scholarly journals Congenital choledochal malformations in children: management strategies

2017 ◽  
Vol 4 (11) ◽  
pp. 3705
Author(s):  
Jiledar Rawat ◽  
Sudhir Singh ◽  
Digamber Chaubey
Keyword(s):  
Clinical Presentation ◽  
Operative Procedure ◽  
Management Strategies ◽  
Acute Cholangitis ◽  
Previous History ◽  
Biliary Tree ◽  
Definitive Treatment ◽  
Bilioenteric Anastomosis ◽  
Cyst Excision ◽  
History Of

Background: A Congenital Choledochal Malformations (CCM) is common congenital defect of biliary tree in Asian subcontinent. Presentations of CCM are vague from asymptomatic to life threatening cholangitis or pancreatitis. Complete cyst excision and bilioenteric anastomosis is now accepted surgical treatment.Methods: This is a retrospective study of five years duration. In this study the clinical presentation, haematological, biochemical and radiological findings, operative procedure and outcome were studied from case records.Results: Total of 20 patients were studied, with clinical presentation of recurrent abdominal pain in eight cases, previous history of cholangitis in five cases, acute cholangitis two cases, biliary peritonitis in four cases and previous history of pancreatitis in one case. In 13 cases Roux-en-Y hepaticojejunostomy (RYHJ) and in 4 cases hepaticoduodenostomy (HD) done after cyst excision. One case of type II CCM managed with only cyst excision, in two cases Lilly’s procedure, one case requires temporary external drainage and in two cases temporary internal drainage done in view on cholangitis and jaundice.Conclusions: However, the definitive treatment of CCM is complete cyst excision and bilioenteric anastomosis, though lot of other temporary majors are also required at different stages of disease.

scholarly journals Ectopic pregnancy in a tertiary care centre of Jharkhand, India

2019 ◽  
Vol 8 (8) ◽  
pp. 2969
Author(s):  
Meetali Parashar ◽  
Meena Mehta
Keyword(s):  
Ectopic Pregnancy ◽  
Clinical Presentation ◽  
Previous History ◽  
First Trimester ◽  
Near Miss ◽  
Obstetrics And Gynaecology ◽  
Maternal Morbidity And Mortality ◽  
History Of ◽  
Β Hcg ◽  
A Prospective Study

Background: Ectopic pregnancy is one in which the fertilized ovum is implanted and develops outside the endometrial cavity. It is an important cause of maternal morbidity and mortality in first trimester. The present study was conducted to study the risk factors, clinical presentation and management of ectopic pregnancy in RIMS, Ranchi, Jharkhand, India.Methods: This was a prospective study conducted in the department of obstetrics and gynaecology, RIMS, Ranchi, Jharkhand during May 2017 to September 2018. A total of 90 cases were included in the study.Results: 80% of the patients presented with amenorrhoea, 98% had abdominal pain and 69% had vaginal bleeding. Ultrasonography revealed hemoperitoneum in about 93% patients. 16 (18%) patients had history of infertility whereas 10 patients (11%) had taken treatment of infertility.6 (7%) patients had history of STD or PID.14 (16%) had undergone bilateral tubectomy.2 (2%) had history of IUCD insertion and 12 (13%) patients had undergone previously lscs. 54 patients (60%) had undergone D and C and 6 patients (7%) had a previous history of ectopic pregnancy. 68 (76%) underwent only salpingectomy.12 (13%) had salpingo-oophorectomy and 10 (11%) had salpingectomy with contralateral tubectomy.Conclusions:Diagnosis of ectopic pregnancy requires clinical suspicion and supportive investigations like UPT, ultrasonography, β HCG and laparoscopy. It is an important cause of admission to RIMS as maternal near miss cases.Background: Ectopic pregnancy is one in which the fertilized ovum is implanted and develops outside the endometrial cavity. It is an important cause of maternal morbidity and mortality in first trimester. The present study was conducted to study the risk factors, clinical presentation and management of ectopic pregnancy in RIMS, Ranchi, Jharkhand, India.Methods: This was a prospective study conducted in the department of obstetrics and gynaecology, RIMS, Ranchi, Jharkhand during May 2017 to September 2018. A total of 90 cases were included in the study.Results: 80% of the patients presented with amenorrhoea, 98% had abdominal pain and 69% had vaginal bleeding. Ultrasonography revealed hemoperitoneum in about 93% patients. 16 (18%) patients had history of infertility whereas 10 patients (11%) had taken treatment of infertility.6 (7%) patients had history of STD or PID.14 (16%) had undergone bilateral tubectomy.2 (2%) had history of IUCD insertion and 12 (13%) patients had undergone previously lscs. 54 patients (60%) had undergone D and C and 6 patients (7%) had a previous history of ectopic pregnancy. 68 (76%) underwent only salpingectomy.12 (13%) had salpingo-oophorectomy and 10 (11%) had salpingectomy with contralateral tubectomy.Conclusions: Diagnosis of ectopic pregnancy requires clinical suspicion and supportive investigations like UPT, ultrasonography, β HCG and laparoscopy. It is an important cause of admission to RIMS as maternal near miss cases.

scholarly journals Predictive factors for developing acute cholangitis and cholecystitis in patients undergoing delayed cholecystectomy: a retrospective study

2019 ◽  
Author(s):  
Takashi Miyata ◽  
Daisuke Matsui ◽  
Yuta Fujiwara ◽  
Hiroto Saito ◽  
Yoshinao Ohbatake ◽  
...  
Keyword(s):  
Risk Factor ◽  
Surgical Outcomes ◽  
Intraoperative Complications ◽  
Acute Cholangitis ◽  
Previous History ◽  
Cell Counts ◽  
Number Of Patients ◽  
History Of ◽  
Group A ◽  
Group B

Abstract Background We evaluated the risk of acute cholangitis and cholecystitis while waiting for cholecystectomy for gallstones. Methods We retrospectively enrolled 168 patients who underwent cholecystectomy for gallstones after a waiting period and conservative therapy between April 2014 and March 2018 at our hospital. We compared the clinical data from 20 patients who developed acute cholangitis and cholecystitis while waiting for cholecystectomy (group A) with data from 148 patients who did not develop cholangitis and cholecystitis (group B). The risk factors for developing acute cholangitis and cholecystitis and all patients' surgical outcomes were investigated. Results Preoperatively, significant differences in age (68.6 years vs 60.7 years; p= 0.004) and the number of patients with a previous history of acute grade II or III cholecystitis (55.0% vs 10.8%; p< 0.001) and biliary drainage (20.0% vs 2.0%; p= 0.004) were observed between group A and group B, respectively. Preoperative white blood cell counts (13500/µL vs 8155/µL; p< 0.001) and serum C-reactive protein levels (12.6 mg/dL vs 5.1 mg/dL; p< 0.001) were significantly increased, and serum albumin levels (3.2 g/dL vs 4.0 g/dL; p< 0.001) were significantly decreased in group A vs group B, respectively. Gallbladder wall thickening (≥ 5 mm) (45.0% vs 18.9%; p= 0.018), incarcerated gallbladder neck stones (55.0% vs 22.3%; p= 0.005), and abscess around the gallbladder (20.0% vs 1.4%; p= 0.002) were seen significantly more frequently during imaging in group A vs group B, respectively. Furthermore, investigating patients' surgical outcomes revealed a higher conversion rate to open surgery (20.0% vs 2.0%; p= 0.004), longer operation time (137 min vs 102 min; p< 0.001), and a higher incidence of intraoperative complications (10.0% vs 0%; p= 0.014) in group A vs group B, respectively. Conclusions Our results suggest that a history of severe cholecystitis is a risk factor for developing acute cholangitis and cholecystitis in patients waiting for surgery, and a risk factor for increased surgical difficulty.

Mammary Dysbiosis and Nipple Blebs Treated With Intravenous Daptomycin and Dalbavancin

2019 ◽  
Vol 36 (2) ◽  
pp. 365-368 ◽  
Author(s):  
Katrina B. Mitchell ◽  
Anne Eglash ◽  
Ethan T. Bamberger
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Clinical Presentation ◽  
Breast Surgery ◽  
Management Strategies ◽  
Left Breast ◽  
Drug Resistant ◽  
Intravenous Antibiotic ◽  
Methicillin Resistant ◽  
History Of

Introduction Mammary dysbiosis, also known as subacute mastitis, may be associated with nipple blebs. These overlapping diagnoses represent a challenging clinical scenario during lactation. Little research has been published on etiology, management strategies, and outcomes of these concurrent diagnoses. Main issue We document the treatment and outcome of a patient who presented with left-breast dysbiosis and nipple blebs and whose milk culture grew multi-drug-resistant, methicillin-resistant Staphylococcus aureus. She was treated safely and effectively with intravenous daptomycin and dalbavancin. This has not been described previously in the lactation literature. Management The 35-year-old lactating gravida 3, para 3 patient presented at 6 months postpartum to a breast surgery clinic with a 1-week history of worsening deep left-breast pain, blebs, and recurrent plugging. She was afebrile and she had no erythema or induration on her breast exam. A culture of her milk grew multi-drug-resistant, methicillin-resistant Staphylococcus aureus, and she was referred to infectious disease for assistance with intravenous antibiotic therapy. She continued to feed expressed milk throughout treatment and demonstrated complete resolution of symptoms 8 weeks later. Conclusions We report that in patients with a multi-drug-resistant, methicillin-resistant Staphylococcus aureus–positive human milk culture and a clinical presentation of mammary dysbiosis and nipple blebs, intravenous daptomycin and dalbavancin may be an effective treatment.

scholarly journals Peritonsillar Abscess: The Rationale for Interval Tonsillectomy

2000 ◽  
Vol 79 (3) ◽  
pp. 206-209 ◽  
Author(s):  
V.V. Raut ◽  
M.W. Yung
Keyword(s):  
United Kingdom ◽  
Patient Outcomes ◽  
Management Strategies ◽  
Peritonsillar Abscess ◽  
The Other ◽  
Definitive Treatment ◽  
The United Kingdom ◽  
History Of ◽  
Wait And See ◽  
Survey Responses

Although peritonsillar abscess (quinsy) and peritonsillitis are common ENT emergencies, management strategies in the United Kingdom still vary among otolaryngologists. In order to obtain data on the success of the various strategies, we conducted two surveys—one concerned itself with patient outcomes, while the other sought information on physician preferences. The survey of 571 practicing ENT surgeons revealed that 83% advise interval tonsillectomy only for patients who have a history of tonsillitis; they prefer to take a wait-and-see approach for a single attack of quinsy. Conversely, 15% advise a routine interval tonsillectomy following even a single isolated attack of quinsy/peritonsillitis. Only 6.8% still perform a quinsy tonsillectomy in selected cases. Survey responses from 192 adults and 15 children who had been hospitalized for the treatment of quinsy/peritonsillitis revealed that the vast majority of patients who did not undergo an interval tonsillectomy were still asymptomatic 2 to 8 years later. These results indicate that a wait-and-see policy is indeed suitable for most patients who present with an isolated attack of quinsy/peritonsillitis without a history of tonsillitis. We recommend that tonsillectomy be performed as a definitive treatment for quinsy/peritonsillitis in patients who have a history of tonsillitis. Such a history is a reliable indicator of recurrent quinsy or tonsillitis following an attack of quinsy/peritonsillitis in both children and adults. Quinsy tonsillectomy should be reserved for those few patients who do not respond to conservative measures.

scholarly journals Hashimoto’s Encephalopathy Presenting with Acute Behavioral Disturbances: A Case Report

2020 ◽  
Vol 4 (4) ◽  
pp. 309
Author(s):  
Rozi NR ◽  
RM Yousuf ◽  
Kok HT ◽  
Mohd Unit H ◽  
Ibrahim KA ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Previous History ◽  
Acute Onset ◽  
Neurological Deficits ◽  
Cns Infection ◽  
Behavioural Disturbance ◽  
Behavioral Disturbances ◽  
Hashimoto’S Encephalopathy ◽  
Intravenous Acyclovir ◽  
History Of

Hashimoto’s encephalopathy (HE) is a rare and poorly understood neuropsychiatric illness of presumed autoimmune origin, with elevated titres of anti-thyroid antibodies. Its clinical presentation is highly variable that mimic a variety of neurologic and/or psychiatric disorders. Clinical presentation often suggests an infectious etiology which often leads to a mistaken diagnosis. We present the case of 35 year-old female who presented with acute onset behavioural disturbance of one day duration. On examination she was unkempt, emotionally labile, appeared withdrawn and unable to respond to questions. She had no focal neurological deficits. CNS infection was suspected and lumbar puncture was suggested, which the family members refused.She was empirically treated with intravenous acyclovir and ceftriaxone.Metabolic disorder, infectious and toxic issues were ruled out through laboratory testing.In view of her previous history of hyperthyroidism, suspicion of Hashimoto encephalopathy arose.The diagnosis was supported by the elevated level of anti-thyroglobulin (TG) antibody.We report this case to increase its awareness as it is one of the few treatable and easily reversible causes of acute encephalopathy. It should be considered in the differential diagnoses in any patient who presents with acute behavioural disturbance and has concurrent thyroid disorder.International Journal of Human and Health Sciences Vol. 04 No. 04 October’20 Page : 309-312

scholarly journals Gall stone ileus- a rare cause of intestinal obstruction: a case report and review of literature

2017 ◽  
Vol 4 (4) ◽  
pp. 1484 ◽  
Author(s):  
Senthilkumar Perumal
Keyword(s):  
Intestinal Tract ◽  
Clinical Presentation ◽  
Operative Procedure ◽  
Gall Stone ◽  
Review Of Literature ◽  
History Of Surgery ◽  
Radiological Features ◽  
High Incidence ◽  
History Of ◽  
Gall Stone Ileus

Gall stone ileus is an uncommon and potentially serious complication of cholelithiasis. The formation of fistula between the gallbladder and duodenum may allow the gallstone to enter the intestinal tract. It carries a significant morbidity and mortality due to the advanced age of patients and high incidence of concomitant diseases. Here we report a case of a 75-year-old male patient who is a known diabetic, hypertensive and COPD with a recent history of surgery for obstructed umbilical hernia. He presented in the emergency department with small bowel obstruction owing to a large stone in ileum. The clinical presentation, radiological features, operative procedure and literature review are presented.

scholarly journals International Multicentre Study of Candida auris Infections

2021 ◽  
Vol 7 (10) ◽  
pp. 878
Author(s):  
Nirav Pandya ◽  
Yasemin Cag ◽  
Nenad Pandak ◽  
Abdullah Umut Pekok ◽  
Aruna Poojary ◽  
...  
Keyword(s):  
Multicentre Study ◽  
Antifungal Therapy ◽  
Management Strategies ◽  
Previous History ◽  
Significant Risk ◽  
Source Control ◽  
Infection Prevention And Control ◽  
Duration Of Treatment ◽  
Candida Auris ◽  
History Of

Background:Candida auris has emerged globally as a multi-drug resistant yeast and is commonly associated with nosocomial outbreaks in ICUs. Methods: We conducted a retrospective observational multicentre study to determine the epidemiology of C. auris infections, its management strategies, patient outcomes, and infection prevention and control practices across 10 centres from five countries. Results: Significant risk factors for C. auris infection include the age group of 61–70 years (39%), recent history of ICU admission (63%), diabetes (63%), renal failure (52%), presence of CVC (91%) and previous history of antibiotic treatment (96%). C. auris was commonly isolated from blood (76%). Echinocandins were the most sensitive drugs. Most common antifungals used for treatment were caspofungin (40%), anidulafungin (28%) and micafungin (15%). The median duration of treatment was 20 days. Source removal was conductedin 74% patients. All-cause crude mortality rate after 30 days was 37%. Antifungal therapy was associated with a reduction in mortality (OR:0.27) and so was source removal (OR:0.74). Contact isolation precautions were followed in 87% patients. Conclusions:C. auris infection carries a high risk for associated mortality. The organism is mainly resistant to most azoles and even amphotericin-B. Targeted antifungal therapy, mainly an echinocandin, and source control are the prominent therapeutic approaches.

Hot Bathtub, Cold Consequences—Misleading Wounds After Scald Injuries: A Retrospective Analysis

2020 ◽  
Author(s):  
Alperen S Bingoel ◽  
Nicco Krezdorn ◽  
Andreas Jokuszies ◽  
Khaled Dastagir ◽  
Peter Maria Vogt ◽  
...  
Keyword(s):  
Surface Area ◽  
Clinical Presentation ◽  
Previous History ◽  
The Elderly ◽  
Initial Assessment ◽  
P Value ◽  
Significant Difference ◽  
History Of ◽  
Erythematous Skin ◽  
The Mean

Abstract Scalds in the elderly are frequently associated with the use of a bathtub and a disturbed consciousness. Therefore, the total burn surface area is often high. The initial clinical presentation displays a stark erythema of the skin, which frequently does not represent the true depth. The aim of this study was to characterize and assess medical features and outcome of scalds sustained in the bathtub. We conducted a retrospective study at a burn intensive care unit (BICU) between 2011 and 2018. Medical features as well as the treatment in these patients were statistically analyzed. We identified 16 patients and divided them into two groups regarding survival and lethality. The mean total burn surface area was 37.50 ± 19.47%. In 81.25% of the patients, we found a previous history of neurological or psychiatric disorders. Dementia and alcohol abuse were the most common triggers for the trauma. The statistical analysis showed a significant difference for the ABSI-score and the presence of multi organ failure (P-value .0462, respectively, .0004). Erythematous skin areas tended to progress into full thickness burns. We, therefore, coined the term “lobster redness” for these regions. Scalds sustained in the bathtub are devastating injuries. Initial assessment can be misleading and might delay early necrectomy. The wounds request even more attention, if the injuries occurred due to unconsciousness because of the longer exposure to heat. Early necrectomy should be considered. A biopsy with histological workup can be useful. Furthermore, we recommend special safety precautions for neurologically and psychiatrically affected patients.

scholarly journals Abdominal incisional hernia: retrospective study

2018 ◽  
Vol 6 (9) ◽  
pp. 2990
Author(s):  
Archana Shukla ◽  
Sameer Ahmed
Keyword(s):  
Retrospective Study ◽  
Incisional Hernia ◽  
Clinical Presentation ◽  
Previous History ◽  
Age Group ◽  
Precipitating Factors ◽  
Medical College ◽  
Operative Complications ◽  
History Of ◽  
Gandhi Medical College

Background: Incisional hernia presents as herniation or protrusion occurring along a prior abdominal scar. It is a known complication of abdominal surgery. They are the second most common type of hernia after inguinal hernias. This study was undertaken to study the incidence and various risk factors leading to incisional hernia.Methods: It is a retrospective study done in Gandhi Medical College, Bhopal; Department of Surgery during January 2017 to January 2018. All the cases were analyzed in various aspects like age, sex, relative incidence, clinical presentation, nature of previous operation, site of previous scar, precipitating factors like obesity, wound infection, abdominal distension.Results: The incidence is around 18.5%. Patients in the age group of 30-50 years found to have highest incidence of incisional hernia. Females outnumbered the males with the ratio of 6:1. Incisional hernia was more common in patients with previous history of gynecological operation. Most of the patients presented with incisional hernia in the infra umbilical region.Conclusions: Incisional hernias can be prevented by avoidance of midline incisions, especially in the infra umbilical region. Mesh repair results in less post-operative complications provided drains are used.

scholarly journals A Comparative Study of Characteristics and Outcomes of Patients with Proved and Suggested Sarcoid Uveitis Occurring after Ophthalmic Procedure

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Yvan Jamilloux ◽  
Aude Taleb ◽  
Audrey De Parisot ◽  
Laurent Pérard ◽  
Carole Burillon ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Previous History ◽  
Control Group ◽  
Disease Course ◽  
Significant Difference ◽  
History Of ◽  
Potential Trigger ◽  
Incident Cohort ◽  
New Onset

Purpose. To describe patients with new onset sarcoid uveitis occurring after an ophthalmic procedure and compare them with patients with sarcoid uveitis without ocular procedure. Methods. Retrospective analysis of case records from patients with postophthalmic procedure sarcoid uveitis seen at our institution between April 2004 and October 2016. Patients with a previous history of uveitis were not included. Each patient was randomly matched with four controls from our incident cohort of new onset sarcoid uveitis without ophthalmic procedure. Results. We identified 11 patients (8.5%) from our incident cohort of sarcoid uveitis (n=130), who were all women, with a postophthalmic procedure uveitis (mostly after cataract surgery (36%)). These patients were older (69.7 vs 52.7 years) and presented more synechiae than controls. After a mean follow-up of 30 (3–60) months, there was no significant difference between the postprocedure and the control group with regard to demography, clinical presentation, disease course, treatment, and outcome. Conclusions. Sarcoid uveitis has similar characteristics in patients with new onset sarcoid uveitis after or without ophthalmic procedure. As a consequence, ophthalmic intervention should be seen as a potential trigger of latent sarcoidosis.

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