical countries with variable epidemiology. Inadequate and irregular use of antifungal drugs has led to the emergence of resistant strains, which cause poor treatment outcomes. Thus, it is essential to test for antifungal sensitivity to check for resistance to antifungals.

scholarly journals Prospective Observational Study on Prescribing Pattern of Antifungal Drugs in the 400 Out-Patient Department of Dermatology in a Tertiary Care Hospital

2021 ◽  
Vol 14 (1) ◽  
pp. 311-316
Author(s):  
Rashmeen Naaz ◽  
Sharad Chand ◽  
Nandakumar UP ◽  
Vinay BC ◽  
Bharath Raj KC ◽  
...  
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Fungal Disease ◽  
Antifungal Drugs ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Cost Variability ◽  
Serious Disease

Introduction: Fungal infections have been a serious disease over a few decades. Superficial fungal infections not only cause life-threatening illnesses but slowly reduce the Quality of life of patients. Objective: To study the prescribing pattern of antifungal drugs, distribution of fungal disease, and cost variability between different antifungal drugs prescribed. Materials and methods: Prospective observational study was carried out at Justice K.S. Hegde Charitable Hospital from August 2018 to April 2019. Outpatient departments patient satisfying the inclusion criteria were included in the study. Factors like age, gender, diagnosis, and type of prescribed antifungal drugs along with Price variability among different brands of the drug were considered. Antifungal drug prescriptions of patients were analyzed. Results: More than 50% of the patients were from age 21-40 yrs. Males (51.8%) were more than females (48%). The majority of the drugs prescribed were topically (64%). Tine a corpor is was the most prevalent fungal disease. The Azoles group of Antifungal was most prescribed. And the percentage variability between different brands was high. Conclusion: The study concluded the extensive use of antifungal agents. The highly prescribed drug was found to be luliconazole. The study also concluded that the use of generic prescriptions might reduce the cost of illness and enhance the rational use of the drug.

A study on the antifungal susceptibility pattern of dermatophytes isolated in a tertiary care hospital

2017 ◽  
Vol 6 (05) ◽  
pp. 5379
Author(s):  
Vanathi Sabtharishi* ◽  
Radhika Katragadda ◽  
Thyagarajan Ravinder
Keyword(s):  
Tertiary Care Hospital ◽  
Antifungal Susceptibility ◽  
Tertiary Care ◽  
Antifungal Drugs ◽  
Dilution Method ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Superficial Mycosis ◽  
Broth Dilution ◽  
Common Infections

Recent years, due to increased usage of antifungal treatment worldwide, there is an increased chance of rising resistance among antifungal drugs too. Dermatophytic infections causes’ superficial mycosis and it affects skin, hair and nail. These infections are more common and antifungal drugs are used everywhere to treat those common infections. To conduct a study by determining the antifungal susceptibility pattern in dermatophytic isolates from patients attending dermatology OPD in a tertiary care hospital. A total of 217 samples like hair, nail and skin scrapings were obtained and isolation of dermatophytes was done. Antifungal susceptibility testing for dermatophytes was performed by micro broth dilution method. Antifungal drugs tested were Griseofulvin, Fluconazole, Itraconazole and Ketoconazole. Minimum inhibitory concentration for each drug for fungal isolates was tested and results studied. Fluconazole showed a higher MIC values in the range of 1-8µg/ml. Itraconazole showed the lowest MIC values by micro broth dilution method. Since there is limitation of standard guidelines and protocol, meticulous research must be conducted on effect of antifungals and derive at universally implementable guidelines.

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