scholarly journals A clinical study of cutaneous manifestations in neonates at a tertiary health care center

Author(s):  
M. Sneha ◽  
Kumaravel Sadagopan ◽  
Vaishnavi D.

<p class="abstract"><strong>Background:</strong> Cutaneous alterations are commonly seen in neonates as a normal process of adaptation to the external air environment after birth. It is good to know about transient skin lesions in infants to distinguish them from other conditions that prevent unwanted neonate therapy. Parents should be confident of the excellent prognosis of these manifestations of the skin. The aim of the study was to determine the patterns of cutaneous manifestations occurring among the newborn.</p><p class="abstract"><strong>Methods:</strong> This prospective study was conducted in the newborn with at-least one cutaneous manifestation. A detailed history of the neonates and mother was collected using pre-designed proforma.<strong></strong></p><p class="abstract"><strong>Results:</strong> Of 100 neonates, 52 were males, 48 were females, of these, 85 were born at term, 10 were preterm, and 5 were post-term. Mongolian spot was seen in lumbosacral, buttocks and extremities in 80 (80%) neonates, vernix caseosa in 20 (20%) neonates. Milia in 14 (14%) neonates, eczematous eruption in 30 (12.5%).</p><p class="abstract"><strong>Conclusions:</strong> This neonatal skin research has provided details on normal variants occurs during the neonatal phase. It is necessary to know that most newborn skin lesions are temporary and do not require any treatment.</p>

Author(s):  
Pratik Kumar ◽  
Vijay Domple ◽  
Gautam Khakse

Rabies is a zoonotic disease that affects the central nervous system of mammals and has a high mortality rate. It is a viral disease that can be prevented by vaccination. Dogs are the leading cause of human rabies deaths, accounting for up to 99% of all human rabies transmissions. On 15th December 2019 an 8 years old male child was bitten by a stray dog outside of his house. The patient visited with his parents to a nearby primary health care center on same day where his wound was washed with water. He received first dose of anti-rabies vaccine and was referred to a tertiary care center for immunoglobulin because of a history of wound bleeding. They did not visit tertiary care center for immunoglobulin as advised. 15 days after exposure on 1st January 2021 the patient presented with unusual behavior like fear of water and tremor. On examination his pupils were found dilated and he was referred to isolation ward of tertiary care center. Based on the history of animal bites and clinical signs, the patient was diagnosed as probable case of rabies. The patient eventually died within 24 hours of admission. Such kind of incident shows that there is lack of awareness regarding rabies in community. In this case, if the patient had completed the anti-rabies vaccination schedule and visited a higher centre on time for immunoglobulin, death could have been avoided. Mortality due to rabies can be prevented by raising public awareness about immunization.


Author(s):  
Tushar Nagtode ◽  
Y. R. Lamture ◽  
Venktesh Rewale ◽  
P. Tanveer ◽  
Aditya Mundada

Background: Incidence of perforation on posterior wall of stomach is rare throughout world; its occurrence has not been found till now in literature of central India. diffuse symptoms with delayed presentation to health center and poorly skilled faculty with facilities make a way to raise in total number of deaths associated with posterior gastric perforation. Objective: To report a rare case of posterior gastric perforation at a tertiary health care center in Central India, which would be first to be documented. Case Presentation: A 74-year-old male patient was referred to Department of General Surgery, AVBRH, with chief complaint of acute abdominal pain for two days. He had a history of alcohol consumtion which was stopped 2 years back A moderately distended, distinctly tender abdomen accompanied by guarding, rigidity and excluded bowel sounds was unveiled by abdominal examination. Patient has been resuscitated with intravenous fluids, antibiotics and analgesics. Consequently, an emergency exploratory laparotomy revealed a significant collection of purulent peritoneal fluid, 1x1 cm sized perforation on posterior wall of stomach. Perforation was repaired and thus patient recovered in a satisfactory way. Conclusion: And since posterior gastric perforation is extremely uncommon and expected to worsen, associated with increased morbidity and mortality leading to missed presence, this case report indicates that evaluation of patients with gastric perforation, identify risk factors and ability to repair perforations right away along with resuscitation will greatly enhance clinical outcome.


2021 ◽  
Author(s):  
Daniela Marulanda Sandoval ◽  
Oscar Felipe Borja Montes ◽  
Jose Leonel Zambrano Urbano ◽  
Rigoberto Gomez Gutierrez

Abstract Mastocytosis is a group of rare diseases, which correspond to neoplasms of the myeloid lineage. In Colombia there are only case reports and so far there are no studies of greater extension. We conducted a case series in which an active search was made for patients with a diagnosis of mastocytosis, either cutaneous (CM) or systemic (SM), from the total number of consultations between June 2004 and June 2019 in the reference hemato-oncologic center ("mastocytosis"). A total of 4 cases of CM and 3 cases of SM were identified. The most frequent clinical manifestations were skin lesions, which were present in 100% of patients; of these hyperpigmented macules were the most frequent findings. Serum tryptase (TS) levels were found to be elevated in 67% (2/3) of patients with DM. Both TS levels and mean absolute eosinophils were higher in patients with MS. In this case series we found a higher frequency of extracutaneous involvement, and in general a very poor response to the management. The findings of this series are comparable to those reported in world literature.


Author(s):  
Shams Zia Usmani ◽  
Kshitij Saxena ◽  
Venkatarao Koti ◽  
Shrish Bhatnagar ◽  
Gaurav Paliwal ◽  
...  

<p class="abstract"><strong>Background:</strong> Cutaneous manifestations are common in neonates. Transient and pathological neonatal dermatoses should be differentiated to avoid unnecessary treatment and thus considering the variable nature and severity of neonatal skin lesions, it is important to be aware of the transient skin lesions in newborn and to differentiate these from other serious conditions which will avoid unnecessary therapy to the neonates and the parents can be assured of good prognosis of these skin manifestations. The present study has been carried out to study the clinical pattern of cutaneous lesion in neonatal period.</p><p class="abstract"><strong>Methods:</strong> A total of 255 neonates from Department of Dermatology in collaboration of Department of Pediatrics, Era’s Lucknow Medical College and Hospital were evaluated for cutaneous manifestations. A detailed assessment regarding history, clinical examination and investigations were recorded and analyzed.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 255 neonates, 138 (54.1%) were males and 117 (45.9%) were females. The sex ratio (M:F) was 1.18. The most common dermatoses were physiological desquamation (54.1%) and mongolian spots (37.6%) followed by milia (19.6%), miliaria (14%), epstein pearls (10.2%).</p><p class="abstract"><strong>Conclusions:</strong> The physiological and transient cutaneous lesions are common are in neonates. Physiological cutaneous manifestations were quite frequent apart from birthmarks/congenital cutaneous manifestations. An understanding of these manifestations helps in managing and deciding the appropriate manifestation.</p>


2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Farhana Tahseen Taj Sameer Haveri ◽  
Arun C. Inamadar

Background. Cutaneous alterations are common in neonates. The majority of lesions are physiological, transient, or self-limited and require no therapy. Although much has been reported on the various disorders peculiar to the skin of infant, very little is known about variations and activity of the skin in neonates. Objective. To study the various pattern of skin lesions in newborn and to estimate the prevalence of physiological and pathological skin lesions in newborn. Methods. A total of 1000 newborns were examined in a hospital-based, cross-sectional prospective study in the period of November 2007 to May 2009. Results. The physiological skin changes observed in order of frequency were sebaceous gland hyperplasia (89.4%), Epstein pearls (89.1%), Mongolian spot (84.7%), knuckle pigmentation (57.9%), linea nigra (44.5%), hypertrichosis (35.3%), miniature puberty (13.3%), acrocyanosis (30.9%), physiological scaling (10.8%), and vernix caseosa (7.7%). Of the transient noninfective conditions, erythema toxicum neonatorum was seen in 23.2% newborns and miliaria crystallina in 3% newborns. The birthmarks in descending order of frequency were salmon patch (20.7%), congenital melanocytic nevi (1.9%), and café-au-lait macule (1.3%). Cutaneous signs of spinal dysraphism were sacral dimple (12.8%), meningomyelocele (0.5%), acrochordons (0.1%), and dermoid cyst (0.1%). Conclusion. The physiological and transient skin lesions are common in newborns particularly sebaceous gland hyperplasia, Epstein pearls, Mongolian spots, and erythema toxicum neonatorum. It is important to differentiate them from other more serious skin conditions to avoid unnecessary therapeutic interventions.


Author(s):  
Abdullah Abualiat ◽  
Wifag Elobeid ◽  
Hala Edris

Tuberous sclerosis complex (TSC) is an inherited neurocutaneous disorder with multisystem involvement and highly variable expression of the disease. Common cutaneous manifestations include angiofibromas, periungual fibroma, ash-leaf-shaped macules and shagreen patch which is slightly elevated soft skin-coloured plaque usually found in lumbosacral region.  We report a case of TSC in a 21- year- old Saudi man with a 13 years history of asymptomatic skin lesions and generalized tonic-clonic seizures. Dermatological examination revealed facial angiofibromas, ash leaf macules, pedunculated fibromas on trunk, and shagreen patch on the back. Scalp swelling was found and confirmed to be shagreen patch by the histopathology findings. In conclusion, scalp shagreen patch is an unusual presentation of TSC. It should be considered in clinical examination of suspected cases of TSC with relevant histopathology to confirm the lesion.


2012 ◽  
Vol 1 (1) ◽  
pp. 29-34
Author(s):  
Maryam Hadibarhaghtalab ◽  
Nezam Hadibarhaghtalab ◽  
Ali Reza Manafi

Introduction: Cyclic vomiting syndrome (CVS) is characterized by recurrent episodes of intense nausea and vomiting interpreted with symptom free period. As data regarding the pattern of disease in our region is scarce, we performed this study to investigate the pattern of pediatric cyclic vomiting in Shiraz, southern Iran. Methods and Patients: This study was performed in Nemazee Hospital, territory health care center affiliated with Shiraz University of Medical Sciences from 2000 to 2010. Medical files were reviewed and data was collected by means of a checklist. Patients were divided into two groups including 1-13 years of age as children and those 13-18 years of age as adolescents. Results: Overall, 43 patients with CVS were included, among whom there were 26 (60.5%) females. The mean age at first attack was found to be 6.2 (3.7) years. Ten patients (23.3%) had a family history of migraine among which there were 8 females. The most common clinical complaint was found to be abdominal pain in 32 (74.4%) patients. GI (gastrointestinal) disorders were more common in the adolescent group rather than the children group (p=0.007).The most common trigger factor was upper respiratory tract infection (URI) detected in 13 patients (30.2%).The most associated disorder was abdominal migraine in 5 (11.6%) patients. Anemia was more common in the adolescent group (p=0.009) than in the children’s group .There were no radiological and laboratory abnormalities among these patients. The most commonly used medications were anti-migraines in 31 (72.0%) patients.Conclusion: as there is no definite drug for CVS, knowing the common trigger factors which culminate in CVS in each region can be of great importance and can prevent attacks in the prodromal phase. [GMJ. 2012;1(1):29-34]


Author(s):  
Olasseri K. R. Mariyath ◽  
Sreekanth Sukumarakurup ◽  
Koyakutty A. Samad ◽  
Keerankulangara Devi ◽  
George Nikhil ◽  
...  

<p class="abstract">Cutaneous manifestations observed in COVID-19 include maculopapular rash, urticaria, pseudo chilblain, vesicles, livedo reticularis, petechiae, erythema multiforme-like, symmetric drug related intertriginous and flexural exanthem (SDRIFE)-like and pityriasis rosea-like lesions. Maculopapular rash involving the trunk and sparing palms and soles is the most common cutaneous manifestation reported in COVID-19 patients. We report cutaneous manifestations in six COVID-19 patients from the corona isolation ward and intensive care unit of a tertiary care center for COVID-19 management in Kerala, South India. The skin lesions observed were urticaria (two patients), atypical maculopapular rash with urticarial and erythema multiforme-like lesions, eruptive pseudoangiomatosis, exaggerated insect bite reaction and acute localized exanthematous pustulosis (ALEP)-like lesions. To the best of our knowledge atypical maculopapular rash with urticarial and erythema multiforme-like lesions, eruptive pseudoangiomatosis and acute localized exanthematous pustulosis-like lesions are not reported in COVID-19.</p>


2021 ◽  
Vol 79 (4) ◽  
pp. 315-320
Author(s):  
Renan Minotto ◽  
Joana R. Fitz ◽  
Bruna M. Bauer ◽  
Ana Helena Choi

Introduction: Coronavirus disease 2019 (COVID-19) predominantly affects the respiratory system, but there have been many reports of skin involvement. Several cutaneous manifestations associated with COVID-19 have been identified, including acral lesions (pernio-like), which we intend to better characterize in this study. Methods: Demographic, clinical and major histopathologic characteristics of acral skin lesions occurring during the acute infection stage of COVID-19 disease were evaluated in this survey conducted in the Dermatology Division of Santa Casa Hospital Complex, Federal University of Health Sciences, Porto Alegre, Brazil. Results: In the present study, we evaluated eight female patients with acute SARS-CoV-2 infection confirmed by PCR with acral skin lesions including pernio-like. The mean age was 43.6 and with no other acute disease, who had a good outcome with need for hospitalization only in 2 cases. Pernio-like lesions were observed under hot weather conditions in patients who denied any previous history of similar cutaneous manifestations. Some acral lesions resembled those of lupus erythematosus and of herpes simplex paronychia, but laboratory tests were negative for those conditions. Unusual nail involvement was present, characterized by half-moon shaped erythematous bands at the distal margin of the lunula. Conclusion: Recognition of these skin lesions is important in that they could be potential markers, aiding in the diagnosis and prognosis of COVID-19 disease.


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