scholarly journals Association between gastroesophageal reflux disease-questionnaire factors and gastroesophageal reflux disease incidence at Kardinah general hospital inpatient wards

2021 ◽  
Vol 8 (2) ◽  
pp. 152
Author(s):  
Darren Gosal ◽  
Rachman Edi Santoso ◽  
Yohanes Firmansyah

Background: Gastroesophageal reflux disease (GERD) is a condition where an acid reflux into the esophagus with can resulted some symptoms. GERD is one of the most common disease in around the world. The most common symptom is heartburn, with its various risk factors. Diagnosing GERD based on the clinical examination or more advanced examination. One simple tool to help diagnosing is GERD questionnaire (GERD-Q). This study aims to find out the association of GERD-Q factors to GERD incidence at Kardinah inpatient wards.  Methods: This study is cross sectional design, with the subjects are all patients in the inpatient wards, and asked with the Indonesian version of GERD-Q plus other questions. All data will be assessed with chi Square test.  Results: Total of 84 respondents are in this study, where the relationship of each factors with GERD incidence are: gender (p value: 0.191), surgery (p value: 0.428), spicy foods consumption (p value: 0.920), fatty foods consumption (p value: 0.916), sour foods consumption (p value: 0.557), and irregular eating habit (p value: 0.023).Conclusions: Irregular eating habit is significantly associated with GERD incidence.

2021 ◽  
Vol 15 (5) ◽  
pp. 1507-1510
Author(s):  
K. H. Samejo ◽  
S. K. Kumar ◽  
G. Lail ◽  
A. B. Langove ◽  
S. Ahsam ◽  
...  

Objective: Gastroesophageal reflux disease (GERD) prevalence ranges from 24% to 35% in Pakistani population. Studies have demonstrated GERD frequency is directly proportional to increasing weight. Thus, the frequency of obesity among gastro esophageal reflux disease patients was determined. Methodology: This cross-sectional study was conducted on outpatients with GERD visiting Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi; from December 2017 to June 2018. Clinical and demographic parameters of study population were recorded. Body mass index (BMI) more than 27 was labeled as obese. Patients with history of ischemic heart disease, pregnancy, ascites and/or Patients on NSAIDS, bisphosphonates or steroids were excluded. Results: One hundred and fifty patients with mean age of 43.3±11.5 years were included in study. Eighty-seven patients (63.3%) had age more than 40 years. Majority of study population were males 95 (63.3%). Mean height and weight of study population were 163.09±9.56 cm and 72.92±15.13 kg, respectively. Mean BMI were 27.55±6.02 in which 71 (47.3%) were obese i.e., BMI >27. Majority were Urdu speaking i.e., 57 (38%) followed by Sindhi 31 (20%) Diabetes mellitus was documented in 22 (14.7%) and hypertension in 16 (10.7%) patients. Statistically significant association of GERD was seen in obese females (p-value: 0.018) Conclusion: Increase frequency of obesity is significantly associated with GERD. More proportion of obese females has GERD. Keywords: Gastro esophageal reflux disease; Body mass index; Weight; height


2011 ◽  
Vol 18 (04) ◽  
pp. 693-696
Author(s):  
ABDUL RAZZAQ WARRAICH ◽  
DR. RAFFAD ◽  
CHAUDHRY MUHAMMAD SIDDIQ ◽  
Zaheer Iqbal ◽  
Mohammad Saeed Khokhar

Objective: To find the frequency of H pylori infection among the patients of gastroesophgeal reflex disease. Study design: Descriptive study. Setting: Department of Medicine, Unit-I, Services Hospital, Lahore. Subject & method: One hundred patients with gastroesophageal reflux disease (GERD) were included in this study. For detection and confirmation of helicobacter pylori, endoscopy with antral biopsy was done. Specimens were sent for histopathology, and rapid urease test was performed. Main outcome measures: Frequency of H pylori infection, frequency of regurgitation, dysphagia, nausea, vomiting and haemetemesis. Results: 100 patients who fulfilled the inclusion criteria were taken. There were 65 males and 35 females respectively. Their age ranged from 18 to 48 years. 39 (39%) patients were between 29-38 years while 23 (23%) were of 39-48 years. There were 38 (38%) patients between 18-28 years. The mean age of the patients was 31.79±7.56. 40 (40%) were found to be H. pylori positive on biopsy and rapid urease test, while 60 (60%) were H. pylori negative. The most common recorded symptom was chest pain/retrosternal burning (90%). Regurgitation (65%) and nausea (55%) were other common symptoms. Dysphagia and water-brash were present in 40% each. Vomiting (30%), abdominal pain (25%) and cough (20%) were the other symptoms. The least common symptom was haemetemesis (5%). Conclusions: A causal relationship between GERD and H. pylori infection could not be established. Therefore, routine H. pylori eradication in the treatment of patients with GERD is not recommended. 


Author(s):  
R. I. Khlynova ◽  
O. M. Khromtsova ◽  
R. B. Berdnikov ◽  
I. B. Khlynov

The aim is to study the effect of Helicobacter pylori infection on risk of developing gastroesophageal reflux disease. Materials and methods - cross-sectional observational study of 1007 patients with dyspepsia syndrome who underwent videoesophagogastroduodenoscopy with biopsy and histological examination of biopsy specimens of the gastric mucosa by OLGA-system. The age, gender, overweight, cigarette smoking, presence of Helicobacter pylori infection and gastritis stage were assessed. Results - the study showed a significant decrease in the incidence of gastroesophageal reflux disease in patients with positive H. Pylori status by 4% (RR 0,68; 95% CI, 0.49-0.94, p=0,041). The risk of developing gastroesophageal reflux disease significantly higher in overweight (RR 2,62; 95% CI 2,0-3,56; р<0,001) men (RR 1,76; 95% CI 1,33-2,32; р=0,0046) who smoked cigarettes (RR 3,23; 95% CI 2,45-4,24; р<0,001) and was not associated with the patient’s age and the stage of gastritis (р>0,05). Conclusion - a significant reduction in the frequency and risk of developing gastroesophageal reflux disease in patients with Helicobacter pylori infection is demonstrated.


2020 ◽  
Vol 50 (4) ◽  
Author(s):  
María Alejandra Mortarini ◽  
Daniela Neder ◽  
Ana Rocca

Motility disorders are frequent in children with cerebral palsy. The prevalence of gastroesophageal reflux disease varies from the 15% to 75% in patients with cerebral palsy. Nissen fundoplication is the most used antireflux technique not without complications in this population. Our objective was to determine the frequency and the characteristics of the long-term functional and motility complications in patients with Nissen fundoplication and cerebral palsy. A descriptive cross-sectional study was performed. Data collection was acquired retrospectively with neurologic compromise between 2012 and 2017 in patients between 0 to 18 years old, with neurological impairment and Nissen fundoplication. 35 patients were included. Median age was 55 months (2-190). Gastroesophageal reflux disease was diagnosed in the 48%, in the 52% of this the diagnosis was clinical. It was performed by laparoscopic technique in the 91.4% of the cases gastrostomy was done in the same surgical time in 86% of the patients because of neurological impairment and risk of aspiration. In 25.7% (n = 9) there were functional and motor complications, Dumping syndrome (5.5%) accommodation disorders (11.4%) and recurrence of reflux (11.4%). Redo Nissen was required in the 8.5% of the patients (n = 3). In 75% of the patients with complications, gastrostomy was performed in the same surgical time. It could not be demonstrated that gastrostomy at the time of antireflux surgery was associated with greater frequency of complications.


2020 ◽  
Vol 9 (3) ◽  
pp. 169-179
Author(s):  
Bunga Fauza Fitri Ajjah ◽  
Teuku Mamfaluti ◽  
Teuku Romi Imansyah Putra

Latar Belakang : Gastroesophageal Reflux Disease (GERD) merupakan penyakit kronik yang terjadi pada masyarakat dewasa terutama mahasiswa. Faktor yang dapat menyebabkan GERD adalah pola makan termasuk jenis-jenis makanan tertentu yang dikonsumsi, frekuensi makan, dan ketidakteraturan makan. Mahasiswa kedokteran selalu berada di bawah tekanan akademik sehingga muncul ketidaknyamanan pencernaan yang memberi dampak bagi kualitas hidup dan aktivitas sehari-hari. Tujuan : Mengetahui hubungan pola makan dengan terjadinya Gastroesophageal Reflux Disease (GERD) pada mahasiswa Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Syiah Kuala. Metode : Penelitian ini merupakan penelitian deskriptif analitik observasional dengan desain cross sectional. Teknik pengambilan sampel yang digunakan adalah stratified random sampling sebanyak 216 subjek yang memenuhi kriteria inklusi. Pengumpulan data diperoleh dari hasil pengisian kuesioner oleh subjek menggunakan kuesioner pola makan yang sudah divalidasi dan dimodifikasi oleh peneliti dan menggunakan Gastroesophageal Reflux Disease Questionnaire (GERDQ) dalam bahasa Indonesia yang telah valid. Kuesioner pola makan dinilai dari segi keteraturan makan, frekuensi makan, jenis-jenis makanan, dan porsi makanan yang dikonsumsi. Hasil : Subjek yang memiliki pola makan buruk dan mengalami GERD sebanyak 34,2% sedangkan subjek yang memiliki pola makan baik dan tidak mengalami GERD sebanyak 86,5%. Analisis data dilakukan dengan menggunakan uji Chi Square. Hasil analisis data menunjukkan terdapat hubungan antara pola makan dengan terjadinya Gastroesophageal Reflux Disease (GERD) (p = 0,004).Simpulan : Terdapat hubungan antara pola makan dengan terjadinya Gastroesophageal Reflux Disease (GERD) pada mahasiswa Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Syiah Kuala.


2016 ◽  
Vol 53 (3) ◽  
pp. 130-135 ◽  
Author(s):  
Seyed Mohsen DEHGHANI ◽  
Seyed Alireza TAGHAVI ◽  
Hazhir JAVAHERIZADEH ◽  
Maryam NASRI

ABSTRACT Background - Gastroesophageal reflux disease is the most common esophageal disorder in pediatrics. Objective - The aim of this study was to compare reflux parameters of typical and atypical symptoms of gastroesophageal reflux disease using 24-hour esophageal pH monitoring and multichannel intraluminal impedance in pediatric population. Methods - In this prospective study, 43 patients aged less than 18 year with suspected gastroesophageal reflux disease were enrolled. The patients were divided into two groups based on the main presenting symptoms (typical versus atypical). Twenty four-hour pH monitoring and multichannel intraluminal impedance were performed in all the patients for comparing these two group regarding association of symptoms and reflux. Number of refluxes, pH related reflux, total reflux time, reflux more than 5 minutes, longest time of the reflux, lowest pH at reflux, reflux index were recorded and compared. Data comparison was done using SPSS. Results - The mean age of the patients was 5.7±3.4 years and 65.1% were male. Out of 43 patients 24 cases had typical symptoms and 19 had atypical symptoms. The mean reflux events detected by multichannel intraluminal impedance was more than mean reflux events detected by pH monitoring (308.4±115.8 vs 69.7±66.6) with P value of 0.037, which is statistically significant. The mean symptom index and symptom association probability were 35.01% ± 20.78% and 86.42% ± 25.79%, respectively in multichannel intraluminal impedance versus 12.73% ± 12.48% and 45.16% ± 42.29% in pH monitoring (P value <0.001). Number of acid reflux was 46.26±47.16 and 30.9±22.09 for atypical and typical symptoms respectively. The mean symptom index was 18.12% ± 13.101% and 8.30% ± 10.301% in atypical and typical symptoms respectively (P=0.034). Bolus clearance was longer in atypical symptoms compared typical symptoms(P<0.05). Conclusion - Symptom index was significantly higher in atypical symptoms compared to typical symptoms. Higher number of acid reflux was found in children with atypical symptoms of reflux. Longer duration of bolus clearance was found in group with atypical symptoms of reflux.


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