scholarly journals A study on non-malignant lesion of larynx

2018 ◽  
Vol 4 (3) ◽  
pp. 655
Author(s):  
Bharathi Mohan Mathan M. ◽  
Selvam D. K. ◽  
Vikram V. J.
Keyword(s):  
Malignant Lesion ◽  
Voice Rehabilitation ◽  
Excision Biopsy ◽  
Common Symptom ◽  
Age Group ◽  
Laryngeal Diseases ◽  
Predominant Symptom ◽  
Laryngeal Lesions ◽  
Malignant Lesions ◽  
Benign Laryngeal Lesions

<p class="abstract"><strong>Background:</strong> Benign laryngeal lesions are a spectrum of laryngeal diseases where symptoms vary from discomfort in throat, pain in throat, change of voice to stridor. Prompt diagnosis and intervention will reverse the conditions in certain laryngeal lesions.</p><p class="abstract"><strong>Methods:</strong> A prospective study was carried out in department of ENT, Madras Medical College/Institute of Child Health, Chennai between August 2013-November 2015 of non-malignant lesions of larynx. All these cases underwent a thorough ENT examination, examined under direct laryngoscope or micro laryngeal examination as the situation warrants. Benign non –neoplastic lesions are usually treated by excision biopsy and the biopsy results were confirmed.  </p><p class="abstract"><strong>Results:</strong> This study included 50 cases of non-malignant lesions of larynx. In our study 34% of the cases fall in the age group of 20-30 years, followed by 22% in age group of 0-10 years. The mean age group was 26 years. Males were 72% and female constituted 28%. The hoarseness is the common symptom in 36 patients, while stridor was the predominant symptom in 14 patients. The treatment modality followed were micro laryngeal excision in 40 cases, tracheostomy in 6 cases.</p><p class="abstract"><strong>Conclusions:</strong> Management of the non-malignant lesions of larynx<strong>, </strong>by early diagnosis with effective conservative management in the initial stages, will reduce the necessity of the surgery. Counselling, voice rehabilitation, micro laryngeal surgery is the best modality.</p>

scholarly journals Rehabilitation of patients with benign vocal fold lesions

2009 ◽  
Vol 8 (3) ◽  
pp. 79-84
Author(s):  
O. V. Kotyanina
Keyword(s):  
Vocal Fold ◽  
Combined Therapy ◽  
Fundamental Principle ◽  
Voice Rehabilitation ◽  
Benign Vocal Fold Lesions ◽  
Laryngeal Lesions ◽  
Benign Laryngeal Lesions

Benign vocal fold lesions is the largest group of larynx diseases. At the present time the fundamental principle in treatment of benign laryngeal lesions is the combined therapy including surgical, medical and phonopedic methods of voice rehabilitation by indications.

scholarly journals Benign and malignant lesions of the breast: clinico-pathological perspective from a government teaching hospital in West Bengal, India

2018 ◽  
Vol 5 (11) ◽  
pp. 3460 ◽  
Author(s):  
Saurav Sarkar ◽  
Arista Lahiri ◽  
Soumyajyoti Bandyopadhyay ◽  
Snehasish Das ◽  
Tamal Chakraborty
Keyword(s):  
Ductal Carcinoma ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Benign Disease ◽  
Breast Diseases ◽  
P Value ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Peau D’Orange ◽  
Malignant Lesions

Background: While breast cancer is one of the most commonly diagnosed cancer more than half of the women develop some benign disease of breast in their lifetime. The current study was conducted to describe the clinico-pathological findings associated with breast diseases and study their relationship.Methods: A record-based cross-sectional study was conducted on the samples of breast tissue obtained by fine needle aspiration cytology (FNAC) examination. The clinical variables like age, sex, presenting complaint, involved side (right/left/both) etc. were taken from the clinical notes sent, and nature of the aspirate, histopathological diagnosis, nature of the diagnosed disease (benign/malignant), and axillary metastasis were taken as variables from pathological examination.Results: The mean age of the patients was 33.49 years (±13.24 years) with majority belonging to 20-40 years. Among the 184 specimens examined, 94.57% belonged to female patients. The most frequent presentation was with lump (95.11%). Complaint arising out of right breast (47.83%) were higher compared to left breast (40.76%). Involvement of the supero-lateral quadrant was seen in 75.54%. In 30.44% of the cases the material was bloody or blood-mixed. Majority of the patients (86.41%) were diagnosed with benign disease commonest being fibroadenoma. Ductal carcinoma was the commonest malignant lesion. Younger age group, absence of bloody discharge and absence of peau d’orange were associated with benign lesion in a statistically significant way (p-value <0.001).Conclusions: In consonance with published literature the findings suggest association of older age group with malignant lesions. Blood-mixed aspirate, peau d’orange appear to be danger signs.

scholarly journals Manual versus Automatic Classification of Laryngeal Lesions based on Vascular Patterns in CE+NBI Images

2020 ◽  
Vol 6 (3) ◽  
pp. 70-73
Author(s):  
Nazila Esmaeili ◽  
Alfredo Illanes ◽  
Axel Boese ◽  
Nikolaos Davaris ◽  
Christoph Arens ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Automatic Classification ◽  
Vascular Pattern ◽  
Objective Interpretation ◽  
Laryngeal Lesions ◽  
Malignant Lesions ◽  
Manual Classification

AbstractLongitudinal and perpendicular changes in the blood vessels of the vocal fold have been related to the advancement from benign to malignant laryngeal cancer stages. The combination of Contact Endoscopy (CE) and Narrow Band Imaging (NBI) provides intraoperative realtime visualization of vascular pattern in Larynx. The evaluation of these vascular patterns in CE+NBI images is a subjective process leading to differentiation difficulty and subjectivity between benign and malignant lesions. The main objective of this work is to compare multi-observer classification versus automatic classification of laryngeal lesions. Six clinicians visually classified CE+NBI images into benign and malignant lesions. For the automatic classification of CE+NBI images, we used an algorithm based on characterizing the level of the vessel’s disorder. The results of the manual classification showed that there is no objective interpretation, leading to difficulties to visually distinguish between benign and malignant lesions. The results of the automatic classification of CE+NBI images on the other hand showed the capability of the algorithm to solve these issues. Based on the observed results we believe that, the automatic approach could be a valuable tool to assist clinicians to classifying laryngeal lesions.

scholarly journals A Clinicopathologic and Epidemiologic Study of Chronic White Lesions in the Oral Mucosa

2017 ◽  
Vol 96 (8) ◽  
pp. E13-E17
Author(s):  
Sampurna Ghosh ◽  
Sudipta Pal ◽  
Soumya Ghatak ◽  
Somnath Saha ◽  
Surajit Biswas ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Epidemiologic Study ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Premalignant Lesions ◽  
Excision Biopsy ◽  
Severe Dysplasia ◽  
Cross Sectional ◽  
Malignant Lesions ◽  
Tobacco Chewing

Invasive oral squamous cell carcinoma is often preceded by the presence of clinically identifiable premalignant changes of the oral mucosa, including white lesions. We conducted a cross-sectional, observational study to assess the clinicopathologic and epidemiologic aspects of chronic oral mucosal white lesions to determine the necessity of early biopsy in these cases. Our study population was made up of 77 patients—50 males and 27 females, aged 15 to 70 years (mean: 42.9)—who presented with white lesions persisting for at least 4 weeks. All but 3 patients underwent a biopsy; the 3 exceptions were diagnosed with smear-proven candidiasis. Patients with moderate or severe dysplasia underwent an excision biopsy. The buccal mucosa was the single most common site of white lesions, occurring in 15 patients (19.5%), although 21 patients (27.3%) exhibited a diffuse involvement of the oral mucosa. Of the 77 patients, 59 (76.6%) had concerning findings: premalignant lesions in 45 patients (58.4%) and malignant lesions in 14 (18.2%). Also, dysplasia was seen in 8 patients (10.4%), all of whom had premalignant lesions. Tobacco chewing (p = 0.008) and betel quid chewing (p = 0.029) were significantly associated with the development of premalignant and malignant lesions; a longer duration of tobacco chewing (≥10 yr) was significantly associated with a higher risk of malignant but not premalignant lesions (p = 0.031). Finally, illiteracy was a significant risk factor for premalignant and malignant lesions (p = 0.03). Our findings support the necessity of biopsy in every case. Early detection of oral carcinoma by biopsy of all oral white lesions would not only prevent patients from undergoing disfiguring surgery and chemoradiation, but it also would increase the 5-year survival rate.

Sclerosing Angiomatoid Nodular Transformation of the Spleen

2013 ◽  
Vol 137 (9) ◽  
pp. 1309-1312 ◽  
Author(s):  
Dinesh Pradhan ◽  
Sambit K. Mohanty
Keyword(s):  
Current Knowledge ◽  
Benign Lesion ◽  
Good Prognosis ◽  
Unknown Etiology ◽  
Age Group ◽  
Imaging Findings ◽  
Effective Technique ◽  
Sclerosing Angiomatoid Nodular Transformation ◽  
Malignant Lesions ◽  
Mitotic Figures

Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen is a rare benign lesion of the spleen with unknown etiology. SANT is classically considered to be a female-predominant disease, with most of the patients in the 30- to 60-year age group. Most lesions are found incidentally on imaging. Although SANT has specific imaging findings, the differential diagnosis from other splenic tumors or malignant lesions is very difficult. Histopathologically, these tumors reveal multiple confluent angiomatoid nodules; these nodules are surrounded by concentric collagen fibers exhibiting an inflammatory and myofibroblastic response and are accompanied by numerous erythrocytes and siderophages. The nodules are populated by endothelial cells, phenotypically recapitulating normal splenic vasculature, such as sinusoids, capillaries, and small veins. Nuclear atypia is minimal, mitotic figures are extremely rare, and necrosis is consistently absent. This lesion has a unique immunohistochemical profile characterized by CD34−CD31+CD8+ sinusoids, CD34+CD31+CD8− capillaries, and CD34−CD31+CD8− small veins. CD68 is positive in macrophages. Splenectomy is a useful and effective technique for the management of SANT. SANT patients have a good prognosis, with no recurrence after splenectomy. In this review, we discuss the current knowledge of SANT of the spleen and its clinical relevance.

Benign Laryngeal Lesions

2022 ◽  
Author(s):  
Jeffrey Straub ◽  
Brandon Kim
Keyword(s):  
Laser Therapy ◽  
Vocal Fold ◽  
Clinical Presentation ◽  
Benign Tumors ◽  
Vocal Hygiene ◽  
Laryngeal Lesions ◽  
Benign Laryngeal Lesions ◽  
Vocal Fold Nodules

Benign laryngeal lesions represent a diverse set of pathologies whose clinical presentation may range from no symptoms to dyspnea and/or dysphonia. Flexible fiberoptic laryngoscopy and videolaryngostroboscopy are important in distinguishingdifferent types of lesions, and management and treatment are dependent on the identification of these lesions, as they have different etiologies. Some lesions such as vocal fold nodules and polyps are primarily phonotraumatic and may benefit fromspeech therapy and vocal hygiene as initial approaches. Vocal fold cysts and benign tumors may benefit from microlaryngeal approaches, while capillary ectasias, polypoid corditis, laryngoceles, saccular cysts, and papilloma may benefit from laser therapy. Vocal fold granulomas may arise from various etiologies such as intubation, traumatic behaviors, or reflux. Polypoid corditis arises from smoking. This review is intended to provide an overview of the variety of lesions that encompass non-malignant laryngeal lesions that is both suitable for junior and senior residents. This review contains 12 figures, 5 tables, and 64 references Keywords: Benign laryngeal lesions, Laryngocele, Polyp, Cyst, Polypoid Corditis, Papilloma

scholarly journals Clinical study of ectopic pregnancy

2017 ◽  
Vol 6 (8) ◽  
pp. 3498
Author(s):  
Meenakshi T. Chate ◽  
Bhagyashree Chate ◽  
Kranti Chate
Keyword(s):  
Ectopic Pregnancy ◽  
Clinical Presentation ◽  
Public Health Issue ◽  
Common Symptom ◽  
Age Group ◽  
Common Site ◽  
Common Risk Factor ◽  
Medical College ◽  
Endometrial Cavity ◽  
Rising Incidence

Background: Ectopic pregnancy is pregnancy that develops following implantation anywhere other than the endometrial cavity of uterus. Objective of present study was to investigate the risk factors, clinical presentation and sites of ectopic pregnancy along with management and assessment of risk of maternal mortality and morbidity.Methods: The study was undertaken at Dr. Shankar Rao Chavhan Government Medical College and Guru Govind singhji hospital, Nanded between December 2012 and May 2014 after obtaining clearance from the Hospital Ethical Committee.Results: Maximum incidence of tubal gestation occurred between the age group of 21-25 years. Greater incidence was noted in multiparous woman. Tubectomy was the most common risk factor seen in 23.65% cases. The most common symptom observed is abdominal pain seen in 92.47% cases. The most common site of ectopic was ampulla seen in 51.61% cases. The most common mode of presentation was rupture seen in 71 cases about 76.35% cases. Unilateral salpingectomy was done in 70 cases about 75.26% cases.Conclusions: Since ectopic pregnancy remains a gynecological catastrophe in countries and a major challenge to the reproductive performance of women worldwide, it should be considered a relevant public health issue. With its rising incidence, which is likely to continue increasing because of the various factors discussed, it is necessary to devise means of early detection and treatment.

scholarly journals Complex fibroadenoma with focal ossification- an enigmatic finding in a less common tumor

2021 ◽  
Vol 8 (5) ◽  
pp. 1650
Author(s):  
Subhransu Kumar Hota ◽  
Ranjana Giri ◽  
Hardik Kabra ◽  
Devika Chauhan ◽  
Prita Pradhan ◽  
...  
Keyword(s):  
Excision Biopsy ◽  
Radiological Findings ◽  
Breast Lump ◽  
In Situ Carcinoma ◽  
Unusual Occurrence ◽  
Malignant Lesions ◽  
Breast Lumps ◽  
Sclerosing Adenosis

Breast lumps have diverse causes including benign as well as malignant lesions. Fibroadenoma (FA) is a common cause of breast lump. Complex fibroadenomas, a particular subtype, pose diagnostic dilemmas due to confusing the radiological findings and hold higher incidence of transformation to malignancy. A 49 year old female presented with a painless lump in right breast for 2 years which appeared calcified on radiology. Excision biopsy was performed which grossly revealed an encapsulated grey-white firm to hard with cystic areas. Microscopically the sections showed a well encapsulated fibroepithelial tumor showing areas of sclerosing adenosis, hyalinization, cysts lined by cuboidal cells with eosinophilic secretions, areas of calcification and ossification. No evidence of lobular hyperplasia or in-situ carcinoma was seen. Patient was advised follow up. This case represents the unusual occurrence of complex fibroadenoma in a middle-aged female showing with ossification.

scholarly journals Nasomaxillary swellings: our experience at tertiary care hospital

2021 ◽  
Vol 7 (3) ◽  
pp. 469
Author(s):  
Mukesh Rawat ◽  
Archana Lall ◽  
Kavita Sachdeva
Keyword(s):  
Tertiary Care Hospital ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Final Diagnosis ◽  
Inverted Papilloma ◽  
Nasal Endoscopy ◽  
Common Symptom ◽  
Fungal Sinusitis ◽  
Care Hospital ◽  
Malignant Lesions

<p class="abstract"><strong>Background:  </strong>A wide spectrum of lesions may present as nasomaxillary swellings ranges from benign to malignant lesions including fungal sinusitis and fibro vascular lesions example: JNA (Juvenile nasopharyngeal angiofibroma) and Inverted papilloma. Many Pathologies ranging from benign to malignant tumors may mimic a simple Nasomaxillary mass. It is diagnostic challenge to determine pathology behind it. A detailed clinical evaluation with nasal endoscopy and relevant pre-operative investigations including radiological imaging and histopathological examination is essential to reach up to final diagnosis. The aim of the study was to do clinicopathological evaluation of patients presenting with nasomaxillary swelling and correlation of clinical, radiological and Histopathological findings.</p><p class="abstract"><strong>Methods: </strong>This was a prospective observational study on 50 nasomaxillary swelling patients who are presented in the Department of ENT and Head and Neck Surgery of N.S.C.B. MCH Jabalpur, a tertiary care Hospital, between March 2018 to August 2019. A detailed history taking and clinical examination with nasal endoscopy and relevant preoperative investigations including CECT Nose and PNS and histopathological examination was done in all patients.</p><p class="abstract"><strong>Results: </strong>50 Nasomaxillary swelling patients were selected for this study. 30 patients were male and 20 were females. Ages of patients were varied from 12 years to 72 years. 23 patients (46%) were malignant and 27 (54%) were benign. Histopathological examination results shows benign lesions like JNA (6 cases), fungal sinusitis (6 cases), dermoid cyst (1 case), inverted papilloma (3 cases), sebaceous cyst (1 case), jaw lesions (10 cases), (odontogenic like radicular/ infected cyst, dentigerous cyst, cystic ameloblastoma and non-odontogenic like fibrous dysplasia) and malignant lesions like SCC (squamous cell carcinoma) (12 cases), spindle cell sarcoma (2 cases), undifferentiated carcinoma (3 cases), adenocarcinoma (3 cases), adenoid cystic carcinoma (1 case), Invasive pleomorphic sarcoma (1 case) and malignant melanoma (1 case). SCC was most common lesion f/b JNA and fungal sinusitis. Well differentiated SCC was most common histological type (10 out of 12 cases of SCC). Most common symptom was nasal obstruction (66% cases) f/b epistaxis (52% cases) but epitasis was most common symptom among malignant and JNA cases. In 6 cases (3 JNA, 1 inverted papilloma, 1 malignancy and 1 radicular cyst) radiological diagnosis were not correlated with histological findings.</p><p class="abstract"><strong>Conclusions: </strong>Most our cases were malignant nasomaxillary lesions followed by fungal sinusitis and JNA. Most patients presented in advanced stage of disease so rapidly evaluation including nasal endoscopy should be done. CECT scan is essential to determine tumors extent and bony lesions. All patients should undergo hisotopatholigical examination. The final diagnosis should be made on the basis of clinical, radiological and histopathological findings.</p>

scholarly journals A Study of Management of Benign Lesions of the Larynx

2011 ◽  
Vol 1 (2) ◽  
pp. 61-64 ◽  
Author(s):  
Pankaj Kumar Doloi ◽  
Swagata Khanna
Keyword(s):  
Cost Effective ◽  
Clinical Findings ◽  
Benign Tumors ◽  
Complete Relief ◽  
Vocal Rehabilitation ◽  
Body Sensation ◽  
Laryngeal Lesions ◽  
Endolaryngeal Surgery ◽  
Microlaryngeal Surgery ◽  
Benign Laryngeal Lesions

ABSTRACT A two-year prospective study was conducted from June 2008 to May 2010. A total of 80 patients with benign laryngeal lesions were included in the study based on symptoms, such as hoarseness of voice, foreign body sensation, vocal fatigue, dyspnea and cough and with positive clinical findings on indirect laryngoscopy. Diagnostic and therapeutic laryngoscopic and microlarygoscopic procedures were employed. Vocal cord polyps were observed to be the commonest type of lesions. Out of the 80 patients in the study group, 40% patients got complete relief with voice rest and vocal rehabilitation; 60% patients required surgery, which included endoscopic/microlarygoscopic endolaryngeal surgery and external approaches. There was no recurrence in cases of vocal polyps and nodules during the period of observation. Endolaryngeal surgery and voice rest offer a cost-effective, useful and safe method for the management of benign laryngeal lesions. With the inclusion of lasers, they can be more precisely operated. As such, the standard treatment of choice in all types of benign tumors of the larynx should consist of a triad of approach by microlaryngeal surgery (either microscopic or endoscopic, with or without use of lasers), voice rest and vocal rehabilitation.

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