scholarly journals A study of hematological parameters and requirement of platelet transfusion in dengue fever

2017 ◽  
Vol 4 (6) ◽  
pp. 1668
Author(s):  
Yashaswini L. S. ◽  
Priya .

Background: Dengue is a common vector-borne disease in India with significant morbidity & mortality. Thrombocytopenia is a common complication in dengue. Bleeding manifestations in dengue put an immense pressure on both patients and treating physicians. There are no clear guidelines for transfusion of platelets in bleeding patients and role of Platelet transfusion in this condition is a bit controversial.Methods: It was an observational study done at Sree Rajarajeswari medical college and hospital between 1st May and 31st July 2016. Total of 100 dengue-positive cases were studied with respect to clinical features, laboratory parameters and requirement of platelet transfusion.Results: Majority of patients were males and in the age group 21-30 years. Fever was present in all cases, with a mean of 3-6 days duration. Epistaxis was the most common bleeding manifestation (43%), Malena being the least (3%). Leucopenia was observed in 52% patients. Thrombocytopenia was seen in 89% of admitted patients and 38% among them had raised aPTT. 53%of patients in our study received platelet transfusion.Conclusions: Bleeding manifestations have no significant association with severity of platelet count. Severe leucopenia is associated with thrombocytopenia. There is no need of platelet-transfusion in all patients with thrombocytopenia with minor bleeds.  

2019 ◽  
Vol 5 (02) ◽  
pp. 42-45
Author(s):  
Luv Luthra ◽  
Rajendra Prasad ◽  
Ranjith Kumar ◽  
Nivedita Mitta ◽  
Tinku Varghese

Abstract Introduction Nonhealing venous ulcers are one of the most common forms of lower extremity ulcers in the present population. It is cumbersome to treat and is associated with high-morbidity and immense treatment expenses. The current treatments include compression therapy. Four-layer compression dressings have proven to be an effective treatment for venous ulcers. Objective This study aimed to evaluate the efficacy of four-layer compression dressings and to study the rate of healing and duration of treatment with four-layer compression dressings. Materials and Methods A prospective randomized study conducted at MS Ramaiah Medical college which included 70 patients who completed the course of weekly dressings depending on the size of ulcer. The regular four-layer dressings were done by a trained podiatrist in vascular outpatient department (OPD) once a week. The area of the ulcer was calculated using the modified Gilmen formula. Results A total of 70 patients who were compliant with the treatment were included in the study. A considerable percentage (74%) of patients were male and all the ulcers were located at the gaiter area. Most belonged to the age group between 41 to 50 years (25%). The healing rate of ulcers at the end of 4, 8 and 12 weeks were 46.87, 28.12, and 25%, respectively. At the end of 12 weeks, all the ulcers healed.


Author(s):  
Nutan Narayan ◽  
Dipti Roy

Aim: to study the effects of teenage pregnancy on obstetrics and neonatal outcome. Materials and methods: The present prospective comparative interventional study was conducted in the Department of Obstetrics and Gynecology, Nalanda Medical College and Hospital, Patna, Bihar. Total 60 patients were divided in to two groups. Results: Majority of the patients (66.9%) were in the 18-20 years of age group. Pre-eclampsia was observed in 26.7% of the patients who didn’t receive vitamin D supplement whereas the group I which received supplementation showed on pre-eclampsia in   6.7% of the patients (p=0.001). Conclusion: This study concludes that there is significant role of vitamin D supplementation in pregnant women in prevention of pre-eclampsia. Keywords: pre-eclampsia, vitamin D, neonatal outcome, teenage


2021 ◽  
Vol 15 (11) ◽  
pp. 3343-3345
Author(s):  
Farrukh Sarfraz ◽  
Sobia Nawaz ◽  
Nadeem Razaq ◽  
Muhammad Saif Ullah ◽  
Zahid Mahmood ◽  
...  

Introduction: Medical education is blended day by day and there's a continuing need to assess the role of the facilitator in the field of medical education. A great medical facilitator is the one who clear the way within the making of our future clinicians. In this study we attempted to assess the qualities of best medical facilitator in basics and clinical sciences including all medical, surgical and their allied subjects from first year to final year MBBS Students Objective: To expedite the views of MBBS students at Azra Naheed Medical College about the best qualities of Medical facilitator Material and Methods Study design: quantitative cross sectional Settings: Azra Naheed Medical College Duration: Six months i.e. 1st January 2021 to 30th June 2021 Data Collection procedure: A well planned study was done at Azra Naheed medical college which includes all the MBBS students who participated after giving consent. The total numbers of participants in the study were 400. A validated questionnaire comprises of 12 leading statements regarding best qualities of medical facilitator was circulated. The collected data was analyzed by using SPSS version 23. Results: The total number of participants in the study is 400 in which 60% participants were females and 40% were males. The age group in the study is 18-24 years. In this study top five qualities of nest medical facilitator were highlighted. Conclusion: A great facilitator is somebody who is receptive, engaging and motivating, and who includes a sound knowledge of subject of what they are attempting to instruct. They too have the capacity to communicate well with students. Key words: Medical facilitator, Student, Medical, Qualities


2019 ◽  
Vol 6 (8) ◽  
pp. 2837
Author(s):  
Yashashvi Choudhary ◽  
Mohit Kumar Patel ◽  
Padmakar K. Baviskar

Background: The specific threshold for prostate-specific antigen (PSA) to delineate patients who are at the highest risk has been controversial. It is wiser to refine PSA by its derivative parameter like PSAD (PSA/vol) which can be used as a better diagnostic tool in early detection of carcinoma of prostrate. To evaluate sensitivity and specificity of PSAD in diagnosis of carcinoma of prostrate.Methods: A study including 70 patients was done in Pravara Medical College and Rural Hospital, Loni. Patients were screened for prostatic diseases by DRE, blood PSA (ng/ml) estimation, prostatic volume by transabdominal ultrasonography and prostatic biopsy by FNAC or Tru cut Biopsy.Results: In the present study maximum incidence of BPH and CaP manifested in the age group of 61-70 (i.e., 35.18%) and Ca prostate were in age group of 71-80 (i.e., 50%). The maximum number of patients with BPH were having PSA values between 3-10 ng/ml, where as in CaP the value varied between 10.1-20 ng/ml. The maximum number of patients were in the range of 3-10 ng/ml in which age group 61-70 were having highest (35.71% of the pts in that range) followed by PSA range 10.1-20 ng/ml in which, age group 71-80 have shown maximum number (54.54% of the pts in that range) . The sensitivity, specificity, accuracy of PSAD in diagnosing malignant prostatic diseases were analysed and values were as follows: sensitivity: 87.50%, specificity: 92.59%.Conclusions: It was concluded that patients with PSAD >0.15 can be advised for prostatic biopsy and regular follow so that appropriate treatment is performed and mortality due to prostatic malignancy is reduced.


Author(s):  
Bijaya K. Behera ◽  
Sathish K. TN

Background: Present study was conducted with an objective to evaluate the role of ADA and lymphocyte/neutrophil ratio in the diagnosis of tuberculous pleural effusion in patients with exudative pleural effusion and to analyze the cause of non-tuberculous exudative pleural effusion.Methods: This hospital based observational study was conducted from August 2011 to September 2013 with a total number of 120 patients of exudative pleural effusion who were admitted in medical wards of MKCG Medical College Hospital, Berhampur, Odisha, India. Patients with transudative pleural effusion, age less than 12years and those who were haemodynamically unstable were excluded from the study. Statistical analysis was done using standard statistical techniques.Results: A total number of 120 patients with exudative pleural effusion were analyzed. 83 patients were males and 37 patients were females. Maximum no of patients were seen in the age group of 21-40 years. Total ADA was found to be >40 U/L in all cases of TB effusion. All cases of TB effusion were lymphocyte predominant with L/N ratio > 0.75. In case of exudative pleural effusion due to non-tuberculous etiology L/N ratio was <0.75. P Value <0.0001 was considered extremely significant for L/N ratio for TB effusion.Conclusions: ADA value more than 100 U/L was observed only in patients of tuberculous effusion. L/N ratio was >0.75 in 97 patients of tuberculous effusion and none of the non-tuberculous effusion. Combined use of ADA and L/N ratio is more efficient means for diagnosing tuberculous pleural effusion than the use of ADA alone.


2016 ◽  
Vol 4 (1) ◽  
pp. 12-15
Author(s):  
Laxmi RC ◽  
Chitra Ranjan Das

Background: Vaginal hysterectomy is one of the most common gynecological procedures performed in Nepal. The most common indication is pelvic organ prolapse (POP). The common complications associated with vaginal hysterectomy are hemorrhage, infections and injury to adjacent organs.Objectives: The aim of this study was to study the type of complications following vaginal hysterectomy in pelvic organ prolapse.Methods: A Prospective observational study was carried out at Lord Buddha Educational Academy Nepalgunj Medical College, Kohalpur, Banke, Nepal from November 2008 to May 2009. A total of 311 patients belonging to age group (20-80) years, presenting to the out-patient department with second to fourth degree utero-vaginal prolapse without any severe medical and surgical problems were included in this study. All the patients who had undergone vaginal hysterectomy during the study period and met the inclusion criteria were included in this study. The data collected was analyzed with standard statistical method (SPSS statistics 16.0).Results: Total of 311 women were included in this study between the age group (20-80 years) with pelvic organ prolapsed (second to fourth degree). All of them underwent vaginal hysterectomy. Among them 39 (12.5%) had complications. The most common complication was secondary haemorrhage accounting for eleven (28.2%) of all complications. Eight (20.5%) patients had retention of urine, four (10.3%) had headache, three (7.7%) patients had primary haemorrhage, three (7.7%) had pelvic cellulitis, three (7.7%) had UTI, three (7.7%) vault abscess, one (2.6%) had bladder injury, one (2.6%) had pelvic peritonitis, one (2.6%) had vault prolapse. We had one death due to septicemia following seven days of post operation.Conclusion: In our study, complication of vaginal hysterectomy was 39 (12.5%) out of 311 patient. The most common complication being secondary haemorrhage 11 (28.2%).Journal of Kathmandu Medical College, Vol. 4(1) 2015, 12-15


Author(s):  
Arpana Dipakbhai Chaudhari ◽  
Anilkumar Mathurbhai Baria ◽  
Upendra Rameshbhai Chaudhari ◽  
Grishma T. Dixit ◽  
Nilesh Thakor

Background: Tubal factor infertility accounts for a large portion of female factor infertility. The most prevalent cause of tubal factor infertility is pelvic inflammatory disease and acute salpingitis. Tubal patency can be diagnosed by hysterosalpingography (HSG) or laparoscopy with chromopertubation. The aim of this study was to determine the role of laparoscopy in the evaluation of tubal factor in infertile women.Methods: Sixty women presenting with complaints of primary and secondary infertility were investigated for tubal disease by laparoscopy at at Smt. NHL Municipal Medical College, Ahmedabad during July 2011 to September 2013. Tubal patency was tested by chromopertubation using Methylene blue dye.Results: Thirty-five (58.3%) patients were in primary infertility group while 25 (41.7%) patients were in secondary infertility group. 80% women were in the age group of 21 to 30 years. In 49% of women, the duration of infertility was between 2 to 4 years whereas 17% cases had been infertile for 6 to 10 years. Diagnostic laparoscopy and findings of chromopertubation revealed unilateral blockage in 37% of cases, bilateral blockage had seen in 23% of cases, endometriosis was seen in 9% of cases and adhesion in 7% of cases.Conclusions: Unilateral and bilateral tubal blockade was detected in 60% of cases of infertile women.


Author(s):  
SACHIDANANDA NAYAK ◽  
BIJAYA KUMAR BEHERA ◽  
KESHABA CHANDRA BUDULA ◽  
SRITAM ACHARYA

Objective: Deliberate self-poisoning is a serious global issue that contributes to significant morbidity and mortality all over the world. The present study was conducted with an objective to identify the common agents used for self-poisoning prevalent in South Odisha and to determine the common clinical features and outcome of such cases. Methods: This cross-sectional observational study was conducted on 200 patients with deliberate self-poisoning belonging to the age group of 15–70 years over a period of 2 years from August 2017 to September 2019 in Maharaja Krishna Chandra Gajapati Medical College and Hospital, Berhampur, Odisha, India. All the above-mentioned patients admitted to the hospital, were treated with specific antidotes according to the poison ingested. Results were analyzed using appropriate standard statistical methods such as mean, standard deviation, and percentage. Results: Out of 200 patients, majority were female (65%, n=130) and 35% (n=70) were male; mean age was 38.9 (±16.8) years. Organophosphates, aluminum phosphide, glyphosate, organochlorines, and carbamates were the most common pesticides used as poisoning agents (74.5%, n=149) followed by plant poisons (7%, n=14) which included yellow oleander seed. Overall mortality in our study was 12.5%. Conclusion: Pesticides and plant poisons were the common agents used in our study for deliberate self-poisoning. Young persons, illiterates, and housewives were commonly involved in suicide attempts. Organophosphate caused majority of deaths.


Author(s):  
Manwendra Kumar ◽  
Sudhir Kumar ◽  
Pankaj K. Chaudhary ◽  
Amit Kumar

Background: Infantile hemangiomas are the most common benign soft tissue tumor of infancy and childhood occurring 4-10% of all infants. It is more frequent in premature children (23% of infants <1200g) and females (3:1 to 5:1). For many hemangiomas treatment is not required, however hemangioma in some locations need treatment to prevent complication. The Present study was done with an Aim to assess the efficacy and safety of oral Propranolol in management of infantile heamangioma in our set-up.Methods: This study was conducted from May 2016 to Nov 2017 at Department of Surgery and Pediatrics, M.L.B. Medical College, Jhansi after obtaining Ethical permission. Patients having confirmed were recruited & admitted for initiation of Oral Propranolol therapy for 5 days under the observation of Paediatrician. Oral Propranolol treatment was continued till the age of 11/2 years. A clinical assessment was made at each visit to the Outpatients Clinic every four weeks.Results: The incidences of infantile hemangioma were more in age group (0-7 months) i.e 55% (22 patients) followed by age group of (8-15 days) i.e. 30% (12 patients). As age advances presentation gradually decreases as after 30 days incidence is only 5%. Infantile hemangioma were more common in females’ patients (55% patients) & mostly 90% (36 patients) present as single lesion and only 10% (4 patients) present as multiple lesions. Most of hemangiomas presented as reddish in color 80% (32 patients) which reflected lesions are mostly superficial & only 10% were brownish red and 10% skin color indicated incidence of deeper penetration.Conclusion: Authors found that drug (Propranolol) to be effective even at low dose of 1mg/kg/day. In our study group it was effective and safe in almost all patients.


Author(s):  
F. K. K. Jasima Nilofer ◽  
Rajalakshmi V. Mary Lilly

Objectives: Pediatric anemia is one of the major health problems in India and in many parts of the world, as it results in reduced exercise tolerance, slower rate of growth, impaired development and cognition, and delayed wound healing. Anemic children are also at a higher risk of death due to complications associated with malnutrition and infection. Aim: To evaluate the clinical features and the basic hematological parameters of anemia in                infants and children, in the age group of 6 months to 14 years. To study the morphological        patterns of different types of anemia on peripheral smear & correlate the corresponding clinical presentation. Methodology: The study was conducted on 100 patients between the age group of 6 months to 14 years in the pediatric ward of Sree Balaji Medical College & Hospital, Chennai. The hematological analysis was made by using automated analyser (Sysmex KX-21 autoanalyser). The complete haemogram was done from Peripheral smears for each participant. The reticulocyte count was done by the supravital staining technique using Brilliant crystal blue. The experiments were done in triplicates and statistical analysed were performed by using Graphpad Prism (Ver.5). Results: The present study showed that anemia was more prevalent among male children than female counterparts and pre- school children were severely affected. The commonest presenting condition was acute gastroenteritis followed by respiratory symptoms. The most common morphological type was microcytic hypochronic anemia and iron deficiency anemia was the most common etiological type. Conclusion: Pediatric anemia is quiet common due to the fact that children are the most vulnerable population for anemia to occur. This compels prompt screening and diagnosis at an early stage through necessary investigations & utilization of available advanced technical modalities in order to initiate timely treatment and management.


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