A study on abuse of topical corticosteroids in patients who attended dermatology venerology leprosy outpatient department

Background: Topical corticosteroids (TCs) are widely used in the patients affected with dermatoses. Abuse of these agents may cause severe adverse effects. Aim of the study was to study the abuse of TCs in patient who attend Dermatology, Venereology, and Leprosy (DVL) outpatient department. Methods: This prospective observational study was conducted in department of DVL at Rajah Muthiah Medical college, Tamil Nadu during the period of six months from November 2018 to April 2019. The patients were enrolled for the study based on inclusion and exclusion criteria.Results: Totally 50 patients with adverse drug reactions (ADRs) by the abuse of TCs were enrolled for the study. It was found that TCs were abused in all ages and equally in both genders. Nearly 72% of the people used TCs for Tinea infection and 20% of the people used TCs for acne vulgaris. Very high potent TCs such as betamethasone and beclomethasone were abused by 55% of the patient. Tinea incognito (TI) was found as common ADRs by the abuse of TCs (74%). Nearly 88% of the people bought TCs from pharmacies without prescription. Sixteen brands were found as easily accessible and affordable for the patients. Medication adherence were increased by 60% after the patient counselling.Conclusion: This study concludes, TI was found as a common ADR in patients who abused TCs such as betamethasone, beclomethasone and clobetasol. High potent TCs should not be allowed to dispense without prescription. Withdrawal of TCs will reduce the risk of ADRs.

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Service Gap In Hospital Industry- A Patient Centric Analysis

Restaurant Business ◽

10.26643/rb.v118i6.7240 ◽

2019 ◽

Vol 118 (6) ◽

pp. 80-89

Author(s):

T. Muthupandian ◽

A. Sabarirajan ◽

B. Arun ◽

P.S. Venkateswaran ◽

S. Manaimaran

Keyword(s):

Tamil Nadu ◽

Service Providers ◽

Hospital Industry ◽

Major Objective ◽

The People ◽

Coimbatore District ◽

Service Gap ◽

Very High ◽

Century Health ◽

Patient Centric

This paper is having a major objective of finding out the service gap in hospital industry – A patient centric analysis in Coimbatore District. In the 21st century, Health conscious is very high among the people in Tamil Nadu. Before fifty years, people have limited level of hospitals and other allied health services. But today, increases of public, private, corporate and municipal hospitals providing quality services. Hence patients are expecting high quality services from the service providers. The study reveals that services provided in the hospitals have a positive and strong effect on the satisfaction of the inpatients. But reliability is the factor the hospital administrations have to consider.

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Topical Isotretinoin in Acne Vulgaris

TAJ Journal of Teachers Association ◽

10.3329/taj.v29i2.39099 ◽

2018 ◽

Vol 29 (2) ◽

pp. 1-5

Author(s):

M Moksedur Rahman ◽

M Abdullah ◽

M Moazzem Hossain ◽

MA Siddique ◽

M Nessa ◽

...

Keyword(s):

Side Effects ◽

Adverse Effects ◽

Prospective Study ◽

Acne Vulgaris ◽

Topical Therapy ◽

Outpatient Department ◽

College Hospital ◽

Once Daily ◽

Medical College ◽

Cutaneous Reactions

This study was carried out to evaluate the efficacy, safety and adverse effects of topical isotretinoin 0.05% gel in the treatment of acne vulgaris. This prospective study was undertaken in Skin & VD outpatient department of Rajshahi Medical College Hospital, Rajshahi. One hundred patients with mild tomoderate acne vulgaris were enrolled and were instructed to apply isotretinoin 0.05% gel once daily at night for 12 weeks. Patients were followed up at 2,4,8 and 12 weeks for efficacy and tolerability. Efficacy was measured by counting facial inflammatory and noninflammatory lesions and by grading acne severity. Cutaneous tolerance was assessed by determining erythema, scaling and burning with pruritus.Response was excellent in 80%of cases.None of the cutaneous reactions was severe, all were mild and well tolerated.Nobody had to discontinue the therapy for side effects. This study confirms that isotretinoin 0.05% gel is safe and effective topical therapy for mild to moderate acnevulgaris.TAJ 2016; 29(2): 1-5

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Prevalence and pattern of PCOS in women presenting with acne, a hospital based prospective observational study

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20180611 ◽

2018 ◽

Vol 6 (3) ◽

pp. 899

Author(s):

Raja Shareef A. ◽

P. V. S. Prasad ◽

P. K. Kaviarasan

Keyword(s):

Observational Study ◽

Prospective Observational Study ◽

Polycystic Ovarian Syndrome ◽

Acne Vulgaris ◽

Strong Association ◽

Tertiary Care ◽

Final Analysis ◽

Endocrine Disorders ◽

Medical College ◽

Ovarian Syndrome

Background: Acne is one of the most common dermatological conditions encountered in day to day practice. Many recent studies have reported a strong association between acne and underlying systemic endocrine disorders, more particularly Poly cystic ovarian syndrome. But there is scarcity of literature on the subjects in Indian population. Hence the present study was conducted with an objective of studying the association between acne and polycystic ovarian syndrome, in women presenting with adult onset acne to a tertiary care teaching hospital.Methods: A prospective observational study was carried out in department of dermatology, Dhananalakshmi Srinivasan medical college and hospital, Permabalur from January 2016 to August 2017. The study population included women above 18 years of age clinically diagnosed with acne vulgaris. The presence of polycystic ovarian syndrome was assessed using Rotterdam criteria.Results: The final analysis had included 100 women with acne. The most common type of lesion observed was comedone in 91% of women. The other most common lesions were papule seen in 73%, pustule in 35% of women. The proportion with grade I, Grade II and grade III acne was 58%, 29% and 13% respectively. The prevalence of PCOS was 30% (95% CI 21.89% to 39.58%). PCOS had shown no statistically significant association with age, marital status and regularity of menstrual cycle. The factors which have shown statistically significant association were higher BMI, presence of Hirsutism and higher waist circumference.Conclusions: PCOS is highly prevalent among women with acne. Presence of hirsutism, obesity are strong risk factors for PCOS.

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Self-medication practices versus health of the community

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20173169 ◽

2017 ◽

Vol 4 (8) ◽

pp. 2757

Author(s):

Ruma Dutta ◽

Dinesh Raja ◽

Anuradha R. ◽

Lawrence Dcruze ◽

Timsi Jain ◽

...

Keyword(s):

Tamil Nadu ◽

Data Entry ◽

Sampling Technique ◽

Simple Random Sampling ◽

Community Medicine ◽

Self Medication ◽

Cross Sectional ◽

Medical College ◽

The People ◽

Field Practice

Background: Self-medication is a common practice worldwide and the irrational use of drugs is a cause of concern. Self-medication involves the use of medicinal products by the individuals to treat self-recognized disorders or symptoms, or the intermittent or continuous use of a medication prescribed by a physician for chronic or recurring diseases or symptoms. The objectives of the study were to find out the prevalence of self-medication practices in the community; to describe the common conditions where self-medication is practiced.Methods: A community based cross sectional study was conducted in a rural population at Kuthambakkam village, Tamil Nadu from February 2015 to July 2015. This village falls under the rural field practice area of Department of Community Medicine, Saveetha Medical College and hospital, Thandalam. There were 1175 households in this village of which 165 households were identified for the study purpose using simple random sampling technique. Statistical analysis: Data entry and analysis was done using SPSS version 16 software. Descriptive statistics were calculated for background variables, attitude and practices of self-medication. Results: The study was conducted in 165 households in Kuthambakkam village, the rural field practice area of Department of Community Medicine, Saveetha Medical College. The median age of the study participants was 38 years. The minimum age was 17 and maximum was 77 years. 73 (44.2%) of study subjects reported having health problems currently. Of them, 76.7% replied they consulted a doctor for their problem, 17.8% resorted to self-medication and rest 5.5% took native treatment at home. Conclusions: It is imperative to address the practice of self-medication among the people in the age of growing drug resistance being reported. Periodic studies on the knowledge, attitude and practice of self-medication may give an insight into the pattern of drug use among the people.

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Prescription pattern of drugs in ENT outpatient department of tertiary care teaching hospital

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20183430 ◽

2018 ◽

Vol 7 (9) ◽

pp. 1688

Author(s):

Usha Joshi ◽

Hansa Banjara ◽

Rajesh Hishikar ◽

Ravindra Chandrakar

Keyword(s):

Prospective Observational Study ◽

Tertiary Care ◽

Age Groups ◽

Oral Route ◽

Outpatient Department ◽

Prescription Pattern ◽

Care Teaching ◽

Medical College ◽

Antiulcer Drugs ◽

Nose And Throat

Background: Diseases of the ear, nose and throat (ENT) are common among general population affecting all age groups and accounts for most of the drugs prescribed and used. The aim of the study is to assess the prescription pattern of drugs in ENT outpatient department in a tertiary care teaching hospital.Methods: A prospective observational study was conducted from December 2017 to May 2018 in the ENT OPD (Outpatient department) at Pt. J.N.M. Medical College and associated Dr. B.R. Ambedkar Memorial Hospital, Raipur. Data were collected in a proforma and evaluated.Results: A total of 313 prescriptions were analysed. Most of the patients (40.89%) belonged to 13 - 35 years age group.185 patients (59.10%) were male and 128 patients were females (40.90%). A total of 1003 drugs were prescribed. The average number of drugs per prescription was 3.2. Most common class of drugs prescribed was antimicrobials (24.42%), followed by H1 antihistaminics (18.84%), antiulcer drugs (15.55%) and nonsteroidal anti-inflammatory (NSAIDs) drugs (14.35%). The average number of antimicrobials per prescription was 0.78. One or two antimicrobials were prescribed in 202 prescriptions (64.53%). The most common prescribed antimicrobial was of Penicillin group (64.89%) followed by Fluoroquinolone (25.71%). The most common prescribed route of drug administration was oral route (81.35%). The most common prescribed dosage form was tablets (74.87%). FDC constituted 24.62% of prescribed drugs.Conclusions: The study revealed that the most common class of drug prescribed was antimicrobials followed by H1 antihistaminics, antiulcer drugs and NSAIDS.

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Medication errors and adverse drug reactions in psychiatry department: A prospective observational study

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl4.4538 ◽

2020 ◽

Vol 11 (SPL4) ◽

pp. 2669-2674

Author(s):

Dona Thomas ◽

Sharon Thomas ◽

Venkateswaramurthy N ◽

Sambathkumar R

Keyword(s):

Observational Study ◽

Medication Errors ◽

Adverse Drug Reactions ◽

Tamil Nadu ◽

Prospective Observational Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Drug Reactions ◽

Psychiatry Department

The study was aimed to analyse the pattern of medication errors and drug interaction induced adverse drug reactions in the psychiatry department of a tertiary care hospital. A Prospective observational study being conducted in the inpatient and outpatient department of psychiatry in a tertiary care hospital, Erode, Tamil Nadu for over six months. A total of 80 prescriptions with psychiatric illness and 174 medication errors were observed. Of the 174 medication errors observed, 132(75.8%) were incomplete prescriptions making the highest number of medication errors. The highest number of errors occurred due to Prescription error 156(89.0%), followed by administration error 8(4.5%). According to the NCCMERP classification, the majority of medication errors were coming under category B 120(68.9%) but there is no harm. The demographic reports of outpatients in the present study showed a higher incidence of medication errors in patients with the age group of 31-40 years 25(36.7%). Considering the factors contributing to a medication error, refusal of the patient to take the drug 27(39.7%) followed by forgetting 13(19.1%) due to the vulnerable characteristics of the patient was more significant. Although there is a general lack of awareness, many patients and bystanders are unaware of their diagnosis and medications. It is, therefore, a crucial step to educate and make them aware of the correct use of medicine.

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Prospective observational study of cutaneous adverse drug reactions at a tertiary medical college

Medpusle International Journal of Medicine ◽

10.26611/10219213 ◽

2019 ◽

Vol 9 (2) ◽

pp. 138-142

Author(s):

Preetham Pottipati ◽

◽

N Sai Pujitha ◽

Madhavilatha Midde ◽

Praveena Thiriveedhi ◽

...

Keyword(s):

Observational Study ◽

Adverse Drug Reactions ◽

Prospective Observational Study ◽

Drug Reactions ◽

Medical College

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Efficacy of Topical Tretinoin, Benzoyl Peroxide and Oral Tetracycline Combination in Acne Vulgaris

TAJ Journal of Teachers Association ◽

10.3329/taj.v19i1.3161 ◽

2009 ◽

Vol 19 (1) ◽

pp. 10-12

Author(s):

MM Hossain ◽

MA Al-Amin

Keyword(s):

Complete Remission ◽

Benzoyl Peroxide ◽

Marked Improvement ◽

Acne Vulgaris ◽

Medical College Hospital ◽

Outpatient Department ◽

Topical Tretinoin ◽

College Hospital ◽

Medical College

This study was done in the outpatient department of Rajshahi Medical College Hospital from January 2004 to December 2005. In this study the efficacy of topical tretinoin, benzoyl peroxide and oral tetracycline was studied in 50 patients. Forty five patients completed the course of treatment and 5 patients were defaulter. Complete remission was seen in 32 (71.11%), marked improvement in 08 (17.78%) and good response in 05 (11.11%) patients. Application of topical tretinoin cream (0.05%) in the evening, benzoyl peroxide cream (5%) in the morning and oral tetracycline (500 mg bd) before meal was found very effective, safe and cheap in the treatment of comedonal, pustular and pustulo-nodular acne vulgaris. doi: 10.3329/taj.v19i1.3161 TAJ 2006; 19(1): 10-12

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Pattern of adverse drug reactions occurring at department of neurology of a tertiary care hospital in India

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20201756 ◽

2020 ◽

Vol 9 (5) ◽

pp. 772

Author(s):

Virendra Kushwaha ◽

Pooja Agrawal ◽

Ruchi Srivastava ◽

Alok Verma

Keyword(s):

Adverse Drug Reactions ◽

Joint Pain ◽

Prospective Observational Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Relevant Information ◽

Care Hospital ◽

Drug Reactions ◽

Medical College ◽

Antiparkinsonian Drugs

Background: The objective of the study was to study the pattern and trends of adverse effects of drugs used in department of neurology in a tertiary care hospital.Methods: A prospective, observational study was carried out for a duration of 12 months from November 2018 to October 2019 at Department of Neurology and Department of Pharmacology and Therapeutics, G.S.V.M. Medical College, Kanpur after getting an approval from institutional ethical committee. Data was collected by analyzing OPD prescription slip, treatment charts and investigation reports. All relevant information regarding adverse drug reactions (ADRs) were collected as per norms of Indian Pharmacopoeia commission (IPC).Results: During the study period, a total of 130 ADRs reported. Most of the ADRs were reported due to antiepileptic drugs followed by antiparkinsonian drugs. Dizziness was the most frequent ADR reported. Most of the ADRs were reported due to phenytoin. Other ADRs observed were drowsiness, nausea/vomiting, weakness, joint pain, dyskinesia.Conclusions: Most of the ADRs were due to anti-epileptic drugs. Most of the reactions were of mild severity.

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Clinico-pathological study of cases of histoid leprosy

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20202650 ◽

2020 ◽

Vol 6 (4) ◽

pp. 474

Author(s):

Kaveri M. ◽

Vishal V. Wali

Keyword(s):

Prospective Observational Study ◽

Rare Variants ◽

Normal Skin ◽

Pathological Study ◽

Diagnostic Challenge ◽

Histopathological Features ◽

Medical College ◽

Potential Reservoir ◽

Very High ◽

Bacterial Index

Background: Rare variants of leprosy pose a diagnostic challenge and histoid leprosy is one such form of disease with unique clinical and histopathological features. The objective of the study was to study clinical and histopathological features of histoid leprosy.Methods: A prospective observational study was conducted at M. R. Medical College and Basveshwar teaching and general hospital, Kalaburagi from July 2018 to October 2019. Newly diagnosed and histologically proven cases were included.Results: Histologically confirmed histoid leprosy accounted for 8 cases (7 males and 1 female). Mean age of the patients was 44.5 years. Patients presented with papules, plaques and nodules over an apparently normal skin. Bacterial index ranged from 4+ to 6+ according to Ridley index. Histopathology showed circumscribed lesion with free sub-epidermal grenz zone and spindle shaped cells.Conclusions: As bacillary load is very high in these patients, they can form a potential reservoir of infection in the community especially in post leprosy elimination era.

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