Histopathological study of ovarian lesions in a tertiary care center in Hyderabad, India: a retrospective five-year study

Background: The aim of the study was to identify the pattern of pathologies involving ovarian mass lesions which were received for histopathological evaluation at a tertiary hospital in Hyderabad, Telangana, India during the period January 2012 to December 2016.Methods: The data pertaining to samples of ovarian lesions received for histopathological evaluation at the laboratory of a tertiary care hospital in Hyderabad from January 2012 to December 2016, were analyzed to determine the pattern of pathologies diagnosed during such evaluation and the age distribution of all lesions.Results: Non-neoplastic lesions of the ovary constituted 44.0% of all cases received; follicular cysts constituted 45.5% of these lesions. Malignant lesions constituted only 2.0% of all pathologies. Serous cystadenoma of the ovary constituted the predominant neoplastic lesion diagnosed (62.5% of all neoplastic lesions). 53.2% of patients whose samples were received belonged to the age group of 20-39 years. 90.8% of the lesions were unilateralConclusions: The majority of ovarian lesions received for evaluation were benign and unilateral. Most patients were in the third to sixth decades of life.

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Histopathological Study of Cystoscopic Bladder Biopsies in a Tertiary Care Center

Birat Journal of Health Sciences ◽

10.3126/bjhs.v6i1.37565 ◽

2021 ◽

Vol 6 (1) ◽

pp. 1310-1314

Author(s):

Rachana Dhakal ◽

Hem Nath Joshi ◽

Ramesh Makaju ◽

Shailendra Sigdel

Keyword(s):

Urinary Bladder ◽

Urothelial Carcinoma ◽

Pathological Condition ◽

Care Center ◽

Tertiary Care ◽

University Hospital ◽

World Health ◽

Histopathological Study ◽

Neoplastic Lesion ◽

Neoplastic Lesions

Introduction: Non-neoplastic urinary bladder lesions are not life threatening, but are an important source to cause clinical symptoms and signs. However, neoplasms of the bladder are a source of morbidity, mortality, and exhibit more clinical challenges. Cystoscopy provides overall information about an anatomical/pathological condition of the urinary bladder which will be helpful for patients' management. A cystoscopic biopsy is a primary diagnostic tool for diagnosing urinary bladder cancer. Objectives: The objective of the study was to find the frequency and histomorphological characteristics of urinary bladder lesions in Dhulikhel Hospital, to find the clinical presentation of urinary bladder lesions and to grade the urothelial tumors based on the World Health Organization (WHO)/ International Society of Urological Pathology (ISUP) classification 2004. Methodology: This was a retrospective, cross-sectional, observational study carried out in the Department of Pathology, Dhulikhel Hospital-Kathmandu University Hospital. Convenient sampling was done. All cystoscopy biopsies received from January 2014 to December 2018 were studied. All tissue blocks were retrieved, cut, and stained with Hematoxylin and Eosin. The stained slides were examined under a light microscope by the primary investigator. Result: A total of 70 cystoscopic biopsies were analyzed. The majority of patients 20 (28.6%) were in the age group between 60 and 69 years and males were predominant 43 (61.4%). The neoplastic lesions constituted 40 (57.1%) of all bladder lesions, among them urothelial carcinoma accounted for 38 (54.2%). Similarly, chronic cystitis 27(38.6%) was the most common non-neoplastic lesion. Conclusion: The study found that the neoplastic lesions were commonly encountered in urinary bladder lesions. Among them, lowgrade urothelial carcinoma was the most common bladder tumor. However, most of the non-neoplastic lesions were inflammatory in origin. Cystoscopy combined with histomorphological examination helps in the early detection of bladder lesions.

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Histopathological Study of Ovarian Lesions at a Tertiary Health Care Institute

MVP Journal of Medical Sciences ◽

10.18311/mvpjms/0/v0/i0/724 ◽

2017 ◽

Vol 4 (1) ◽

pp. 26 ◽

Cited By ~ 1

Author(s):

Amod Sawant ◽

Suresh Mahajan

Keyword(s):

Health Care ◽

Hospital Admissions ◽

Tertiary Care ◽

Cystic Teratoma ◽

Serous Cystadenoma ◽

Histopathological Study ◽

Care Hospital ◽

Health Care Centre ◽

Neoplastic Lesion ◽

Benign Cystic Teratoma

Background: Ovary is the commonest site of neoplastic and nonneoplastic lesion, can present in childhood to postmenopausal age group and accounts for the most prevalent cause of hospital admissions. Aim: This study was done to analyse the frequency of ovarian lesions their histological features in a tertiary health care centre. Materials and Methods: This is a prospective study of 143 ovarian lesions at tertiary care hospital over a period of 3yr. All the relevant data of patients analysed from hospital record file. Results: The total number of ovarian lesions studied during study period was 143 cases, amongst them 110 were non-neoplastic and remaining 33 were neoplastic. The most common non-neoplastic lesion seen was solitary follicular cysts i.e. 77 cases (70%), followed by corpus luteal cysts 14 cases (12.7%). Among the 33 neoplastic ovarian lesions 25(75.7%) cases were benign, 2(6.1%) case was at borderline and 6 (18.2%) cases were malignant. In benign ovarian neoplasm, most commonly seen lesion were serous cystadenoma followed by benign cystic teratoma. In malignant cases, maximum were of serous cystadenocarcinoma, followed by endometrioid carcinoma and 2 cases of sex-cord stromal tumours (fibromas) were observed metastatic tumours. Conclusion: Ovarian lesion possess wide gamut of histology. Specific diagnoses are made on routine gross and histological examination.

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Histopathological spectrum of neoplastic and non-neoplastic breast lesions: A three years study in rural tertiary care center.

International Journal Of Medical Science And Clinical Invention ◽

10.18535/ijmsci/v7i01.09 ◽

2020 ◽

Vol 7 (01) ◽

pp. 4721-4725

Author(s):

Dr. Sanjeev Kumar Singh ◽

Dr. Geeta Maurya ◽

Dr. Pinki Pandey ◽

Dr. Rashmi

Keyword(s):

Invasive Ductal Carcinoma ◽

Ductal Carcinoma ◽

Care Center ◽

Benign Lesion ◽

Tertiary Care ◽

Age Distribution ◽

Morbidity And Mortality ◽

Histopathological Diagnosis ◽

Breast Lesions ◽

Neoplastic Lesions

Background: Breast tumours are very common cause of morbidity and mortality worldwide specially in developing countries. Breast lesions show broad spectrum of disease patterns in respect to benign, malignant, and non-neoplastic. Breast cancer is one of the most frequently occurring cancer among women. Objective: To study the frequency, age distribution, clinical and histological patterns of neoplastic and non-neoplastic lesions of breast in this rural population. Material and methods: This observational study was conducted over a duration of three years. In which we studied 210 cases of breast lesions. Specimens were received in department of pathology. Grossing, tissue processing, staining done according to standard protocol. Haematoxylin and eosin (H&E) stained sections were examined under microscope to categorise different type of lesions in the form of non-neoplastic and neoplastic. Results: Out of 210 breast lesions, fibroadenoma was the commonest (114 cases) benign lesion. While invasive ductal carcinoma (70 cases) was commonest in malignant category. Non neoplastic lesions stand on third place, study showed 6 cases out of 210 total cases, in which acute mastitis (4 cases) was most common. Benign tumours were mostly seen in 2nd and 3rd decade and malignant tumour mainly in 5th and 6th decade Conclusion: Early histopathological diagnosis of breast lesions is very important to differentiate between benign and malignant lesions. Large number of cases of invasive ductal carcinoma (>33% of all cases) were seen in our study, which is a serious concern. So, generation of awareness among women is need of time to reduce the morbidity and mortality specially in Indian rural setup

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A two-year study on postmenopausal bleeding at a tertiary institute

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20210008 ◽

2021 ◽

Author(s):

Sowmyanarayanan Lavanya ◽

Swetha Munivenkatappa ◽

Anthata Jyothsna Sravanthi

Keyword(s):

Prospective Study ◽

Tertiary Care ◽

Age Distribution ◽

Developed Countries ◽

Tertiary Hospital ◽

Care Hospital ◽

Postmenopausal Bleeding ◽

Medical Problems ◽

Set Up ◽

A Prospective Study

Background: The life expectancy of women shows an increase as a result of which women experience a long postmenopausal phase. Postmenopausal bleeding is a worrisome symptom occurring in 10 % of the women, making them seek a gynaecology opinion at the earliest. Women in developed countries have a predilection for developing endometrial cancer whereas cancer cervix still dominates in the developing countries. This prospective study was carried out on 75 women presenting with postmenopausal bleeding to the gynaecology clinic at a tertiary hospital set up. The study aimed to find the incidence of postmenopausal bleeding, age distribution, causes and different evaluation methods to confirm the diagnosis.Methods: The present study is a prospective study conducted on 75 postmenopausal women reporting with postmenopausal bleeding at the gynaecology clinic at a tertiary care hospital. Results: Menopause was noted above 45 years in 84% of the patients and 16% were in 40-45 years age. Postmenopausal bleeding was observed in 50-60 years in 56% of women and 30% above 60 years. The medical problems associated were hypertension (20%), diabetes (11%), obesity (22%), hypothyroidism (4%). 53 women had benign causes while 22 had malignancy.Conclusions: Benign lesions of the genital tract are common causes of postmenopausal bleeding. Carcinoma cervix and endometrium classically present with postmenopausal bleed. Strong suspicion, thorough evaluation and early diagnosis improve the quality of life and reduce the morbidity and mortality.

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Histopathological spectrum of Cervical Lesion”– two and half Year prospective Study in Tertiary Care Center of Chhattisgarh, India

Tropical Journal of Pathology and Microbiology ◽

10.17511/jopm.2021.i02.01 ◽

2021 ◽

Vol 7 (2) ◽

pp. 65-70

Author(s):

Dr. Pratima Kujur ◽

◽

Dr. Chandrashekhar Indoria ◽

Dr. S. Bagde ◽

Dr. A. Tiwari ◽

...

Keyword(s):

Breast Cancer ◽

Relative Frequency ◽

Care Center ◽

Tertiary Care ◽

Age Distribution ◽

Tertiary Care Center ◽

Cervical Lesions ◽

Indian Women ◽

Common Cancer ◽

Neoplastic Lesion

Introduction: Cervical lesions are the leading cause of morbidity in Indian women and cervicalcancer is the second most common cancer in women worldwide next to breast cancer. Objectives:To study the age distribution, the relative frequency of various cervical lesions and histopathologicalfeatures of cervical lesions. Materials and Methods: This is a two & half years retrospective studyof all cervical biopsies and hysterectomy specimens received from September 2017 to March 2020 inthe department of pathology. Result: In a total of 485 cases studied 359 (74.1%) cases were non-neoplastic, 107(22%) were preinvasive and 19 (3.9%) cases were malignant. Cervicitis was themost common non-neoplastic lesion and squamous cell carcinoma was the most common cancer.Conclusion: Our study highlights a vast spectrum of cervical lesions and therefore early detectionand management of certain lesions can help in reducing morbidity.

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Clinico-pathological and radiological correlation of sino-nasal masses in a tertiary care center

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20202790 ◽

2020 ◽

Vol 6 (7) ◽

pp. 1342

Author(s):

Dimple Sahni ◽

Gagandeep Kaur ◽

Peeyush Verma ◽

Rajwant Kaur ◽

Harpal Singh

Keyword(s):

Histopathological Examination ◽

Care Center ◽

Tertiary Care ◽

Inflammatory Lesion ◽

P Value ◽

Radiological Investigation ◽

Female Ratio ◽

Histopathological Correlation ◽

Neoplastic Lesion ◽

Neoplastic Lesions

Background: The nasal masses are most commonly encountered condition in outpatient department of otorhinolaryngology. The purpose of this study was to show the clinical, radiological and histopathological correlation of sino nasal masses.Methods: This study was conducted on 100 cases with sino nasal masses over a period of 2 years. A provisional diagnosis was made after clinical and radiological investigation which was confirmed with histopathological examination and the findings were correlated. Results: The number of non-neoplastic lesions were more than neoplastic lesions (75% vs 25%). Incidence was highest in the age group of 31-40 year (21%) with male to female ratio of 1.5:1. In our study among non-neoplastic lesion, inflammatory lesion had highest frequency (75%). We found clinical and histopathological correlation in 94.6% cases (p value 0.04). 93.33% cases correlated radiologically and histopathologically (p value 0.04). Conclusions: We concluded that for proper evaluation of sino nasal masses, clinical, radiological, histopathological evaluation should be carried out conjointly. Histopathologic evaluation remains the gold standard.

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Histopathological Spectrum of Nephrectomies - A 10 Year Descriptive Study from a Tertiary Care Center in South India

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2020/565 ◽

2020 ◽

Vol 7 (47) ◽

pp. 2752-2756

Author(s):

Bhavya P. Mohan ◽

Jaylakshmy Payippat Leelamma ◽

Letha Vilasiniamma ◽

Suresh Bhat

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Care Center ◽

Tertiary Care ◽

Age Distribution ◽

Age Groups ◽

Renal Diseases ◽

Malignant Tumours ◽

Neoplastic Lesions

BACKGROUND Nephrectomy is the standard surgical treatment of neoplastic and non-neoplastic lesions in the kidney and provides more insight into the detailed histopathology of renal lesions. We wanted to identify the age groups, gender distribution and different histopathological types and subtypes of non-neoplastic and neoplastic lesions in nephrectomy specimens over a period of ten years. METHODS A retrospective analysis was done over a period of ten years (January 2006 to December 2015). All nephrectomy specimens received in the Department of Pathology, Government Medical College, Kottayam were recorded from histopathology registers and analysed with regard to age, gender and histopathological types. RESULTS A total of 532 lesions was encountered in our analysis. Males (61.8 %) were affected more than females (38.2 %). Lesions were more on the left side (50.8 %) than right side (49.2 %). Non-neoplastic lesions (53 %) outnumbered neoplastic lesions (47 %). Inflammatory and obstructive causes constituted the majority (43.8 %) in non-neoplastic lesions and renal cell carcinoma was the commonest neoplasm (71.2 %). CONCLUSIONS There is a wide age distribution of renal diseases in the present study. Inflammatory and obstructive conditions constituted the most common indication for nephrectomy, followed by malignant tumours. KEYWORDS Renal Cell Carcinoma, Nephrectomy, Pyelonephritis, Simple Renal Cyst, Wilms Tumour

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Sexually Transmitted Infections in A Tertiary Hospital of Kathmandu: A Retrospective Study

Nepal Journal of Dermatology Venereology & Leprology ◽

10.3126/njdvl.v19i2.37686 ◽

2021 ◽

Vol 19 (2) ◽

pp. 44-48

Author(s):

Sushil Paudel ◽

Niraj Parajuli ◽

Sudip Dahal ◽

Sudarshan Paudel

Keyword(s):

Sexually Transmitted Infections ◽

Care Center ◽

Tertiary Care ◽

Public Health Problem ◽

Tertiary Hospital ◽

Cross Sectional Study ◽

Care Hospital ◽

Cross Sectional ◽

Level Of Education ◽

Sexually Transmitted

Introduction: Sexually transmitted infections (STIs) are the diseases that are transmitted by sexual contact if a partner is infected with agent known to cause infection of genitalia. This group of diseases pose a huge public health problem. This study aims to provide an insight on the prevalence of STIs in a tertiary care center dedicated to civil servants. Methods: This is a retrospective cross-sectional study. All patients diagnosed with STI in a dermatology out-patient of Civil Service Hospital, a tertiary care hospital situated in Kathmandu over a period of two years from January 1 2018 to December 30 2019 were included in the study. The diagnosis was made by clinical and laboratory investigations. Results: The total number 157 cases of STIs were enrolled in this study, of which 119 (75.8%) were males and 38(24.2%) were females. The mean age of patients was 27.8±8.8 years, ranging from 15 to 60 years. Seventy three (46.5%) patients were married, while 81 (51.6%) patients were unmarried. Unmarried males were significantly more vulnerable to acquire STIs (p=0.005). Males were having significantly more premarital or extramarital sexual exposures as compared to females (p<0.001). The most common presentation was condyloma acuminata in 84(53.5%) patients. Consistent use of condom was reported only in 3 (2.5%) males and 1 (2.6%) females in this study. No association was noted between the education level attained to the practice of safe sexual methods (p=0.535). Conclusion: The proportion of males was higher than females in our study which might be due to the reluctances of female to see doctor for sexual problems. The level of education did not seem to make people aware of practicing safe sex. Sexual education seems must in all level of education.

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A RETROSPECTIVE ANALYSIS OF HISTOPATHOLOGICAL SPECTRUM OF LESIONS IN NEPHRECTOMY SPECIMENS IN A TERTIARY CARE CENTRE

10.36106/ijsr/1625859 ◽

2020 ◽

pp. 1-3

Author(s):

K. Sitharamaiah ◽

K. Anusha ◽

G.Raja Sekhar ◽

A. Bhagavan ◽

G. Baleswari

Keyword(s):

Tertiary Care ◽

Chronic Pyelonephritis ◽

Care Hospital ◽

Geographical Differences ◽

Tertiary Care Centre ◽

Common Procedure ◽

Neoplastic Lesion ◽

Radiological Data ◽

High Incidence ◽

Neoplastic Lesions

Background: Kidneys can be involved in various pathological processes. Nephrectomy is a common procedure in urological practice. Indications for nephrectomy can display geographical differences in different countries around the world with different urological causes. The aim of the study was to analyse the various lesions in nephrectomy specimens in a tertiary care hospital in Kurnool, Andhra Pradesh, South India and also to know the frequency of lesions according to the age, gender and histology. Materials and Methods: It is a retrospective study, done over a period of 13 years from June 2007 to March 2020 which included 132 nephrectomy cases. Patient information such as age, gender, clinical diagnosis, radiological data such as USG and CT results, gross morphology and microscopic data were recorded from the available data. Results: Of 132 nephrectomy specimens, 55 (41.66%) were males and 77 (58.34%) were females. The mean age was 40.46 years. 99 (75%) nephrectomy specimens showed ‑ non‑neoplastic lesions and 33 (25%) showed neoplastic lesions. The most common non‑neoplastic lesions were chronic pyelonephritis in 62 (46.96%) patients, followed by tuberculous pyelonephritis in 20 (15.15%) patients. RCC (n = 27) was the most common neoplastic lesion. Conclusion: Chronic pyelonephritis remains the most common non-neoplastic cause of nephrectomy. RCC is the most common neoplastic cause of nephrectomy. Tuberculosis has a high incidence in developing countries. Awareness of renal TB is required for the physicians, to suspect this disease in patients with unexplained urinary tract abnormalities, particularly in those with any immunosuppression and those coming from TB-endemic areas.

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Clinicopathological profile of sinonasal masses-a tertiary care centre study in rural India

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20204182 ◽

2020 ◽

Vol 6 (10) ◽

pp. 1821

Author(s):

Vidya Rokade ◽

Kiran J. Shinde ◽

Girishkumar R. More

Keyword(s):

Histopathological Examination ◽

Tertiary Care ◽

Rural India ◽

Histopathological Diagnosis ◽

Care Hospital ◽

Tertiary Care Centre ◽

Radiological Investigation ◽

Male Predominance ◽

Neoplastic Lesion ◽

Neoplastic Lesions

Background: A variety of mass lesions occur within the paranasal sinus (PNS) and nasal cavity and thus it becomes mandatory for otorhinolaryngologist to elicit detailed history and thorough examination before reaching a final diagnosis. This is retrospective study of all sinonasal masses who were undergone surgical management in the institute of rural India and so in the environment.Methods: This is a retrospective observational study of 70 patients with sinonasal masses treated at a rural tertiary care hospital in rural western Maharashtra from period of Jan 2016 to May 2018. History, clinical assessment and histopathological examination (HPE) was done in all cases as per hospital record supplemented by radiological investigation as per requirement. The patients were grouped as per their histopathological diagnosis as non-neoplastic/inflammatory and neoplastic.Results: A total of 70 patients were analysed age ranging (11-70 years). Majority of the patients were in the age groups 21-40 years (47%). There were 43 (61%) male and 27 (39%) female with M:F ratio 1.6:1. On HPE, 50 (71%) cases were non neoplastic/inflammatory and 20 (29%) cases were neoplastic lesions. HPE revealed that 50 (71%) cases were non neoplastic and 20 (29%) cases were neoplastic lesions.Conclusions: Sinonasal masses have various differential diagnoses. They are fairly common with male predominance. Benign conditions show a peak during 2nd to 4th decade of life while malignancy increasing with the age after 4th decade. In non-neoplastic lesion, Allergic nasal polyp is the commonest histological pattern seen while in malignant lesions squamous cell carcinoma is noted with 100% male predominance.

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