scholarly journals Profile, types, duration and severity of muscular dystrophy: a clinical study at a tertiary care hospital

2018 ◽  
Vol 5 (3) ◽  
pp. 700
Author(s):  
Viswajyothi P. ◽  
Rambabu M. V.

Background: The cause of muscular dystrophies is genetic. It is a disorder of muscular system. The classification of the muscular dystrophies is based on the signs and symptoms. Present study was done to evaluate the profile, types, duration and severity of muscular dystrophy at a tertiary care hospital.Methods: A hospital based cross sectional study was carried out at department of General Medicine, Malla Reddy Institute of Medical Sciences, Hyderabad from October 2015 to December 2017. During the study period, it was possible to study the 20 cases of muscular dystrophy.Results: Muscular dystrophy was more common in males. Maximum cases were of Duchenne type of muscular dystrophy. Majority of the patients presented at 5-10 years of age. Muscular dystrophy was seen in early childhood. Out of 10 patients of Duchenne muscular dystrophy five patients were of grade I. There was no correlation between the duration of the disease and the severity of the disability. All patients had lower limb proximal weakness. Pathological Q wave (width > 30 ms) and Pathological Q wave (depth >more than 25% of the QRS amplitude) were present in 35% of the cases. All patients had rhythm NSR and QRS +60 to +75. Conduction abnormality was present in 5% of the cases. In half of the patients, serum creatinine kinase levels are moderately elevated.Conclusions: Muscular dystrophies are a common disorder of the childhood. Detailed studies will help to focus more light on this condition to improve outcome in future patients.

2020 ◽  
Vol 7 (09) ◽  
pp. 4981-4985
Author(s):  
Dr Rajendra Kumar ◽  
Dr Prodeep Kumar

Objective :  To find out the role of dyslipedemia as a contributing factor in heart failure cases and study comparatively with the Framingham study (meta analysis). Methods : This was a cross- sectional study conducted in a tertiary care hospital. The study was approved by the ethics committee of the institute and consent was taken from each participant before enrolling in the study.  A total of 100 cases with signs and symptoms of heart failure (Acute/Acute on Chronic and Chronic heart failure) were included in the study. Background : The relationship of lipid concentrations to heart failure has been evaluated in a study derived from Framigham Heart study participants.


Author(s):  
Sumit Wasnik ◽  
Arjun Mehta

Background: Mosquito borne diseases are a serious public health concern in India. The incidence of Mosquito borne diseases is linked with economic and social development of the community. The objectives of the study were to assess the awareness, knowledge and practices about mosquito borne diseases in study population and explore the various myths about mosquito borne diseases among them.Methods: It is a hospital based cross-sectional study and the study participants will be patients getting admitted for any reason and having fever, in the general medicine male and female ward. This study period was 3 month (January to March 2017). Results: Total 150 patients admitted in male and female medicine ward were included in the study out of them 84 were male and 66 were female patients. It was observed that educated participants had more knowledge about mosquitoes borne diseases. Conclusions: Most of the participants didn’t know that clean water could be a source of breeding of mosquitoes. Many myths are prevalent in the study population about mosquitoes borne diseases. 


2021 ◽  
Vol 12 (11) ◽  
pp. 149-155
Author(s):  
Arijit Mondal ◽  
Soumi Ghosh ◽  
Uday Sankar Mandal ◽  
Dwaipayan Saha

Background: According to the previous studies, psychiatric symptoms are high in patients with physical illness, but the referral rates are much below expectation. Aims and Objectives: Here a descriptive cross-sectional study has been conducted using self designed semi structured proforma to asses the socio demographic profile and psychiatric diagnosis of patient with physical illness referred from other departments in a tertiary medical care centre for consultation liaison (C-L) psychiatry care. Materials and Methods: The study population consists of the patients referred to psychiatry department for consultation purpose from all the other departments in a 4 months period. The data were collected on a self designed semi structured pro forma and all the diagnosis were made according to International Classification of Disease -10 (ICD-10) criteria. Analysis has been done using descriptive statistics. Results: A total numbers of 203 patient has been referred to psychiatry department during the study period . Among them 144 were inpatient and 59 were outdoor based referral. Majority were female, married . The maximum referral were from general medicine department followed by neuromedicine. Most common reason of referral being suicidal attempt by different means followed by patients having depressive features .The most common psychiatric diagnosis was depression followed by delirium. Conclusion: C-L psychiatry plays a significant role in better evaluation and management of patients with psychiatric comorbidities referred from non-psychiatric departments.


Vacunas ◽  
2020 ◽  
Vol 21 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Y.M. AlGoraini ◽  
N.N. AlDujayn ◽  
M.A. AlRasheed ◽  
Y.E. Bashawri ◽  
S.S. Alsubaie ◽  
...  

Author(s):  
Nandini Chatterjee ◽  
Supratick Chakraborty ◽  
Mainak Mukhopadhyay ◽  
Sinjon Ghosh ◽  
Bikramjit Barkandaj ◽  
...  

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Nearmeen M. Rashad ◽  
Marwa G. Amer ◽  
Waleed M. Reda Ashour ◽  
Hassan M. Hassanin

Abstract Background Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system with varied clinical features. Disease-modifying drugs (DMDs) of MS associated with different types of thyroiditis. In this cross-sectional study, we aimed to assess the prevalence of thyroid dysfunction in MS and to investigate the association between DMDs and the risk of thyroiditis in MS. A cross-sectional study included 100 patients with relapsing-remitting multiple sclerosis (RRMS) in relapse, and the diagnosed was according to revised McDonald’s criteria 2010. Results Our results revealed that the prevalence of thyroiditis was 40%; autoimmune (34%) and infective (6%) among patients with RRMS in relapse and cerebellar symptoms were significantly higher in patients with thyroiditis compared to patients without thyroiditis. Regarding the association between DMDs and thyroiditis, the prevalence of patients treated with interferon-beta-1b was higher in MS patients with thyroiditis compared to MS patients without thyroiditis. However, the prevalence of patients treated with interferon-beta-1a was lower in MS patients with thyroiditis compared to MS patients without thyroiditis. In addition, we found CMV infection was more common in patients treated by interferon beta-1b and candida infection was common in patients treated by fingolimod. Conclusions Thyroiditis is commonly observed in patients with RRMS in relapse and higher prevalence of patients treated with interferon-beta-1b which is commonly associated with thyroiditis and CMV infection; however, candida thyroid infection was common in MS patients treated by fingolimod.


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