scholarly journals Frey’s procedure: short term follow up results in terms of pain, endocrine and exocrine status, a tertiary care centre experience

Author(s):  
C. Sugumar ◽  
S. Balakumaran ◽  
Mukund Mundra

Background: Chronic pancreatitis, a debilitating disease which affects the patient to an extent to render him bedridden sometimes and often make him/her unable to perform daily work, leading to poor quality of life, severe emotional stress and financial burden. Frey’s procedure one of the most commonly performed surgery in patient of chronic pancreatitis with stones in pancreatic duct and small inflammatory head mass. This procedure had shown promising results in terms of pain control with unclear outcome with respect to exocrine and endocrine status.Methods: Study was conducted in Government Kilpauk Medical College, Chennai during March 2016 to December 2019. Total 21 patients were followed up for 18 months and Post-operative pain was analysed using pain scoring system used by Bloechle et al. Exocrine status in terms of diarrhea, bloating sensation and Fecal Elastase level(preoperative and postoperative) were analysed. Patient glycaemic status were also analysed and compared. Patient Nutritional status was analysed in terms of weight gain.Results: In this study there was significant improvement in pain after surgery in terms of VAS pain Score (Preop Mean-82.14, Post-op Mean- 9.76, p<0.001) , frequency of pain (Preop Mean-78.57, Post-op Mean- 14.29, p<0.001), analgesia required (Preop Mean-15, Post-op Mean- 3.10, p<0.001), and inability to work due to pain (Preop Mean-80.95, Post-op Mean- 11.90, p<0.001). Overall total Pain score was significantly improved after surgery (Preop Mean-256.67, Post-op Mean- 39.05, p<0.001). There was significant weight gain and significant improvement in Fecal Elastase level in patients following surgery, however there was no significant difference in pancreatic exocrine status on the basis of symptoms.Conclusions: Frey’s procedure is very effective in pain control in properly selected patients of chronic calcific pancreatitis, and it also improves nutritional status of patient. Frey’s procedure might improve patient exocrine and endocrine status but further  multicentre studies are needed to come to a conclusion. 

2011 ◽  
Vol 1 (2) ◽  
pp. 42
Author(s):  
Niloufar Jenabian ◽  
Ezzatollah Naderi ◽  
Ali-Akbar Moghadamnia ◽  
Samir Zahedpasha

Aim: Scaling and root planing (SRP) is a major component of periodontal therapy which is often accompanied by painful experiences for the patient.  The objective of the present study is to evaluate the pain control of two available types of ibuprofen, soft gelatin capsules and tablets, following SRP in patients with chronic periodontitis. Methodology: 75 patients with chronic periodontitis, undergoing routine periodontal SRP were selected. Following probing the amount of pain perceived was recorded as the baseline pain using visual analog scale (VAS). Further, they received either 800 mg ibuprofen tablet, 800 mg ibuprofen capsule or placebo and the pain level was measured thirty minutes thereafter. Participants underwent SRP procedure and the pain levels were recorded immediately and then at 30 and 60 minutes after SRP. Results: The mean VAS pain scores assessed immediately, thirty minutes and an hour after SRP for both ibuprofen and ibuprofen capsule groups were lower than placebo. Significant difference in the pain parameter only immediately after SRP between three groups were observed (p=0.012).The mean VAS pain score difference after thirty minutes and an hour upon SRP with baseline was insignificant in all study groups (p≤0.0001). However, the mean VAS pain score measured an hour after SRP showed significant difference between both NSAID groups and placebo group (p=0.012) Conclusions: Soft gelatin ibuprofen capsules are well suitable for pain management during SRP procedure in patients with chronic periodontitis due to reported rapid onset of action and less gastrointestinal intolerance.  How to cite this article: Jenabian N, Naderi E, Moghadamnia AA, Zahedpasha S. Comparison between Soft Gelatin Capsule Containing Ibuprofen and Ibuprofen Regular Tablet in Pain Control Following Scaling and Root Planing. Int Dent Res 2011;2:42-47. Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Nik Amin Sahid ◽  
Firdaus Hayati ◽  
Challa Venkata Rao ◽  
Rosnelifaizur Ramely ◽  
Ikhwan Sani ◽  
...  

Background. Snakehead fish (Channa striatus) is a fresh water fish indigenous to many Asia countries and believed to have medical value. Studies showed that it contains all the essential amino acids and fatty acids able to accelerate wound healing and it has antinociceptive effect. However, little human study has been done to assess the effectiveness of Channa striatus in wound healing. A prospective RCT has been conducted on the effect of Channa striatus spray versus placebo on clean wound to assess its pain control effect and cosmetic outcome. Methodology. One hundred and two patients (102) underwent clean elective surgery; postoperatively they were randomized into two group. One group received Channa striatus extract spray (n=51) another group received placebo (n=51) on daily basis for 2 weeks. They were followed up on 2nd, 4th, and 6th weeks. Pain control effect was assessed based on Visual Analog Pain Score (VAPS) and cosmetic outcome based on Visual Analog Cosmetic Scale (VACS), Wound Evaluation Scale (WES), and Vancouver Scar Scale (VSS). Result. The patient treated with Channa striatus spray displayed a better outcome in terms of pain control compared to placebo. During analysis using repeated measure ANOVA, there was significant difference of patient’s pain score based on VAPS between Channa striatus spray and placebo (F-stat (df) = 4.80 (2), p-value = 0.010). For cosmetic outcome it showed a better result in Channa striatus spray group for all the 3-scoring system, VACS, (F-stat (df) = 2.68 (2) , p-value <0.001), WES (F-stat (df) = 3.09 (2), p-value = 0.048), and VSS (F-stat (df) = 1.72 (2) , p-value = 0.011). Conclusion. Our study suggest that application of Channa striatus extract spray on clean wound has shown a significant better pain score result and cosmetic outcome on week 2, week 4, and week 6 comparatively with placebo.


2018 ◽  
Vol 5 (2) ◽  
pp. 462 ◽  
Author(s):  
Chaitra K. M. ◽  
Bhavya G. ◽  
Harish S. ◽  
Shruthi Patel ◽  
Syeda Kausar Anjum

Background: Critically-ill children have a state of metabolic stress. The nutritional needs of these patients can be increased. Their nutritional status at admission and its possible deterioration during hospitalization can be a predictor of worse outcome. The objective of this study was to study the influence of nutritional status on outcomes like mortality, duration of mechanical ventilation and duration PICU stay and hospital stay, in critically ill children.Methods: This was a prospective comparative study conducted on 60 critically ill children aged 1 month to 18 years admitted to PICU of tertiary care, teaching hospital, Bangalore, Karnataka over a study period of 12 months. Patients were divided into 4 categories based on Body mass index (BMI) as per WHO growth charts into: underweight, normal, overweight and obese and outcomes was analysed.Results: In the present study 60 children were studied. Subjects were classified as underweight (23.33%), normal weight (45%), overweight/obese (31.67%) based on BMI Z-score at admission. The odds of prolonged hospital stay were higher in underweight and overweight/obese children (OR-2.85, p-0.12 and OR-3.92, p-0.03 respectively). Underweight and overweight/ obese children had higher odds for prolonged PICU stay. (OR-6, p-0.02 and OR-2.13, p-0.36 respectively). Underweight children required prolonged ventilator support (OR-2, p-0.03). There was no significant difference among the group.Conclusions: There is a high prevalence of malnourishment in critically ill children compared to general population and they are prone for poor outcome. Malnourished children must be identified at admission and optimal therapies, nutritional strategies aimed at preventing further nutritional deterioration should be made.


2021 ◽  
Vol 7 (2) ◽  
pp. 442-447
Author(s):  
Divya Motwani ◽  
Rupali Maheshgauri ◽  
Prachi Bakare ◽  
Deepaswi Bhavsar ◽  
Sucheta Kaul ◽  
...  

A potential complication of cataract surgery is posterior capsular rent, where PCIOL can’t be implanted. Primary Iris claw implantation means that the IC-IOL is implanted in the same setting after cataract removal. While secondary Iris claw lens implant is done in an aphakic eye without capsular support and post cataract surgeries when the eye is left aphakic. To compare the visual outcome in cases of primary and secondary iris claw lens implantation after cataract surgery.This was a hospital-based Prospective Interventional Longitudinal study,conducted on patients in a tertiary care centre, in Western Maharashtra from September 2018 to August 2020. 31 eyes underwent primary iris claw implant and 19 underwent secondary iris claw implant. Highly significant difference in visual acuity preoperatively due aphakia among subjects who underwent secondary iris claw implantation (p=0.000) was seen. Highly significant difference in visual acuity post operatively till 15 days was also seen due to less corneal oedema& inflammation in patients who underwent secondary iris claw implantation. No significant difference in visual acuity was seen on day 40 as lens was put in both the groups and the signs of inflammation had reduced (p=0.759).Overall visual outcome after 40 days is comparable in primary and secondary cases. It is better to do a primary retro fixated iris claw implantation, as in case of a secondary implant the patient will have undue anxiety, to undergo a second surgery along with increased financial burden and patient can develop complications due to aphakia.


2000 ◽  
Vol 118 (4) ◽  
pp. A1071
Author(s):  
Laura E. Matarese ◽  
Darwin L. Conwell ◽  
Douglas L. Seidner ◽  
Gregory Zuccaro ◽  
Ezra Steiger

2021 ◽  
Vol 11 (2) ◽  
pp. 182-186
Author(s):  
Satya Prasad Samantaray ◽  
Tanmay Dutta

Identification of factors predicting the outcome of surgery for chronic pancreatitis and preparation of a scoring system to predict the outcome following surgery. A total number of 76 patients who had undergone surgery for chronic pancreatitis were prospectively followed at Department of General Surgery, S.C.B. Medical College, Cuttack during the period from 2010-2013. Data on demographic details, pain score, opioid addiction, exocrine and endocrine insufficiency, insulin requirement and morphology of pancreas on imaging were recorded. On follow up, improvement in pain score and exocrine and endocrine insufficiency were recorded. Factors affecting surgical outcome were determined and a scoring system was done. The mean age of patients was 39.7±7.9 years (range 18-58 years). Chronic alcohol intake was the predominant cause accounting for 56% (n=34) cases. Mean pain score at admission on Visual Analogue Scale (VAS) was 5.98. Twenty-six patients (43.3%) were found to have endocrine insufficiency and 22 (36.6%) patients had exocrine insufficiency. Forty-two patients underwent Partington-Rochelle procedure, and 18 patients underwent Frey’s procedure. Eighty percent of patients (n=48) had significant pain relief. On logistic regression, preoperative VAS score, number of previous admissions, opioid dependence, main pancreatic duct (MPD) diameter, number and site of calcifications were found to be significant in predicting pain relief. Cohort of patients with chronic pancreatitis likely to get benefit from surgery can be predicted preoperatively.


2017 ◽  
Vol 8 (3) ◽  
pp. 151-154 ◽  
Author(s):  
Elaine Brooks ◽  
Susan H. Freter ◽  
Susan K. Bowles ◽  
David Amirault

Background: Pain management after elective arthroplasty in older adults is complicated due to the risk of undertreatment of postoperative pain and potential adverse effects from analgesics, notably opioids. Using combinations of analgesics has been proposed as potentially beneficial to achieve pain control with lower opioid doses. Objective: We compared a multimodal pain protocol with a traditional one, in older elective arthroplasty patients, measuring self-rated pain, incidence of postoperative delirium, quantity and cost of opioid analgesics consumed. Methods: One hundred fifty-eight patients, 70 years and older, admitted to tertiary care for elective arthroplasty were prospectively assessed postoperative days 1–3. Patients received either traditional postoperative analgesia (acetaminophen plus opioids) or a multimodal pain protocol (acetaminophen, opioids, gabapentin, celecoxib), depending on surgeon preference. Self-rated pain, postoperative delirium, and time to achieve standby-assist ambulation were compared, as were total opioid doses and analgesic costs. Results: Despite receiving significantly more opioid analgesics (traditional: 166.4 mg morphine-equivalents; multimodal: 442 mg morphine equivalents; t = 10.64, P < .0001), there was no difference in self-rated pain, delirium, or mobility on postoperative days 1–3. Costs were significantly higher in the multimodal group ( t = 9.15, P < .0001). Knee arthroplasty was associated with higher pain scores than hip arthroplasty, with no significant difference in opioid usage. Conclusion: A multimodal approach to pain control demonstrated no benefit over traditional postoperative analgesia in elective arthroplasty patients, but with significantly higher amounts of opioid consumed. This poses a potential risk regarding tolerability in frail older adults and results in increased drug costs.


Surgery Today ◽  
2017 ◽  
Vol 48 (1) ◽  
pp. 80-86 ◽  
Author(s):  
Hideaki Sato ◽  
Masaharu Ishida ◽  
Fuyuhiko Motoi ◽  
Naoaki Sakata ◽  
Takeshi Aoki ◽  
...  

2019 ◽  
Vol 26 (04) ◽  
Author(s):  
Muhammad Usman ◽  
Kaiser Saleem ◽  
Saddaqat Hayat

Objectives: Compare the efficacy in terms of mean pain score and mean duration of hospital stay in patients of symptomatic cholilithiasis undergoing laproscopic cholecystectomy with and without subhepatic drain insertion. Study Design: Randomized control trial. Setting: Surgical unit –iii of Allied Hospital Faisalabad which is tertiary care unit. Duration of Study: 20-02-2013 to 20-08-2013. Results: Out of 150 cases (75 cases in two groups), mean+sd was calculated as 44.74+ 6.57 years, 80%(n=60) in Group-A and 82.66%(n=62) in Group-B were female, post- operative hospital stay was recorded which shows 3.16+0.463 in group-a and 2.32+0.569 days in group-b and it shows statistically significant difference between the two groups, similarly, on comparison of post-operative abdominal pain score at 24 hours in both groups 2.266+1.062 in Group-A and 1.8+0.90 in Group-B pain on vas was recorded at 24 hours which shows significantly lower in Group-B patients by calculating p value as 0.002348. Conclusion: No subhepatic drain insertion after laproscopic cholecystectomy is better when compared to those with subhepatic drain insertion in terms of mean pain score and mean duration of hospital stay in days post operatively.


2018 ◽  
Vol 5 (2) ◽  
pp. 595
Author(s):  
Arvind Chavan ◽  
Shraddha Dubewar ◽  
Sarfaraz Ahmed ◽  
Saleem H. Tambe

Background: Communicable diseases like acute respiratory infections and diarrhea are the major killer of less than five populations. This is especially true among those who are malnourished. Malnutrition is related to the increased morbidity and mortality due to diarrhea. The objective of this study was to study nutritional status of infant and young children at a tertiary care hospital and factors affecting the nutritional statusMethods: A hospital based cross sectional study was carried out. A total of 165 children were included in the study which comprised of 107 males and 58 females. The study was carried out for a period of one year. Anthropometric measurements and their interpretation were done as per WHO guidelines.Results: Out of 165, 19 children were under weight and 3 were overweight. 143 children were well nourished according to the WHO standards. 18 were having wasting and two were obese. There was no significant difference in nutritional status of children in relation to education of their mothers; with respect to weight for age (p = 0.265) and height for age (p = 0.425). There was no difference in nutritional profile of bottle fed and non-bottle-fed children. Conclusions: Majority of children (143/165) were well nourished. There was no difference in the nutritional profile of children among those of graduate and non-graduate mothers. There was no difference in nutritional profile of bottle fed and non-bottle-fed children.


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