Histomorphological spectrum of central nervous system lesions in a tertiary care hospital

Background: Central nervous system (CNS) lesions show considerable geographic and racial variations with respect to the incidence and their pattern of distribution. CNS neoplasm account for 2% of all cancers. There has been a rapid increase in incidence of CNS tumors. Many non-neoplastic CNS lesions can clinically and radiologically mimic brain tumors and to differentiate them histopathological examination is necessary.Methods: This was a descriptive cross-sectional study of 30 cases, carried out from March 2020 to February 2021, in a tertiary health care hospital. The cases were diagnosed histopathologically and categorized according to the WHO 2021 classiﬁcation.Results: The study included 30 cases. 3 (10%) of them were non-neoplastic while 27 (90%) were neoplastic with glioblastoma and diffuse astrocytoma being the most common. Overall, tumors of neuroepithelial tissue (60%) was the most common entity. Frontal lobe was the most commonly observed site in the neoplastic lesion. Headache was the most common presentation. Age range varied from 7 years to 66 years with the mean age of 32.7 years.Conclusions: The spectrum of neoplastic lesions were astrocytoma, glioblastoma, ependymoma, hemagioblastoma, medulloblastoma, meningioma, non-hodgkins lymphoma, oligodendroglioma, pitutary adenoma, schwannoma and non-neoplastic were A-V malformation, brain abscess, subdural empyema.

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Women with Abnormal Endometrial Pathology: Experienced at a Tertiary Care Hospital in Bangladesh

Journal of Shaheed Suhrawardy Medical College ◽

10.3329/jssmc.v5i1.16198 ◽

2013 ◽

Vol 5 (1) ◽

pp. 11-13

Author(s):

Mst Syeeda Showkat ◽

Lubna Khondker ◽

Shahryar Nabi ◽

Bishwajit Bhowmik

Keyword(s):

Endometrial Hyperplasia ◽

Histopathological Examination ◽

Tertiary Care ◽

Cross Sectional Study ◽

Transvaginal Sonography ◽

Common Disease ◽

Care Hospital ◽

Cross Sectional ◽

Examination Result ◽

Endometrial Pathology

Background: Transvaginal sonography is superior to transabdominal sonography in most cases of pelvic pathology. Objective: This study was undertaken to see the clinicalpathological characteristics of endometrial hyperplasia. Methodology: This cross sectional study was carried out from January 2007 to December 2008 for a period of two years. All suspected cases of endometrial hyperplasia were included for this study. Transvaginal sonography (TVS) performed and confirmation was done by histopathological examination. Result: A total number of 40 cases were enrolled for this study. The most common diagnosed endometrial pathology was endometrial hyperplasia which was 42.5% cases. Endometrial polyp was diagnosed in 32.5% cases. Endometrial carcinoma was in 7.5% patients and submucosal fibroid was in 10.0%. Conclusion: Endometrial hyperplasia is the most common disease among the women presented with endometrial pathology. DOI: http://dx.doi.org/10.3329/jssmc.v5i1.16198 J Shaheed Suhrawardy Med Coll, 2013;5(1):11-13

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Cervical Cancer Screening On 1000 Healthy Asymptomatic Women Residing In Slum of Rajshahi City of Bangladesh

Journal of Shaheed Suhrawardy Medical College ◽

10.3329/jssmc.v7i1.31784 ◽

2017 ◽

Vol 7 (1) ◽

pp. 14-17

Author(s):

Munira Ferdausi ◽

Fatema Ashraf ◽

Nourin Rahman ◽

Zara Rahman ◽

Fahima Mustanzid

Keyword(s):

Tertiary Care Hospital ◽

Histopathological Examination ◽

Cervical Screening ◽

Tertiary Care ◽

Cross Sectional Study ◽

Care Hospital ◽

Cross Sectional ◽

Study Population ◽

Asymptomatic Women ◽

Rajshahi City

Background: Cervical carcinoma is an important cause of mortality among adult women.Objective: The purpose of the present study was to detect the pre-cancerous condition of cervix in women.Methodology: This cross sectional study was carried out in the OPD of a tertiary care hospital of Rajshahi City in Bangladesh during the year June 2010 to August 2011. Healthy asymptomatic women residing in slum of Rajshahi city with a marital age of 8 years and above were included as study population. VIA test was performed in all women. The VIA positive cases were invited for colposcopy and directed biopsies were obtained from women who were colposcopically positive.Result: A total number of 1000 women were studied. Among them 80(8%) women were VIA positive. These positive cases were also referred for colposcopy. Out of the 80 cases, 26 (32%) were colposcopically normal and 50(63%) were CIN-1 and 4(5%) women were CIN II. Directed biopsy was done among colposcopically positive group. Histopathological examination shows 44 (82%) were CIN-1 and 4(7%) were CIN- II and 6(11%) were chronic cervicities.Conclusion: Cervical screening of the slum area women shows an important number of women suffering from precancerous condition of which CIN-l is the most common.J Shaheed Suhrawardy Med Coll, 2015; 7(1):14-17

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Clinico-etiological study of erythroderma cases from tertiary care hospital, Chitradurga, Karnataka, India

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20202655 ◽

2020 ◽

Vol 6 (4) ◽

pp. 502

Author(s):

Harish Gangaraju ◽

Raghu M. T. ◽

Yogendra M. ◽

Virupakshappa H. E. ◽

Ashwini S. ◽

...

Keyword(s):

Age Of Onset ◽

Histopathological Examination ◽

Tertiary Care ◽

Cross Sectional Study ◽

Care Hospital ◽

Drug Induced ◽

College Hospital ◽

Cross Sectional ◽

Female Ratio ◽

Histopathological Correlation

Background: Erythroderma is a cutaneous morphological reaction pattern of skin having many underlying causes and finding the etiology helps in the proper management of erythroderma cases.Methods: A cross sectional study was performed at the department of dermatology, Basaveshwara Medical College, Hospital and Research center, Chitradurga. Authors studied 30 consecutive cases of erythroderma from July 2017 to June 2019 with respect to the epidemiological, clinical and histological data. Clinico-histological correlation was analyzed for etiology of erythroderma.Results: The mean age of onset was 35.03 years with a male to female ratio of 3:2. In addition to erythrema and scaling that were present in all patinets, other co-existent features included were pruritus (43.3%), fever (23.3%), and edema (16.7%). Of the pre-existing dermatoses, psoriasis was the most common (36.6%) disease followed by eczema (26.7%), drug-induced erythroderma (16.7%), colloidan baby (3.3%), pityriasisrubrapilaris (3.3%) and in 13.3% of cases, etiology could not be ascertained. Clinico-histopathological correlation could be established in 73.3% of cases.Conclusions: In all erythroderma cases cutaneous features were identical irrespective of etiology. Detailed history, clinico-histopathological examination and other necessary haematological investigations helps to establish the etiology of erythroderma which helps in further management.

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Clinical Profile of Hoarseness of Voice: A Hospital-Based Cross-Sectional Study

International Journal of Recent Surgical and Medical Sciences ◽

10.1055/s-0041-1734400 ◽

2021 ◽

Author(s):

Nitin Deosthale ◽

Asha Jadia Soni ◽

Sonali Prabhakar Khadakkar ◽

Mateen Khursheed Wani ◽

Kanchan Sandeep Dhote ◽

...

Keyword(s):

Histopathological Examination ◽

Care Center ◽

Tertiary Care ◽

Cross Sectional Study ◽

Clinical Profile ◽

Care Hospital ◽

Sectional Study ◽

Predisposing Factor ◽

Cross Sectional ◽

Male Preponderance

Abstract Introduction Hoarseness is a symptom with a varied etiology ranging from inflammatory condition, benign lesions to malignant lesions. Benign conditions are more common than malignant. Proper knowledge of clinical profile and evaluation is necessary to treat the cause. Objective It was conducted with the aim to study the clinical profile of patients with hoarseness of voice. Materials and Methods It was a descriptive cross-sectional study of 2 years conducted at Department of ENT at Tertiary Health Care Hospital, India. Patients aged above 10 years presenting with hoarseness of voice were included in the study. After detailed history related to sociodemographic particulars, clinical examinations including Hopkin’s rod examination in all patients and direct laryngoscopy, and radiological and histopathological examination were performed whenever indicated. Results Out of total 100 patients, maximum patients (32%) were in the age group of 21 to 30 years. There was slight male preponderance with male:female ratio of 1.17:1. Laborer (29%) was the major group affected in terms of occupation. Most common predisposing factor was smoking (35%). Commonest etiology for hoarseness of voice was chronic laryngitis (20%). Conclusion Hoarseness of voice as a symptom should never be ignored as its etiology may range from simple infection to malignancy. At our tertiary care center majority of patients come from rural area. Most of the etiological factors found in our study were treatable medically or surgically. Early diagnosis is the key to improve the outcome of treatment.

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Histomorphological Study of Lower Gastrointestinal Tract Lesions in Per Rectal Bleeding Cases

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl4.4477 ◽

2020 ◽

Vol 11 (SPL4) ◽

pp. 2361-2365

Author(s):

Atul B Hulwan ◽

Upadhey S R ◽

Pawar S J ◽

Ramesh M Oswal ◽

Dhirajkumar Mane ◽

...

Keyword(s):

Gastrointestinal Tract ◽

Rectal Bleeding ◽

Tertiary Care ◽

Cross Sectional Study ◽

Care Hospital ◽

Lower Gastrointestinal Tract ◽

Cross Sectional ◽

Common Cause ◽

Neoplastic Lesion ◽

The Mean

The present study on the histomorphology of lower gastrointestinal tract lesions in patients presenting with per rectal bleeding was two years (June 2015 to May 2017) cross-sectional study carried out in the department of pathology of a tertiary care hospital and included 40 cases. Constipation was the most typical associated symptom along with per rectal bleeding. Clinical details and radiological investigations helped in making the diagnosis of all lesions of the lower gastrointestinal tract causing per rectal bleeding. The mean age at presentation in benign lesions was 33 years, while the mean age at presentation in malignant lesions was 61 years. The mean age at presentation of adenocarcinoma was 62 years. Majority of cases of adenocarcinoma presented with Astler-Coller stage C1. The other malignancies of the lower gastrointestinal tract causing per rectal bleeding were clonogenic carcinoma, neuroendocrine carcinoma and moderately differentiated squamous cell carcinoma. The most common cause of per rectal bleeding amongst the lower gastrointestinal tract is a neoplastic lesion. The lesions of the lower gastrointestinal tract causing per rectal bleeding are seen more commonly in male patients with a predominant age group of above 40 years, and constipation is the most typical associated symptom in these cases. The most common cause of per rectal bleeding amongst the lower gastrointestinal tract is a neoplastic lesion.

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Histopathological Study of Myometrial Lesions of Uterus in a Tertiary Care Hospital of South India

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2021/57 ◽

2021 ◽

Vol 8 (06) ◽

pp. 293-297

Author(s):

Gayathri B.N ◽

Mallikarjun A. Pattanashetti ◽

Priyadarshini M.M

Keyword(s):

Histopathological Examination ◽

Tertiary Care ◽

Abnormal Uterine Bleeding ◽

Cross Sectional Study ◽

Histopathological Study ◽

Care Hospital ◽

Age Group ◽

Cross Sectional ◽

Microscopic Pathology ◽

Age Range

BACKGROUND The most commonly done gynaecological surgery worldwide is hysterectomy. Myometrial lesions contribute to majority of cases with abnormal uterine bleeding. Leiomyoma and adenomyosis are most common lesions seen in the myometrium. The present study was undertaken to identify the various types of myometrial pathologies in hysterectomy samples. METHODS This is a two-year retrospective cross-sectional study done from January 2017 to December 2018, in the Department of Pathology, Kodagu Institute of Medical Sciences, Madikeri. All the patients who underwent hysterectomy and myomectomy for myometrial lesions of uterus were included in the study. Hysterectomy specimens showing secondaries, gross infection, massive haemorrhage and necrosis were excluded from the study. Gross appearance and microscopic pathology were noted and results were analysed. RESULTS In this study, 148 specimens were included. Age range was from 20 years to 65 years. Histopathological examination revealed that 58.25 % of myometrial lesions were present in the age group of 41 to 50 years followed by age group of 31 to 40 years. Histopathological examination done showed the following diagnosis in patients - leiomyoma (85.13 %), adenomyosis (8.79 %) and leiomyoma with adenomyosis (6.08 %). CONCLUSIONS The commonest histopathological lesion in myometrium was leiomyoma (85.13 %) followed by adenomyosis (8.79 %). It is mandatory to examine the hysterectomy specimens adequately to diagnose myometrial lesions. KEYWORDS Myometrium, Leiomyoma, Adenomyosis

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