Epidemiologic study of chronic osteomyelitis in Paktya and Kabul, Afghanistan

Background: Osteomyelitis is an infection of the bone that can occur from direct or indirect invasion by a pathogens, both of these types can potentially progress to subacute and chronic osteomyelitis that lasts longer than 4 weeks. This disease has important characteristics such as long-term clinical course, long periods of silence, the treatment of the recurrence of serious complications of the disease is difficult financially and it takes a lot of money epidemiology of chronic osteomyelitis in the Afghanistan is largely unknown. The aim of this study was epidemiologic study of chronic osteomyelitis in adult clients of Paktya city regional hospital and Wazir Akbar Khan Hospital in Kabul city of Afghanistan.Methods: This descriptive cross-sectional study was performed in patients' with chronic osteomyelitis who referred in this two hospitals in Paktya city regional hospital and the Wazir Akbar Khan hospital in Kabul During the March 2019 to March 2020, 70 patients were identified with chronic osteomyelitis. The information required for the study, such as general information, underlying diseases of the patients collected from these two medical centers. After encoding, the necessary information was entered into the computer and analyzed.Results: According to the findings of this study the prevalence of chronic bone infections in male were 64% (n=45) in female were 36% (n=25), current findings showed 44.3% of all patient involved with tibial (n=31) chronic osteomyelitis and the most common underlying disease causing chronic osteomyelitis is the direct entry of infection as a result of trauma.Conclusions: Our study showed the chronic osteomyelitis is higher in the male population than in the female population and highest incidence of chronic osteomyelitis site was tibia result of trauma because of humid climate, poor personal and hospital environmental health status and relatively poor medical facilities in Afghanistan may contribute to higher morbidity.

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Prevalence of metabolic syndrome in type 2 diabetic patients

International Journal of Scientific Reports ◽

10.18203/issn.2454-2156.intjscirep20212834 ◽

2021 ◽

Vol 7 (8) ◽

pp. 416

Author(s):

Tina Uprety ◽

Saroj Kunwar ◽

Ashim Rai ◽

Avaya Khanal ◽

Shraddha Thapa ◽

...

Keyword(s):

Risk Factors ◽

Metabolic Syndrome ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Male Population ◽

Type 2 Diabetic Patients ◽

Cross Sectional ◽

Female Population ◽

Type 2 Diabetic

Background: Metabolic syndrome (MetS) and diabetes mellitus concurrently potentiates a number of risk factors, significantly higher prevalence of cardiovascular diseases. Numerous risk factors associated with diabetes gets intensified by the presence of metabolic syndrome. Diabetes and metabolic syndrome together can increase the risk of cardiovascular disease by 2 to 4 folds. The main objective of this study was to determine the prevalence of MetS in type 2 diabetic mellitus (T2DM) patients. Components of metabolic syndrome were measured and compared to determine the prevalence.Methods: Hospital based cross-sectional study was conducted from September 2019 to December 2019 at star hospital and modern technical college, Sanepa, Nepal. A total number of 353 patients with T2DM visiting star hospital were included in the study.Results: Among 353 participants, MetS was diagnosed in 242 (68.5%) participants using NCEP-ATP III criteria. The prevalence of MetS was 68.5% among which male were 123 (76.3%) and female were 119 (61.9%). MetS was found to be highest in age group of 50-59 years with 34.2% (83) participants. Dyslipidemia with raised TG (triglyceride) 71.4% and reduced HDL 76% was found to be most prevalent component in our study followed by hypertension 73.1%.Conclusions: 68.5% prevalence of MetS in T2DM with 76.3% male and 61.9% female according to NCEP-ATP III was found with anthropometric indices significantly higher in the male population compared to female population.

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Prevalence and distribution of peripheral musculoskeletal manifestations in spondyloarthritis including psoriatic arthritis: results of the worldwide, cross-sectional ASAS-PerSpA study

RMD Open ◽

10.1136/rmdopen-2020-001450 ◽

2021 ◽

Vol 7 (1) ◽

pp. e001450

Author(s):

Clementina López-Medina ◽

Anna Molto ◽

Joachim Sieper ◽

Tuncay Duruöz ◽

Uta Kiltz ◽

...

Keyword(s):

Psoriatic Arthritis ◽

Latin American ◽

Underlying Disease ◽

Cross Sectional Study ◽

Joint Disease ◽

Joint Involvement ◽

Cross Sectional ◽

Small Joint ◽

Musculoskeletal Manifestations ◽

Inflammatory Bowel

ObjectivesTo characterise peripheral musculoskeletal involvement in patients with spondyloarthritis (SpA) including psoriatic arthritis (PsA), across the world.MethodsCross-sectional study with 24 participating countries. Patients with a diagnosis of axial SpA (axSpA), peripheral SpA (pSpA) or PsA according to their rheumatologist were included. The investigators were asked which diagnosis out of a list of six (axSpA, PsA, pSpA, inflammatory bowel disease-associated SpA, reactive arthritis or juvenile SpA (Juv-SpA)) fitted the patient best. Peripheral manifestations (ie, peripheral joint disease, enthesitis, dactylitis and root joint disease), their localisation and treatments were evaluated.ResultsA total of 4465 patients were included (61% men, mean age 44.5 years) from four geographic areas: Latin America (n=538), Europe plus North America (n=1677), Asia (n=975) and the Middle East plus North Africa (n=1275). Of those, 78% had ever suffered from at least one peripheral musculoskeletal manifestation; 57% had peripheral joint disease, 44% had enthesitis and 15% had dactylitis. Latin American had far more often peripheral joint disease (80%) than patients from other areas. Patients with PsA had predominantly upper limb and small joint involvement (52%).Hip and shoulder involvement was found in 34% of patients. The prevalence of enthesitis ranged between 41% in patients with axSpA and 65% in patients with Juv-SpA. Dactylitis was most frequent among patients with PsA (37%).ConclusionThese results suggest that all peripheral features can be found in all subtypes of SpA, and that differences are quantitative rather than qualitative. In a high proportion of patients, axial and peripheral manifestations coincided. These findings reconfirm SpA clinical subtypes are descendants of the same underlying disease, called SpA.

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Prevalence and distribution of causes of infertility according to women’s age – a cross-sectional study in a tertiary healthcare hospital setup

Journal of Basic and Clinical Physiology and Pharmacology ◽

10.1515/jbcpp-2020-0349 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Keerthana Dhandapani ◽

Bhagyalakshmi Kodavanji ◽

Vinodini Nithyananda Madom Anantharaya ◽

Nayanatara Arun Kumar

Keyword(s):

Tertiary Care ◽

Developed Countries ◽

Cross Sectional Study ◽

Female Infertility ◽

Secondary Infertility ◽

Cross Sectional ◽

Female Population ◽

Infertile Women ◽

Tertiary Healthcare ◽

The Individual

Abstract Objectives Infertility has disastrous consequences, particularly for women. Causes of infertility in developed countries have been investigated but there is a significant lack of data among Indian female population. The aim of the present study was to analyze the causes and the proportion of the individual factors contributing to infertility, considering the age factor. Methods The data of 204 infertile women (18–45 years) were collected from the files in tertiary care hospitals. Causes and age of infertile women were grouped. The prevalence of each cause was evaluated. Data analysis was done using SPSS (Statistical Package for Social Sciences) version 17.0. Results Polycystic ovarian syndrome (PCOS) was the most common (14.71%) cause of female infertility. Ovulatory dysfunctions (25.55%) were the foremost cause in primary infertility, whereas in secondary infertility, uterine factors (26.86%) were most common. The incidence of primary and secondary infertility was more evident in patients who were more than 30 years of age. Conclusions Causes of infertility vary according to the age. The causes of female infertility were unexplained infertility, ovulatory disorders and uterine factors most commonly affecting women at ≤30 years.

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A Survey on How Ocular Surface Demodex Infestation Interactively Associates with Diabetes Mellitus and Dry Eye Disease

Acta Parasitologica ◽

10.1007/s11686-021-00382-8 ◽

2021 ◽

Author(s):

Chang Huang ◽

Shuze Chen ◽

Sheng Fu ◽

Yingli Li ◽

Zhenhao Li ◽

...

Keyword(s):

Diabetes Mellitus ◽

Dry Eye ◽

Ocular Surface ◽

Cross Sectional Study ◽

General Information ◽

Potential Interaction ◽

Dry Eye Disease ◽

Eye Disease ◽

Cross Sectional ◽

Demodex Infestation

Abstract Purpose Prevention of ocular surface (OS) Demodex infestation plays an important role in OS hygiene and variety of factors may be associated with it, in which diabetes mellitus (DM) or dry eye disease (DED) has caught the attention of most scholars. However, there has been no research on whether there was a potential interaction between DM and DED in the process of OS Demodex infestation. This cross-sectional study was implemented in Zhujiang Hospital of Southern Medical University. Methods Ophthalmologic interviews, questionnaires, and examinations were conducted. Factors including general information, DM status, dry eye condition, etc. were collected to study the correlation of DM and DED on OS Demodex infestation. Results After statistical analysis, we found that both DM (P < 0.001) and DED (P = 0.013 < 0.05) are closely associated with OS Demodex infestation. Compared with DED, DM has higher priority association with OS Demodex infestation, and patients with both diseases have a significant higher risk of OS Demodex infestation (R = 0.197, P < 0.001). Meanwhile, age (R = 0.299, P < 0.001) and hypertension (P < 0.05) were also correlated with OS Demodex infestation. Conclusion This study provides a new evidence-based basis for clinical prevention and management of OS Demodex infestation.

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Knowledge of breast cancer among medical students in Syrian Private University, Syria: a cross-sectional study

BMC Medical Education ◽

10.1186/s12909-021-02673-0 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Hlma Ismail ◽

Mosa Shibani ◽

Hanaa Wael Zahrawi ◽

Ali Fouad Slitin ◽

Mhd Amin Alzabibi ◽

...

Keyword(s):

Breast Cancer ◽

Risk Factors ◽

Medical Students ◽

Clinical Features ◽

Smoking Status ◽

Private University ◽

Cross Sectional Study ◽

General Information ◽

Sectional Study ◽

Cross Sectional

Abstract Background Breast cancer is the most common cancer among women and the second leading cause of cancer death globally. Since early diagnosis is crucial to reducing mortality, high levels of knowledge regarding general information, risk factors, and symptoms are required among healthcare professionals to deliver breast cancer care. This study aimed to determine Syrian medical students’ knowledge about breast cancer in the fields of general knowledge, common clinical features, and risk factors. Methods This cross-sectional study was conducted at the Syrian Private University in October 2019 (Breast Cancer Awareness Month), Damascus, during the Syrian war crisis. Data were collected through self-administered surveys and analyzed using the Statistical Package for Social Sciences version 25.0 (SPSS Inc., United States). The chi-square test was applied to assess the relationship between the level of knowledge and gender. One way analysis of variance was performed to assess the overall differences in mean knowledge score by study year, GPA, mother’s education, and source of information. Unpaired Student’s T-test was used to analyze the differences in mean knowledge scores (continuous variable) based on smoking status and alcohol consumption. Results Of 320 students, 301 completed the questionnaire (response rate = 94.0%), of which 179(59.5%) were males. The study revealed above-average knowledge scores (total mean = 68.4%) regarding breast cancer, general information (71.9%), common clinical features (71.6%), and risk factors (71.6%). Clinical students (4th, 5th, and 6th years) scored higher compared with pre-clinical students (1st, 2nd, and 3rd years). Conclusion This study showed above-average knowledge scores regarding breast cancer. More efforts to correct misinformation, through reassessing the university curriculum and promoting awareness about breast cancer are required.

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