scholarly journals Prevalence of osteoporosis in India: an observation of 31238 adults

2021 ◽  
Vol 7 (2) ◽  
pp. 362
Author(s):  
Sushrut Babhulkar ◽  
Shobhit Seth
Keyword(s):  
Bone Loss ◽  
Postmenopausal Women ◽  
The Elderly ◽  
Study Data ◽  
Mineral Density ◽  
T Score ◽  
Calcaneal Quantitative Ultrasound ◽  
Total Data ◽  
Osteoporosis Prevalence ◽  
Prevalence Of Osteoporosis

<p><strong>Background</strong>: Aim of the study was to determine the prevalence of bone loss (both osteopenia and osteoporosis) at national and regional levels in India.</p><p><strong>Methods</strong>: In this retrospective study, data obtained from in-clinic screening camps conducted for bone loss was analysed. Participants were apparently healthy adults (aged 18 years and above) evaluated for bone mineral density (BMD) using calcaneal quantitative ultrasound (QUS) of left foot. Based on t score of BMD obtained, participants were labelled as normal (T-score &lt;-1 SD), osteopenia (t score-1 to -2.5 SD) and osteoporosis (t score &lt;-2.5 SD).</p><p><strong>Results</strong>: In total, data of 31238 participants was analysed retrospectively. Mean age was 47.8±14.2 years and 47.6% were females. Among females, 38.8% were postmenopausal women (age &gt;50 years). Overall prevalence of osteopenia and osteoporosis was 49.9 and 18.3% respectively. Across East, West, North and South India, the prevalence of osteopenia was 51.3, 47.9, 55.6 and 47.4% respectively whereas prevalence of osteoporosis was 18.4, 16.3, 16.4 and 20.7% respectively. Prevalence of osteoporosis was slightly higher in females than males (19.4 vs 17.3%). Among postmenopausal women, overall osteoporosis prevalence was 33.1% and ranged from 16.9% in North region to 21.8% South region. Prevalence of osteoporosis (37.0 vs 12.5%) was higher in elderly (≥60 years) than adults (&lt;60 years).</p><p><strong>Conclusions</strong>: Among adults, nearly one out of two have osteopenia and one out of five have osteoporosis. Osteoporosis prevalence was higher in the women and in the elderly. Nearly one out of three women in postmenopausal age group have osteoporosis. There is no substantial difference across the four regions of the country. Considering the significant prevalence of low BMD, there is need to increase the awareness about bone health in general population.</p><p> </p><p> </p>

scholarly journals Association between Bone Mineral Density and Hypertension in Postmenopausal Women

2021 ◽  
Vol 3 (4) ◽  
pp. 116-120
Author(s):  
S. M. Muraduzzaman ◽  
S. Begum ◽  
S. Ali ◽  
S. Sultana ◽  
M. Saiedullah ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Femoral Neck ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
The Elderly ◽  
Inverse Association ◽  
Mineral Density ◽  
T Score ◽  
Confounding Variables

Background: Low bone mineral density (BMD) is a common disorder in the elderly and found to be most prevalent in postmenopausal women which are thought to be associated with several factors including hypertension, however, results are inconsistent in different studies. Aim of the study: This study aimed to explore the association between BMD and hypertension in postmenopausal women. Methods and materials: In this study, total 76 postmenopausal women were included. BMD was determined at the lumbar spine and femoral neck by dual-energy x-ray absorptiometry (DEXA). Anthropometric data and status of hypertension and diabetes were collected according to a pre-structured questioner. Results: Age (mean±SD) of the postmenopausal women was 57±9 years. Among them, 46 (60.5%) subjects were hypertensive and 30 (39.5%) were normotensive. Bone mineral density (g/cm2) in normotensive women and in hypertensive women were 0.79±0.15 vs 0.74±0.15 (p=0.160) at lumbar spine; 0.70±0.12 vs 0.69±0.13 (p=0.271) at right femoral neck and 0.73±0.15 vs 0.71±0.13 (p=0.592), respectively. T-scores at lumbar spine, right and left femoral neck in normotensive and hypertensive postmenopausal women were -2.28±1.37 vs -2.75±1.35 (p=0.153), -1.70±1.16 vs -1.95±1.07 (p=0.363) and -1.82±0.95 vs -1.93±1.01 (p=0.632) respectively. On multiple regression analysis, BMD and T-score only at lumbar spine showed inverse association with hypertension (β=-0.069, p=0.045; β=-0.612, p=0.050) on adjusting confounding variables. Conclusion: Hypertension is independently associated with BMD and T-score measured from the lumbar spine but not with BMD and T-score measured from the femoral neck in postmenopausal women.

scholarly journals BMD status of Postmenopausal Women in relation with BMI: A study with 93 cases

2016 ◽  
Vol 17 (2) ◽  
pp. 138-141
Author(s):  
Samira Sharmin ◽  
Mabubul Haque ◽  
Syedur Rahman Miah ◽  
Md Mahbub Ur Rahman ◽  
Jasmine Ara Haque ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Femoral Neck ◽  
Postmenopausal Women ◽  
Lumbar Vertebrae ◽  
The Body ◽  
Mineral Density ◽  
Cross Sectional ◽  
T Score ◽  
Minimal Trauma ◽  
The Mean

Objectives: Low bone mass is a common disorder in elderly population which predisposes to fracture with minimal trauma. This study was performed to find out the association between the Body Mass Index (BMI) and Bone Mineral Density (BMD) in postmenopausal women.Materials and Methods: This cross sectional study was carried out at Institute of Nuclear Medicine and Allied Sciences Comilla and Mitford, Dhaka over a period of 12 months from January 2013 to December 2013. A total 93 postmenopausal women were enrolled for this study. All postmenopausal women underwent a BMD scan of femoral neck and lumbar vertebrae using a Dual Energy X-ray Absorptiometry (DEXA). Participants were categorized into three groups according to their age and BMI. BMD were expressed base on T-score according to WHO criteria. The relation among BMI, age and BMD were assessed.Results: The results of this study showed that the mean age of the study group was 57.13±7.49 years with range of 46 to 75 years. The most postmenopausal women were in age group 55-65years. The mean BMI of the study subjects were 24.18±5.08 kg/m2 with a range of 15.62 to 36.20 kg/m2. Among 93 subjects osteopenia was greater at lumbar spine (45.2%) with T-score mean±SD-1.83±0.33 and osteoporosis at femoral neck (51.6%) with T-score mean ±SD-3.36±-0.67. Pearson’s correlation coefficient test showed inverse relationship between age and BMD both lumbar spine (r = -0.301, p = 0.003) and femoral neck (r = -0.303, p=0.003) whereas the positive relation between BMI and BMD both at lumbar spine (r=0.338, p=0.001) and femoral neck (r =0.343, p=0.001). These showed that with advancing age, BMD decreases and the risk of osteoporosis increases and with increasing BMI, BMD increases and risk of osteoporosis decreases.Conclusion: The findings of this study portrait that aging and low BMI are risk factors associated with bone loss. So preventive measure should be taken for high risk post menopausal women.Bangladesh J. Nuclear Med. 17(2): 138-141, July 2014

scholarly journals Study of prevalence of osteoporosis in males of above 40 years age group attending SMS Hospital, Jaipur

2017 ◽  
Vol 3 (4) ◽  
pp. 837
Author(s):  
Parwez Qureshi ◽  
R. C. Meena ◽  
Jakir Husain ◽  
Gaurav Deshwar ◽  
Vineet Maheshwari ◽  
...  
Keyword(s):  
Vitamin D ◽  
Dietary Habits ◽  
Good Control ◽  
Age Group ◽  
Mineral Density ◽  
Cross Sectional ◽  
T Score ◽  
Vitamin D Levels ◽  
Study Population ◽  
Prevalence Of Osteoporosis

<p class="abstract"><strong>Background:</strong> Whenever osteoporosis is discussed, the focus is on women; men are far less likely to receive a diagnosis of osteoporosis or osteoporotic fracture because of considerable gaps in knowledge on male osteoporosis. The aim and objectives were to study the prevalence of osteoporosis in males of above 40 year age group attending SMS Hospital Jaipur &amp; to explore the influence of various modifiable and non-modifiable risk factors on BMD.</p><p class="abstract"><strong>Methods:</strong> Study Location: SMS Medical College and Hospital, Jaipur. Study design: Hospital based cross sectional study. Study period: April 2015 to December 2016. Sample Size: 200. Work up: After taking ethical clearance and informed verbal consent, demographic and clinical details were noted along with S- calcium, Vitamin D and bone mineral density assessment. Osteoporosis was defined as T score ≤−2.5 bone mass −1 to −2.5 and normal as &gt;−1. Data thus collected was analysed with help of SPSS 22.0 through frequency, percentages, Mean, SD and ANOVA.<strong></strong></p><p class="abstract"><strong>Results:</strong> Prevalence of osteopenia and osteoporosis in the study population was 28.5% and 11.5%. Age wise maximum prevalence was in the age group 71-80 years (31.81%). Prevalence of osteoporosis was more among Muslim community 20.83%, more in low socio economic group (BPL). T score of study population was -0.3705±1.41. The mean BMI, S-Calcium, Vitamin D levels and T score values among osteopenic and osteoporotic patients were statistically highly significant when compared to patients without osteo-penic/porotic changes (p&lt;0.05).</p><p><strong>Conclusions:</strong> Osteoporosis is a silent killer and prevention is better than cure as prevention requires simple steps such as good dietary habits, active life style, good control of systemic disorders, reduced intake of tobacco and alcohol.</p>

scholarly journals Prevalence of osteoporosis and osteoporotic fractures in postmenopausal women with type 2 diabetes mellitus

2021 ◽  
Vol 3 (3) ◽  
Author(s):  
Lamia Oulkadi ◽  
Bouchra Amine ◽  
Imane El binoune ◽  
Samira Rostom ◽  
Rachid Bahiri
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Postmenopausal Women ◽  
Mineral Density ◽  
Control Subjects ◽  
Increased Risk ◽  
Significant Difference ◽  
Prevalence Of Osteoporosis

Type 2 diabetes mellitus (T2DM) and osteoporosis are chronic diseases with increasing prevalence. The aim of this study was to determine the prevalence of osteoporosis and osteoporotic fracture in women with T2DM and to identify predictive factors of fracture occurrence. The prevalence of osteoporosis and fractures in postmenopausal women with T2DM was 23.1% and 16.9%, respectively. 46.2% of T2DM patients had normal bone mineral density (BMD) (P<0.01) and 58.5% of control subjects had osteopenia (P<0.01). Incidence of fracture in T2DM patients with osteopenia was significantly increased versus control subjects when stratified according the BMD (P=0.009). By stratifying T2DM patients according to fractures, factors that were significantly associated with occurrence included T2DM duration (P=0.038), use of insulin (P=0.017), and lower BMD (P=0.048). Our study suggests that there was a higher prevalence of fracture in T2DM patients compared to control subjects and a significant difference in BMD was found between the groups. We also showed that insulin use, low BMD, and long duration of T2DM are factors associated with an increased risk of bone fracture.

scholarly journals Pemberian Kalium Buah Pisang Lampung terhadap Densitas Mineral Tulang pada Lansia

2019 ◽  
Vol 5 (1) ◽  
pp. 30
Author(s):  
Edy Waliyo ◽  
Nopriantini Nopriantini ◽  
Shelly Festilia Agusanty
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Random Sampling ◽  
The Elderly ◽  
Control Group ◽  
Mineral Density ◽  
Control Group Design ◽  
Separate Sample ◽  
Group Design ◽  
T Score

Abstract: Effect of Lampung Banana Potassium on Bone Mineral Density in the Elderly. This study aims to determine the effect of banana lampung on bone mineral density in the elderly in the Social Welfare Tresna Werdha and Werdha Graha Kasih Father’s home). This research is a research with experimental design with the separate sample pretest posttest control group design. The research was carried out in the Tresna Werdha Social Institution and the Werdha Graha Kasih Father’s house, from May to July 2017. The sampling technique was taken by random sampling The result of potassium feeding on 150 grams of banana per day for 30 days by increasing BMD T-score of 0.17 while in control group (without banana lampung) BMD T-score decreased by - 0.32. After intervention in both groups showed a difference of BMD T-score of 0.49. Abstrak: Pemberian Kalium Buah Pisang Lampung terhadap Densitas Mineral Tulang pada Lansia. Penelitian ini bertujuan untuk mengetahui mengetahui pengaruh pemberian buah pisang lampung terhadap bone mineral density pada lansia di wilayah Panti Sosial Tresna Werdha dan panti Werdha Graha Kasih Bapa). Penelitian yang dilakukan ini adalah penelitian dengan desain eksperimen dengan rancangan the separate sample pretest posttest control group design. Penelitian dilaksanakan di wilayah Panti Sosial Tresna Werdha dan panti Werdha Graha Kasih Bapa), mulai bulan Mei s/d Juli 2017. Teknik sampling diambil dengan cara random sampling Hasil pemberian kalium pada buah pisang lampung sebanyak 150 gr setiap hari selama 30 hari dengan dapat meningkatkan BMD T-score sebesar 0,17 sedangkan pada kelompok control (tanpa pemberian buah pisang lampung) BMD T-score menurun sebesar - 0,32. Setelah intervensi pada ke dua kelompok menunjukkan adanya perbedaan BMD T-score sebesar 0,49.

scholarly journals TSH suppressive therapy and bone

2020 ◽  
Vol 9 (7) ◽  
pp. R158-R172 ◽  
Author(s):  
Alessandro Brancatella ◽  
Claudio Marcocci
Keyword(s):  
Bone Loss ◽  
Postmenopausal Women ◽  
Bone Cells ◽  
Trabecular Bone Score ◽  
Experimental Studies ◽  
Bone Architecture ◽  
Tsh Receptor ◽  
Suppressive Therapy ◽  
Mineral Density ◽  
Increased Risk

Thyroid hormones stimulate bone turnover in adults by increasing osteoclastic bone resorption. TSH suppressive therapy is usually applied in patients with differentiated thyroid cancer (DTC) to improve the disease outcome. Over the last decades several authors have closely monitored the potential harm suffered by the skeletal system. Several studies and meta-analyses have shown that chronic TSH suppressive therapy is safe in premenopausal women and men. Conversely, in postmenopausal women TSH suppressive therapy is associated with a decrease of bone mineral density, deterioration of bone architecture (quantitative CT, QCT; trabecular bone score, TBS), and, possibly, an increased risk of fractures. The TSH receptor is expressed in bone cells and the results of experimental studies in TSH receptor knockout mice and humans on whether low TSH levels, as opposed to solely high thyroid hormone levels, might contribute to bone loss in endogenous or exogenous thyrotoxicosis remain controversial. Recent guidelines on the use of TSH suppressive therapy in patients with DTC give value not only to its benefit on the outcome of the disease, but also to the risks associated with exogenous thyrotoxicosis, namely menopause, osteopenia or osteoporosis, age >60 years, and history of atrial fibrillation. Bone health (BMD and/or preferably TBS) should be evaluated in postmenopausal women under chronic TSH suppressive therapy or in those patients planning to be treated for several years. Antiresorptive therapy could also be considered in selected cases (increased risk of fracture or significant decline of BMD/TBS during therapy) to prevent bone loss.

scholarly journals Prevalence of osteoporosis in hysterectomised as compared to non-hysterectomized women in 7th decade of life

2018 ◽  
Vol 7 (5) ◽  
pp. 1974
Author(s):  
Saba Shamim ◽  
Manju Lal ◽  
Rana Shamim
Keyword(s):  
Postmenopausal Women ◽  
Bone Mineral ◽  
The Body ◽  
Public Health Issue ◽  
Mineral Density ◽  
Bone Mineral Loss ◽  
Age Related ◽  
Increased Risk ◽  
Prevalence Of Osteoporosis ◽  
Mineral Loss

Background: Osteoporosis is considered as a major public health issue with fragility fractures of the hip, vertebrae and distal radius being the most important consequences. It has been said to be an age-related degenerative process. However, postmenopausal women develop this disease due to age-related bone mineral loss as well as due to declining levels of estrogen in the body following menopause leading to increased risk of fractures. Objectives of this study were to find out the prevalence of osteoporosis in hysterectomised and non-hysterectomised postmenopausal women in 7th decade of life.Methods: Descriptive cross-sectional study done on a total of 66 postmenopausal women who were in their 7th decade of life. They were divided into two groups, one consisting of 36 women who underwent natural menopause and the other group of 30 women who had surgical menopause. The bone mineral density of both the groups was measured using DEXA scan and comparison was done between these study groups.Results: Out of 30 hysterectomised subjects, 24 (80%) were found to be having osteoporosis, 6 (20%) had osteopenia and none had normal BMD. While out of 36 subjects in the non-hysterectomised group, 14 (38.88%) had osteoporosis, 16 (44.44%) had osteopenia and 6 (16.66%) subjects had normal BMD. Significant relation (p-value 0.001) was found on comparison of the study groups. In addition, significant positive correlation was between BMD and BMI whereas negative correlation was seen between BMD and parity.Conclusions: Hysterectomy was found to increase the incidence of osteoporosis. Obesity was found to have protective effect against bone mineral loss while increasing parity had a negative relation with BMD.

scholarly journals The role of Tai Chi Chuan exercise on osteoporosis prevention and treatment in postmenopausal women

2011 ◽  
Vol 1 (1) ◽  
pp. 10
Author(s):  
Haiyan Chen
Keyword(s):  
Bone Loss ◽  
Postmenopausal Women ◽  
Tai Chi ◽  
Weight Bearing ◽  
Depression And Anxiety ◽  
Osteoporosis Prevention ◽  
Mineral Density ◽  
Cross Sectional ◽  
Tai Chi Chuan

Osteoporosis is a disease characterized by fragile bones and high susceptibility to low trauma fractures. Tai Chi, an ancient Chinese mind-body exercise that is reported to enhance muscle function, balance and flexibility, and to reduce pain, depression and anxiety, may safely and effectively be used to prevent or treat osteoporosis. The aim of this review is to evaluate the evidence for Tai Chi as an intervention to reduce rate of bone loss in postmenopausal women. A literature search on randomized controlled trials (RCTs), prospective cohort studies, and cross-sectional studies that included Tai Chi as an intervention, and had at least 1 outcome related to measurement of bone metabolism were identified in PubMed/Medline. Twenty-one controlled studies were identified in the database, which suggested Tai Chi slowed down the loss of bone mineral density in most postmenopausal women, improved balance and strength, relieves pain from arthritis, and improved mental strength so they can cope better with chronic diseases. Regular Tai Chi Chuan exercise is beneficial for retarding bone loss in the weight-bearing bones of postmenopausal women.

scholarly journals Relation between intima-media thickness and bone mineral density in postmenopausal women: a cross-sectional study

2011 ◽  
Vol 129 (3) ◽  
pp. 139-145 ◽  
Author(s):  
Daniela Fodor ◽  
Cosmina Bondor ◽  
Adriana Albu ◽  
Laura Muntean ◽  
Siao-pin Simon ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Femoral Neck ◽  
Postmenopausal Women ◽  
Atherosclerotic Plaque ◽  
Vertebral Fractures ◽  
Mineral Density ◽  
Cross Sectional ◽  
T Score ◽  
Osteoporotic Vertebral Fractures ◽  
The Relationship

CONTEXT AND OBJECTIVES: Controversy exists regarding the relationship between atherosclerosis and osteoporosis. The aim of this study was to determine the relationship between intima-media thickness (IMT) of the common carotid artery (CCA), presence of calcified atherosclerotic plaques and bone mineral density (BMD) evaluated by dual energy X-ray absorptiometry (DXA), in postmenopausal women. DESIGN AND SETTING: Cross-sectional study at Second Internal Medicine Clinic, Cluj-Napoca, Romania. METHODS: We studied the IMT (left and right CCA and mean IMT) and T-score (lumbar spine L2-L4, femoral neck and total hip) in 100 postmenopausal women (mean age 64.5 years). The presence of calcified atherosclerotic plaque and osteoporotic vertebral fractures was also noted. RESULTS: IMT in the left and right CCA and mean IMT were significantly associated with T-score measured for the lumbar spine L2-L4, femoral neck and total hip, with lower T-score, in the osteoporotic group than in the normal and osteopenic groups (P < 0.05). IMT had a significantly negative correlation with the lumbar spine T-score and femoral neck T-score; and mean IMT with lowest T-score. Mean IMT (P < 0.001), high blood pressure (P = 0.005) and osteoporotic vertebral fractures (P = 0.048) showed statistical significance regarding the likelihood of developing atherosclerotic plaque. CONCLUSIONS: In women referred for routine osteoporosis screening, the relationship between CCA, atherosclerosis and osteoporosis can be demonstrated using either cortical or trabecular BMD. Vertebral fractures may be considered to be a likelihood factor for atherosclerotic plaque development.

Zoledronic Acid Prevents Cancer Treatment–Induced Bone Loss in Premenopausal Women Receiving Adjuvant Endocrine Therapy for Hormone-Responsive Breast Cancer: A Report From the Austrian Breast and Colorectal Cancer Study Group

2007 ◽  
Vol 25 (7) ◽  
pp. 820-828 ◽  
Author(s):  
Michael F.X. Gnant ◽  
Brigitte Mlineritsch ◽  
Gero Luschin-Ebengreuth ◽  
Stephan Grampp ◽  
Helmut Kaessmann ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Zoledronic Acid ◽  
Bone Loss ◽  
Endocrine Therapy ◽  
Premenopausal Women ◽  
Adjuvant Endocrine Therapy ◽  
Phase Iii ◽  
Endocrine Treatment ◽  
Mineral Density ◽  
T Score

Purpose Adjuvant therapy for breast cancer can be associated with decreased bone mineral density (BMD) that may lead to skeletal morbidity. This study examined whether zoledronic acid can prevent bone loss associated with adjuvant endocrine therapy in premenopausal patients. Patients and Methods This study is a randomized, open-label, phase III, four-arm trial comparing tamoxifen (20 mg/d orally) and goserelin (3.6 mg every 28 days subcutaneously) ± zoledronic acid (4 mg intravenously every 6 months) versus anastrozole (1 mg/d orally) and goserelin ± zoledronic acid for 3 years in premenopausal women with hormone-responsive breast cancer. In a BMD subprotocol at three trial centers, patients underwent serial BMD measurements at 0, 6, 12, 24, and 36 months. Results Four hundred one patients were included in the BMD subprotocol. Endocrine treatment without zoledronic acid led to significant (P < .001) overall bone loss after 3 years of treatment (BMD, −14.4% after 36 months; mean T score reduction, −1.4). Overall bone loss was significantly more severe in patients receiving anastrozole/goserelin (BMD, −17.3%; mean T score reduction, −2.6) compared with patients receiving tamoxifen/goserelin (BMD, −11.6%; mean T score reduction, −1.1). In contrast, BMD remained stable in zoledronic acid–treated patients (P < .0001 compared with endocrine therapy alone). No interactions with age or other risk factors were noted. Conclusion Endocrine therapy caused significant bone loss that increased with treatment duration in premenopausal women with breast cancer. Zoledronic acid 4 mg every 6 months effectively inhibited bone loss. Regular BMD measurements and initiation of concomitant bisphosphonate therapy on evidence of bone loss should be considered for patients undergoing endocrine therapy.

Sign in / Sign up

Export Citation Format

Share Document